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公开(公告)号：US20240219307A1
公开(公告)日：2024-07-04
申请号：US18429280
申请日：2024-01-31
发明人： Charles M. CLINTON , Eli N. GLEZER , Sharon WEST , George SIGAL , Carl STEVENS , Michael L. VOCK
CPC分类号： G01N21/76 , G01N21/69 , G01N35/0092 , G01N35/028 , G01N2035/00524 , G01N2035/0425 , G01N35/1079 , Y10T436/114165
摘要： We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
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公开(公告)号：US11940385B2
公开(公告)日：2024-03-26
申请号：US16270062
申请日：2019-02-07
发明人： Charles M. Clinton , Eli N. Glezer , Sharon West , George Sigal , Carl Stevens , Michael L. Vock
CPC分类号： G01N21/76 , G01N21/69 , G01N35/0092 , G01N35/028 , G01N2035/00524 , G01N2035/0425 , G01N35/1079 , Y10T436/114165
摘要： We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
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公开(公告)号：US20190011370A1
公开(公告)日：2019-01-10
申请号：US16025482
申请日：2018-07-02
申请人： ARKRAY, Inc.
发明人： Kojiro Honma , Kentaro Kiriyama , Hirofumi Yamada
CPC分类号： G01N21/73 , G01J3/28 , G01J3/443 , G01J2003/2866 , G01N1/28 , G01N21/67 , G01N21/69 , G01N2001/2893
摘要： The disclosure provides plasma spectroscopy analysis methods using a preparatory process of adding a control metal species that is different from an analyte metal species to a sample so as to have a known concentration; a concentration process of introducing the sample to a measurement container, and applying an electric current across a pair of electrodes disposed in the measurement container to concentrate the analyte metal species and the control metal species in the sample in a vicinity of at least one of the electrodes; a detection process; a correction process; and a quantification process.
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公开(公告)号：US20180275058A1
公开(公告)日：2018-09-27
申请号：US15756938
申请日：2016-09-02
发明人： Eric STERN , Aleksandar VACIC , Nathan B. PURMORT
CPC分类号： G01N21/6428 , B01L3/5027 , B01L3/502715 , B01L2200/0605 , B01L2300/0681 , B01L2300/0816 , B01L2300/0867 , B01L2300/0887 , B01L2400/0487 , B01L2400/06 , B01L2400/0688 , B82Y15/00 , G01J3/44 , G01J3/4406 , G01N21/03 , G01N21/645 , G01N21/6452 , G01N21/6489 , G01N21/69 , G01N21/76 , G01N2021/0321 , G01N2021/0328 , G01N2021/0346 , G01N2021/6482 , G01N2201/0245
摘要： In some aspects, reader systems for optically detecting binding agents or analyte complexes in a sample as a result of performing biochemical assays can include: a housing defining a positioning receptacle to receive the sample; an excitation source to generate incident light directed at the sample; at least one solid-state photomultiplier detector configured to: i) receive a light emitted by at least one label associated with the binding agents and/or analyte complexes within the sample; and ii) produce a signal in response to receiving the light emitted by the at least one label or substrate solution that is physically or chemically modified by the said label, the at least one detector being connected to integrated signal processing electronics to process the signal; and a user interface in communication with the signal processing electronics for conveying one or more results of the one or more biochemical as says.
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公开(公告)号：US20180230608A1
公开(公告)日：2018-08-16
申请号：US15896734
申请日：2018-02-14
申请人： ARKRAY, Inc.
发明人： Tokuo Kasai
摘要： An electrolysis device comprising a cell containing a solution, a pair of electrodes installed in the cell, and a voltage application device connected to the pair of electrodes. One electrode of the pair of electrodes is a small electrode, and another electrode of the pair of electroeds is a large electrode. An area of a liquid-contacting portion of the small electrode with the solution is smaller than an area of a liquid-contacting portion of the large electrode with the solution. In a state in which the solution is contained in the cell, only the solution is present between the liquid-contacting portion of the small electrode and a liquid surface of the solution vertically above the liquid-contacting portion of the small electrode.
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公开(公告)号：US20180164191A1
公开(公告)日：2018-06-14
申请号：US15837190
申请日：2017-12-11
发明人： Dries Beyens
CPC分类号： G01N1/125 , G01N21/01 , G01N21/03 , G01N21/69 , G01N33/205 , G01N2001/1068 , G01N2021/0193 , G01N2021/695
摘要： A sample chamber assembly for molten metal comprises a cover plate and a housing. A first face of the housing has a depression in direct flow communication with a first opening formed at the immersion end of the housing. The cover plate and the housing are assembled together along a first plane to form a sample cavity including the depression. An analysis surface of a solidified metal sample lies in the first plane. The sample cavity and the first opening are aligned along a common longitudinal axis. The first opening is spaced apart from the first plane. A ratio of the thermal diffusivities of the solidified metal sample and the housing material is between 0.1 and 0.5. The housing is inseparable from the solidified metal sample. A portion of the housing is directly adjacent to the solidified metal sample and lies in the first plane.
