公开(公告)号：US20250002834A1

公开(公告)日：2025-01-02

申请号：US18709715

申请日：2023-02-08

Applicant: MERCK PATENT GMBH

Inventor： Laurent Jourdainne ,  Thomas Coton ,  Anthony Da Silva ,  Quentin Spindler

IPC: C12M1/00 ,  C12M1/02 ,  C12M1/34 ,  G01N30/46 ,  G01N30/64

Abstract: A pH system that is able to compensate for variations in pressure and conductivity is disclosed. The system includes a pH sensor, a pressure sensor and optionally a conductivity sensor, the outputs of each are transmitted to a controller. The controller multiplies a compensation coefficient by the difference in pressure between the measured pressure and a threshold pressure. This result is then added to the measured pH value. Further, the compensation coefficient is a function of the conductivity of the solution. In some instances, the compensation coefficient is calculated by raising the conductivity to a power and multiplying that result by a constant. This pH system may be incorporated into various bioprocessing systems, such as multi-column chromatography systems and viral inactivation systems.

公开(公告)号：US12158453B2

公开(公告)日：2024-12-03

申请号：US17430915

申请日：2020-02-24

Applicant: Cytiva Sweden AB

Inventor： Lars Mattsson ,  Ioana Erlandsson ,  Therese Westman ,  Enrique Carredano ,  Jenny Dunker

IPC: G01N30/34 ,  G01N30/02 ,  G01N30/32 ,  G01N30/64 ,  G01N30/74 ,  G01N30/88

Abstract: The present invention relates to a computer-implemented method for controlling preparation of a liquid mixture comprising an acid and its conjugate base or a base and its conjugate acid. The method comprises obtaining (S11) a composition for the liquid mixture to be prepared and determining (S12) a plurality of settings for controlling a preparation of the liquid mixture in one or more automated processes. The plurality of settings are provided (S13) to one or more control systems of the one or more automated processes. The present invention also relates to a buffer tool configured to perform the computer-implemented method, a buffer management system comprising the buffer tool, and a computer readable storage medium (25), having stored thereon a computer program which, when executed in a buffer tool, causes execution of the computer-implemented method.

公开(公告)号：US20240353378A1

公开(公告)日：2024-10-24

申请号：US18761191

申请日：2024-07-01

Applicant: PETROCHINA COMPANY LIMITED

Inventor： Li ZHOU ,  Xiaoqin WANG ,  Wenping ZENG ,  Lin SHEN

IPC: G01N30/20 ,  B01D53/02 ,  G01N30/02 ,  G01N30/14 ,  G01N30/64 ,  G01N30/74 ,  G01N30/78 ,  G01N33/00

CPC classification number: G01N30/20 ,  B01D53/025 ,  G01N30/14 ,  G01N30/64 ,  G01N30/74 ,  G01N30/78 ,  G01N33/0027 ,  B01D2257/102 ,  B01D2257/104 ,  B01D2257/108 ,  B01D2257/11 ,  B01D2257/30 ,  B01D2257/502 ,  B01D2257/504 ,  B01D2257/7025 ,  G01N2030/025

Abstract: The present invention provides a device and method for analyzing quality indicators of a natural gas product and an application. The device comprises a sample loading assembly, and first, second, third, fourth, and fifth chromatographic column analysis systems connected in parallel, wherein the first chromatographic column analysis system is configured for separating sulfides from natural gas; the second chromatographic column analysis system is configured for separating hydrocarbons having C3 and higher from the natural gas; the third chromatographic column analysis system is configured for separating oxygen, nitrogen, methane, and carbon monoxide from the natural gas; the fourth chromatographic column analysis system is configured for separating carbon dioxide and ethane from the natural gas; and the fifth chromatographic column analysis system is configured for separating helium and hydrogen from the natural gas; each chromatographic column analysis system is provided with a quantitative tube, a carrier gas tube, and a chromatographic column.

