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公开(公告)号:US20250044313A1
公开(公告)日:2025-02-06
申请号:US18717649
申请日:2022-12-09
Applicant: RANDOX LABORATORIES LTD.
Inventor: Ivan MCCONNELL , Lewis MCKINSTRY , Peter FITZGERALD
IPC: G01N35/02 , G01N33/543 , G01N35/00 , G01N35/04
Abstract: An apparatus for assaying one or more lateral flow test devices. The apparatus comprises at least one support device for supporting one or more lateral flow test devices in use and at least one sample receptacle configured to receive, in use, a respective liquid sample to be dispensed onto a corresponding lateral flow test device. The apparatus further comprises a dispensing apparatus configured to dispense a known volume of the received liquid sample from the sample receptacle onto the corresponding lateral flow test device supported by the support device.
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公开(公告)号:US12208397B2
公开(公告)日:2025-01-28
申请号:US17265441
申请日:2019-08-02
Applicant: RANDOX LABORATORIES LTD
Inventor: Paul Courtney , Martin Reid , Stuart Jackson , John Lamont , Ivan McConnell , Peter Fitzgerald
Abstract: There is provided a pipette tip disposal assembly. The assembly comprises a receiving element adapted to support an end of at least one pipette tip, the at least one pipette tip being toppled in use from the receiving element along a first direction; and a container positioned to receive the at least one toppled pipette tip, the at least one pipette tip falling towards a base of the container on being received by the container. The base of the container has a first linear dimension aligned with the first direction corresponding to the length of a pipette tip.
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公开(公告)号:US20200166465A1
公开(公告)日:2020-05-28
申请号:US16632270
申请日:2018-07-18
Applicant: Randox Laboratories Ltd
Inventor: Marc Wharry , P. Evans , Stuart Jackson
Abstract: There is provided a chemiluminescence detector sample enclosure. The enclosure comprises a first interface member forming part of a chemiluminescence detector and having a first sealing element and a second interface member comprising a plurality of sample holders, each sample holder having a second sealing element. The first interface member is engagable with and moveable between sample holder subsets of the plurality of sample holders, engagement with a respective sample holder subset providing engagement of the first interface member with each sample holder of the respective sample holder subset and relative movement of the first and second interface members providing movement between sample holder subsets; and when the first interface member is engaged with each respective sample holder, the first sealing element and the respective second sealing element are adapted to interact so as to form a light restricting seal between the first interface member and said sample holder.
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公开(公告)号:US20190247820A1
公开(公告)日:2019-08-15
申请号:US16388527
申请日:2019-04-18
Applicant: Randox Laboratories Ltd. , Randox Teoranta
Inventor: Peter Fitzgerald , John Lamont , Ivan McConnell , Elouard Benchikh , Deepesh Upadhyay , Ciaran Richardson
IPC: B01J19/00 , C12M1/00 , G01N33/543 , C09D11/102 , C09D11/03
CPC classification number: B01J19/0046 , B01J2219/00608 , B01J2219/00637 , C09D11/03 , C09D11/102 , C12M1/00 , G01N33/54393
Abstract: A substrate comprising a coating of a masking material, and a plurality of discrete reaction zones onto which one or more binding agents are intended to be attached, wherein said zones are uncoated areas on the substrate.
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公开(公告)号:US10288618B2
公开(公告)日:2019-05-14
申请号:US15302849
申请日:2015-04-02
Applicant: Randox Laboratories Ltd.
Inventor: Alex Chacko , Ivan McConnell , Peter Fitzgerald , John V. Lamont
Abstract: The present invention describes methods for screening for cancer in a subject, by measuring the level of dimeric IL-18 in a sample obtained from the subject, and comparing that level with the level in a normal control sample.The present invention also describes an assay for screening for cancer in a subject, by measuring the level of dimeric IL-18 in a sample obtained from the subject, whereby an elevated level of dimeric IL-18 is indicative of cancer.
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公开(公告)号:US10279332B2
公开(公告)日:2019-05-07
申请号:US15983484
申请日:2018-05-18
Applicant: Randox Laboratories Ltd. , Randox Teoranta
Inventor: Peter Fitzgerald , John Lamont , Ivan McConnell , Elouard Benchikh , Deepesh Upadhyay , Ciaran Richardson
IPC: B01J19/00 , C09D11/03 , C09D11/102 , C12M1/00 , G01N33/543
Abstract: A substrate comprising a coating of a masking material, and a plurality of discrete reaction zones onto which one or more binding agents are intended to be attached, wherein said zones are uncoated areas on the substrate.