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公开(公告)号：US09891165B2
公开(公告)日：2018-02-13
申请号：US15255036
申请日：2016-09-01
发明人： Brooks Hart Pate , Kevin K. Lehmann
IPC分类号： G01J3/30 , G01N21/3586 , G01N22/00 , G01N21/31 , G01N21/62 , G01N21/69 , G01J3/44 , G01N21/67
CPC分类号： G01N21/3586 , G01J3/10 , G01J3/4338 , G01J3/44 , G01N21/31 , G01N21/62 , G01N21/67 , G01N21/69 , G01N22/00 , H01S3/0057
摘要： A pulse train comprising chirped pulses can be used to excite a sample, such as for spectroscopic analysis. The respective chirped pulses can include a frequency sweep to establish a first frequency-domain comb. A width of frequency-domain comb peaks can be established at least in part by a total duration of the pulse train, and a bandwidth of the first frequency-domain comb can be determined at least in part by a bandwidth of the frequency sweep of the respective chirped pulses. A free-space or enclosed sample interaction region can be used.
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公开(公告)号：US09505619B2
公开(公告)日：2016-11-29
申请号：US11385277
申请日：2006-03-20
申请人： Richard J. Massey , Mark T. Martin , Liwen Dong , Ming Lu , Alan Fischer , Fabian Jameison , Pam Liang , Robert Hoch , Jonathan K. Leland
发明人： Richard J. Massey , Mark T. Martin , Liwen Dong , Ming Lu , Alan Fischer , Fabian Jameison , Pam Liang , Robert Hoch , Jonathan K. Leland
IPC分类号： G01N33/573 , C12Q1/32 , C01B31/02 , B82Y30/00 , B82Y40/00 , C07K17/06 , D01F9/12 , D01F11/14 , G01N33/543 , G01N33/58 , H01M4/60 , G01N21/69 , G01N21/76 , G01N30/88 , G11C13/02
CPC分类号： C01B31/0213 , B82Y30/00 , B82Y40/00 , C01B32/152 , C01B32/174 , C01B2202/34 , C01B2202/36 , C07K17/06 , D01F9/12 , D01F11/14 , G01N21/69 , G01N21/76 , G01N33/54373 , G01N33/5438 , G01N33/582 , G01N2030/8863 , G11C13/025 , H01M4/60 , Y10S435/968 , Y10S436/805 , Y10S436/806 , Y10S977/737 , Y10S977/742
摘要： Graphitic nanotubes, which include tubular fullerenes (commonly called “buckytubes”) and fibrils, which are functionalized by chemical substitution, are used as solid supports in electrogenerated chemiluminescence assays. The graphitic nanotubes are chemically modified with functional group biomolecules prior to use in an assay. Association of electrochemiluminescent ruthenium complexes with the functional group biomolecule-modified nanotubes permits detection of molecules including nucleic acids, antigens, enzymes, and enzyme substrates by multiple formats.
摘要翻译： 石墨纳米管，其包括通过化学取代官能化的管状富勒烯（通常称为“buckytubes”）和原纤维，被用作电致化学发光测定中的固体支持物。 石墨纳米管在用于测定之前用官能团生物分子进行化学修饰。 电化学发光钌络合物与官能团生物分子修饰的纳米管的关联允许通过多种形式检测包括核酸，抗原，酶和酶底物的分子。
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公开(公告)号：US09046462B2
公开(公告)日：2015-06-02
申请号：US13704483
申请日：2011-06-17
申请人： Brooks Hart Pate , Kevin K. Lehmann
发明人： Brooks Hart Pate , Kevin K. Lehmann
IPC分类号： G01J3/30 , G01N22/00 , G01N21/3586 , H01S3/00
CPC分类号： G01N21/3586 , G01J3/10 , G01J3/4338 , G01J3/44 , G01N21/31 , G01N21/62 , G01N21/67 , G01N21/69 , G01N22/00 , H01S3/0057
摘要： A pulse train comprising chirped pulses of electromagnetic energy can be used to excite a sample, such as for spectroscopic analysis. The respective chirped pulses can include a frequency sweep across a first specified bandwidth during a respective chirped pulse duration, the respective chirped pulse duration establishing a first frequency-domain comb peak separation. A width of a frequency-domain comb peak can be established at least in part by a total duration of the pulse train, and a bandwidth of the first frequency-domain comb can be determined at least in part by the first specified bandwidth of the frequency sweep of the respective chirped pulses.
摘要翻译： 可以使用包括电磁能的啁啾脉冲的脉冲串来激发样品，例如用于光谱分析。 相应的啁啾脉冲可以包括在相应的啁啾脉冲持续时间期间穿过第一指定带宽的频率扫描，相应的啁啾脉冲持续时间建立第一频域梳状峰值间隔。 可以至少部分地由脉冲序列的总持续时间来建立频域梳状峰值的宽度，并且可以至少部分地通过频率的第一指定带宽来确定第一频域梳状的带宽 扫描各个啁啾脉冲。
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公开(公告)号：US20110020178A1
公开(公告)日：2011-01-27
申请号：US12796692
申请日：2010-06-09
申请人： Charles M. Clinton , Eli N. Glezer , Sharon West , George Sigal , Carl Stevens , Michael L. Vock
发明人： Charles M. Clinton , Eli N. Glezer , Sharon West , George Sigal , Carl Stevens , Michael L. Vock
IPC分类号： G01N21/76
CPC分类号： G01N21/76 , G01N21/69 , G01N35/0092 , G01N35/028 , G01N35/1079 , G01N2035/0425 , Y10T436/114165
摘要： We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
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