-
公开(公告)号:US20050170340A9
公开(公告)日:2005-08-04
申请号:US10102915
申请日:2002-03-22
申请人: Stephen Fodor , Dennis Solas , William Dower
发明人: Stephen Fodor , Dennis Solas , William Dower
IPC分类号: B01J19/00 , C07B61/00 , C07H19/10 , C07H21/00 , C07K1/04 , C07K17/06 , C07K17/14 , C12Q1/68 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/14 , G03F7/00 , G03F7/26 , G03F7/38 , G11C13/02 , C12M1/34 , G01N33/53 , G01N33/542
CPC分类号: G03F7/00 , B01J19/0046 , B01J2219/00315 , B01J2219/00432 , B01J2219/00434 , B01J2219/00436 , B01J2219/00459 , B01J2219/00468 , B01J2219/00475 , B01J2219/005 , B01J2219/00527 , B01J2219/00529 , B01J2219/00531 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00641 , B01J2219/00648 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07H19/10 , C07H21/00 , C07K1/042 , C07K1/045 , C07K17/06 , C07K17/14 , C12Q1/6804 , C12Q1/6809 , C12Q1/6816 , C12Q1/6827 , C12Q1/6834 , C12Q1/6837 , C12Q1/6874 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/1475 , G03F7/265 , G03F7/38 , G11C13/0014 , G11C13/0019 , C12Q2565/513 , C12Q2565/507 , C12Q2545/101 , C12Q2525/185 , C12Q2565/514 , C12Q2563/173 , C12Q2563/119 , C12Q2563/149 , C12Q2525/151 , C12Q2525/179 , C12Q2525/204
摘要: The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and to characterize their sources.
摘要翻译: 本发明提供了用于测序,指纹和绘制生物大分子(通常为生物聚合物)的方法和装置。 该方法利用多种序列特异性识别试剂,其也可用于生物样品的分类和表征其来源。
-
2.Sequencing of surface immobilized polymers utilizing microflourescence detection 失效
标题翻译: 利用微量荧光检测对表面固定化聚合物进行测序公开(公告)号:US20060172327A1
公开(公告)日:2006-08-03
申请号:US11325809
申请日:2006-01-05
申请人: William Dower , Stephen Fodor
发明人: William Dower , Stephen Fodor
CPC分类号: B01J19/0046 , B01J2219/00315 , B01J2219/00432 , B01J2219/00434 , B01J2219/00436 , B01J2219/00459 , B01J2219/00468 , B01J2219/00475 , B01J2219/005 , B01J2219/00527 , B01J2219/00529 , B01J2219/00531 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00648 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B01L7/52 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07H19/10 , C07H21/00 , C07K1/042 , C07K1/045 , C07K17/06 , C07K17/14 , C12Q1/6804 , C12Q1/6809 , C12Q1/6816 , C12Q1/6823 , C12Q1/6837 , C12Q1/6869 , C12Q1/6874 , C12Q2535/101 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/1475 , G03F7/00 , G03F7/26 , G03F7/265 , G03F7/38 , G11C13/0014 , G11C13/0019 , C12Q2537/157 , C12Q2533/101 , C12Q2565/537 , C12Q2563/107 , C12Q2565/513 , C12Q2537/143 , C12Q2565/518
摘要: Means for simultaneous parallel sequence analysis of a large number of biological polymer macromolecules. Apparatus and methods may use fluorescent labels in repetitive chemistry to determine terminal monomers on solid phase immobilized polymers. Reagents which specifically recognize terminal monomers are used to label polymers at defined positions on a solid substrate.
摘要翻译: 用于同时并行序列分析大量生物聚合物大分子的方法。 装置和方法可以在重复化学中使用荧光标记物来测定固相固定化聚合物上的末端单体。 专门识别末端单体的试剂用于在固体基质上的限定位置上标记聚合物。
-
公开(公告)号:US20050112676A1
公开(公告)日:2005-05-26
申请号:US10993432
申请日:2004-11-22
申请人: Stephen Fodor , Dennis Solas , William Dower
发明人: Stephen Fodor , Dennis Solas , William Dower
IPC分类号: B01J19/00 , C07B61/00 , C07H19/10 , C07H21/00 , C07K1/04 , C07K17/06 , C07K17/14 , C12Q1/68 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/14 , G03F7/00 , G03F7/26 , G03F7/38 , G11C13/02 , G01N33/53 , G01N33/542
CPC分类号: G03F7/00 , B01J19/0046 , B01J2219/00315 , B01J2219/00432 , B01J2219/00434 , B01J2219/00436 , B01J2219/00459 , B01J2219/00468 , B01J2219/00475 , B01J2219/005 , B01J2219/00527 , B01J2219/00529 , B01J2219/00531 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00641 , B01J2219/00648 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07H19/10 , C07H21/00 , C07K1/042 , C07K1/045 , C07K17/06 , C07K17/14 , C12Q1/6804 , C12Q1/6809 , C12Q1/6816 , C12Q1/6827 , C12Q1/6834 , C12Q1/6837 , C12Q1/6874 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/1475 , G03F7/265 , G03F7/38 , G11C13/0014 , G11C13/0019 , C12Q2565/513 , C12Q2565/507 , C12Q2545/101 , C12Q2525/185 , C12Q2565/514 , C12Q2563/173 , C12Q2563/119 , C12Q2563/149 , C12Q2525/151 , C12Q2525/179 , C12Q2525/204
摘要: The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and to characterize their sources.
