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公开(公告)号：US20240361243A1
公开(公告)日：2024-10-31
申请号：US18626595
申请日：2024-04-04
发明人： Craig Prater
IPC分类号： G01N21/64
CPC分类号： G01N21/6456 , G01N21/6486 , G01N2201/062 , G01N2201/0636
摘要： Methods and systems described herein detect autofluorescence of a sample. These methods and systems obviate the need for addition of fluorophores to samples to create IR absorption
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2.发明授权公开(公告)号：US12092568B2
公开(公告)日：2024-09-17
申请号：US17049833
申请日：2019-04-12
发明人： Herfried Huemer , Arnold Bartel , Stefan Gulo , Patrick Kraus-Füreder , Robert Scholz-Mareich , Wolfgang Sprengers
CPC分类号： G01N21/31 , B01L3/5085 , G01N21/0303 , B01L2300/0654 , B01L2300/0829 , B01L2300/0832 , B01L2300/168 , G01N2021/0389 , G01N2201/062 , G01N2201/0633
摘要： Aspects of the present disclosure are directed to, for example, an optical measurement unit for obtaining measurement signals from liquid media which are present in cuvettes lined up next to one another. In one embodiment, the optical measurement unit includes a light-supplying unit for emitting an inlet radiation into the cuvettes, and a detection unit for detecting a measurement radiation exiting from the cuvettes and for converting the measurement radiation into an electrical measurement signal. In such an embodiment, the light-supplying unit has a plurality of LED light sources which emit in a spectrally different manner in the UV/VIS/NIR wavelength range, and wherein the detection unit includes at least one photodiode fixedly assigned to each cuvette of a cuvette array.
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公开(公告)号：US20240280472A1
公开(公告)日：2024-08-22
申请号：US18567941
申请日：2022-12-20
申请人： HemoCue AB
CPC分类号： G01N21/07 , G01N1/4077 , G01N21/31 , G01N33/491 , G06T7/0012 , G01N2001/4083 , G01N2201/062 , G06T2207/30024
摘要： Disclosed is a method for analyzing a blood sample. The method comprises arranging a cuvette comprising a sampling cavity and a sample analysis cavity on a rotatable member. The sampling cavity comprises a blood sample to be analyzed. The method comprises rotating the rotatable member at a first speed in a first rotation cycle for transfer of the blood sample from the sampling cavity to the sample analysis cavity. The method comprises rotating the rotatable member at a second speed in a second rotation cycle after the first rotation cycle for separating blood parts from plasma in the blood sample. The method comprises obtaining, using a photometer, during the second rotation cycle, second absorbance data indicative of absorbance in the plasma. The method comprises determining, based on the second absorbance data, a second blood parameter being a plasma free hemoglobin level of the blood sample. The method comprises providing an output indicative of the second blood parameter.
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公开(公告)号：US12066435B2
公开(公告)日：2024-08-20
申请号：US17383557
申请日：2021-07-23
申请人： Tianma Japan, Ltd.
IPC分类号： G01N33/543 , G01N21/64 , G02B21/16
CPC分类号： G01N33/54373 , G01N21/6428 , G01N21/6456 , G02B21/16 , G01N2021/6439 , G01N2201/062
摘要： A microdevice includes: a microchannel to which a measurement target solution containing a measurement target substance is introduced; an antibody being fixed to at least one sidewall surface of the microchannel and specifically binding to the measurement target substance; a fluorescence-labeled derivative being specifically bound to the antibody and being acquired by fluorescence-labeling the measurement target substance; and a light blocker blocking excitation light exciting fluorescent light radiated by the fluorescence-labeled derivative. The measurement target substance and the fluorescence-labeled derivative specifically bind to the antibody in a competitive manner, and the antibody is fixed to the sidewall surface of the microchannel in a state of specifically binding to the fluorescence-labeled derivative. The light blocker blocks the excitation light entering the fluorescence-labeled derivative specifically binding to the antibody.
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公开(公告)号：US12044630B2
公开(公告)日：2024-07-23
申请号：US17425307
申请日：2020-01-24
申请人： FASPAR S.p.A.
IPC分类号： G01N21/95 , B23Q17/09 , B23Q17/24 , G01N35/10 , G05B19/4065
CPC分类号： G01N21/95 , B23Q17/0995 , G01N35/10 , G05B19/4065 , B23Q17/2457 , G01N2201/021 , G01N2201/06113 , G01N2201/062 , G05B2219/37228 , G05B2219/37252 , G05B2219/37256 , G05B2219/45159 , G05B2219/50203
摘要： An automatic system for inspecting a cutting edge of a ring shaped blade. An example system includes one supporting and moving group rotatably mounted around one rotation axis and configured to support the ring shaped blade between at least one parking position and at least one reading position, one first emitting unit configured to emit at least one first inspection light beam, one second emitting unit configured to emit at least one second inspection light beam, one first detecting unit configured to detect a first light beam reflected from the ring shaped blade, and one second detecting unit configured to detect a second light beam reflected from the ring shaped blade, and one control and processing unit configured to receive an input and process at least one detection signal and output at least one quality index of the cutting edge of the ring shaped blade.
