-
公开(公告)号：US20090311671A1
公开(公告)日：2009-12-17
申请号：US10570588
申请日：2004-09-02
Applicant: Martin Andrew Crockard , Janice Roberta Bailie , John Victor Lamont , Stephen Peter Fitzgerald
Inventor： Martin Andrew Crockard , Janice Roberta Bailie , John Victor Lamont , Stephen Peter Fitzgerald
CPC classification number: C12Q1/6886 , C12Q2600/158
Abstract: A diagnostic method is disclosed which can he used to predict the risk of cancer, in particular breast cancer. The method comprises: (i) isolating a sample of the patient's genome: and (ii) detecting the presence or expression of the gene comprised within the sequence identified herein as SEQ ID No. 1, wherein the presence or expression of the gene indicates the presence of or the risk of cancer.
Abstract translation: 公开了一种诊断方法，可用于预测癌症的风险，特别是乳腺癌。 该方法包括：（i）分离患者基因组的样品;和（ii）检测包含在本文鉴定的序列中的基因的存在或表达，如SEQ ID No.1，其中基因的存在或表达指示 癌症的存在或风险。
-
公开(公告)号：US20090233811A1
公开(公告)日：2009-09-17
申请号：US11989134
申请日：2006-07-31
Applicant: Sorin Bota , Ekaterina Arikainen , Robert Ivan McConnell , Stephen Peter Fitzgerald
Inventor： Sorin Bota , Ekaterina Arikainen , Robert Ivan McConnell , Stephen Peter Fitzgerald
CPC classification number: B01J19/0046 , B01J2219/00545 , B01J2219/00554 , B01J2219/00576 , B01J2219/00659 , B01J2219/00662 , B01J2219/00693 , B01J2219/0072 , B01J2219/00722 , B01J2219/00725 , B01J2219/0074 , G01N33/552 , G01N2035/00158 , G01N2035/00168
Abstract: The present invention relates to a method of manufacturing an array chip, comprising the steps of: i) depositing at least one ligand onto the active surface of a wafer substrate, having at least one scribe line, the active surface being the reverse of the surface comprising the at least one scribe line; ii) detecting the ligand in relation to the at least one scribe line; and iii) breaking the wafer substrate along the at least one scribe line, to produce at least one array chip.
Abstract translation: 本发明涉及一种制造阵列芯片的方法，包括以下步骤：i）将至少一种配体沉积到晶片衬底的有源表面上，具有至少一个划线，该活性表面与表面相反 包括所述至少一个划线; ii）相对于至少一个划线检测配体; 以及iii）沿着所述至少一个划线断开所述晶片衬底，以产生至少一个阵列芯片。
-
公开(公告)号：US07241630B2
公开(公告)日：2007-07-10
申请号：US09816225
申请日：2001-03-26
Applicant: Peter Hawkins , Richard William Luxton
Inventor： Peter Hawkins , Richard William Luxton
CPC classification number: G01R33/1223 , Y10S436/804
Abstract: A method of determining the number of magnetic particles within a sample using a tuned circuit having a capacitor and a coil. The method comprises: a. determining the difference in the resonant frequency of the tuned circuit when the sample is exposed to a magnetic field generated by the coil and when the sample is not exposed to the magnetic field generated by the coil; and b. using the difference in the resonant frequency to determine the number of magnetic particles within the sample.