摘要翻译: 本发明提供了用于测序,指纹和绘制生物大分子(通常为生物聚合物)的方法和装置。 该方法利用多种序列特异性识别试剂,其也可用于生物样品的分类和表征其来源。
-
公开(公告)号:US20050053928A9
公开(公告)日:2005-03-10
申请号:US10125530
申请日:2002-04-19
申请人: Stephen Fodor , Dennis Solas , William Dower
发明人: Stephen Fodor , Dennis Solas , William Dower
IPC分类号: B01J19/00 , C07B61/00 , C07H19/10 , C07H21/00 , C07K1/04 , C07K17/06 , C07K17/14 , C12Q1/68 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/14 , G03F7/00 , G03F7/26 , G03F7/38 , G11C13/02 , C12M1/34 , G01N33/53 , G01N33/542
CPC分类号: G03F7/00 , B01J19/0046 , B01J2219/00315 , B01J2219/00432 , B01J2219/00434 , B01J2219/00436 , B01J2219/00459 , B01J2219/00468 , B01J2219/00475 , B01J2219/005 , B01J2219/00527 , B01J2219/00529 , B01J2219/00531 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00641 , B01J2219/00648 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07H19/10 , C07H21/00 , C07K1/042 , C07K1/045 , C07K17/06 , C07K17/14 , C12Q1/6804 , C12Q1/6809 , C12Q1/6816 , C12Q1/6827 , C12Q1/6834 , C12Q1/6837 , C12Q1/6874 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/1475 , G03F7/265 , G03F7/38 , G11C13/0014 , G11C13/0019 , C12Q2565/513 , C12Q2565/507 , C12Q2545/101 , C12Q2525/185 , C12Q2565/514 , C12Q2563/173 , C12Q2563/119 , C12Q2563/149 , C12Q2525/151 , C12Q2525/179 , C12Q2525/204
摘要: The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and to characterize their sources.
-
公开(公告)号:US20050009014A9
公开(公告)日:2005-01-13
申请号:US10102774
申请日:2002-03-22
申请人: Stephen Fodor , Dennis Solas , William Dower
发明人: Stephen Fodor , Dennis Solas , William Dower
IPC分类号: B01J19/00 , C07B61/00 , C07H19/10 , C07H21/00 , C07K1/04 , C07K17/06 , C07K17/14 , C12Q1/68 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/14 , G03F7/00 , G03F7/26 , G03F7/38 , G11C13/02 , C12M1/34 , G01N33/53 , G01N33/542
CPC分类号: G03F7/00 , B01J19/0046 , B01J2219/00315 , B01J2219/00432 , B01J2219/00434 , B01J2219/00436 , B01J2219/00459 , B01J2219/00468 , B01J2219/00475 , B01J2219/005 , B01J2219/00527 , B01J2219/00529 , B01J2219/00531 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00641 , B01J2219/00648 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07H19/10 , C07H21/00 , C07K1/042 , C07K1/045 , C07K17/06 , C07K17/14 , C12Q1/6804 , C12Q1/6809 , C12Q1/6816 , C12Q1/6827 , C12Q1/6834 , C12Q1/6837 , C12Q1/6874 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/1475 , G03F7/265 , G03F7/38 , G11C13/0014 , G11C13/0019 , C12Q2565/513 , C12Q2565/507 , C12Q2545/101 , C12Q2525/185 , C12Q2565/514 , C12Q2563/173 , C12Q2563/119 , C12Q2563/149 , C12Q2525/151 , C12Q2525/179 , C12Q2525/204
摘要: The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and to characterize their sources.
