公开(公告)号：US20190041366A1

公开(公告)日：2019-02-07

申请号：US16053139

申请日：2018-08-02

申请人： SHIMADZU CORPORATION

发明人： Daisuke KAWAKAMI

IPC分类号： G01N30/06 ,  G01N30/20 ,  G01N35/10 ,  G01N35/02

摘要： To provide a preprocessing apparatus with a function of stirring and sucking a sample in a sample container carried on a conveyor line outside the preprocessing apparatus.The preprocessing apparatus includes a sampling unit, a unit that stirs a sample before suction, and a stirring operation control unit. The sampling unit includes a sample probe that sucks a sample in the sample container, and is configured to move the sample probe to the sample container set in the sample container setting part and to an external suction location set on a conveyor line located outside the preprocessing apparatus. The unit that stirs a sample before suction includes a stirring probe which stirs a sample in the sample container, and moves the stirring probe at least to the external suction location or a location upstream of the external suction location on the conveyor line. The stirring operation control unit is configured to control operation of the sampling unit and the unit that stirs a sample before suction so that a sample in the sample container is stirred by the stirring probe before the sample is sucked by the sample probe.

公开(公告)号：US10175198B2

公开(公告)日：2019-01-08

申请号：US15434841

申请日：2017-02-16

申请人： INFICON, Inc.

发明人： Shawn Michael Briglin ,  Katherine Abigail Bartholomew

IPC分类号： G01N1/22 ,  G01N27/64 ,  G01N30/72 ,  G01N30/06 ,  G01N30/86 ,  G01N30/64

摘要： A system and method for chemical analysis are described herein. The system includes a probe, a sample collection cartridge, and a chemical analyzer. The probe is configured to collect the optimal amount of sample for a future analysis and to store this chemical sample in the sample collection cartridge. The probe also collects sample data. The chemical analyzer is configured to determine the optimal analysis settings based on the sample data and analyze the chemical sample stored in the sample collection cartridge based on the optimal analysis settings.

公开(公告)号：US20180217113A1

公开(公告)日：2018-08-02

申请号：US15938450

申请日：2018-03-28

申请人： Ajinomoto Co., Inc.

发明人： Masashi Harada ,  Sachise Karakawa ,  Kazutaka Shimbo ,  Naoyuki Yamada

IPC分类号： G01N30/88 ,  C07D207/46 ,  C07D401/12 ,  C07C271/58 ,  C07D213/40 ,  C07C53/18 ,  C07C51/47 ,  G01N1/40 ,  C07C269/08 ,  C07C269/06 ,  C07C51/353 ,  G01N27/62 ,  G01N30/06 ,  G01N30/72 ,  B01D15/32

CPC分类号： G01N30/88 ,  B01D15/327 ,  B01D15/38 ,  C07B57/00 ,  C07B2200/07 ,  C07C51/353 ,  C07C51/47 ,  C07C53/18 ,  C07C233/62 ,  C07C269/06 ,  C07C269/08 ,  C07C271/58 ,  C07D207/46 ,  C07D213/40 ,  C07D401/12 ,  G01N1/405 ,  G01N27/62 ,  G01N30/06 ,  G01N30/7233

摘要： Enantiomers may be analyzed by: (1) reacting a mixture of a first compound and a second compound that are a pair of enantiomers with an axially chiral compound that is one of a pair of axially chiral isomers, to generate a derivative mixture containing a first derivative obtained by a reaction of the first compound with the axially chiral compound and a second derivative obtained by a reaction of the second compound with the axially chiral compound; (2) separating the first derivative and the second derivative in the derivative mixture; and (3) detecting the separated first derivative and second derivative by mass spectrometry.

公开(公告)号：US20180209945A1

公开(公告)日：2018-07-26

申请号：US15745841

申请日：2016-12-28

申请人： AiSTI SCIENCE CO., Ltd.

