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公开(公告)号:US12130222B2
公开(公告)日:2024-10-29
申请号:US17839565
申请日:2022-06-14
Applicant: PARTICLE MEASURING SYSTEMS, INC.
Inventor: Edward Yates , Cary Hertert , Brian A. Knollenberg
CPC classification number: G01N15/10 , G01N15/14 , G01N2015/1024 , G01N2015/1486
Abstract: Disclosed is a method for detecting and/or growing particles, comprising controlling the surface area exposed to the saturator region by monitoring at least one of a depth of the working liquid on the saturator surface, the surface area exposed to the saturator region, or a volume of the working liquid on the saturator surface. Also disclosed is an apparatus or system for detecting and/or growing particles, comprising a fluidics system configured to control the surface area exposed to the saturator region by monitoring at least one of a depth of the working liquid on the saturator surface, the surface area exposed to the saturator region, or a volume of the working liquid on the saturator surface. Certain aspects do not employ one or more porous structures for vapor generation, nor a separate carrier fluid flow or inlet comprising a carrier fluid and vaporized working liquid for combining with the sample flow in the saturator region.
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公开(公告)号:US20240344962A1
公开(公告)日:2024-10-17
申请号:US18580046
申请日:2021-07-20
Applicant: ATTEN2 ADVANCED MONITORING TECHNOLOGIES S.L.
Inventor: Iñaki BRAVO IMAZ , Aitor ARNAIZ IRIGARAY
IPC: G01N15/1434 , G01N11/00 , G01N15/14
CPC classification number: G01N15/1434 , G01N11/00 , G01N2015/1486
Abstract: A system for inspecting a fluid includes a lighting system for illuminating a fluid under inspection in an image detection area; an image capture system for capturing a sequence of images of the fluid in the image detection area; a magnetic component for generating a magnetic field towards the image fluid under inspection, the magnetic component having at least one coil for generating a magnetic field, whereby ferromagnetic particles in the fluid under inspection are prevented from reaching the image detection area; wherein the image capture system is configured to capture an image of the fluid in the image detection area before the magnetic field is applied and an image of the fluid in the image detection area after the magnetic field is applied, free of ferromagnetic particles; and a processing component configured to compare the images of the fluid under inspection and count the ferromagnetic particles in the fluid.
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公开(公告)号:US12112648B2
公开(公告)日:2024-10-08
申请号:US17184142
申请日:2021-02-24
Applicant: Honeywell International Inc.
Inventor: Lee R. Wienkes
IPC: G08G5/00 , B64D43/00 , G01N15/0205 , G01N15/14
CPC classification number: G08G5/0091 , B64D43/00 , G01N15/0205 , G01N15/14 , G01N2015/0238 , G01N2015/1486
Abstract: A system for determining a vehicle operating state is provided. The system includes at least two particle detectors, a controller and a memory. A sample volume used by each particle detector of the at least two particle detectors configured to be collected in a different location relative to the vehicle than another sample volume used by another particle detector of the at least two particle detectors and at least one sample volume is configured to be collected in an environment where particles are disturbed by the vehicle. The controller is configured to determine at least one operating state of the vehicle based at least in part on a comparison of output signals of the at least two particle detectors. The at least one memory is used to store at least operating instructions implemented by the controller in determining the at least one operating state of the vehicle.
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公开(公告)号:US12105010B2
公开(公告)日:2024-10-01
申请号:US18373487
申请日:2023-09-27
Applicant: Becton, Dickinson and Company
Inventor: Jonathan Lin , Keegan Owsley , Matthew Bahr
IPC: G01N15/14 , G01N15/1429 , G01N15/1434 , G01N15/149 , G01N15/1404
CPC classification number: G01N15/1459 , G01N15/1425 , G01N15/1429 , G01N15/1434 , G01N2015/1402 , G01N2015/142 , G01N2015/1486 , G01N15/149
Abstract: Aspects of the present disclosure include methods for characterizing particles of a sample in a flow stream. Methods according to certain embodiments include generating frequency-encoded fluorescence data from a particle of a sample in a flow stream; and calculating phase-corrected spatial data of the particle by performing a transform of the frequency-encoded fluorescence data with a phase correction component. In certain embodiments, methods include generating an image of the particle in the flow stream based on the phase-corrected spatial data. Systems having a processor with memory operably coupled to the processor having instructions stored thereon, which when executed by the processor, cause the processor to calculate phase-corrected spatial data from frequency-encoded fluorescence data of a particle a flow stream are also described. Integrated circuit devices (e.g., field programmable gate arrays) having programming for practicing the subject methods are also provided.
