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公开(公告)号：US20240335160A1
公开(公告)日：2024-10-10
申请号：US18750225
申请日：2024-06-21
发明人： Luke Ashdown , Daniel Trenton
IPC分类号： A61B5/00 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/145 , A61B10/00 , A63B24/00 , A63B71/06 , G01N33/48 , G01N33/50 , G06F7/06 , G09B5/06 , G09B19/00 , G16H10/60 , G16H20/30 , G16H20/40 , G16H20/60 , G16H40/67 , G16H50/20 , G16H70/60
CPC分类号： A61B5/41 , A61B5/0022 , A61B5/02055 , A61B5/4857 , A61B5/486 , A61B5/7275 , A61B10/0051 , A63B24/0075 , A63B71/0622 , G01N33/48 , G01N33/50 , G06F7/06 , G09B5/06 , G09B19/0092 , G16H20/30 , G16H20/40 , G16H50/20 , G16H70/60 , A61B5/021 , A61B5/02405 , A61B5/145 , A63B2071/0625 , G01N2800/24 , G01N2800/56 , G16H10/60 , G16H20/60 , G16H40/67
摘要： A system and method for determining the immune status or immune cycle in a subject is provided. A sampling component for obtaining physiological data from the subject is provided together with a data storage component for storing the physiological data obtained from the subject. A processing component is provided to analyse the physiological data and thereby determine the immune status or periodicity of the immune cycle and the immune cycle of the subject. An output component for outputting the immune status or periodicity of the immune cycle, and the immune cycle of the subject and/or the future status or immune cycle of the subject is provided.
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公开(公告)号：US12055537B2
公开(公告)日：2024-08-06
申请号：US16771927
申请日：2018-12-13
发明人： Malene Møller Jørgensen , Rikke Bæk
CPC分类号： G01N33/5002 , G01N33/48 , G01N33/68
摘要： A method is provided, which comprises providing a dried body fluid card sample, extracting body fluid from said dried body fluid card sample, and detecting gene products associated with extracellular vesicles. An application of the method is also applied for diagnosing and/or prognosing a clinical condition, where gene products associated with a population of extracellular vesicles and gene products associated with the clinical condition are detected.
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公开(公告)号：US12053292B2
公开(公告)日：2024-08-06
申请号：US15533365
申请日：2015-12-03
发明人： Luke Ashdown , Daniel Trenton
IPC分类号： A61B5/00 , A61B5/0205 , A61B10/00 , A63B24/00 , A63B71/06 , G01N33/48 , G01N33/50 , G06F7/06 , G09B5/06 , G09B19/00 , G16H10/60 , G16H20/30 , G16H20/40 , G16H20/60 , G16H40/67 , G16H50/20 , G16H70/60 , A61B5/021 , A61B5/024 , A61B5/145
CPC分类号： A61B5/41 , A61B5/0022 , A61B5/02055 , A61B5/4857 , A61B5/486 , A61B5/7275 , A61B10/0051 , A63B24/0075 , A63B71/0622 , G01N33/48 , G01N33/50 , G06F7/06 , G09B5/06 , G09B19/0092 , G16H20/30 , G16H20/40 , G16H50/20 , G16H70/60 , A61B5/021 , A61B5/02405 , A61B5/145 , A63B2071/0625 , G01N2800/24 , G01N2800/56 , G16H10/60 , G16H20/60 , G16H40/67
摘要： A system and method for determining the immune status or immune cycle in a subject is provided. A sampling component for obtaining physiological data from the subject is provided together with a data storage component for storing the physiological data obtained from the subject. A processing component is provided to analyse the physiological data and thereby determine the immune status or periodicity of the immune cycle and the immune cycle of the subject. An output component for outputting the immune status or periodicity of the immune cycle, and the immune cycle of the subject and/or the future status or immune cycle of the subject is provided.
