公开(公告)号：US09970923B2

公开(公告)日：2018-05-15

申请号：US15251370

申请日：2016-08-30

Applicant: Church & Dwight Co., Inc.

Inventor： Andy Sturman ,  Benedict Zin ,  Albert Nazareth ,  Henry Bell

IPC: G01N21/03 ,  G01N33/487 ,  G01N21/84 ,  G01N21/17 ,  G01N33/493 ,  G01N33/62 ,  G01N33/68 ,  G01N33/76

CPC classification number: G01N33/48792 ,  G01N21/17 ,  G01N21/8483 ,  G01N33/48785 ,  G01N33/493 ,  G01N33/62 ,  G01N33/689 ,  G01N33/76 ,  G01N2201/062 ,  G01N2201/12 ,  G01N2333/59

Abstract: An improved electronic diagnostic device for detecting the presence of an analyte in a fluid sample comprises a casing having a display, a test strip mounted in the casing, a processor mounted in the casing, and a first sensor mounted in the casing and operatively coupled to the processor. The processor is configured to receive a signal from the first sensor when the device is exposed to ambient light thereby causing the device to become activated. The device includes a light shield that exerts pressure across a width of the test strip to prevent fluid channeling along the length of the test strip. The processor is configured to present an early positive test result reading when a measured value exceeds a predetermined early reading threshold value at any time after a predetermined early testing time period.

公开(公告)号：US20170199181A1

公开(公告)日：2017-07-13

申请号：US15472553

申请日：2017-03-29

Applicant: Abbott Point of Care Inc.

Inventor： Katrina Di Tullio ,  G. Bruce Collier ,  John Lewis Emerson Campbell

IPC: G01N33/543 ,  G01N33/68 ,  C12Q1/58 ,  G01N33/62

CPC classification number: G01N33/54306 ,  C12Q1/58 ,  G01N33/5438 ,  G01N33/54393 ,  G01N33/62 ,  G01N33/6893 ,  G01N2800/347

Abstract: The present invention is directed to methods and devices for amending undiluted and partially diluted urine samples in a manner suitable for performing immunoassays for target analytes, for example NGAL. Generally, the urine sample is treated with reagents including at least one of buffer materials, water soluble proteins, urease, and other interferent mitigants. These reagents control the pH of the urine sample in a manner suitable for immuno-binding reactions and ameliorate interferences, particularly during the detection step.

公开(公告)号：US20170049673A1

公开(公告)日：2017-02-23

申请号：US15254426

申请日：2016-09-01

Applicant: The Procter & Gamble Company

Inventor： Karl Shiqing WEI

IPC: A61K8/31 ,  A61K8/96 ,  G01N33/68 ,  A61Q19/10

CPC classification number: A61K8/31 ,  A61K8/03 ,  A61K8/96 ,  A61K49/0006 ,  A61K2800/87 ,  A61Q19/10 ,  G01N33/5088 ,  G01N33/62 ,  G01N33/6812 ,  G01N33/6827 ,  G01N33/6869 ,  G01N33/6881 ,  G01N33/92 ,  G01N2333/4742 ,  G01N2333/545 ,  G01N2500/04 ,  G01N2800/20 ,  G06Q30/0201

Abstract: A skin treatment regimen for delivery of a rinse-off personal skin care composition is provided. The rinse-off personal skin care composition includes varying ratios of a lathering agent to a hydrophobic benefit agent. The rinse-off personal skin care composition can be applied to skin of a user in phases over and/or in a treatment cycle. Each of the phases of the treatment cycle can include a ratio of the varying ratios that can be different such as higher or lower than a ratio of adjacent phase.

Abstract translation: 提供用于递送漂洗个人护肤组合物的皮肤治疗方案。 漂洗的个人护肤组合物包括起泡剂与疏水有益剂的不同比例。 漂洗的个人护肤组合物可以在治疗周期和/或治疗周期中分阶段地应用于使用者的皮肤。 处理循环的每个阶段可以包括可以不同的变化比例的比例，例如高于或低于相邻相的比率。

公开(公告)号：US09523671B2

公开(公告)日：2016-12-20

申请号：US14774651

申请日：2014-03-13

Applicant: Nestec S.A.