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公开(公告)号：US20240226875A1
公开(公告)日：2024-07-11
申请号：US18093466
申请日：2023-01-05
IPC分类号： B01L3/00 , G01N1/34 , G01N21/31 , G01N33/497
CPC分类号： B01L3/5023 , G01N1/34 , G01N21/31 , G01N33/497 , B01L2200/04 , B01L2200/16 , B01L2300/0654 , B01L2300/069 , G01N2033/4975 , G01N2201/062
摘要： The device, e.g., sensing cartridge, includes a first member, a second member coupled to the first member, a third member coupled to the second member, and a fourth member coupled to the third member. The first member is configured to separate plasma from whole blood, where the whole blood has a cellular component with a hydrodynamic diameter greater than 0.01 μm. The second member is configured to wick the plasma from the whole blood, where the second member acts on ammonium in the plasma to shift a phase equilibrium of the ammonium to ammonia gas. The third member is configured to prevent liquid permeation produced by the shift in the phase equilibrium of the ammonium to the ammonia gas. The fourth member is configured to act on the ammonia gas.
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公开(公告)号：US12030045B1
公开(公告)日：2024-07-09
申请号：US18093466
申请日：2023-01-05
IPC分类号： B01L3/00 , G01N1/34 , G01N21/31 , G01N33/497
CPC分类号： B01L3/5023 , G01N1/34 , G01N21/31 , G01N33/497 , B01L2200/04 , B01L2200/16 , B01L2300/0654 , B01L2300/069 , G01N33/4975 , G01N2201/062
摘要： The device, e.g., sensing cartridge, includes a first member, a second member coupled to the first member, a third member coupled to the second member, and a fourth member coupled to the third member. The first member is configured to separate plasma from whole blood, where the whole blood has a cellular component with a hydrodynamic diameter greater than 0.01 μm. The second member is configured to wick the plasma from the whole blood, where the second member acts on ammonium in the plasma to shift a phase equilibrium of the ammonium to ammonia gas. The third member is configured to prevent liquid permeation produced by the shift in the phase equilibrium of the ammonium to the ammonia gas. The fourth member is configured to act on the ammonia gas.
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公开(公告)号：US12013336B2
公开(公告)日：2024-06-18
申请号：US17738229
申请日：2022-05-06
申请人： OWS AGRI LIMITED
发明人： Dmitry Medvedev
CPC分类号： G01N21/33 , G01N21/255 , G01N2021/3181 , G01N2201/062
摘要： An apparatus includes an emitter, the emitter comprising an ultraviolet light emitting diode (UV-LED) and being disposed on a first end of a bounded volume suitable for holding a gas. The bounded volume can be a chamber, a room, or the like. The apparatus includes a detector, the detector comprising an ultraviolet light sensor (UV sensor) and being disposed on a second end of the bounded volume, the second end being opposite the first end, wherein the UV-LED comprises a point source, and wherein the emitter generates a parallel beam of light.
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公开(公告)号：US20240142376A1
公开(公告)日：2024-05-02
申请号：US17976161
申请日：2022-10-28
申请人： Seegene, Inc.
CPC分类号： G01N21/6428 , B01L3/5085 , B01L2300/0654 , G01N2201/062 , G01N2201/08
摘要： A light detection module according to the present disclosure includes an optical fiber mounting unit having a plurality of optical fibers disposed on one side thereof; a filter wheel spaced apart from the other side of the optical fiber mounting unit, the filter wheel having a plurality of filters; a drive unit for rotating the filter wheel; a light source unit for generating excitation light passing through the filter wheel; and a detection unit for detecting emission light passing through the filter wheel, wherein the plurality of filters includes a plurality of excitation light filters for filtering the excitation light and a plurality of emission light filters for filtering the emission light.
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公开(公告)号：US11953438B2
公开(公告)日：2024-04-09
申请号：US17843132
申请日：2022-06-17
申请人： STRECK LLC
发明人： Matthew R. Kreifels , Scott E. Whitney , Gregg Wilder , John Flanagan , James Dowling , Philip Hills , Michael Tilleman , Jeremie Jackson
CPC分类号： G01N21/6428 , C12Q1/686 , G01N21/645 , B01L7/52 , C12Q2561/113 , C12Q2563/107 , G01N2201/062 , G01N2201/068
摘要： An improved device and system for facilitating polymerase chain reaction including a light source, detector, waveguide, and filters that occupy minimal space and facilitate detection of stationary samples, reduced sample read time, and simultaneous reading of multiple light wavelengths.
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