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公开(公告)号：US12029764B2
公开(公告)日：2024-07-09
申请号：US16618148
申请日：2018-05-29
CPC分类号： A61K35/38 , A61L27/3633 , A61L27/3813 , A61L27/54 , A61L2300/434 , A61L2430/28 , G01N33/48
摘要： A method for obtaining epithelial organoids is provided. In one embodiment, the method comprises culturing one or more epithelial ducts, epithelial duct fragments and/or epithelial stem cells isolated therefrom in contact with an extracellular matrix in the presence of a basal medium, wherein the medium is free of FGF and/or nicotinamide. Organoids obtained by the methods described herein, and uses thereof, are also provided.
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公开(公告)号：US11975326B2
公开(公告)日：2024-05-07
申请号：US16146792
申请日：2018-09-28
发明人： Mariko Matsunaga , Ken Tsukii , Kenichi Kimura , Toru Takahashi , Jie Xu
CPC分类号： B01L3/502753 , B01L3/502715 , B01L3/50855 , C12M23/12 , C12M23/20 , C12M23/22 , C12M33/04 , C12M41/36 , G01N33/48 , G01N33/5005 , B01L2300/161 , B01L2300/168
摘要： A cell accommodating chip capable of accommodating a plurality of cells includes a substrate composed of a light-transmitting material, and a plurality of wells on at least one of main faces of the substrate, the plurality of wells being capable of accommodating cells. A surface of the cell accommodating chip including the plurality of wells has a low cell adhesion property, and affinity to a specific binding material having affinity to a produced substance produced by a cell accommodated in one of the wells and/or a released substance released by the cell.
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公开(公告)号：US20240133862A1
公开(公告)日：2024-04-25
申请号：US18472451
申请日：2023-09-21
发明人： Qingli LI
IPC分类号： A61B90/00 , A61B5/107 , G01N33/48 , G06T7/00 , G06V30/224
CPC分类号： A61B90/00 , A61B5/1075 , A61B5/1079 , G01N33/48 , G06T7/0012 , G06V30/2247 , A61B2562/0247 , G06T2207/10036 , G06T2207/30024
摘要： A multi-dimensional data acquisition and analysis system for placenta tissue is provided, including a preparation area, a sampling area, a tension cable, a mobile platform, a tray, a mobile cabin door, a cabin door motor, a motor, a motor controller, binocular vision cameras, a laser point cloud detector, a hyperspectral camera, an ultrasonic ranging, a lifting motor, a lifting guide rail, ring light sources, an infrared sensor, a two-dimensional code area and a two-dimensional code identification camera. The technical scheme of the disclosure is adopted to solve the problem of lack of effective technical means for placenta detection at present.
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公开(公告)号：US11921110B2
公开(公告)日：2024-03-05
申请号：US18085462
申请日：2022-12-20
发明人： Jaume Esteve Tintó , José Antonio Plaza Plaza , Marta Duch Llobera , Núria Torras Andrés , María Luisa Pérez García , Juan Pablo Agusil Antonoff
CPC分类号： G01N33/5432 , B01J19/00 , B01J19/0046 , B82Y30/00 , G01N33/48 , G01N33/582 , G03F7/0002 , B01J2219/00756 , B82Y40/00
摘要： A method for controlled production of an array of planar microparticles with the multiplexing of molecules on the surface thereof, intended to function as molecular sensors and/or actuators and a matrix (array) of microparticles, the surface thereof being printed with all of the molecular components required to provide the surface with functionality. Different molecular elements are multiplexed on the surface of each particle while they are supported on a substrate by means of a structural foot engraved below the particle. These microparticles can be released mechanically from the support on which they are produced using a controlled mechanical rupture method which is not chemically aggressive and therefore does not affect the molecules previously printed on the surface. The array and the particles contained therein offer great versatility in both chemical and/or biological applications.
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公开(公告)号：US11921101B2
公开(公告)日：2024-03-05
申请号：US17648887
申请日：2022-01-25
申请人： Bonraybio Co., Ltd.
