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公开(公告)号:US3732077A
公开(公告)日:1973-05-08
申请号:US3732077D
申请日:1971-10-29
Applicant: DAMON CORP
Inventor: FOSTER L , HOCHHOLZER J
IPC: G01N33/487 , G01N33/62 , G01N33/16 , G01N21/24
CPC classification number: G01N33/62 , Y10T436/171538
Abstract: Blood serum is tested for the presence of urea nitrogen by reacting urea present in the serum with an aqueous reagent having a pH of between 0.4 and 1.5 and containing diacetylmonoxime, phenazone, arsenic pentoxide and sulfuric acid. Reaction is effected by heating the serum-reagent mixture to 85* to 100* C., cooling and measuring the optical absorbance of the cooled mixture at a wavelength between 450 and 485 nm.
Abstract translation: 通过使血清中存在的尿素与pH为0.4〜1.5的水性试剂反应并含有二乙酰单肟,吩噻嗪,五氧化二砷和硫酸,对血清进行尿素氮的存在。 通过将血清试剂混合物加热至85℃至100℃进行反应,冷却并测量冷却的混合物在450和485nm之间的波长的光吸收。
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公开(公告)号:US3598533A
公开(公告)日:1971-08-10
申请号:US3598533D
申请日:1969-04-01
Applicant: CHUGAI PHARMACEUTICAL CO LTD
Inventor: TOMIOKA SUIICHI , SHIBA MOTOHARU , WADE SAKAE
CPC classification number: C12Q1/46 , C12Q2334/00 , G01N33/523 , G01N33/62 , G01N33/84 , Y10T436/171538
Abstract: AN IMPROVED DIAGNOSTIC PAPER STRIP WHICH IS APPLICABLE TO WHOLE BLOOD SAMPLE, WHICH IS PREPARED BY DIPPING A DIAGNOSTIC PAPER STRIP INTO ORGANIC SOLVENT SOLUTION OF ONE OR MORE OF CHOLESTEROL, ROSIN AND THEIR ESTERS AND DRYING THE STRIP.
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公开(公告)号:US3511611A
公开(公告)日:1970-05-12
申请号:US3511611D
申请日:1968-01-23
Applicant: PFIZER & CO C
Inventor: RUSH ROBERT L
CPC classification number: G01N33/62 , Y10T436/171538
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公开(公告)号:US12117454B2
公开(公告)日:2024-10-15
申请号:US16868644
申请日:2020-05-07
Applicant: Roche Diagnostics Operations, Inc.
Inventor: Dirk Block , Hans-Peter Brunner , Ursula-Henrike Wienhues-Thelen , Christian Zaugg , Thomas Dieterle , Cheryl Mitchell , Johan Ubby , Sandra Sanders-van Wijk
CPC classification number: G01N33/6893 , G01N33/62 , G01N33/66 , G01N33/6869 , G01N33/6887 , G01N33/70 , G01N33/723 , G01N33/84 , G01N2333/4737 , G01N2333/5412 , G01N2333/58 , G01N2333/78 , G01N2333/805 , G01N2800/325 , G01N2800/347 , G01N2800/52
Abstract: Methods for identifying a patient who is eligible for an intensification of heart failure therapy are disclosed. Furthermore, methods for optimizing B-type natriuretic peptide (BNP) and/or N-terminal pro B-type natriuretic peptide (NT-proBNP)-type peptide guided heart failure therapy are disclosed. The methods are based on the measurement of the level of at least one marker in a sample from a patient who has heart failure and who receives B-type natriuretic peptide (BNP) and/or N-terminal pro B-type natriuretic peptide (NT-proBNP)-type peptide guided heart failure therapy. Further described are kits and devices adapted to carry out the described methods.
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公开(公告)号:US20240230537A1
公开(公告)日:2024-07-11
申请号:US18430155
申请日:2024-02-01
Applicant: Endress+Hauser Optical Analysis, Inc.
Inventor: Carsten Uerpmann , Michael Gordon Stidham
CPC classification number: G01N21/65 , G01J3/0202 , G01J3/0205 , G01N21/8507 , G01N33/62 , G01N2021/8528 , G01N2201/06113
Abstract: One aspect of the present disclosure discloses a probe, including a probe body having a center axis defining a proximal end and a distal end and including an aperture in the distal end; a window affixed in the aperture, wherein the window is substantially optically transparent; and a flange adjoining the proximal end of the probe body, the flange including a sealing surface and a sealing edge, wherein the flange separates an in-process portion of the probe from an ex-process portion of the probe, the in-process portion including at least the probe body, the sealing surface and the sealing edge, where at least the in-process portion of the probe consists essentially of an austenitic stainless steel material. Further aspects include a computer product configured to execute a method employing the probe.
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公开(公告)号:US20230381271A1
公开(公告)日:2023-11-30
申请号:US18361775
申请日:2023-07-28
Applicant: Aurinia Pharmaceuticals Inc.
Inventor: Michael Martin , Robert B. Huizinga , Neil Solomons
IPC: A61K38/13 , A61K31/5377 , A61K31/573 , A61P37/06 , A61P13/12 , G01N33/70 , G01N33/62 , G01N33/68 , G01N33/92 , G01N33/53
CPC classification number: A61K38/13 , A61K31/5377 , A61K31/573 , A61P37/06 , A61P13/12 , G01N33/70 , G01N33/62 , G01N33/6893 , G01N33/92 , G01N33/5308 , G01N2800/52 , G01N2800/347
Abstract: Provided herein are methods of employing pharmacodynamics regimens to maximize effectiveness of voclosporin in treatment of proteinuric kidney diseases while minimizing undesirable side effects, such as but not limited to calcineurin inhibitor nephrotoxicity. Also provided are methods of assessments of renal functions and/or conditions, and corresponding protocols to modify, stop, restore and/or re-initiate voclosporin dosing and administrations to maximize effectiveness of voclosporin in treatment of proteinuric kidney diseases while minimizing undesirable side effects.