公开(公告)号：US12085544B2

公开(公告)日：2024-09-10

申请号：US17498203

申请日：2021-10-11

Applicant: Srivatsan Mohana Rangan ,  Anca Delgado ,  Rosa Krajmalnik-Brown

Inventor： Srivatsan Mohana Rangan ,  Anca Delgado ,  Rosa Krajmalnik-Brown

IPC: G01N30/54 ,  G01N30/64 ,  G01N30/86 ,  G01N33/18

CPC classification number: G01N30/54 ,  G01N30/64 ,  G01N30/8679 ,  G01N33/182

Abstract: Methods and systems for the detection and quantification of multiplicity of ionic analytes comprising CrO42−, AsO43−, SeO42−, and ClO4−, and optionally F−, Cl−, NO2−, NO3−, SO42−, using ion chromatography and suppressed ion conductivity. The method comprises loading a sample loop with a sample; injecting the sample from the sample loop into a column with an eluent, wherein the column comprises a guard column and an analytical column; separating, with the column, the injected sample at an effective separation temperature the injected sample in the presence of an organic modifier into a multiplicity of detectable ionic analytes; suppressing, with a suppressor, background signal; and detecting, with a detector, the multiplicity of ionic analytes.

公开(公告)号：US20240201146A1

公开(公告)日：2024-06-20

申请号：US18068246

申请日：2022-12-19

Applicant: Dionex Corporation

Inventor： Jun Cheng ,  Yan Liu ,  Gary L. Gleave

IPC: G01N30/64

CPC classification number: G01N30/64 ,  G01N2030/027

Abstract: The present invention relates to, in general, a disposable electrically insulating substrate surface comprising a platinum hydrogen reference electrode system structure, the use of such a substrate in a flow-through electrochemical cell assembly and methods of manufacturing said substrate. For example, in some embodiments, a disposable electrically insulating substrate surface comprising a platinum hydrogen reference electrode system structure, wherein the platinum hydrogen reference electrode system comprises an electrically conductive and electrochemically active platinum hydrogen reference electrode system region bound as a layer, directly or indirectly, to said substrate surface.

公开(公告)号：US12013381B2

公开(公告)日：2024-06-18

申请号：US17167383

申请日：2021-02-04

Applicant: FRONTIER LABORATORIES LTD.

Inventor： Chuichi Watanabe ,  Atsushi Watanabe ,  Koji Tei

IPC: G01N30/68 ,  G01N30/46 ,  G01N30/60 ,  G01N30/78 ,  G01N30/88 ,  G01N30/00 ,  G01N30/02 ,  G01N30/06 ,  G01N30/64

CPC classification number: G01N30/68 ,  G01N30/466 ,  G01N30/6034 ,  G01N30/6095 ,  G01N30/78 ,  G01N30/88 ,  G01N2030/0095 ,  G01N2030/025 ,  G01N2030/062 ,  G01N2030/642 ,  G01N2030/8881

Abstract: A gas phase component analysis device and a gas phase component analysis method that can prevent degradation of the device due to an unnecessary component and can obtain excellent detection sensitivity are provided.
A gas phase component analysis device (1) includes a heating unit (2) configured to heat a specimen to generate a gas phase component composite, a first column (31) into which the gas phase component composite is introduced, a second column (32) that is a separation column connected with the first column (31) through a connection unit (33), an isothermal oven (3) housing the first column (31), the second column (32), and the connection unit (33), a detection unit (4) configured to detect a gas phase component having passed through the second column (32), and a suction unit (5) connected with the connection unit (33).

