-
1.发明公开公开(公告)号：US20230338915A1
公开(公告)日：2023-10-26
申请号：US18026702
申请日：2021-09-20
申请人： DSM IP ASSETS B.V.
CPC分类号： B01J19/02 , B01J19/002 , B01J2219/00331 , B01J2219/00353 , B01J2219/00601 , B01J2219/00635 , B01J2219/00637 , B01J2219/0072 , B01J2219/0218 , B01J2219/0277
摘要： The present invention relates to a method of reducing the deposit of metallic transition metal, particularly palladium, on a metal part in hydrogenation reactions using hydrogen and a heterogenous supported palladium catalyst. These metallic transition metal deposit, particularly palladium deposits, are particularly formed at areas which are exposed to high velocity and shear forces of the hydrogenation mixture comprising the transition metal catalyst, particularly palladium catalyst. They are significantly reduced or even avoided when the surface of the respective metal parts are coated by a plasma sprayed ceramic coating.
-
公开(公告)号：US20230338913A1
公开(公告)日：2023-10-26
申请号：US18319356
申请日：2023-05-17
发明人： William BANYAI , Bill James PECK , Andres FERNANDEZ , Siyuan CHEN , Pierre INDERMUHLE , Eugene P. MARSH
CPC分类号： B01J19/0046 , C12N15/1093 , B01J2219/00596 , B01J2219/00722 , B01J2219/00497 , B01J2219/00585 , B01J2219/00317 , B01J2219/00511 , B01J2219/00522 , B01J2219/00635 , B01J2219/00637 , B01J2219/00662 , B01L3/50857
摘要： Devices and methods for de novo synthesis of large and highly accurate libraries of oligonucleic acids are provided herein. Devices include structures having a main channel and microchannels, where the microchannels have a high surface area to volume ratio. Devices disclosed herein provide for de novo synthesis of oligonucleic acids having a low error rate.
-
公开(公告)号：US11691118B2
公开(公告)日：2023-07-04
申请号：US16921712
申请日：2020-07-06
发明人： William Banyai , Bill James Peck , Andres Fernandez , Siyuan Chen , Pierre Indermuhle , Eugene P. Marsh
CPC分类号： B01J19/0046 , C12N15/1093 , B01J2219/00317 , B01J2219/00497 , B01J2219/00511 , B01J2219/00522 , B01J2219/00585 , B01J2219/00596 , B01J2219/00635 , B01J2219/00637 , B01J2219/00662 , B01J2219/00722 , B01L3/50857 , C12N15/1093 , C12Q2563/159 , C12Q2565/513 , C12Q2565/629
摘要： Devices and methods for de novo synthesis of large and highly accurate libraries of oligonucleic acids are provided herein. Devices include structures having a main channel and microchannels, where the microchannels have a high surface area to volume ratio. Devices disclosed herein provide for de novo synthesis of oligonucleic acids having a low error rate.
-
公开(公告)号：US11654411B2
公开(公告)日：2023-05-23
申请号：US17205263
申请日：2021-03-18
发明人： Mark Edward Brennan Smith , Andrea Sabot , Isabelle Marie Julia Rasolonjatovo , Jean-Ernest Sohna Sohna , Adrian Martin Horgan , Harold Philip Swerdlow
IPC分类号： B01J19/00 , C40B50/18 , C12Q1/6834 , C40B40/06 , C12Q1/6876 , C12Q1/6806 , C12Q1/6837 , C08F222/38
CPC分类号： B01J19/0046 , C08F222/38 , C12Q1/6806 , C12Q1/6834 , C12Q1/6837 , C12Q1/6876 , C40B40/06 , C40B50/18 , B01J2219/0061 , B01J2219/0072 , B01J2219/00351 , B01J2219/00527 , B01J2219/00529 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/00637 , B01J2219/00639 , B01J2219/00641 , B01J2219/00716 , B01J2219/00722 , Y10T428/265
摘要： Methods and compositions are disclosed relating to the localization of nucleic acids to arrays such as silane-free arrays, and of sequencing the nucleic acids localized thereby.
-
公开(公告)号：US20190240636A1
公开(公告)日：2019-08-08
申请号：US16384678
申请日：2019-04-15
IPC分类号： B01J19/00
CPC分类号： B01J19/0046 , B01J2219/00317 , B01J2219/00432 , B01J2219/00441 , B01J2219/00596 , B01J2219/00608 , B01J2219/0061 , B01J2219/00619 , B01J2219/00637 , B01J2219/00693 , B01J2219/00711 , B01J2219/00722
摘要： Compositions, devices, methods and systems are provided for differential functionalization of a surface of a structure to support biopolymer synthesis. Provided herein are processes which include use of lamps, lasers, and/or microcontact printing to add functional groups to surfaces for the efficient and uniform synthesis of oligonucleic acids.