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公开(公告)号:US20180348209A1
公开(公告)日:2018-12-06
申请号:US15778952
申请日:2016-11-23
Applicant: Infagen (Hong Kong) Limited
Inventor: Barry Marshall
IPC: G01N33/52
Abstract: The present invention relates to a kit for the detection of urease and to a tool and a composition forming part of the kit. In particular, the present invention relates to a kit for the detection of urease which comprises a composition containing an indicator; a delivery tool arranged to deliver a tissue sample into contact with the composition; and urea carried on the delivery tool, whereby the urea is arranged to be delivered to the composition together with the tissue sample.
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公开(公告)号:US20160370396A1
公开(公告)日:2016-12-22
申请号:US15161533
申请日:2016-05-23
Applicant: Theranos, Inc.
Inventor: James Wasson , Pey-Jiun Ko , Joy Roy , Elizabeth A. Holmes
CPC classification number: G01N35/0092 , B01L3/021 , B01L3/5082 , B01L3/50855 , B01L7/52 , B01L9/06 , B01L9/52 , B01L9/543 , B01L2300/1827 , B01L2300/1855 , C12Q1/42 , C12Q1/52 , C12Q1/6883 , C12Q1/70 , G01N15/1475 , G01N21/25 , G01N21/27 , G01N33/5005 , G01N33/54306 , G01N33/54313 , G01N33/54366 , G01N33/56983 , G01N33/62 , G01N33/6827 , G01N33/80 , G01N33/92 , G01N35/00 , G01N35/00029 , G01N35/00069 , G01N35/00623 , G01N35/00871 , G01N35/026 , G01N35/04 , G01N35/10 , G01N35/1009 , G01N35/1011 , G01N35/1065 , G01N35/1072 , G01N2015/0073 , G01N2015/008 , G01N2015/1006 , G01N2015/1486 , G01N2035/00138 , G01N2035/00148 , G01N2035/00237 , G01N2035/00306 , G01N2035/00326 , G01N2035/00356 , G01N2035/00366 , G01N2035/00425 , G01N2035/00435 , G01N2035/00495 , G01N2035/00633 , G01N2035/0449 , G01N2035/0474 , G01N2035/0486 , G01N2035/0491 , G01N2035/0493 , G01N2035/0494 , G01N2201/024 , G01N2201/04 , G01N2201/12 , Y10T436/111666 , Y10T436/113332
Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.
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公开(公告)号:US20160370347A1
公开(公告)日:2016-12-22
申请号:US15251399
申请日:2016-08-30
Applicant: Church & Dwight Co., Inc.
Inventor: Andy Sturman , Benedict Zin , Albert Nazareth , Henry Bell
IPC: G01N33/487 , G01N21/84 , G01N21/17 , G01N33/76 , G01N33/68
CPC classification number: G01N33/48792 , G01N21/17 , G01N21/8483 , G01N33/48785 , G01N33/493 , G01N33/62 , G01N33/689 , G01N33/76 , G01N2201/062 , G01N2201/12 , G01N2333/59
Abstract: An improved electronic diagnostic device for detecting the presence of an analyte in a fluid sample comprises a casing having a display, a test strip mounted in the casing, a processor mounted in the casing, and a first sensor mounted in the casing and operatively coupled to the processor. The processor is configured to receive a signal from the first sensor when the device is exposed to ambient light thereby causing the device to become activated. The device includes a light shield that exerts pressure across a width of the test strip to prevent fluid channeling along the length of the test strip. The processor is configured to present an early positive test result reading when a measured value exceeds a predetermined early reading threshold value at any time after a predetermined early testing time period.
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公开(公告)号:US20160370346A1
公开(公告)日:2016-12-22
申请号:US15251370
申请日:2016-08-30
Applicant: Church & Dwight Co., Inc.
Inventor: Andy Sturman , Benedict Zin , Albert Nazareth , Henry Bell
IPC: G01N33/487 , G01N21/17 , G01N21/84 , G01N33/76 , G01N33/68
CPC classification number: G01N33/48792 , G01N21/17 , G01N21/8483 , G01N33/48785 , G01N33/493 , G01N33/62 , G01N33/689 , G01N33/76 , G01N2201/062 , G01N2201/12 , G01N2333/59
Abstract: An improved electronic diagnostic device for detecting the presence of an analyte in a fluid sample comprises a casing having a display, a test strip mounted in the casing, a processor mounted in the casing, and a first sensor mounted in the casing and operatively coupled to the processor. The processor is configured to receive a signal from the first sensor when the device is exposed to ambient light thereby causing the device to become activated. The device includes a light shield that exerts pressure across a width of the test strip to prevent fluid channeling along the length of the test strip. The processor is configured to present an early positive test result reading when a measured value exceeds a predetermined early reading threshold value at any time after a predetermined early testing time period.
Abstract translation: 用于检测流体样品中分析物的存在的改进的电子诊断装置包括具有显示器的壳体,安装在壳体中的测试条,安装在壳体中的处理器,以及安装在壳体中并可操作地耦合到 处理器。 该处理器被配置为当该设备暴露于环境光从而导致该设备被激活时从第一传感器接收信号。 该装置包括遮光板,其在测试条的宽度上施加压力,以防止沿着测试条的长度的流体通道。 处理器被配置为当在预定的早期测试时间段之后的任何时间测量值超过预定的早期读取阈值时呈现早期的正测试结果读数。
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