发明人： Cheng-Teng Hsu , Chih-Pin Chang , Kuang-Li Huang , Yu-Chiao Chi , Chia-Wei Chang , Chiung-Han Wang
IPC分类号： G01N33/48 , G01N1/28 , G01N15/10 , G01N15/14 , G01N21/17 , G06T7/00 , G06T7/11 , G06T7/80 , G06T7/90 , H04N23/58 , H04N23/67 , G01N15/00 , H04N23/57
CPC分类号： G01N33/48 , G01N1/2806 , G01N15/1012 , G01N15/1429 , G01N15/1463 , G01N21/17 , G06T7/0014 , G06T7/11 , G06T7/80 , G06T7/90 , H04N23/58 , H04N23/67 , G01N2015/0065 , G01N2015/1075 , G01N2015/1486 , G01N2021/177 , G06T2207/30168 , H04N23/57
摘要： Disclosed are calibration techniques that can be implemented by a device that conducts biological tests. In certain embodiments, the device for testing a biological specimen includes a receiving mechanism to receive a carrier, a camera module arranged to capture imagery of the carrier, and a processor. Some examples of the processor can detect a calibration mode trigger. In calibration mode, the processor can divide the captured imagery into segments and selectively perform one or more calibration procedures for each segment. Then, the processor records a calibration result for each segment.
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公开(公告)号：US11899007B2
公开(公告)日：2024-02-13
申请号：US17648901
申请日：2022-01-25
申请人： Bonraybio Co., Ltd.
发明人： Cheng-Teng Hsu , Chih-Pin Chang , Kuang-Li Huang , Yu-Chiao Chi , Chia-Wei Chang , Chiung-Han Wang
IPC分类号： G01N33/48 , G01N1/28 , G01N21/17 , G06T7/80 , G06T7/11 , G06T7/90 , G01N15/10 , G01N15/14 , G06T7/00 , H04N23/58 , H04N23/67 , G01N15/00 , H04N23/57
CPC分类号： G01N33/48 , G01N1/2806 , G01N15/1012 , G01N15/1429 , G01N15/1463 , G01N21/17 , G06T7/0014 , G06T7/11 , G06T7/80 , G06T7/90 , H04N23/58 , H04N23/67 , G01N2015/0065 , G01N2015/1075 , G01N2015/1486 , G01N2021/177 , G06T2207/30168 , H04N23/57
摘要： Disclosed are verification techniques that can be implemented by a device that conducts biological tests to verify that the specimen holding area carries a valid biological specimen. In certain embodiments, the testing device includes a receiving mechanism to receive a carrier, and the carrier includes a holding area that is to carry or to be exposed to a biological specimen. The device can also include a camera module arranged to capture imagery of the carrier, and a processor. In some examples, the processor can capture the imagery of the carrier and identify a visual cue on the carrier. Then, the processor can verify, based on a manner of how the visual cue is displayed in the captured imagery, whether the holding area carries a valid biological specimen.
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公开(公告)号：US11852632B2
公开(公告)日：2023-12-26
申请号：US17964758
申请日：2022-10-12
申请人： MIE UNIVERSITY
发明人： Akira Mizoguchi , Koji Tanaka , Naoyuki Katayama , Tetsuya Nosaka , Kyosuke Tanaka , Shujie Wang , Aika Kaito , Kousyoku Sai , Kazushi Kimura
IPC分类号： G01N35/00 , G01N33/574 , G01N1/30 , G01N1/31 , G01N21/78 , G01N33/48 , G01N21/64 , A61B1/00 , G01N33/483 , C12M1/00 , G01N33/50
CPC分类号： G01N33/57496 , A61B1/00 , G01N1/30 , G01N1/31 , G01N21/64 , G01N21/78 , G01N33/48 , C12M41/06 , G01N33/4833 , G01N33/50 , G01N33/574 , G01N2001/302
摘要： A cancer test device (1) is provided with: an application unit (40) for applying a staining agent (45), which can selectively stain a product of a cancer-relating gene in a living cell a chromatic color, onto a group of living cells; an imaging unit (10) for imaging the group of living cells having the staining agent (45) applied thereto; and a determination unit (52) for determining the level of malignancy of cancerization of the group of living cells on the basis of the state of the stained expression pattern of the cancer-relating gene in the group of living cells in an image obtained by the aforementioned imaging.
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