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公开(公告)号:US12078645B2
公开(公告)日:2024-09-03
申请号:US16073742
申请日:2017-01-25
Applicant: Hôpitaux Universitaires de Strasbourg , Diagnostica Stago
Inventor: Julie Helms , Florence Toti , Laure Stiel , Laurent Mauvieux , Ferhat Meziani
CPC classification number: G01N33/86 , G01N15/14 , G01N33/5005 , G01N33/6893 , G01N2015/1486 , G01N2333/70503 , G01N2333/70596 , G01N2800/226 , G01N2800/26 , G01N2800/50 , G01N2800/52
Abstract: A method and kit for-, in particular, the medical and veterinary field, predicts and/or detects disseminated intravascular coagulation (DIC) in a biological sample.
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公开(公告)号:US12046333B2
公开(公告)日:2024-07-23
申请号:US17986726
申请日:2022-11-14
Inventor: Bo Ye , Changsong Hu , Huan Qi , Wenbo Zheng
CPC classification number: G16B45/00 , G01N1/14 , G01N1/31 , G01N15/1459 , G01N33/5094 , G01N2001/1418 , G01N2015/016 , G01N2015/018 , G01N2015/1486
Abstract: A blood cell analysis method and a blood cell analyzer are provided. In the method and analyzer, characteristic information of white blood cell fragments is obtained based on side scattered light information and fluorescence information, characteristic information of platelets is obtained based on forward scattered light information and fluorescence information and then a count value for the platelets is acquired based on the characteristic information of the platelets and the characteristic information of the white blood cell fragments. The present invention can avoid the influence of the white blood cell fragments on the platelet counting, thereby ensuring the accuracy of the platelet counting without increasing costs.
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公开(公告)号:US12044603B2
公开(公告)日:2024-07-23
申请号:US17752823
申请日:2022-05-24
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding
IPC: G01N1/28 , B01L3/00 , G01N1/30 , G01N15/01 , G01N15/14 , G01N21/64 , G01N21/65 , G01N21/69 , G01N21/76 , G01N33/487 , G01N33/49 , G01N33/543 , G01N35/00
CPC classification number: G01N1/2813 , B01L3/5055 , G01N1/30 , G01N15/1484 , G01N21/6452 , G01N21/69 , G01N21/76 , G01N33/487 , G01N33/49 , G01N33/543 , G01N33/54366 , G01N35/00029 , G01N35/00871 , B01L2300/0809 , B01L2300/123 , B01L2400/0481 , G01N2015/012 , G01N2015/016 , G01N2015/018 , G01N2015/1486 , G01N2021/6482 , G01N21/658
Abstract: The present invention is related to the field of bio/chemical sampling, sensing, assays and applications. Particularly, the present invention is related to how to make the sampling/sensing/assay become simple to use, fast to results, highly sensitive, easy to use, using tiny sample volume (e.g. 0.5 uL or less), operated by a person without any professionals, reading by mobile-phone, or low cost, or a combination of them.
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公开(公告)号:US12025550B2
公开(公告)日:2024-07-02
申请号:US17172041
申请日:2021-02-09
Applicant: CytoChip Inc.