-
公开(公告)号：US20180304221A1
公开(公告)日：2018-10-25
申请号：US15770299
申请日：2016-10-21
发明人： Alan Gordon GOODYEAR , Barry BEROTH
IPC分类号： B01J19/00
CPC分类号： B01J19/0046 , B01J19/00 , B01J2219/00315 , B01J2219/00317 , B01J2219/00635 , B01J2219/00637 , B01J2219/00659 , B01L3/5085 , B01L2200/12 , B01L2300/0636 , B01L2300/0829 , B01L2300/163 , B81C1/00206
摘要： An activated textured surface comprising a plurality of energetic moieties adapted to bind biomolecules on microfeatures and/or microstructures of the activated textured surface. The microfeatures and/or microstructures provide an increase in surface area. The activated textured surface may comprise microstructures without microfeatures, or in some cases, microstructures are disposed in and/or between at least a portion of the microfeatures. The activated textured surface may be a part of a microarray substrate. Activation of the surface molecules of the microfeatures and/or microstructures using electromagnetic radiation or plasma may be used to create the energetic moieties on the activated textured surface.
-
公开(公告)号：US20180266932A1
公开(公告)日：2018-09-20
申请号：US15571808
申请日：2016-04-29
发明人： Andrea VALSESIA , Cloé DESMET , Pascal COLPO , François ROSSI
IPC分类号： G01N15/02
CPC分类号： G01N15/0227 , B01J2219/00619 , B01J2219/00621 , B01J2219/00635 , B01J2219/00637 , G01N15/00 , G01N15/0205 , G01N2015/0038
摘要： A nanoparticle screening chip and a method using said chip allowing for determining physical properties of nanoparticles, wherein the screening chip comprises a substrate having a working surface divided into a plurality of areas, wherein (1) each of these areas presents different surface properties defined by surface energy component (d,b,a), the total free energy γTOT of the surface of each area being defined as follows: γTOT=γLW+2(γ+γ−)0.5, wherein the components are: γLW=dispersive component=d, γ+=electron acceptor component=b, γ−=electron donor component=a; and (2) each of these areas comprises a plurality of subareas, each subarea comprising an array of sub-micrometric holes or elongated grooves with a different aperture size (S1, S2, S3, . . . ).
-
公开(公告)号：US20180207920A1
公开(公告)日：2018-07-26
申请号：US15745092
申请日：2016-07-13
申请人： Illumina, Inc.
IPC分类号： B32B27/30 , C08L33/26 , B01J19/00 , B01L3/00 , C12Q1/6837 , C12Q1/6876
CPC分类号： B32B27/308 , B01J19/0046 , B01J2219/00317 , B01J2219/00621 , B01J2219/00637 , B01J2219/00641 , B01J2219/00644 , B01J2219/00722 , B01L3/505 , B01L2200/0668 , B01L2200/12 , B01L2300/069 , B01L2300/0822 , B01L2300/0829 , B01L2300/0893 , B01L2300/0896 , C08L33/26 , C08L2203/02 , C12Q1/6837 , C12Q1/6874 , C12Q1/6876 , C12Q2523/101 , C12Q2527/137 , C12Q2565/607
摘要： Embodiments of the present application relate to patterned polymer sheets and processes to prepare the same for sequencing applications. In particular, flexible micro- and nano-patterned polymer sheets are prepared and used as a template surface in sequencing reaction and new polish-free methods of forming isolated hydrogel plugs in nanowells are described.
-
公开(公告)号：US20180169652A1
公开(公告)日：2018-06-21
申请号：US15737013
申请日：2016-06-20
申请人： IMEC VZW
发明人： Benjamin Jones , Tim Stakenborg , Paolo Fiorini
IPC分类号： B01L3/00
CPC分类号： B01L3/502707 , B01J2219/00353 , B01J2219/00389 , B01J2219/00414 , B01J2219/00418 , B01J2219/00637 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/502746 , B01L2200/0689 , B01L2300/0636 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/16 , B01L2400/0406 , B01L2400/0487 , B01L2400/0688 , B01L2400/086 , B05C7/04 , F16K99/0021
摘要： A fluidic device is described for locally coating an inner surface of a fluidic channel. The fluidic device comprises a first, a second and a third fluidic channel intersecting at a common junction. The first fluidic channel is connectable to a coating fluid reservoir and the third fluidic channel is connectable to a sample fluid reservoir. The fluidic device further comprises a fluid control means configured for creating a fluidic flow path for a coating fluid at the common junction such that, when coating, a coating fluid propagates from the first to the second fluidic channel via the common junction without propagating into the third fluidic channel. A corresponding method for coating and for sensing also has been disclosed.
-
公开(公告)号：US09939424B2
公开(公告)日：2018-04-10
申请号：US14550353
申请日：2014-11-21
发明人： Paul C Bridgman , Stephen G Turney
CPC分类号： G01N33/4833 , B01J19/0046 , B01J2219/00441 , B01J2219/00605 , B01J2219/00612 , B01J2219/00637 , B01J2219/00725 , B01J2219/00743 , C12M23/10 , C40B50/18 , G03F7/085 , G03F7/09
摘要： Methods and apparatuses for generating microscopic patterns of macromolecules such as proteins on a solid surface are described. Pulsed laser light is used to alter surface portions of a solid surface substrate in a predetermined pattern by removing macromolecules from surface portions of the substrate where the light is focused. The same wavelength light at lower intensity can be used to visualize the removal by its reflection from the specimen surface along the path to the detector. Select macromolecules introduced to the substrate selectively adhere to select surface portions, thereby depositing macromolecules in the predetermined pattern on the solid surface.
-
-
-
-
-
-
-
-
-
搜索结果
2756 条记录 (耗时 0.032 秒)