发明人： Ryoichi SASANO

IPC分类号： G01N30/06 ,  B01D11/02 ,  B01D15/36 ,  G01N30/96

CPC分类号： G01N30/06 ,  B01D11/0288 ,  B01D15/362 ,  B01D15/363 ,  G01N1/10 ,  G01N1/34 ,  G01N1/405 ,  G01N1/4055 ,  G01N30/88 ,  G01N30/96 ,  G01N2030/025 ,  G01N2030/027 ,  G01N2030/067

摘要： A pre-analysis treatment method includes: a first retaining step of supplying, to a solid phase, each predetermined amount of the sample and a first solvent, and allowing a component at low concentration to be retained in the solid phase; a first washing step of supplying the first solvent to the solid phase and removing a component at high concentration from the solid phase; a second retaining step of supplying the sample in a smaller amount than the predetermined amount supplied in the first retaining step, and a second solvent to the solid phase, and allowing the component at high concentration to be retained in the solid phase; and an elution step of simultaneously extruding the components retained in the solid phase with an extrusion solvent.

公开(公告)号：US10018602B2

公开(公告)日：2018-07-10

申请号：US15032394

申请日：2014-10-27

申请人： SHIMADZU CORPORATION ,  AICHI PREFECTURAL GOVERNMENT

发明人： Eiji Ueno ,  Riki Kitano ,  Haruhiko Miyagawa

IPC分类号： G01N30/06 ,  G01N30/88 ,  G01N30/86 ,  B01J20/281 ,  B01J20/283 ,  G01N30/72 ,  G01N30/00

CPC分类号： G01N30/06 ,  B01J20/283 ,  B01J2220/54 ,  G01N30/48 ,  G01N30/7206 ,  G01N30/8665 ,  G01N30/88 ,  G01N2030/486

摘要： A number of analytes are divided into groups based on at least either the elution position determined by silica gel column chromatography under the same condition or the partition ratio in a hexane-acetonitrile partition method. To each group, a compound obtained by labeling one of the compounds in the group by deuterium and/or carbon is assigned as the surrogate. After those surrogates are added as internal standard substances to a standard sample for the creation of calibration curves, a GC/MS analysis for the sample is performed and a calibration curve is created for each analyte. In the measurement of an unknown sample, the same set of surrogates are added to the sample and the GC/MS analysis is performed. A quantitative determination processor determines the quantity of each analyte by comparing a peak area ratio calculated from the analysis result with a calibration curve read from the database.

公开(公告)号：US20180164275A1

公开(公告)日：2018-06-14

申请号：US15570030

申请日：2016-04-29

申请人： Avraham Arthur KOMILOSH ,  Dalia PINKERT

发明人： Avraham Arthur KOMILOSH ,  Dalia PINKERT

IPC分类号： G01N33/44 ,  C08G69/10 ,  G01N21/47 ,  G01N30/89 ,  G01N30/06 ,  C08G69/46

CPC分类号： G01N33/442 ,  C08G69/10 ,  C08G69/46 ,  G01N21/47 ,  G01N30/06 ,  G01N30/74 ,  G01N30/89 ,  G01N33/68 ,  G01N2021/4711

摘要： The present invention provides a process for characterizing a glatiramer acetate, related drug substance (GARDS) or a glatiramer acetate related drug product (GARDP) comprising separating a batch of a GARDS or GARDP according to hydrophobicity and determining the molar mass of the separated material, thereby characterizing the GARDS or GARDP by molar mass as a function of hydrophobicity.

公开(公告)号：US09995663B2

公开(公告)日：2018-06-12

申请号：US14914995

申请日：2014-08-29

申请人： Biotage AB

发明人： Alan Edgington ,  Lee Williams

IPC分类号： G01N1/40 ,  B01D11/02 ,  G01N33/02 ,  G01N33/10 ,  G01N33/14 ,  G01N30/06

CPC分类号： G01N1/405 ,  B01D11/02 ,  G01N1/4055 ,  G01N33/02 ,  G01N33/025 ,  G01N33/10 ,  G01N33/14 ,  G01N2001/4061 ,  G01N2030/062

摘要： The present invention relates to a method for extracting acrylamide from a matrix comprising matrix components and acrylamide, comprising the steps: bringing said matrix in contact with water to obtain an aqueous extract, and, optionally, adding a base to the aqueous extract; loading a portion of the aqueous extract obtained in the previous step onto an inert support; allowing the inert support to absorb the aqueous extract; extracting acrylamide from the aqueous extract by passing a water immiscible organic solvent through the inert support; thereby obtaining an organic extract. It further relates to a method for analyzing acrylamide content in a matrix comprising matrix components and acrylamide.