Abstract translation: 使用具有电容器和线圈的调谐电路来确定样品内的磁性颗粒数量的方法。 该方法包括：a。 当样品暴露于由线圈产生的磁场和样品不暴露于由线圈产生的磁场时，确定调谐电路的谐振频率的差异; 和b。 使用谐振频率的差异来确定样品中的磁性颗粒的数量。
-
公开(公告)号：US06902897B2
公开(公告)日：2005-06-07
申请号：US10188796
申请日：2002-07-05
Applicant: Mark Tweedie , John Victor Lamont , Robert Ivan McConnell , Stephen Peter Fitzgerald
Inventor： Mark Tweedie , John Victor Lamont , Robert Ivan McConnell , Stephen Peter Fitzgerald
CPC classification number: G01N35/00603 , B01J19/0046 , B01J2219/00351 , B01J2219/00527 , B01J2219/00529 , B01J2219/0054 , B01J2219/00545 , B01J2219/00547 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00659 , B01J2219/00677 , B01J2219/00689 , B01J2219/00691 , B01J2219/00693 , B01L3/0268 , B82Y30/00 , C40B60/14 , C40B70/00 , G01N35/10 , G01N2035/1034
Abstract: A biochip deposition system and method. The system comprises a deposit mechanism for depositing organic material in spots on a substrate; and a viewing system for detecting the spots on the substrate during a deposit operation and before the spots have dried, for determining if the spots have been correctly deposited, and if not, for generating a suitable output signal. The viewing system includes an illumination device for illuminating deposited spots at a relatively low angle relative to the substrate.
Abstract translation: 一种生物芯片沉积系统及方法。 该系统包括用于在基板上的点沉积有机材料的沉积机构; 以及观察系统，用于在沉积操作期间和斑点干燥之前检测基板上的斑点，以确定斑点是否已被正确沉积，如果不是，则用于产生合适的输出信号。 观察系统包括用于以相对于衬底相对低的角度照射沉积点的照明装置。
-
公开(公告)号：US06897026B2
公开(公告)日：2005-05-24
申请号：US10046728
申请日：2002-01-17
Applicant: John Victor Lamont , Robert Ivan McConnell , Stephen Peter Fitzgerald
Inventor： John Victor Lamont , Robert Ivan McConnell , Stephen Peter Fitzgerald
IPC: G01N33/53 , C12M1/34 , C40B40/06 , C40B40/10 , C40B50/08 , G01N21/25 , G01N21/78 , G01N33/566 , G01N37/00 , C12Q1/68 , C07H21/04 , C12M1/36 , G01N21/47
CPC classification number: B82Y30/00 , B01J2219/00274 , B01J2219/00497 , B01J2219/00527 , B01J2219/00576 , B01J2219/00585 , B01J2219/00599 , B01J2219/00605 , B01J2219/00612 , B01J2219/00626 , B01J2219/00659 , B01J2219/00662 , B01J2219/00677 , B01J2219/00693 , B01J2219/00722 , B01J2219/00725 , C40B40/06 , C40B40/10 , C40B50/08 , G01N21/253
Abstract: A method for imaging molecules contained in an array of discrete reaction sites on the surface of a solid support comprises: (i) imaging the array and detecting a first molecule located on the solid support at a known position with respect to the array; (ii) by reference to the first molecule, aligning inspection windows in registration with the discrete reaction sites; and (iii) determining the amount of detectable signal in each window. The method is used to locate the reaction sites accurately on the array, and to correct for any misalignments.
Abstract translation: 用于对包含在固体支持物表面上的离散反应位点阵列中的分子进行成像的分子的方法包括：（i）对阵列进行成像并检测位于相对于阵列的已知位置的固体支持物上的第一分子; （ii）通过参考第一分子，将检查窗对准离散的反应位点; 和（iii）确定每个窗口中的可检测信号的量。 该方法用于在阵列上准确定位反应位点，并纠正任何错位。
-
Patent Agency Ranking
公开(公告)号：US20020146847A1
公开(公告)日：2002-10-10
申请号：US10046728
申请日：2002-01-17
Applicant: RANDOX LABORATORIES LTD.
