专利检索 cpc:"B01J2219/00436" 第 1 页

1.

发明授权
Method and device for producing biochemical reaction supporting materials 失效
标题翻译：生化反应辅料的生产方法及装置

公开(公告)号：US07737088B1

公开(公告)日：2010-06-15

申请号：US09763607

申请日：1999-08-27

申请人： Cord F. Stähler , Peer F. Stähler , Manfred Müller , Fritz Stähler , Hans Lindner

发明人： Cord F. Stähler , Peer F. Stähler , Manfred Müller , Fritz Stähler , Hans Lindner

IPC分类号： C40B50/14

CPC分类号： G01N21/6454 , B01J19/0046 , B01J19/0093 , B01J2219/00317 , B01J2219/00432 , B01J2219/00436 , B01J2219/00439 , B01J2219/00441 , B01J2219/00448 , B01J2219/00479 , B01J2219/00497 , B01J2219/00511 , B01J2219/00529 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00603 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00637 , B01J2219/00648 , B01J2219/00659 , B01J2219/00675 , B01J2219/00689 , B01J2219/00702 , B01J2219/00704 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B01L3/502715 , B01L3/5085 , B01L2300/0654 , B01L2300/069 , B01L2300/0816 , B01L2300/0864 , B82Y30/00 , C12N15/10 , C12P19/34 , C40B40/06 , C40B40/10 , C40B50/14 , G01N21/253 , G01N33/551 , G03F7/70216 , Y10S435/97 , Y10S435/973

摘要： The present invention relates to arrays of biochemical and/or biofunctional elements such as nucleic acids (oligonucleotides, for example) or other biomolecules on a carrier surface and methods of producing such arrays using photoactivation of predetermined areas for synthesis using an illumination matrix that is computer-controlled to generate an exposure pattern. This exposure pattern can be adjusted and monitored by computer using a light sensor matrix, for example a CCD matrix, to allow precise, controlled illumination of specific regions and therefore attachment of array building blocks to those specific regions. The methods and compositions of the invention permit spatially resolved photochemical synthesis of polymer probes on a carrier.

摘要翻译： 本发明涉及生物化学和/或生物功能元件的阵列，例如载体表面上的核酸（例如寡核苷酸）或其它生物分子，以及使用计算机的照明矩阵使用预定区域进行合成的光活化来制备此类阵列的方法 - 控制以产生曝光模式。可以使用光传感器矩阵（例如CCD矩阵）通过计算机来调整和监视该曝光图案，以允许特定区域的精确控制照明，并因此使阵列构建块附着到那些特定区域。本发明的方法和组合物允许在载体上空间分辨聚合物探针的光化学合成。

2.

发明授权
Preparation and screening of crystalline inorganic materials 失效
标题翻译：结晶无机材料的制备和筛选

公开(公告)号：US07442665B2

公开(公告)日：2008-10-28

申请号：US10772894

申请日：2004-02-04

申请人： Peter G. Schultz , Xiaodong Xiang , Isy Goldwasser , Gabriel Brice{hacek over (n)}o , Xiao-Dong Sun , Kai-An Wang

发明人： Peter G. Schultz , Xiaodong Xiang , Isy Goldwasser , Gabriel Brice{hacek over (n)}o , Xiao-Dong Sun , Kai-An Wang

IPC分类号： B01J29/06 , B01J33/00 , B05D1/06 , B05D1/36 , G01N31/10

CPC分类号： C04B35/16 , B01J19/0046 , B01J2219/00313 , B01J2219/00317 , B01J2219/00378 , B01J2219/0043 , B01J2219/00432 , B01J2219/00436 , B01J2219/00441 , B01J2219/00443 , B01J2219/00475 , B01J2219/005 , B01J2219/00511 , B01J2219/00515 , B01J2219/0052 , B01J2219/00527 , B01J2219/00531 , B01J2219/00533 , B01J2219/00536 , B01J2219/0054 , B01J2219/00585 , B01J2219/0059 , B01J2219/00592 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00619 , B01J2219/00621 , B01J2219/00626 , B01J2219/00628 , B01J2219/0063 , B01J2219/00635 , B01J2219/00637 , B01J2219/00644 , B01J2219/00646 , B01J2219/00648 , B01J2219/00659 , B01J2219/00689 , B01J2219/00691 , B01J2219/00711 , B01J2219/0072 , B01J2219/00722 , B01J2219/00736 , B01J2219/00745 , B01J2219/00747 , B01J2219/00752 , B01J2219/00754 , B82Y25/00 , B82Y30/00 , C01G51/006 , C01G51/68 , C01P2002/34 , C01P2002/52 , C01P2002/72 , C01P2006/40 , C01P2006/42 , C04B35/01 , C04B35/4508 , C04B35/4521 , C04B35/4525 , C04B35/62218 , C04B2235/3206 , C04B2235/3208 , C04B2235/3213 , C04B2235/3215 , C04B2235/3224 , C04B2235/3225 , C04B2235/3227 , C04B2235/3262 , C04B2235/327 , C04B2235/3275 , C04B2235/3284 , C04B2235/3286 , C04B2235/3296 , C04B2235/3298 , C04B2235/3418 , C04B2235/3463 , C04B2235/656 , C04B2235/761 , C04B2235/762 , C04B2235/768 , C04B2235/96 , C23C14/042 , C23C14/087 , C23C16/042 , C40B30/08 , C40B40/14 , C40B40/18 , C40B60/08 , C40B60/14 , C40B70/00 , C40B80/00 , G01R33/16 , H01F1/401 , H01F1/407 , H01F10/007 , H01F10/1933 , H01F41/18 , H01F41/34 , H01L43/10 , Y10T428/24479 , Y10T428/24612 , Y10T428/2462 , Y10T428/31 , Y10T428/31645 , Y10T428/31855 , Y10T428/31931 , Y10T436/25 , Y10T436/2525 , Y10T436/255 , Y10T436/25875