-
6.Sequencing of surface immobilized polymers utilizing microfluorescence detection 失效
标题翻译: 利用微荧光检测法测定表面固定化聚合物公开(公告)号:US20070105131A1
公开(公告)日:2007-05-10
申请号:US11446575
申请日:2006-06-02
申请人: William Dower , Stephen Fodor
发明人: William Dower , Stephen Fodor
IPC分类号: C12Q1/68
CPC分类号: B01J19/0046 , B01J2219/00315 , B01J2219/00432 , B01J2219/00434 , B01J2219/00436 , B01J2219/00459 , B01J2219/00468 , B01J2219/00475 , B01J2219/005 , B01J2219/00527 , B01J2219/00529 , B01J2219/00531 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00648 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B01L7/52 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07H19/10 , C07H21/00 , C07K1/042 , C07K1/045 , C07K17/06 , C07K17/14 , C12Q1/6804 , C12Q1/6809 , C12Q1/6816 , C12Q1/6823 , C12Q1/6837 , C12Q1/6869 , C12Q1/6874 , C12Q2535/101 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/1475 , G03F7/00 , G03F7/26 , G03F7/265 , G03F7/38 , G11C13/0014 , G11C13/0019 , C12Q2537/157 , C12Q2533/101 , C12Q2565/537 , C12Q2563/107 , C12Q2565/513 , C12Q2537/143 , C12Q2565/518
摘要: Means for simultaneous parallel sequence analysis of a large number of biological polymer macromolecules. Apparatus and methods may use fluorescent labels in repetitive chemistry to determine terminal monomers on solid phase immobilized polymers. Reagents which specifically recognize terminal monomers are used to label polymers at defined positions on a solid substrate.
摘要翻译: 用于同时并行序列分析大量生物聚合物大分子的方法。 装置和方法可以在重复化学中使用荧光标记物来测定固相固定化聚合物上的末端单体。 专门识别末端单体的试剂用于在固体基质上的限定位置上标记聚合物。
-
公开(公告)号:US20050164249A1
公开(公告)日:2005-07-28
申请号:US10992772
申请日:2004-11-22
申请人: Stephen Fodor , Dennis Solas , William Dower
发明人: Stephen Fodor , Dennis Solas , William Dower
IPC分类号: B01J19/00 , C07B61/00 , C07H19/10 , C07H21/00 , C07K1/04 , C07K17/06 , C07K17/14 , C12Q1/68 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/14 , G03F7/00 , G03F7/26 , G03F7/38 , G11C13/02 , C12M1/34 , G01N33/53
CPC分类号: G03F7/00 , B01J19/0046 , B01J2219/00315 , B01J2219/00432 , B01J2219/00434 , B01J2219/00436 , B01J2219/00459 , B01J2219/00468 , B01J2219/00475 , B01J2219/005 , B01J2219/00527 , B01J2219/00529 , B01J2219/00531 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00641 , B01J2219/00648 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07H19/10 , C07H21/00 , C07K1/042 , C07K1/045 , C07K17/06 , C07K17/14 , C12Q1/6804 , C12Q1/6809 , C12Q1/6816 , C12Q1/6827 , C12Q1/6834 , C12Q1/6837 , C12Q1/6874 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/1475 , G03F7/265 , G03F7/38 , G11C13/0014 , G11C13/0019 , C12Q2565/513 , C12Q2565/507 , C12Q2545/101 , C12Q2525/185 , C12Q2565/514 , C12Q2563/173 , C12Q2563/119 , C12Q2563/149 , C12Q2525/151 , C12Q2525/179 , C12Q2525/204
摘要: The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and to characterize their sources.
-
公开(公告)号:US20050158743A1
公开(公告)日:2005-07-21
申请号:US10992782
申请日:2004-11-22
申请人: Stephen Fodor , Dennis Solas , William Dower
发明人: Stephen Fodor , Dennis Solas , William Dower
IPC分类号: B01J19/00 , C07B61/00 , C07H19/10 , C07H21/00 , C07K1/04 , C07K17/06 , C07K17/14 , C12Q1/68 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/14 , G03F7/00 , G03F7/26 , G03F7/38 , G11C13/02 , C12M1/34 , G01N33/53
CPC分类号: G03F7/00 , B01J19/0046 , B01J2219/00315 , B01J2219/00432 , B01J2219/00434 , B01J2219/00436 , B01J2219/00459 , B01J2219/00468 , B01J2219/00475 , B01J2219/005 , B01J2219/00527 , B01J2219/00529 , B01J2219/00531 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00641 , B01J2219/00648 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07H19/10 , C07H21/00 , C07K1/042 , C07K1/045 , C07K17/06 , C07K17/14 , C12Q1/6804 , C12Q1/6809 , C12Q1/6816 , C12Q1/6827 , C12Q1/6834 , C12Q1/6837 , C12Q1/6874 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/1475 , G03F7/265 , G03F7/38 , G11C13/0014 , G11C13/0019 , C12Q2565/513 , C12Q2565/507 , C12Q2545/101 , C12Q2525/185 , C12Q2565/514 , C12Q2563/173 , C12Q2563/119 , C12Q2563/149 , C12Q2525/151 , C12Q2525/179 , C12Q2525/204
摘要: The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and to characterize their sources.