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公开(公告)号:US10254297B2
公开(公告)日:2019-04-09
申请号:US15200558
申请日:2016-07-01
Applicant: Randox Laboratories Ltd
Inventor: Ivan McConnell , Philip Lowry , Elouard Benchikh , Peter Fitzgerald
IPC: G01N33/94 , C07K14/435 , C07K16/44 , C07C225/20 , C07C229/14
Abstract: Components for enabling immunodetection of methoxetamine are described including immunogens, haptens, antibodies and kits.
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公开(公告)号:US20180339282A1
公开(公告)日:2018-11-29
申请号:US15983484
申请日:2018-05-18
Applicant: Randox Laboratories Ltd. , Randox Teoranta
Inventor: Peter Fitzgerald , John Lamont , Ivan McConnell , Elouard Benchikh , Deepesh Upadhyay , Ciaran Richardson
IPC: B01J19/00 , C09D11/03 , C09D11/102 , C12M1/00
CPC classification number: B01J19/0046 , B01J2219/00608 , B01J2219/00637 , C09D11/03 , C09D11/102 , C12M1/00 , G01N33/54393
Abstract: A substrate comprising a coating of a masking material, and a plurality of discrete reaction zones onto which one or more binding agents are intended to be attached, wherein said zones are uncoated areas on the substrate.
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公开(公告)号:US09707561B2
公开(公告)日:2017-07-18
申请号:US15038024
申请日:2014-11-19
Applicant: Randox Laboratories Ltd.
Inventor: Jonathan Matear , Robson Pang , Stuart Jackson , David Sloan
CPC classification number: B01L3/50273 , B01L3/502715 , B01L3/527 , B01L2200/027 , B01L2200/04 , B01L2200/0605 , B01L2200/0621 , B01L2200/10 , B01L2200/16 , B01L2300/0816 , B01L2300/123 , B01L2400/0478 , B01L2400/0481 , B01L2400/0487 , F04B9/042 , G01N35/00029 , G01N35/1002 , G01N2035/00148 , G01N2035/0486
Abstract: There is provided an assay fluid delivery system comprising an array of fluid reservoirs (62), each of which is selectively actuatable to deliver a respective fluid to a fluid channel structure; and a fluid delivery control system (50) comprising a plurality of reciprocally mounted actuators, each associated with a respective reservoir and being movable between a retracted position and an actuating position at which it causes fluid to be delivered from the corresponding reservoir, a plurality of cams (22) with different profiles mounted on a common, rotatable cam shaft (6), each cam being engaged with a respective one of the actuators whereby rotation of the cams causes movement of the corresponding actuators between the retracted and actuating positions, and a motor coupled to the cam shaft for rotating the cam shaft, wherein the cams are shaped relative to one another so as to cause the corresponding actuators to actuate the reservoirs in a predetermined sequence and for predetermined respective times.
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10.
公开(公告)号:US20160266020A1
公开(公告)日:2016-09-15
申请号:US15036811
申请日:2014-11-13
Applicant: RANDOX LABORATORIES LTD
Inventor: Michael Veitinger , Maria Zellner
CPC classification number: G01N1/4077 , C12Q1/485 , G01N33/6842 , G01N33/86
Abstract: The present invention provides a novel method of in vitro sample preparation for the analysis of proteins. In a first aspect, the present invention is a method comprising the separation and individual treatment of blood platelets and platelet-poor plasma obtained from a platelet-rich plasma sample. This allows for optimal treatment of both fractions and overcomes many of the problems associated with current methods. In a second aspect of the present invention the platelet sample preparation method can be implemented before a biochip based immunoassay for the detection of platelet proteins in combination with plasma proteins.
Abstract translation: 本发明提供了用于分析蛋白质的体外样品制备的新方法。 在第一方面,本发明是一种包括从富含血小板的血浆样品中分离和单独处理血小板和血小板不足血浆的方法。 这允许对两个级分进行最佳处理并克服与当前方法相关的许多问题。 在本发明的第二方面,血小板样品制备方法可以在用于检测与血浆蛋白质组合的血小板蛋白质的基于生物芯片的免疫测定之前实施。
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