摘要： Methods and apparatus for the preparation and use of a substrate having an array of diverse materials in predefined regions thereon. A substrate having an array of diverse materials thereon is generally prepared by delivering components of materials to predefined regions on a substrate, and simultaneously reacting the components to form at least two materials. Materials which can be prepared using the methods and apparatus of the present invention include, for example, covalent network solids, ionic solids and molecular solids. More particularly, materials which can be prepared using the methods and apparatus of the present invention include, for example, inorganic materials, intermetallic materials, metal alloys, ceramic materials, organic materials, organometallic materials, non-biological organic polymers, composite materials (e.g., inorganic composites, organic composites, or combinations thereof), etc. Once prepared, these materials can be screened for useful properties including, for example, electrical, thermal, mechanical, morphological, optical, magnetic, chemical, or other properties. Thus, the present invention provides methods for the parallel synthesis and analysis of novel materials having useful properties.

摘要翻译： 用于制备和使用在其上的预定区域中具有不同材料阵列的基材的方法和装置。通常通过将材料的组分递送到衬底上的预定区域，并且同时使组分反应以形成至少两种材料来制备其上具有不同材料阵列的衬底。可以使用本发明的方法和装置制备的材料包括例如共价网络固体，离子固体和分子固体。更具体地，可以使用本发明的方法和装置制备的材料包括例如无机材料，金属间材料，金属合金，陶瓷材料，有机材料，有机金属材料，非生物有机聚合物，复合材料（例如，无机复合材料，有机复合材料或其组合）等。一旦制备，可以对这些材料进行筛选以获得有用的性质，包括例如电，热，机械，形态，光学，磁性，化学或其它性质。因此，本发明提供了用于并行合成和分析具有有用特性的新型材料的方法。

3.

发明授权
Sequencing of surface immobilized polymers utilizing microflourescence detection 失效
标题翻译：利用微量荧光检测对表面固定化聚合物进行测序

公开(公告)号：US07329496B2

公开(公告)日：2008-02-12

申请号：US11325809

申请日：2006-01-05

申请人： William J. Dower , Stephen P. A. Fodor

发明人： William J. Dower , Stephen P. A. Fodor

IPC分类号： C12Q1/68

CPC分类号： B01J19/0046 , B01J2219/00315 , B01J2219/00432 , B01J2219/00434 , B01J2219/00436 , B01J2219/00459 , B01J2219/00468 , B01J2219/00475 , B01J2219/005 , B01J2219/00527 , B01J2219/00529 , B01J2219/00531 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00648 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B01L7/52 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07H19/10 , C07H21/00 , C07K1/042 , C07K1/045 , C07K17/06 , C07K17/14 , C12Q1/6804 , C12Q1/6809 , C12Q1/6816 , C12Q1/6823 , C12Q1/6837 , C12Q1/6869 , C12Q1/6874 , C12Q2535/101 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/1475 , G03F7/00 , G03F7/26 , G03F7/265 , G03F7/38 , G11C13/0014 , G11C13/0019 , C12Q2537/157 , C12Q2533/101 , C12Q2565/537 , C12Q2563/107 , C12Q2565/513 , C12Q2537/143 , C12Q2565/518

摘要： Means for simultaneous parallel sequence analysis of a large number of biological polymer macromolecules. Apparatus and methods may use fluorescent labels in repetitive chemistry to determine terminal monomers on solid phase immobilized polymers. Reagents which specifically recognize terminal monomers are used to label polymers at defined positions on a solid substrate.

摘要翻译： 用于同时并行序列分析大量生物聚合物大分子的方法。装置和方法可以在重复化学中使用荧光标记物来测定固相固定化聚合物上的末端单体。专门识别末端单体的试剂用于在固体基质上的限定位置上标记聚合物。

4.

