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    Method of detecting a risk of cancer
    4.
    发明授权
    Method of detecting a risk of cancer 有权
    检测癌症风险的方法

    公开(公告)号：US09400284B2

    公开(公告)日：2016-07-26

    申请号：US14289207

    申请日：2014-05-28

    申请人： Anthony Sabato Vigliotti ,  Salvatore Anthony Vigliotti

    发明人： Anthony Sabato Vigliotti ,  Salvatore Anthony Vigliotti

    IPC分类号： G01N33/84 ,  G01N33/48 ,  G01N33/52

    CPC分类号： G01N33/84 ,  G01N33/48 ,  G01N33/52 ,  G01N33/57488 ,  G01N2800/50 ,  Y10T436/172307 ,  Y10T436/25 ,  Y10T436/25625

    摘要： A method of detecting a subject's cancer risk is provided. The method includes: gathering a sample of the subject's body water content via saliva; determining a ratio of cyanide within the subject's body water content and tissue saturation via saliva; providing a threshold cyanide ratio; comparing the ratio of cyanide within the subject's body water content and tissue saturation to the threshold cyanide ratio; and determining the patient's cancer risk based on the comparison of the ratio of cyanide within the subject's body water content to the threshold cyanide ratio.

    摘要翻译： 提供了检测受试者的癌症风险的方法。 该方法包括：通过唾液收集受试者体内水分的样本; 通过唾液确定受试者体内水含量和组织饱和度中氰化物的比例; 提供阈值氰化物比例; 比较受试者身体含水量和组织饱和度之间的氰化物与氰化物的比例; 并且基于对象体内含水量中氰化物的比例与阈值氰化物比的比较来确定患者的癌症风险。

    Method and system for determining a biological response of a target to a soluble candidate substance
    6.
    发明申请
    Method and system for determining a biological response of a target to a soluble candidate substance 有权
    用于确定靶向可溶性候选物质的生物反应的方法和系统

    公开(公告)号：US20160011180A1

    公开(公告)日：2016-01-14

    申请号：US14771437

    申请日：2014-03-04

    申请人： F. HOFFMANN-LA ROCHE AG

    发明人： Michael Werner ,  Rainer E. Martin ,  Remo Anton Hochstrasser

    IPC分类号： G01N33/536 ,  G01N21/64 ,  C12Q1/25

    CPC分类号： G01N33/536 ,  B01L3/502776 ,  B01L2200/0694 ,  B01L2300/0816 ,  B01L2300/0883 ,  B01L2400/0472 ,  B01L2400/0487 ,  C12Q1/25 ,  G01N21/6428 ,  G01N21/6486 ,  G01N33/558 ,  G01N2021/6439 ,  Y10T436/25625 ,  Y10T436/2575

    摘要： A method for determining a biological response of a target (41, 42) to a soluble candidate substance comprises the steps: introducing a soluble candidate substance into a laminar flow of a buffer liquid (2) to form a candidate substance solute (3) having an initial concentration profile (31); dispersing the initial concentration profile (31) to form a dispersed concentration profile (32); directing the dispersed concentration profile (32) into a detection channel (12) to form a final symmetrical concentration profile (33) therein; introducing a target into the detection channel (12) to obtain a combined concentration profile comprising a constant target concentration profile overlying the final symmetrical concentration profile (33); holding in the detection channel (12) at least one half of the combined concentration profile; and optically scanning the combined concentration profile to detect an optical signal representative of the biological response of the target to the soluble candidate substance.

    摘要翻译： 用于确定靶（41,42）对可溶性候选物质的生物反应的方法包括以下步骤：将可溶性候选物质引入缓冲液体（2）的层流中以形成候选物质溶质（3），其具有 初始浓度分布（31）; 分散初始浓度分布（31）以形成分散浓度分布（32）; 将分散的浓度分布（32）引导到检测通道（12）中以在其中形成最终对称的浓度分布（33）; 将目标引入检测通道（12）以获得组合浓度分布，其包括覆盖最终对称浓度分布（33）的恒定目标浓度分布; 在所述检测通道（12）中保持所述组合浓度分布的至少一半; 并且光学扫描组合的浓度分布，以检测表示靶向可溶性候选物质的生物反应的光学信号。

    Method for controlling the sensitivity and response point of chemical test kits for metals in paint and other media
    8.
    发明授权
    Method for controlling the sensitivity and response point of chemical test kits for metals in paint and other media 有权
    控制涂料和其他介质中金属化学试剂盒的灵敏度和响应点的方法

    公开(公告)号：US09128075B2

    公开(公告)日：2015-09-08

    申请号：US13539317

    申请日：2012-06-30

    申请人： Frederic G Dewalt ,  David C. Cox

    发明人： Frederic G Dewalt ,  David C. Cox

    IPC分类号： G01N31/22 ,  G01N33/84 ,  G01N1/38 ,  G01N1/28

    CPC分类号： G01N31/22 ,  G01N1/38 ,  G01N2001/2866 ,  Y10T436/25625

    摘要： A method of changing the response level for any chemical test kits designed for the determination of a metal or compound (such as lead) in paint and other media is disclosed. The invention solves two common problems that exist with using chemical test kits for the detection of lead in paint or other coatings and media: (1) conversion of the paint sample into particles small enough to dissolve the metal in the sample; and, (2) controlling the amount of (paint) sample that gets exposed to the chemicals. This is accomplished by using a coffee grinder or equivalent tool plus a solid (food) product to break up the paint sample into small particles and at the same time dilute the concentration of the metal, while in solid form, down to a level that results in obtaining a positive response at the desired concentration.

    摘要翻译： 公开了改变用于测定涂料和其它介质中的金属或化合物（例如铅）的任何化学试剂盒的响应水平的方法。 本发明解决了使用化学试剂盒检测涂料或其他涂料和介质中铅的两个常见问题：（1）将涂料样品转化成足够小的颗粒以溶解样品中的金属; 和（2）控制暴露于化学品的（油漆）样品的量。 这是通过使用咖啡研磨机或等效工具加上固体（食品）产品来完成的，以将油漆样品分解成小颗粒，同时将固体形式的金属浓度降至一定水平 在获得所需浓度的阳性反应。