公开(公告)号：US11977059B2

公开(公告)日：2024-05-07

申请号：US17479410

申请日：2021-09-20

Applicant: SHIMADZU CORPORATION ,  Osaka University

Inventor： Kei Shinada ,  Satoshi Matsuoka ,  Katsuhisa Kitano

IPC: G01N27/66 ,  G01N27/70 ,  G01N30/64 ,  G01N30/02

CPC classification number: G01N30/64 ,  G01N27/70 ,  G01N2030/025

Abstract: A light source emits excitation light to discharge gas that flows through a dielectric tube. A ground electrode unit includes a first ground electrode and a second ground electrode arranged at a distance from each other in an axial direction of the dielectric tube. A high-voltage electrode is provided between the first ground electrode and the second ground electrode. A first distance between the first ground electrode and the high-voltage electrode is shorter than a second distance between the second ground electrode and the high-voltage electrode. A cover is provided on an outer wall of the dielectric tube at a position between the first ground electrode and the high-voltage electrode. The light source is arranged to emit excitation light such that an optical axis thereof is directed toward a position where the cover is not provided on the outer wall of the dielectric tube.

公开(公告)号：US11796525B2

公开(公告)日：2023-10-24

申请号：US17056425

申请日：2018-08-29

Applicant: TONGJI UNIVERSITY

Inventor： Lei Li ,  Wenjun Zhang ,  Shichong Wang

IPC: G01N33/18 ,  G01N21/78 ,  G01N30/04 ,  G01N30/64 ,  G01N30/88 ,  G01N30/14

CPC classification number: G01N33/182 ,  G01N21/78 ,  G01N30/14 ,  G01N30/64 ,  G01N30/88 ,  G01N33/1846 ,  G01N2030/645 ,  G01N2030/884

Abstract: An instrument and a method for simultaneously testing a molecular weight distribution and an organic nitrogen level of a water sample are provided. The instrument comprises: a tail-end injection valve, a chromatographic column, a pressure relief valve, an acid-adding injection valve, an oxygen-adding injection valve, a helical tube for an acid-oxygen reaction, a CO2 remover, a UV digester, a second gas-water separator membrane, a buffer solution injection valve, a helical tube for a buffer solution reaction, a cadmium column, a chromogenic agent injection valve, a helical tube for a chromogenic agent reaction, and a UV detector, sequentially connected via a pipeline. The tail-end injection valve is for receiving a fluid phase and a sample. The second gas-water separator membrane is connected to an electrical conductivity-based CO2 detector. The UV detector and the electrical conductivity-based CO2 detector are connected to a data processing computer.

公开(公告)号：US11572339B2

公开(公告)日：2023-02-07

申请号：US17569872

申请日：2022-01-06

Applicant: NOVEN PHARMACEUTICALS, INC.

Inventor： Deboprosad Mondal

IPC: C07C269/08 ,  G01N30/06 ,  G01N30/64 ,  G01N30/02

Abstract: Described herein are the amphetamine-related compounds amphetamine carbamate (amphetammonium-amphetacarbamate) and amphetacarbamate, methods of making them, methods for detecting or quantitatively determining the amount of amphetacarbamate or amphetamine carbamate in a compositions, and ion chromatography columns useful in such methods.

公开(公告)号：US11558952B2

公开(公告)日：2023-01-17

申请号：US16712259

申请日：2019-12-12

Applicant: Shimadzu Corporation ,  OSAKA UNIVERSITY

Inventor： Kei Shinada ,  Katsuhisa Kitano

IPC: H05H1/24 ,  G01N30/64 ,  G01N30/02

Abstract: A BID includes: a discharger (2) including a dielectric pipe (8) and a pair of electrodes (14, 16) attached on an outer wall of the dielectric pipe, the pair of electrodes (14, 16) being arranged at a distance from each other in a direction along a central axis of the dielectric pipe (8), the discharger (2) being arranged so that plasma generating gas is introduced from a first end of the dielectric pipe (8) and configured to generates dielectric barrier discharge inside the dielectric pipe (8) to generate plasma; a detection section (4) including a sample gas introduction section (31) and a collection electrode (26) for collecting ions, the detection section (4) being configured to ionize components in the sample gas using light emitted from the plasma generated in the discharger (2) and to detect the generated ions by collecting them using the collection electrode (26); and a voltage supply (6; 6′) for generating a potential difference between the pair of electrodes (14, 16).