Inventor： Francois-Pierre Martin ,  Sebastiano Collino ,  Ivan Montoliu Roura

IPC: G01N33/493 ,  G01N33/62 ,  A61K31/702 ,  G01N33/50 ,  G01N33/68 ,  G01N24/08

CPC classification number: G01N33/493 ,  A61K31/702 ,  C12Q2565/633 ,  G01N24/08 ,  G01N33/50 ,  G01N33/62 ,  G01N33/6893 ,  G01N2570/00 ,  G01N2800/02 ,  G01N2800/044 ,  G01N2800/50 ,  G01N2800/52 ,  G01N2800/60 ,  G01N2800/70

Abstract: The present invention relates generally to the field of nutrition and health. In particular, the present invention relates to indoxyl sulfate as a biomarker in urine of the efficacy of prebiotics for the prevention of diet induced weight gain.

Abstract translation: 本发明一般涉及营养和健康领域。 特别地，本发明涉及作为益生元的功效的尿中生物标志物的吲哚硫酸盐作为预防饮食诱导的体重增加。

公开(公告)号：US09316648B2

公开(公告)日：2016-04-19

申请号：US14817642

申请日：2015-08-04

Applicant: Spectrum Laboratories, LLC

Inventor： James Matthew Stephens

IPC: G01N33/493 ,  G01N33/70 ,  G01N33/62

CPC classification number: G01N33/62 ,  G01N33/493 ,  G01N33/70 ,  G01N2496/80 ,  Y10T436/10 ,  Y10T436/147777 ,  Y10T436/171538

Abstract: A synthetic urine solution and method of its manufacture are disclosed. The solution includes water having a pH between about 3 and about 10. The solution further includes creatinine, a means for removing bacteria from the solution so as to control or eliminate sepsis of the urine solution, preferably through the use of a biocide, and a urea-based compound. The solution exhibits a specific gravity of from 1.005 g/cm3 to 1.025 g/cm3. Additional compounds may also be included to further enhance the aesthetics or apparent authenticity of the synthetic urine.

公开(公告)号：US20160033473A1

公开(公告)日：2016-02-04

申请号：US14774651

申请日：2014-03-13

Applicant: NESTEC S.A.

Inventor： Francois-Pierre Martin ,  Sebastiano Collino ,  Ivan Montoliu Roura

IPC: G01N33/493 ,  G01N33/62 ,  A61K31/702

CPC classification number: G01N33/493 ,  A61K31/702 ,  C12Q2565/633 ,  G01N24/08 ,  G01N33/50 ,  G01N33/62 ,  G01N33/6893 ,  G01N2570/00 ,  G01N2800/02 ,  G01N2800/044 ,  G01N2800/50 ,  G01N2800/52 ,  G01N2800/60 ,  G01N2800/70

Abstract: The present invention relates generally to the field of nutrition and health. In particular, the present invention relates to indoxyl sulfate as a biomarker in urine of the efficacy of prebiotics for the prevention of diet induced weight gain.

Abstract translation: 本发明一般涉及营养和健康领域。 特别地，本发明涉及作为益生元的功效的尿中生物标志物的吲哚硫酸盐作为预防饮食诱导的体重增加。

公开(公告)号：US20160003823A1

公开(公告)日：2016-01-07

申请号：US14829572

申请日：2015-08-18

Applicant: Theranos, Inc.

