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公开(公告)号:US20240329169A1
公开(公告)日:2024-10-03
申请号:US18619464
申请日:2024-03-28
Applicant: Bruker BioSpin GmbH & Co. KG
Inventor: Rico SIMMLER , David OSEN , Daniel PODADERA SANCHEZ , Lukas BECKER
CPC classification number: G01R33/307 , G01R33/31 , G01N24/08
Abstract: An NMR method and apparatus uses a magic angle spinning (MAS) system with a MAS turbine having a MAS stator and a MAS rotor. At least two different gases or gas mixtures are fed to the stator through separate gas feeds, a first for the driving of the rotor and another, which is different from the first, for the bearing of the rotor. Respective pressures of the at least two different gases or gas mixtures are regulated separately, and the different gases or gas mixtures are prevented from mixing in the stator by means of a flushing seal through which they at least partially flow out of the stator. Conventional outflow nozzles do not need to be adapted, and the rotor can be operated at a high rotational frequency even at low pressures. The pressures remain stable so that no rotational oscillations occur during the NMR measurement.
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公开(公告)号:US20240319296A1
公开(公告)日:2024-09-26
申请号:US18276766
申请日:2022-01-26
Applicant: QUAD SYSTEMS AG
Inventor: Klemens KESSLER
Abstract: A compound consisting of the following components:
(A) 40-99.99 weight percent of at least one thermoplastic or thermoset polymer material selected as a halogenated or perhalogenated polymer;
(B) 0.01-60 weight percent of at least one inorganic particulate diamagnetic or paramagnetic material;
(C) 0-39.99 weight percent of at least one additive different from (B);
is proposed as a construction material in the detection-relevant spatial area (9) of a nuclear magnetic resonance device with a static magnetic field of at least 1 Tesla, and furthermore corresponding constructional elements, in particular sample holders, our proposed as well as method of manufacturing such constructional elements and uses of such constructional elements.-
3.
公开(公告)号:US20240296902A1
公开(公告)日:2024-09-05
申请号:US18598979
申请日:2024-03-07
Applicant: Liposcience, Inc.
Inventor: James D. Otvos
IPC: G16B5/00 , G01N15/01 , G01N15/06 , G01N24/08 , G01N33/483 , G01R33/465 , G16B40/00 , G16H10/40 , G16H20/00 , G16H50/20 , G16H50/30 , G16H50/50
CPC classification number: G16B5/00 , G01N15/0656 , G01N24/08 , G01N33/4833 , G01R33/465 , G16B40/00 , G16H10/40 , G16H20/00 , G16H50/20 , G16H50/30 , G16H50/50 , G01N15/01 , G01N2800/323 , G01N2800/324
Abstract: Methods, computer program products and apparatus determine a subject's risk of having or developing CHD using a calculated HDL particle risk number and/or a mathematical model of risk associated with HDL particles that adjusts concentrations of at least one of the subclasses of small, medium and large HDL particle measurements to reflect predicted CHD risk. A calculated LDL particle risk number may also be generated as well as a lipoprotein particle index derived from the ratio of RLDL/RHDL.
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4.
公开(公告)号:US20240248052A1
公开(公告)日:2024-07-25
申请号:US18595333
申请日:2024-03-04
Applicant: NEW YORK UNIVERSITY
Inventor: Alexej JERSCHOW , Andrew J. ILOTT , Mohaddese MOHAMMADI , Emilia SILLETTA , Konstantin ROMANENKO
CPC classification number: G01N24/08 , G01N24/10 , G01R31/3644 , G01R33/5602 , G01R33/5608
Abstract: A method of diagnosing a conducting structure includes providing the conducting structure in a magnetic field, immersing the conducting structure in a detection medium, or placing a detection medium in the vicinity of the conducting structure, exciting nuclear or electronic spins within the detection medium using a broad-band excitation pulse, receiving an NMR or ESR spectrum from the detection medium, obtaining a frequency distribution of the detection medium, and indirectly measuring internal characteristics of the conducting structure by characterizing frequency changes in the frequency distribution. Conducting structures are analyzed on the basis of changes in magnetic susceptibilities and internal electric current distributions, which may change over the course of a charging/discharging cycle, and a result of degradation and failure of the conducting structure. The conducting structure may be, for example, a battery, a capacitor, a supercapacitor, a fuel cell, or a catalyst material.
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5.
公开(公告)号:US20240161565A1
公开(公告)日:2024-05-16
申请号:US18552579
申请日:2022-03-22
Applicant: GIESECKE+DEVRIENT CURRENCY TECHNOLOGY GMBH
Inventor: Stephan HUBER
IPC: G07D7/04 , G01N24/08 , G01R33/345
CPC classification number: G07D7/04 , G01N24/08 , G01R33/3456
Abstract: A sensor element for testing a flat data carrier, in particular a banknote, has a spin resonance feature. The sensor element contains a magnetic core having an air gap, into which the flat data carrier can be inserted for testing, an element for generating a static magnetic flux in the air gap, and a resonator for exciting the spin resonance feature of the data carrier to be tested. The resonator is formed by a stripline resonator which is arranged in the air gap of the magnetic core and comprises a flat carrier having an upper side and a conducting structure which is arranged on the upper side of the carrier with a characteristic length.