Inventor： John Victor Lamont , Robert Ivan McConnell , Stephen Peter Fitzgerald
IPC: C12Q001/68 , G01N033/543 , G06K009/00 , G06F019/00 , G01N033/48 , G01N033/50
CPC classification number: B82Y30/00 , B01J2219/00274 , B01J2219/00497 , B01J2219/00527 , B01J2219/00576 , B01J2219/00585 , B01J2219/00599 , B01J2219/00605 , B01J2219/00612 , B01J2219/00626 , B01J2219/00659 , B01J2219/00662 , B01J2219/00677 , B01J2219/00693 , B01J2219/00722 , B01J2219/00725 , C40B40/06 , C40B40/10 , C40B50/08 , G01N21/253
Abstract: A method for imaging molecules contained in an array of discrete reaction sites on the surface of a solid support comprises: (i) imaging the array and detecting a first molecule located on the solid support at a known position with respect to the array; (ii) by reference to the first molecule, aligning inspection windows in registration with the discrete reaction sites; and (iii) determining the amount of detectable signal in each window. The method is used to locate the reaction sites accurately on the array, and to correct for any misalignments.
Abstract translation: 用于对包含在固体支持物表面上的离散反应位点阵列中的分子进行成像的分子的方法包括：（i）对阵列进行成像并检测位于相对于阵列的已知位置的固体支持物上的第一分子; （ii）通过参考第一分子，将检查窗对准离散的反应位点; 和（iii）确定每个窗口中的可检测信号的量。 该方法用于在阵列上准确定位反应位点，并纠正任何错位。
-
公开(公告)号：US20250003987A1
公开(公告)日：2025-01-02
申请号：US18707545
申请日：2022-11-08
Applicant: Randox Laboratories Ltd.
Inventor： Paul Innocenzi , Stephen Peter Fitzgerald , Ivan McConnell
Abstract: A method is described for the identification of individuals with a BMI of less than 25 who have a biochemical profile that corresponds to an overweight or obese phenotype. The method of highlighting this hidden obesity makes use of various biomarker combinations that can incorporate various analytes including leptin and complement C3.
-
公开(公告)号：US20240201178A1
公开(公告)日：2024-06-20
申请号：US18284783
申请日：2022-03-31
Applicant: RANDOX LABORATORIES LTD. , RANDOX TEORANTA
Inventor： Peter Fitzgerald , John Victor Lamont , Ivan McConnell , Ciaran Richardson , Philip Lowry , Jim Curry
IPC: G01N33/543 , G01N33/68
CPC classification number: G01N33/54353 , G01N33/54393 , G01N33/6857 , G01N2650/00
Abstract: The present invention relates to improved detection assays via the utilisation of a substrate with an analyte immobilised on its surface by means of a linking agent and a cross-linker. The present invention also relates to a method of producing a substrate for use in detection assays and a method of detecting an analyte using said substrate.
-
公开(公告)号：US20240091783A1
公开(公告)日：2024-03-21
申请号：US18273737
申请日：2022-01-21
Applicant: RANDOX LABORATORIES LTD , Randox Teoranta
Inventor： Dale Love , Peter Fitzgerald , Ivan McConnell , Christina McFadden
IPC: B01L9/00
CPC classification number: B01L9/523 , B01L2200/025
Abstract: There is provided a bracket for a biological sample analyser. The bracket comprises abase and an arm extending from the base, the base being engageable with a platform of a biological sample analyser, wherein, when the base is engaged with the platform, the arm extends into a sample plate bay of the biological sample analyser prohibiting access to a portion of the bay. The arm thereby limits misalignment of a sample plate in the bay by blocking access to a portion of the bay only required when the sample plate is loaded into the bay in an incorrect orientation. A biological sample analyser comprising a bay in which a sample plate is loadable in use and the bracket is also provided.
-
公开(公告)号：US20240003910A1
公开(公告)日：2024-01-04
申请号：US18037968
申请日：2021-11-15
Applicant: RANDOX LABORATORIES LTD
Inventor： Paul Innocenzi , Peter Fitzgerald , McMaster Steven
IPC: G01N33/68
CPC classification number: G01N33/6893 , G01N2800/7042
Abstract: Methods and products for adjusting the chronological age of a biological system or an individual to provide finer scale insight to health status are provided. The methods are underpinned by various serum and urinary biomarkers including antistreptolysin.
-
-
-
-
-
-
-
-
-
Search Results
107
records
(took 0.033 seconds)