Inventor： Elizabeth A. Holmes

IPC: G01N33/569

CPC classification number: G01N35/0092 ,  B01L3/021 ,  B01L3/5082 ,  B01L3/50855 ,  B01L7/52 ,  B01L9/06 ,  B01L9/52 ,  B01L9/543 ,  B01L2300/1827 ,  B01L2300/1855 ,  C12Q1/42 ,  C12Q1/52 ,  C12Q1/6883 ,  C12Q1/70 ,  G01N15/1475 ,  G01N21/25 ,  G01N21/27 ,  G01N33/5005 ,  G01N33/54306 ,  G01N33/54313 ,  G01N33/54366 ,  G01N33/56983 ,  G01N33/62 ,  G01N33/6827 ,  G01N33/80 ,  G01N33/92 ,  G01N35/00 ,  G01N35/00029 ,  G01N35/00069 ,  G01N35/00623 ,  G01N35/00871 ,  G01N35/026 ,  G01N35/04 ,  G01N35/10 ,  G01N35/1009 ,  G01N35/1011 ,  G01N35/1065 ,  G01N35/1072 ,  G01N2015/0073 ,  G01N2015/008 ,  G01N2015/1006 ,  G01N2015/1486 ,  G01N2035/00138 ,  G01N2035/00148 ,  G01N2035/00237 ,  G01N2035/00306 ,  G01N2035/00326 ,  G01N2035/00356 ,  G01N2035/00366 ,  G01N2035/00425 ,  G01N2035/00435 ,  G01N2035/00495 ,  G01N2035/00633 ,  G01N2035/0449 ,  G01N2035/0474 ,  G01N2035/0486 ,  G01N2035/0491 ,  G01N2035/0493 ,  G01N2035/0494 ,  G01N2201/024 ,  G01N2201/04 ,  G01N2201/12 ,  Y10T436/111666 ,  Y10T436/113332

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

公开(公告)号：US20150368717A1

公开(公告)日：2015-12-24

申请号：US14789930

申请日：2015-07-01

Applicant: Theranos, Inc.

Inventor： Elizabeth A. Holmes ,  Sunny Balwani ,  Michael Chen ,  John K. Frankovich ,  Gary Frenzel ,  Surekha Gangakhedkar ,  Samartha Anekal ,  Adrit Lath ,  Alexander Loo ,  Chinmay Pangarkar ,  Paul Patel ,  Joy Roy ,  Timothy Smith ,  Daniel Young ,  Ian Gibbons

IPC: C12Q1/68 ,  B01L7/00 ,  C12Q1/70

CPC classification number: G01N35/0092 ,  B01L3/021 ,  B01L3/5082 ,  B01L3/50855 ,  B01L7/52 ,  B01L9/06 ,  B01L9/52 ,  B01L9/543 ,  B01L2300/1827 ,  B01L2300/1855 ,  C12Q1/42 ,  C12Q1/52 ,  C12Q1/6883 ,  C12Q1/70 ,  G01N15/1475 ,  G01N21/25 ,  G01N21/27 ,  G01N33/5005 ,  G01N33/54306 ,  G01N33/54313 ,  G01N33/54366 ,  G01N33/56983 ,  G01N33/62 ,  G01N33/6827 ,  G01N33/80 ,  G01N33/92 ,  G01N35/00 ,  G01N35/00029 ,  G01N35/00069 ,  G01N35/00623 ,  G01N35/00871 ,  G01N35/026 ,  G01N35/04 ,  G01N35/10 ,  G01N35/1009 ,  G01N35/1011 ,  G01N35/1065 ,  G01N35/1072 ,  G01N2015/0073 ,  G01N2015/008 ,  G01N2015/1006 ,  G01N2015/1486 ,  G01N2035/00138 ,  G01N2035/00148 ,  G01N2035/00237 ,  G01N2035/00306 ,  G01N2035/00326 ,  G01N2035/00356 ,  G01N2035/00366 ,  G01N2035/00425 ,  G01N2035/00435 ,  G01N2035/00495 ,  G01N2035/00633 ,  G01N2035/0449 ,  G01N2035/0474 ,  G01N2035/0486 ,  G01N2035/0491 ,  G01N2035/0493 ,  G01N2035/0494 ,  G01N2201/024 ,  G01N2201/04 ,  G01N2201/12 ,  Y10T436/111666 ,  Y10T436/113332

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

公开(公告)号：US20150338428A1

公开(公告)日：2015-11-26

申请号：US14789920

申请日：2015-07-01

Applicant: Theranos, Inc.

