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    CO-PLANAR MICRO-IMPEDANCE CYTOMETRY DEVICE
    5.
    发明申请
    CO-PLANAR MICRO-IMPEDANCE CYTOMETRY DEVICE 审中-公开

    公开(公告)号：US20190137380A1

    公开(公告)日：2019-05-09

    申请号：US15802596

    申请日：2017-11-03

    申请人： Sharp Life Science (EU) Limited

    发明人： Christopher James Brown ,  Pamela Ann Dothie

    IPC分类号： G01N15/14 ,  G01N15/12 ,  G01N33/483 ,  G01N15/02

    CPC分类号： G01N15/1404 ,  G01N15/02 ,  G01N15/1031 ,  G01N15/1209 ,  G01N33/4836 ,  G01N2015/1006 ,  G01N2015/1409 ,  G01N2015/1413

    摘要： An impedance cytometry device is described along with methods of accurately measuring particle size of particles contained in a fluid that is passed through the impedance cytometry device. The impedance cytometry device includes a substrate, and an electrode arrangement deposited on the substrate in a co-planar fashion. The electrode arrangement includes a drive electrode and a plurality of measurement electrodes located in a same plane as the drive electrode. The plurality of measurement electrodes includes at least two pairs of measurement sub-electrodes, each pair of measurement sub-electrodes including a first measurement sub-electrode positioned adjacent to the drive electrode, and a second measurement sub-electrode separated from the drive electrode by a respective first measurement sub-electrode. The impedance cytometry device may be incorporated into a substrate assembly of an electrowetting on dielectric (EWOD) device, such as in a substrate assembly containing electrowetting drive electrodes or a common reference electrode, or into a microfluidic blood counter device.

    Multiple-Spot Time-Sequential Cytometry
    6.
    发明申请
    Multiple-Spot Time-Sequential Cytometry 审中-公开

    公开(公告)号：US20190049356A1

    公开(公告)日：2019-02-14

    申请号：US16045094

    申请日：2018-07-25

    申请人： CAPTL LLC

    发明人： Masanobu Yamamoto ,  J. Paul Robinson

    IPC分类号： G01N15/14 ,  G01N15/10

    CPC分类号： G01N15/1427 ,  G01N15/1404 ,  G01N15/1434 ,  G01N15/147 ,  G01N15/1475 ,  G01N2015/1006 ,  G01N2015/1409 ,  G01N2015/1413 ,  G01N2015/144 ,  G01N2015/1452

    摘要： An image flow cytometer for observing a microparticulate sample includes a flow chamber having a flow channel that permits the microparticulate sample to travel in a flow direction. An irradiation system scans an irradiation spot across a sensing area of the flow channel in a scan direction different from the flow direction. A detection system detects resultant light from the sensing area and provides a detection signal. An alignment system alters a location of the sensing area with respect to the flow chamber. A control unit causes the irradiation system to scan the irradiation spot during a first measurement interval and operates the alignment system to translate the location of the sensing area along the flow direction. The flow chamber can be mounted to a movable stage in some examples, and the alignment system can move the flow chamber substantially opposite the flow direction using the stage.