Abstract:
An automated computer-controlled sampling system and related methods for collecting, processing, and analyzing agricultural samples for various chemical properties such as plant available nutrients. The sampling system allows multiple samples to be processed and analyzed for different analytes or chemical properties in a simultaneous concurrent or semi-concurrent manner. Advantageously, the system can process soil samples in the “as collected” condition without drying or grinding. The system generally includes a sample preparation sub-system which receives soil samples collected by a probe collection sub-system and produces a slurry (i.e. mixture of soil, vegetation, and/or manure and water), and a chemical analysis sub-system which processes the prepared slurry samples for quantifying multiple analytes and/or chemical properties of the sample. The sample preparation and chemical analysis sub-systems can be used to analyze soil, vegetation, and/or manure samples.
Abstract:
Systems, devices, and methods are described herein for an auxiliary heat exchange system for use in scientific sampling. In one aspect, a heat exchange system may include at least one first conduit housed in an external casing, that is removably attachable to a heat/cooling system of a vehicle. Another conduit, such as a tracer tube, may be positioned proximate to the first conduit and housed in the external casing for at least a partial length of the first conduit. The tracer conduit may include a first end that is removably attachable to a gas collection device and a second end removably attachable to a measuring device. The first conduit may be configured to carry heated liquid from the heating/cooling system of the vehicle to maintain at least a threshold temperature of gas samples in the tracer conduit to prevent or reduce the formation of condensates in the tracer conduit.
Abstract:
The invention provides columns (including pipette tip columns) and automated methods for the purification of nucleic acids including plasmids. Nucleic acids can be purified from unclarified, clarified or partially-clarified cell lysates that contain cell debris. The columns typically include a bed of medium positioned above a bottom frit and with an optional top frit. Plasmid preparation scales include miniprep, midiprep, maxiprep, megaprep and gigaprep.
Abstract:
The present invention provides a disposable ultra-filtration system comprising a disposable pipetting tip and a disposable ultra-filtration cartridge, wherein the cartridge includes a membrane filtration chamber and a dead-end channel. In use, a piston in the pipette pressurizes air within the channel; the pressurized air can subsequently move the piston and cause a reverse flow back through the membrane of the cartridge, unplugging the pores thereof. Also disclosed is an automated workstation incorporating the disposable ultra-filtration system, and a system comprising the automated workstation, useful for measuring the free therapeutic drug concentration and free hormone concentration in a sample.
Abstract:
The automated sampling system has a water tight case that encloses a testing instrument. In the preferred embodiment, the testing instrument is a field-portable ion chromatography instrument designed to test water samples. In operation, a controller directs a syringe pump to draw fluid from outside the system through a specialized filter with a continuous flow lower reservoir. When directed by the controller, the syringe pump then injects the sample water into a testing portion of the field-portable ion chromatography instrument.
Abstract:
A cell processing apparatus includes a storage container that contains liquid L including a biological sample; a filter that prevents a first cell C1 in the biological sample from passing and allows a second cell C2 having a smaller diameter than that of the first cell C1 to pass; and a filtration cylinder for separating, in the storage container and via the filter, the liquid L into a first liquid L1 mainly including the first cell C1 and a second liquid L2 mainly including the second cell C2. A measurement target cell filtered by the filter among other cells can be easily collected.
Abstract:
A testing container is described having a vessel with a first end, a second end, and a sidewall extending between the first end and the second end. The first end forms an opening into the vessel. The sidewall has one or more protrusions extending inwardly therefrom. The one or more protrusions form a gap having a width in a range between 2-4 mm, and the one or more protrusions have sufficient strength to withstand lateral pressure of a swab positioned in the gap relative to the one or more protrusions and to remove a head of the swab.
Abstract:
Embodiments of the invention relate to a syringeless filter device compressor for compressing one or more syringeless filter devices. Such syringeless filter devices are typically compressed entirely by hand; however, this may be uncomfortable and/or dangerous for the operator. In embodiments of the present invention, there is provided an apparatus comprising a holder for holding a plurality of syringeless filter devices in a two-dimensional array, and a compressor device. The compressor includes a pusher which can be moved by an actuator to compress the filtration devices held in the two-dimensional array. These features enable a compact compressor device for compressing syringeless filter devices, without the operator being in contact with the syringeless filter device during the compression process.
Abstract:
An automated filter changing system comprises a rotatable filter dispensing assembly and a filter clamping assembly. The filter dispensing device receives filter storage magazines in which a plurality of filters are initially stored in the form of connected stacks. The filter dispensing assembly includes a filter separating device having a stationary portion. The filter separating device separates one or more stacks of filters into discrete filter units, such that individual filters are transported sequentially from the filter dispensing device. The filter clamping assembly operates in conjunction with the filter dispensing device to receive one or more individual filter units dispensed therefrom, and provides one or more coupling sites which can fluidly communicate with one or more fluid lines. The filter clamping device couples unused filters to fittings associated with the fluid lines by applying an evenly distributed force to the filters.
Abstract:
An automated liquid level sensing system for use in an automated, continuous, and random access analytical system is disclosed. A pipette probe is positioned above, and lowered into, a liquid sample container which contains the liquid to be detected. The probe is energized by a near radio-frequency (RF) signal source. A receiving antenna is positioned below the sample container, and is oriented so that very little signal is detected from the probe while the probe is in air. When the probe contacts liquid in the sample container, the electromagnetic field of the RF signal is increased and reoriented toward the receiving antenna. An autozero circuit maintains a near-zero output from the receiving antenna when slow changes in signal level occur due to changes in probe position or other environmental factors. The autozero circuit allows the sudden increase in signal amplitude, due to liquid contact, to pass to a receiver. A shield-driven triax cable connects the autozero circuit to the receiver, and significantly reduces the normal capacitance of the cable, enabling the signal change to be more easily detected.