-
9.Sequence of surface immobilized polymers utilizing microfluorescence detection 审中-公开
标题翻译: 使用微荧光检测的表面固定化聚合物的顺序公开(公告)号:US20050148002A1
公开(公告)日:2005-07-07
申请号:US10996692
申请日:2004-11-23
申请人: William Dower , Stephen Fodor
发明人: William Dower , Stephen Fodor
IPC分类号: G01N33/48 , B01J19/00 , B01J19/08 , B01L7/00 , B05D3/00 , C07B51/00 , C07B61/00 , C07C231/02 , C07C237/22 , C07H19/10 , C07H21/00 , C07K1/04 , C07K1/06 , C07K7/06 , C07K14/00 , C07K16/00 , C07K17/02 , C07K17/06 , C07K17/08 , C07K17/14 , C12M1/34 , C12Q1/68 , C40B30/04 , C40B40/06 , C40B40/10 , C40B60/14 , G01N1/30 , G01N15/14 , G01N21/64 , G01N33/53 , G01N33/533 , G01N33/536 , G01N33/541 , G01N33/543 , G01N33/566 , G01N33/58 , G01N37/00 , G03F7/00 , G03F7/26 , G03F7/38 , G11C13/02 , C07H21/04
CPC分类号: B01J19/0046 , B01J2219/00315 , B01J2219/00432 , B01J2219/00434 , B01J2219/00436 , B01J2219/00459 , B01J2219/00468 , B01J2219/00475 , B01J2219/005 , B01J2219/00527 , B01J2219/00529 , B01J2219/00531 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00648 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B01L7/52 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07H19/10 , C07H21/00 , C07K1/042 , C07K1/045 , C07K17/06 , C07K17/14 , C12Q1/6804 , C12Q1/6809 , C12Q1/6816 , C12Q1/6823 , C12Q1/6837 , C12Q1/6869 , C12Q1/6874 , C12Q2535/101 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/1475 , G03F7/00 , G03F7/26 , G03F7/265 , G03F7/38 , G11C13/0014 , G11C13/0019 , C12Q2537/157 , C12Q2533/101 , C12Q2565/537 , C12Q2563/107 , C12Q2565/513 , C12Q2537/143 , C12Q2565/518
摘要: Means for simultaneous parallel sequence analysis of a large number of biological polymer macromolecules. Apparatus and methods may use fluorescent labels in repetitive chemistry to determine terminal manomers on solid phase immobilized polymers. Reagents which specifically recognize terminal manomers are used to label polymers at defined positions on a solid substrate.
摘要翻译: 用于同时并行序列分析大量生物聚合物大分子的方法。 仪器和方法可以在重复化学中使用荧光标记物来测定固相固定化聚合物上的末端起始物。 用于特异性识别末端异构体的试剂用于在固体基质上的限定位置上标记聚合物。
-
公开(公告)号:US20060251803A1
公开(公告)日:2006-11-09
申请号:US11369372
申请日:2006-03-06
申请人: John Huizinga , Vincent King , John Strand , James Dobbs , Thomas Hunter , William Dower , Daniel Carlson , Serge Wetzels , Samual Hunter , Thelma Hunter
发明人: John Huizinga , Vincent King , John Strand , James Dobbs , Thomas Hunter , William Dower , Daniel Carlson , Serge Wetzels , Samual Hunter , Thelma Hunter
IPC分类号: B05D5/06
CPC分类号: B29C35/0894 , B29C35/0888 , B29C35/10 , B29C59/046 , B29C2035/0827 , B29C2043/463 , H05K1/0393 , H05K3/0008 , H05K3/0079 , H05K3/101 , H05K2201/0108 , H05K2203/0113 , H05K2203/0143 , H05K2203/1545 , H05K2203/1572
摘要: A microreplicated article is disclosed. The article includes an opaque web having first and second opposed surfaces. The first surface includes a first microreplicated structure having a plurality of first features. The second surface includes a second microreplicated structure having a plurality of second features. The first microreplicated structure and the second microreplicated structure retain registration within 100 micrometers.
摘要翻译: 公开了微复制品。 该制品包括具有第一和第二相对表面的不透明纤维网。 第一表面包括具有多个第一特征的第一微复制结构。 第二表面包括具有多个第二特征的第二微复制结构。 第一微复制结构和第二微复制结构保持配准在100微米内。
-
-
-
-
-
-
-
-
-