公开(公告)号：US10254297B2

公开(公告)日：2019-04-09

申请号：US15200558

申请日：2016-07-01

Applicant: Randox Laboratories Ltd

Inventor： Ivan McConnell ,  Philip Lowry ,  Elouard Benchikh ,  Peter Fitzgerald

IPC: G01N33/94 ,  C07K14/435 ,  C07K16/44 ,  C07C225/20 ,  C07C229/14

Abstract: Components for enabling immunodetection of methoxetamine are described including immunogens, haptens, antibodies and kits.

公开(公告)号：US10815192B2

公开(公告)日：2020-10-27

申请号：US15903361

申请日：2018-02-23

Applicant: Randox Laboratories Ltd.

Inventor： Ivan McConnell ,  Peter Fitzgerald ,  Elouard Benchikh ,  Philip Lowry

IPC: C07C233/79 ,  C07K16/18 ,  G01N33/94 ,  G01N33/53 ,  C07K16/44 ,  C07K16/16

Abstract: Antibodies, immunoassay methods and kits for the detection and determination of 3,4,-dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide and 3,4,-dichloro-N-[2-(methylamino)cyclohexyl]-N-methylbenzamide, as well as the precursory immunogens, are described.

公开(公告)号：US20170003308A1

公开(公告)日：2017-01-05

申请号：US15200558

申请日：2016-07-01

Applicant: Randox Laboratories Ltd

Inventor： Ivan McConnell ,  Philip Lowry ,  Elouard Benchikh ,  Peter Fitzgerald

IPC: G01N33/94 ,  C07C225/20 ,  C07C229/14 ,  C07K16/44 ,  C07K14/435

CPC classification number: G01N33/94 ,  C07C225/20 ,  C07C229/14 ,  C07K14/43504 ,  C07K16/44 ,  C07K2317/33 ,  C07K2317/92

Abstract: Components for enabling immunodetection of methoxetamine are described including immunogens, haptens, antibodies and kits.

Abstract translation: 描述了用于实现甲氧胺的免疫检测的组分，包括免疫原，半抗原，抗体和试剂盒。

公开(公告)号：US20160245800A1

公开(公告)日：2016-08-25

申请号：US15042095

申请日：2016-02-11

Applicant: Randox Laboratories Ltd.

Inventor： Elouard Benchik ,  Ivan McConnell ,  Peter FitzGerald ,  Philip Lowry

IPC: G01N33/53 ,  C07K16/44

CPC classification number: G01N33/5308 ,  C07K16/44 ,  C07K2317/14 ,  C07K2317/33 ,  C07K2317/92 ,  G01N33/9486

Abstract: Antibodies, immunoassay methods and kits for the detection and determination of 3,4,-dichloro-N-[(1-(dimethylamino)cyclohexyl)methyl]benzamide and 3,4,-dichloro-N-[(1-(methylamino)cyclohexyl)methyl]benzamide, as well as the precursory immunogens, are described.

Abstract translation: 用于检测和测定3,4， - 二氯-N - [（1-（二甲基氨基）环己基）甲基]苯甲酰胺和3,4， - 二氯-N - [（1-（甲基氨基）苯基）苯甲酰胺的抗体，免疫测定方法和试剂盒， 环己基）甲基]苯甲酰胺，以及前体免疫原。

公开(公告)号：US10539557B2

公开(公告)日：2020-01-21

申请号：US15042095

申请日：2016-02-11

Applicant: Randox Laboratories Ltd.

Inventor： Elouard Benchikh ,  Ivan McConnell ,  Peter FitzGerald ,  Philip Lowry

IPC: G01N33/53 ,  C07K16/44

Abstract: Antibodies, immunoassay methods and kits for the detection and determination of 3,4-dichloro-N-[(1-(dimethylamino)cyclohexyl)methyl]benzamide and 3,4-dichloro-N-[(1-(methylamino)cyclohexyl)methyl]benzamide, as well as the precursory immunogens, are described.

公开(公告)号：US20240201178A1

公开(公告)日：2024-06-20

申请号：US18284783

申请日：2022-03-31

Applicant: RANDOX LABORATORIES LTD. ,  RANDOX TEORANTA

Inventor： Peter Fitzgerald ,  John Victor Lamont ,  Ivan McConnell ,  Ciaran Richardson ,  Philip Lowry ,  Jim Curry

IPC: G01N33/543 ,  G01N33/68

CPC classification number: G01N33/54353 ,  G01N33/54393 ,  G01N33/6857 ,  G01N2650/00

Abstract: The present invention relates to improved detection assays via the utilisation of a substrate with an analyte immobilised on its surface by means of a linking agent and a cross-linker. The present invention also relates to a method of producing a substrate for use in detection assays and a method of detecting an analyte using said substrate.