Inventor： Elizabeth A. Holmes ,  Sunny Balwani ,  Michael Chen ,  John K. Frankovich ,  Gary Frenzel ,  Surekha Gangakhedkar ,  Samartha Anekal ,  Adrit Lath ,  Alexander Loo ,  Chinmay Pangarkar ,  Paul Patel ,  Joy Roy ,  Timothy Smith ,  Daniel Young ,  Ian Gibbons

IPC: G01N35/02 ,  G01N35/10

CPC classification number: G01N35/0092 ,  B01L3/021 ,  B01L3/5082 ,  B01L3/50855 ,  B01L7/52 ,  B01L9/06 ,  B01L9/52 ,  B01L9/543 ,  B01L2300/1827 ,  B01L2300/1855 ,  C12Q1/42 ,  C12Q1/52 ,  C12Q1/6883 ,  C12Q1/70 ,  G01N15/1475 ,  G01N21/25 ,  G01N21/27 ,  G01N33/5005 ,  G01N33/54306 ,  G01N33/54313 ,  G01N33/54366 ,  G01N33/56983 ,  G01N33/62 ,  G01N33/6827 ,  G01N33/80 ,  G01N33/92 ,  G01N35/00 ,  G01N35/00029 ,  G01N35/00069 ,  G01N35/00623 ,  G01N35/00871 ,  G01N35/026 ,  G01N35/04 ,  G01N35/10 ,  G01N35/1009 ,  G01N35/1011 ,  G01N35/1065 ,  G01N35/1072 ,  G01N2015/0073 ,  G01N2015/008 ,  G01N2015/1006 ,  G01N2015/1486 ,  G01N2035/00138 ,  G01N2035/00148 ,  G01N2035/00237 ,  G01N2035/00306 ,  G01N2035/00326 ,  G01N2035/00356 ,  G01N2035/00366 ,  G01N2035/00425 ,  G01N2035/00435 ,  G01N2035/00495 ,  G01N2035/00633 ,  G01N2035/0449 ,  G01N2035/0474 ,  G01N2035/0486 ,  G01N2035/0491 ,  G01N2035/0493 ,  G01N2035/0494 ,  G01N2201/024 ,  G01N2201/04 ,  G01N2201/12 ,  Y10T436/111666 ,  Y10T436/113332

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

Abstract translation: 提供系统和方法用于样品处理。 可以提供能够接收样品并执行样品制备，样品测定和检测步骤中的一种或多种的装置。 该装置可能能够进行多个测定。 该装置可以包括一个或多个可以执行样品制备，样品测定和检测步骤中的一个或多个的模块。 该装置可以能够使用小体积的样品来执行步骤。

公开(公告)号：US20150017068A1

公开(公告)日：2015-01-15

申请号：US14453918

申请日：2014-08-07

Applicant: Church & Dwight, Co., Inc.

Inventor： Andy Sturman ,  Benedict Zin ,  Albert Nazareth ,  Henry Bell

IPC: G01N33/68 ,  G01N33/76 ,  G01N33/62 ,  G01N33/493 ,  G01N21/17

CPC classification number: G01N33/48792 ,  G01N21/17 ,  G01N21/8483 ,  G01N33/48785 ,  G01N33/493 ,  G01N33/62 ,  G01N33/689 ,  G01N33/76 ,  G01N2201/062 ,  G01N2201/12 ,  G01N2333/59

Abstract: An improved electronic diagnostic device for detecting the presence of an analyte in a fluid sample comprises a casing having a display, a test strip mounted in the casing, a processor mounted in the casing, and a first sensor mounted in the casing and operatively coupled to the processor. The processor is configured to receive a signal from the first sensor when the device is exposed to ambient light thereby causing the device to become activated. The device includes a light shield that exerts pressure across a width of the test strip to prevent fluid channeling along the length of the test strip. The processor is configured to present an early positive test result reading when a measured value exceeds a predetermined early reading threshold value at any time after a predetermined early testing time period.

Abstract translation: 用于检测流体样品中分析物的存在的改进的电子诊断装置包括具有显示器的壳体，安装在壳体中的测试条，安装在壳体中的处理器，以及安装在壳体中并可操作地耦合到 处理器。 该处理器被配置为当该设备暴露于环境光从而导致该设备被激活时从第一传感器接收信号。 该装置包括遮光板，其在测试条的宽度上施加压力，以防止沿着测试条的长度的流体通道。 处理器被配置为当在预定的早期测试时间段之后的任何时间测量值超过预定的早期读取阈值时呈现早期的正测试结果读数。