发明申请
Aerosol jet deposition method and system for creating a reference region/sample region on a biosensor 审中-公开
标题翻译：气溶胶喷射沉积方法和用于在生物传感器上产生参考区域/样品区域的系统

公开(公告)号：US20070264155A1

公开(公告)日：2007-11-15

申请号：US11431226

申请日：2006-05-09

申请人： Michael Brady , John Peanasky , Richard Peterson , Yongsheng Yan

发明人： Michael Brady , John Peanasky , Richard Peterson , Yongsheng Yan

IPC分类号： G01N31/22

CPC分类号： B01J19/0046 , B01J2219/0036 , B01J2219/00436 , B01J2219/00527 , B01J2219/00576 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/00637 , B01J2219/00659 , B01J2219/00662 , B01J2219/00677 , B01J2219/00693 , B01J2219/00702 , B01J2219/0072 , B01J2219/00725 , B01L3/0268 , B01L2200/0636 , B01L2300/0819

摘要： A method and deposition device are described herein that use an aerosol jet direct write technique to create non-binding reference region(s) and/or binding sample region(s) within a single well or multiple wells of a microplate, or on a single or multiple biosensors of an unassembled bottom insert.

摘要翻译： 本文描述了一种方法和沉积装置，其使用气溶胶射流直接写入技术来在微孔板的单个孔或多个孔内或单个单个孔上产生非结合参考区域和/或结合样品区域或未组装的底部插入物的多个生物传感器。

5.

发明授权
Electrospraying apparatus and method for coating particles 有权
标题翻译：电喷雾装置和涂布颗粒的方法

公开(公告)号：US07279322B2

公开(公告)日：2007-10-09

申请号：US10809660

申请日：2004-03-25

申请人： David Y. H. Pui , Da-Ren Chen

发明人： David Y. H. Pui , Da-Ren Chen

IPC分类号： C12N15/88

CPC分类号： B01J2/006 , A61K39/00 , A61K48/00 , B01J2/04 , B01J2219/00371 , B01J2219/00436 , B05B5/025 , B05B5/03 , B05B5/0533 , B05B5/081 , B05B5/082 , B05B5/084 , B05B5/087 , B05B13/04 , C12M35/02 , C12N15/8207 , C12N15/87 , C12N15/895

摘要： An electrospraying apparatus and/or method is used to coat particles. For example, a flow including at least one liquid suspension may be provided through at least one opening at a spray dispenser end. The flow includes at least particles and a coating material. A spray of microdroplets suspending at least the particles is established forward of the spray dispenser end by creating a nonuniform electrical field between the spray dispenser end and an electrode electrically isolated therefrom. The particles are coated with at least a portion of the coating material as the microdroplet evaporates. For example, the suspension may include biological material particles.

摘要翻译： 使用电喷雾装置和/或方法来涂覆颗粒。例如，可以通过喷雾分配器端部的至少一个开口提供包括至少一个液体悬浮液的流。流动至少包括颗粒和涂层材料。通过在喷雾分配器端部与与其分离的电极之间产生不均匀的电场，在喷雾分配器端的前方建立悬浮至少颗粒的微滴喷雾。当微滴蒸发时，颗粒被涂覆有至少一部分涂层材料。例如，悬浮液可以包括生物材料颗粒。

6.

发明申请
Microarray having a base cleavable sulfonyl linker 有权
标题翻译：具有碱基可裂解磺酰接头的微阵列

公开(公告)号：US20070202509A1

公开(公告)日：2007-08-30

申请号：US11361160

申请日：2006-02-24

申请人： Dominic Suciu , Hetian Gao

发明人： Dominic Suciu , Hetian Gao

IPC分类号： C12Q1/68 , C07H21/04 , C12M3/00

CPC分类号： C40B50/18 , B01J19/0046 , B01J2219/00378 , B01J2219/00432 , B01J2219/00436 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00626 , B01J2219/00637 , B01J2219/00639 , B01J2219/00722 , B01J2219/00725 , C40B40/06

摘要： The present invention provides a microarray having base cleavable, sulfonyl-containing linkers and a process to make the microarray. Oligonucleotides of any sequence may be synthesized on the microarray having the cleavable linker. The oligonucleotides may be cleaved and recovered as a pool of oligonucleotides having a three prime phosphate moiety. Specifically, the microarray is an electrode containing microarray, and the oligonucleotides are electrochemically synthesized.

摘要翻译： 本发明提供了具有碱基可切割的含磺酰基接头的微阵列和制备微阵列的方法。可以在具有可切割接头的微阵列上合成任何序列的寡核苷酸。可以将寡核苷酸切割并作为具有三原子磷酸酯部分的寡核苷酸库回收。具体地，微阵列是含有微阵列的电极，并且寡核苷酸是电化学合成的。