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公开(公告)号:US20240125719A1
公开(公告)日:2024-04-18
申请号:US18471903
申请日:2023-09-21
Applicant: Liposcience, Inc.
Inventor: James D. Otvos , Elias J. Jeyarajah , Justyna E. Wolak-Dinsmore , Thomas M. O'Connell , Dennis W. Bennett , Steven P. Matyus , Stanley L. Hazen
IPC: G01N24/08 , G01N33/66 , G01R33/465 , G16B5/00 , G16B45/00
CPC classification number: G01N24/08 , G01N24/088 , G01N33/66 , G01R33/465 , G16B5/00 , G16B45/00 , G01N2800/323
Abstract: A defined peak region residing between about 3.2 and 3.4 ppm of a proton NMR spectrum of an in vitro biosample is electronically evaluated to determine a level of trimethylamine-N-oxide (“TMAO”). The biosample may be any suitable biosamples including human serum with a normal biologic range of between about 1-50 μM or urine with a normal biologic range of between about 0-1000 μM.
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公开(公告)号:US11946885B2
公开(公告)日:2024-04-02
申请号:US17842990
申请日:2022-06-17
Applicant: UNIVERSITY OF MARYLAND, BALTIMORE
Inventor: Yihua (Bruce) Yu , Marc Taraban
CPC classification number: G01N24/08 , C12N15/86 , G01R33/448 , C12N2750/14143
Abstract: A method of using the relaxation rate (R1 and/or R2) of solvent NMR signal to noninvasively assess whether viral capsids in a capsid preparation are full or empty, and the percentage of full capsids if the vial contains a mixture of full and empty capsids. The method can simply, rapidly, and non-invasively prove the safety and potency of the capsid preparation and thus whether the capsid preparation can be approved for clinical use, without requiring any sample preparation or reagent addition.
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公开(公告)号:US11942187B2
公开(公告)日:2024-03-26
申请号:US16673104
申请日:2019-11-04
Applicant: Liposcience, Inc.
Inventor: James D. Otvos
IPC: G01N33/48 , G01N15/06 , G01N24/08 , G01N33/483 , G01N33/50 , G01R33/465 , G16B5/00 , G16B40/00 , G16H10/40 , G16H20/00 , G16H50/20 , G16H50/30 , G16H50/50 , G01N15/00
CPC classification number: G16B5/00 , G01N15/0656 , G01N24/08 , G01N33/4833 , G01R33/465 , G16B40/00 , G16H10/40 , G16H20/00 , G16H50/20 , G16H50/30 , G16H50/50 , G01N2015/0065 , G01N2800/323 , G01N2800/324
Abstract: Methods, computer program products and apparatus determine a subject's risk of having or developing CHD using a calculated HDL particle risk number and/or a mathematical model of risk associated with HDL particles that adjusts concentrations of at least one of the subclasses of small, medium and large HDL particle measurements to reflect predicted CHD risk. A calculated LDL particle risk number may also be generated as well as a lipoprotein particle index derived from the ratio of RLDL/RHDL.
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公开(公告)号:US11940399B2
公开(公告)日:2024-03-26
申请号:US17829551
申请日:2022-06-01
Inventor: Ronald Walsworth , Nithya Arunkumar , Connor Hart , Dominik Bucher , David Glenn
CPC classification number: G01N24/006 , G01N24/08 , G01N33/381
Abstract: Systems and methods of quantum sensing include obtaining information regarding a target signal in electronic spin states of quantum defects in an ensemble of quantum defects, mapping the information regarding the target signal from the electronic spin states of the quantum defects to corresponding nuclear spin states associated with the quantum defects, applying a light pulse to the ensemble of quantum defects to reset the electronic spin states of the quantum defects, and repeating a readout stage a plurality of times within a readout duration. The readout stage includes mapping the information regarding the target signal back from the nuclear spin states to the corresponding electronic spin states and applying a data acquisition readout pulse to optically measure the electronic spin states of the quantum defects.
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公开(公告)号:US11846690B2
公开(公告)日:2023-12-19
申请号:US17863846
申请日:2022-07-13
Inventor: Peter J. Basser , Dan H. Benjamini
IPC: G01R33/46 , G01R33/465 , G01R33/44 , G01R33/563 , G01N24/08
CPC classification number: G01R33/465 , G01R33/448 , G01R33/56341 , G01N24/08 , G01R33/4625 , G01R33/4633
Abstract: Multi-dimensional spectra associated with a specimen are reconstructed using lower dimensional spectra as constraints. For example, a two-dimensional spectrum associated with diffusivity and spin-lattice relaxation time is obtained using one-dimensional spectra associated with diffusivity and spin-lattice relaxation time, respectively, as constraints. Data for a full two dimensional spectrum are not acquired, leading to significantly reduced data acquisition times.
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