Inventor: Wendian Shi , Yuzhe Ding
IPC: G01N15/1404 , A61B5/00 , A61B10/00 , B01F31/00 , B01F31/65 , B01F33/30 , B01L3/00 , G01N15/01 , G01N15/06 , G01N15/075 , G01N15/10 , G01N15/14 , G01N33/50 , G01N33/569
CPC classification number: G01N15/1404 , A61B10/0096 , B01F31/00 , B01F31/65 , B01F33/30 , B01F33/30351 , B01L3/5027 , B01L3/502715 , B01L3/502723 , B01L3/50273 , B01L3/502738 , B01L3/502761 , G01N15/06 , G01N15/1484 , G01N33/5094 , G01N33/56972 , A61B5/0071 , B01L2200/143 , B01L2300/0645 , B01L2300/0654 , B01L2300/0681 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/0877 , B01L2300/0887 , B01L2300/161 , B01L2300/168 , B01L2400/0406 , B01L2400/0409 , B01L2400/0457 , B01L2400/0487 , B01L2400/0688 , B01L2400/088 , G01N2015/012 , G01N2015/016 , G01N2015/018 , G01N15/075 , G01N2015/1006 , G01N2015/1486
Abstract: The disclosure relates to devices and methods for analyzing particles in a sample. In various embodiments, the present disclosure provides devices and methods for cytometry and additional analysis. In various embodiments, the present disclosure provides a cartridge device and a reader instrument device, wherein the reader instrument device receives, operates, and/or actuates the cartridge device. In various embodiments, the present disclosure provides a method of using a device as disclosed herein for analyzing particles in a sample.
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公开(公告)号:US11971341B2
公开(公告)日:2024-04-30
申请号:US16196479
申请日:2018-11-20
Applicant: MINITÜB GMBH
Inventor: Georg Wippenbeck , Christian Simmet
IPC: B01L3/00 , C12Q1/06 , G01N15/06 , G01N15/10 , G01N15/14 , G01N15/1404 , G01N21/03 , G02B21/34 , G02B21/16
CPC classification number: G01N15/1404 , B01L3/5027 , C12Q1/06 , G01N15/06 , G02B21/34 , B01L2200/021 , B01L2200/026 , B01L2200/14 , G01N2015/0693 , G01N2015/1006 , G01N2015/1486 , G01N2201/0662 , G02B21/16
Abstract: The present invention relates to a method for analyzing samples comprising spermatozoa, said method comprising the use of a flow-through counting compartment, wherein the time period between the end of loading and closing is carried out in a controlled and specified time period. The present invention further relates to a counting compartment or chamber suitable for said method and to a counting device comprising said counting compartment.
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公开(公告)号:US11946848B2
公开(公告)日:2024-04-02
申请号:US17984116
申请日:2022-11-09
Applicant: Iris International, Inc.
Inventor: Thomas H. Adams , Bart J. Wanders , John Roche , Harvey L. Kasdan
IPC: G01N15/14 , G01N1/30 , G01N15/00 , G01N15/06 , G01N15/10 , G01N15/1404 , G01N15/1429 , G01N15/1434 , G01N21/05 , G01N21/53 , G01N33/49 , G01N33/50 , G01N33/80 , G02B7/28 , G02B7/36 , G02B21/24 , G06T7/00 , G01N15/1409
CPC classification number: G01N15/1404 , G01N1/30 , G01N15/06 , G01N15/1429 , G01N15/1434 , G01N15/1436 , G01N15/1459 , G01N15/1463 , G01N15/1468 , G01N15/147 , G01N15/1475 , G01N21/53 , G01N33/49 , G01N33/4915 , G01N33/5091 , G01N33/5094 , G01N33/80 , G02B7/36 , G01N2015/0065 , G01N2015/1037 , G01N2015/1411 , G01N2015/1413 , G01N2015/144 , G01N2015/1452 , G01N2015/1481 , G01N2015/1486 , G01N2021/058 , G02B7/28 , G02B21/244 , G06T7/0012 , G06T2207/10148
Abstract: For analyzing a sample containing particles of at least two categories, such as a sample containing blood cells, a particle counter subject to a detection limit is coupled with an analyzer capable of discerning particle number ratios, such as a visual analyzer, and a processor. A first category of particles can be present beyond detection range limits while a second category of particles is present within respective detection range limits. The concentration of the second category of particles is determined by the particle counter. A ratio of counts of the first category to the second category is determined on the analyzer. The concentration of particles in the first category is calculated on the processor based on the ratio and the count or concentration of particles in the second category.
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