公开(公告)号：US20180143212A1

公开(公告)日：2018-05-24

申请号：US15539344

申请日：2015-12-23

申请人： Biotech Institute, LLC

发明人： Matthew W. Giese ,  Mark Anthony Lewis ,  Laura Giese

IPC分类号： G01N33/94 ,  G01N30/68 ,  B01D15/08 ,  B01D53/02 ,  G01N21/3554 ,  G01N30/06 ,  B01D11/02 ,  G01N21/35 ,  G01N30/02

CPC分类号： G01N33/948 ,  A61K36/185 ,  A61K2236/00 ,  B01D11/0288 ,  B01D15/08 ,  B01D53/025 ,  G01N21/3554 ,  G01N30/06 ,  G01N30/68 ,  G01N2021/3595 ,  G01N2030/025 ,  G01N2030/027 ,  G01N2030/042 ,  G01N2333/415 ,  G01N2407/00

摘要： The present invention teaches methods useful for accurately and precisely analyzing cannabis plants, plant parts, and extract samples. In particular, the present invention teaches methods of extracting, and quantifying cannabinoid and terpene constituents.

公开(公告)号：US09945821B2

公开(公告)日：2018-04-17

申请号：US14804846

申请日：2015-07-21

申请人： SGS North America Inc.

发明人： Wayne A. Kriel ,  Sven Lataire

IPC分类号： G01N1/16 ,  G01N30/28 ,  G01N1/24 ,  G01N1/22 ,  G01N30/06 ,  G01N33/22 ,  G01N30/02 ,  G01N1/10

CPC分类号： G01N30/28 ,  G01N1/22 ,  G01N1/2247 ,  G01N1/24 ,  G01N30/06 ,  G01N33/225 ,  G01N2001/105 ,  G01N2001/1093 ,  G01N2030/025

摘要： Composite sampling of a fluid flowing through a conduit includes collecting, in a vessel coupled to the conduit through which the fluid is flowing, a first discrete sample of fluid from the conduit, the first discrete sample having a first selected volume, and collecting, in the vessel and at a first interval from the first sample, a second discrete sample of the fluid from the conduit, the second discrete sample having a second selected volume, thereby forming a composite sample in the vessel while the vessel is coupled to conduit. The composite sample includes the first discrete sample and the second discrete sample, and may include one or more additional discrete samples. An apparatus for collecting the composite sample includes a gas chromatograph, and is arranged such that the composite sample is provided to the gas chromatograph without removing the composite sample from the apparatus or transporting the composite sample.

公开(公告)号：US09927333B2

公开(公告)日：2018-03-27

申请号：US13700709

申请日：2011-05-24

申请人： Patrick Sandra ,  Bart Tienpont ,  Frank David ,  Tom Sandra ,  Koen Sandra

发明人： Patrick Sandra ,  Bart Tienpont ,  Frank David ,  Tom Sandra ,  Koen Sandra

IPC分类号： G01N1/34 ,  G01N30/06 ,  G01N30/18 ,  B01D15/12 ,  G01N1/02 ,  G01N30/12

CPC分类号： G01N1/34 ,  B01D15/12 ,  G01N1/02 ,  G01N30/06 ,  G01N30/18 ,  G01N2030/125 ,  Y10T436/25125

摘要： The invention relates to a method for preparing a sample for chromatographic separation processes, in which a sample vessel (1) is partially filled with a substance to be examined and is closed, the substance to be examined is subjected to a thermo-chemical reaction in which at least one sample component is converted into another substance, and in which by means of a removing device samples are removed from the sample vessel (1) for analytical examination, characterized in that the sample vessel (1) forms a cavity, into which the substance to be examined is introduced as a core and a heating section for indirect heat transfer is applied along the filling of substance to be examined.