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    MICROPARTICLE SORTING DEVICE AND MICROPARTICLE SORTING METHOD
    1.
    发明公开
    MICROPARTICLE SORTING DEVICE AND MICROPARTICLE SORTING METHOD 审中-公开

    公开(公告)号：US20230296488A1

    公开(公告)日：2023-09-21

    申请号：US18016510

    申请日：2021-04-20

    申请人： Sony Group Corporation

    发明人： Masahide Furukawa

    IPC分类号： G01N15/14 ,  B01L3/00

    CPC分类号： G01N15/1404 ,  B01L3/502761 ,  G01N2015/142 ,  G01N2015/149 ,  G01N2015/1411 ,  B01L2200/0652 ,  B01L2400/0433 ,  B01L2300/088

    摘要： To provide a technique capable of forming stable droplets.
    There is provided a microparticle sorting device including a microchip including a main flow path through which a liquid containing a microparticle flows, a sheath liquid flow path that communicates with the main flow path and through which a sheath liquid flows, and a sheath liquid introduction portion that introduces the sheath liquid, in which the sheath liquid flowing through the sheath liquid introduction portion is vibrated. Furthermore, there is also provided a microparticle sorting method including, in a microchip including at least a main flow path through which a liquid containing a microparticle flows, a sheath liquid flow path that communicates with the main flow path and through which a sheath liquid flows, and a sheath liquid introduction portion that introduces the sheath liquid, vibrating the sheath liquid flowing through the sheath liquid introduction portion.

    HEMATOLOGY SYSTEMS AND METHODS
    2.
    发明申请
    HEMATOLOGY SYSTEMS AND METHODS 有权
    HEMATOLOGY系统和方法

    公开(公告)号：US20160041083A1

    公开(公告)日：2016-02-11

    申请号：US14775448

    申请日：2014-03-18

    申请人： IRIS INTERNATIONAL, INC.

    发明人： Bart J. WANDERS ,  Gregory A. FARRELL ,  Thomas H. ADAMS ,  Warren GRONER ,  Xiaodong ZHAO ,  Brett JORDAN ,  Jack CREMINS ,  Carol QUON

    IPC分类号： G01N15/14 ,  G01N33/49

    CPC分类号： G01N15/1404 ,  G01N1/30 ,  G01N15/1434 ,  G01N15/1463 ,  G01N15/1468 ,  G01N15/147 ,  G01N15/1475 ,  G01N21/53 ,  G01N33/49 ,  G01N33/4915 ,  G01N33/5091 ,  G01N33/5094 ,  G01N33/80 ,  G01N2015/0065 ,  G01N2015/1037 ,  G01N2015/1411 ,  G01N2015/1413 ,  G01N2015/1452 ,  G01N2015/1486 ,  G01N2021/058

    摘要： Aspects and embodiments of the instant disclosure provide a particle and/or intracellular organelle alignment agent for a particle analyzer used to analyze particles contained in a sample. An exemplary particle and/or intracellular organelle alignment agent includes an aqueous solution, a viscosity modifier, and/or a buffer. Embodiments also encompass systems, compositions, and methods for analyzing a sample containing particles. Particles such as blood cells can be categorized and counted by a digital image processor. A digital microscope camera can be directed, for example using certain focusing techniques, into a flowcell defining a symmetrically narrowing flowpath in which the sample stream flows in a ribbon flattened by flow and viscosity parameters between layers of sheath fluid. Blood cell images can be collected and analyzed using dynamic range extension processes and systems.

    摘要翻译： 本公开的方面和实施方案提供用于分析样品中包含的颗粒的颗粒分析仪的颗粒和/或细胞内细胞器取向剂。 示例性的颗粒和/或细胞内细胞器取向剂包括水溶液，粘度调节剂和/或缓冲液。 实施方案还包括用于分析含有颗粒的样品的系统，组合物和方法。 可以通过数字图像处理器对诸如血细胞的颗粒进行分类和计数。 数字显微镜照相机可以例如使用某些聚焦技术引导到限定对称变窄的流动路径的流动池中，其中样品流在由鞘液层之间的流动和粘度参数平坦化的带中流动。 可以使用动态范围扩展过程和系统收集和分析血细胞图像。

    Sheath flow forming device and sample analyzer provided with same
    6.
    发明授权
    Sheath flow forming device and sample analyzer provided with same 有权
    护套流动成型装置和样品分析仪

    公开(公告)号：US07628956B2

    公开(公告)日：2009-12-08

    申请号：US10946061

    申请日：2004-09-22

    申请人： Katsuhiko Jindo

    发明人： Katsuhiko Jindo

    IPC分类号： G01N21/00

    CPC分类号： G01N15/1404 ,  F04B11/0075 ,  F04B53/16 ,  G01N2015/1409 ,  G01N2015/1411

    摘要： The sheath flow forming device includes: a container for storing sample fluid and having a supply port for supplying the sample fluid; a second container for storing sheath fluid and having a supply port for supplying the sheath fluid; a flow cell having a sample fluid inlet for receiving sample fluid supplied from the supply port of the first container, a sheath fluid inlet for receiving the sheath fluid from the supply port of the second container, and an outlet for discharging the mixture of the sheath fluid and the sample fluid; a first pump for supplying a sheath fluid to the sheath fluid inlet; a second pump for suctioning fluid within the flow cell through the outlet of the flow cell; and a first drive source for driving the first pump and second pump.

    摘要翻译： 鞘流形成装置包括：用于储存样品流体并具有用于供给样品流体的供给口的容器; 用于储存鞘液的第二容器，并具有用于供给鞘液的供给口; 流动池，其具有用于接收从第一容器的供给口供给的样品流体的样品流体入口，用于从第二容器的供给口接收鞘液的鞘液入口，以及用于将鞘的混合物排出的出口 流体和样品液; 用于将鞘液供给到鞘液入口的第一泵; 第二泵，用于通过流动池的出口抽吸流动池内的流体; 以及用于驱动第一泵和第二泵的第一驱动源。

    Sheath liquid for particle analyzer
    7.
    发明申请
    Sheath liquid for particle analyzer 有权
    用于颗粒分析仪的护套液体

    公开(公告)号：US20070177146A1

    公开(公告)日：2007-08-02

    申请号：US11699551

    申请日：2007-01-30

    申请人： Yukie Fujimoto

    发明人： Yukie Fujimoto

    IPC分类号： G01N21/00

    CPC分类号： G01N15/1404 ,  G01N2015/1411 ,  Y10T436/10 ,  Y10T436/101666 ,  Y10T436/108331 ,  Y10T436/25

    摘要： A sheath liquid for a particle analyzer being used to analyze particles contained in a sample is described. The sheath liquid comprises water and a refractive-index adjustment agent comprising glycerols and/or sulfate.A method for producing the sheath liquid and a method for analyzing particles using the sheath liquid are also described.

    摘要翻译： 描述了用于分析样品中包含的颗粒的用于粒子分析仪的鞘液。 鞘液包含水和包含甘油和/或硫酸盐的折射率调节剂。 还描述了用于制备鞘液的方法和使用鞘液分析颗粒的方法。