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公开(公告)号:US11953438B2
公开(公告)日:2024-04-09
申请号:US17843132
申请日:2022-06-17
申请人: STRECK LLC
发明人: Matthew R. Kreifels , Scott E. Whitney , Gregg Wilder , John Flanagan , James Dowling , Philip Hills , Michael Tilleman , Jeremie Jackson
CPC分类号: G01N21/6428 , C12Q1/686 , G01N21/645 , B01L7/52 , C12Q2561/113 , C12Q2563/107 , G01N2201/062 , G01N2201/068
摘要: An improved device and system for facilitating polymerase chain reaction including a light source, detector, waveguide, and filters that occupy minimal space and facilitate detection of stationary samples, reduced sample read time, and simultaneous reading of multiple light wavelengths.
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公开(公告)号:US20240150850A1
公开(公告)日:2024-05-09
申请号:US18332590
申请日:2023-06-09
申请人: STRECK LLC , CREIGHTON UNIVERSITY
发明人: Maria Torres-Gonzalez , Nancy Hanson , Joel Lechner , Stephanie Cossette , Cathy Scheer , Matthew R. Kreifels , Stacey Morrow , Christopher Connelly , Laura R. Porter , Randy Fowler
IPC分类号: C12Q1/689 , C12Q1/6809 , C12Q1/6837 , C12Q1/6851 , C12Q1/686
CPC分类号: C12Q1/689 , C12Q1/6809 , C12Q1/6837 , C12Q1/6851 , C12Q1/686 , C12Q2545/101 , C12Q2600/106 , C12Q2600/16 , C12Q2600/166
摘要: Assays and methods for detecting resistance to beta-lactam antibiotics including detection of multiple β-lactamase family specific gene targets by polymerase chain reaction or microarray. One or more kits including primers and/or probes for identification of β-lactamase genes selected from the group consisting of one or more of the following: MOX-like, FOX-like, ACC-like, ACT/MIR-like, CMY-2-like, DHA-like, CTX-M-14-like, CTX-M-15-like, VIM-like, NDM-like, IMP-like, KPC-like, and OXA-48-like, OXA-51-like, OXA-143-like, OXA-58-like, OXA-23-like, OXA-24/40-like, TEM-like, and SHV-like. A kit may also include one or more primers and/or probes for the identification a non-beta lactamase gene family which confers antibiotic resistance, such as the MCR-1 gene.
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公开(公告)号:US11708614B2
公开(公告)日:2023-07-25
申请号:US16310074
申请日:2017-06-15
申请人: STRECK, LLC
发明人: Maria Torres-Gonzalez , Nancy Hanson , Joel Lechner , Stephanie Cossette , Cathy Scheer , Matthew R. Kreifels , Stacey Morrow , Christopher Connelly , Laura R. Porter , Randy Fowler
IPC分类号: C12Q1/689 , C12Q1/6809 , C12Q1/6837 , C12Q1/6851 , C12Q1/686
CPC分类号: C12Q1/689 , C12Q1/686 , C12Q1/6809 , C12Q1/6837 , C12Q1/6851 , C12Q2545/101 , C12Q2600/106 , C12Q2600/16 , C12Q2600/166
摘要: Assays and methods for detecting resistance to beta-lactam antibiotics including detection of multiple β-lactamase family specific gene targets by polymerase chain reaction or microarray. One or more kits including primers and/or probes for identification of β-lactamase genes selected from the group consisting of one or more of the following: MOX-like, FOX-like, ACC-like, ACT/MIR-like, CMY-2-like, DHA-like, CTX-M-14-like, CTX-M-15-like, VIM-like, NDM-like, IMP-like, KPC-like, and OXA-48-like, OXA-51-like, OXA-143-like, OXA-58-like, OXA-23-like, OXA-24/40-like, TEM-like, and SHV-like. A kit may also include one or more primers and/or probes for the identification a non-beta lactamase gene family which confers antibiotic resistance, such as the MCR-1 gene.
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