公开(公告)号：US20240310335A1

公开(公告)日：2024-09-19

申请号：US18218279

申请日：2023-07-05

申请人： KING FAISAL UNIVERSITY

发明人： AMEL YOUSIF IBRAHIM ,  IMENE BAYACH

IPC分类号： G01N30/06 ,  B01D11/02 ,  C07D307/62

CPC分类号： G01N30/06 ,  B01D11/0288 ,  C07D307/62 ,  G01N2030/062

摘要： A method of extracting at least one vitamin from Commiphora myrrha selected from vitamin B1 (thiamin) and vitamin C (ascorbic acid) includes contacting a dried Commiphora myrrha resin with an extracting solvent to obtain an extract including the at least one vitamin. A vitamin selected from Vitamin B1 and Vitamin C from the extract can be isolated from the extract using high liquid performance chromatography (HPLC).

公开(公告)号：US20240302334A1

公开(公告)日：2024-09-12

申请号：US18599970

申请日：2024-03-08

申请人： Waters Technologies Corporation

发明人： Jinchuan Yang ,  Paul Rainville

IPC分类号： G01N30/56 ,  G01N30/04 ,  G01N30/06 ,  G01N30/72 ,  G01N30/74

CPC分类号： G01N30/56 ,  G01N30/06 ,  G01N30/7233 ,  G01N30/74 ,  G01N2030/045 ,  G01N2030/567

摘要： The present disclosure is directed to methods of separating one or more non-modified oligosaccharide(s) with degree of polymerization 6 or higher from a sample using a hydrophilic interaction liquid chromatography (HILIC) column connected to a liquid chromatography system that includes coated flow paths. The methods disclosed herein requires, inter alia, a liquid chromatography system, wherein at least one component of the LC system includes a fluid-contacting alkylsilyl coating. When implementing a standard HILIC method, the methods of the present technology can be used to decrease the analyte loss and/or carry-over of the separation leading to improved analysis.

公开(公告)号：US12061180B2

公开(公告)日：2024-08-13

申请号：US18063128

申请日：2022-12-08

申请人： Alexander Bozic

发明人： Alexander Bozic

IPC分类号： G01N30/84 ,  B01D15/40 ,  B01D45/08 ,  G01N30/06 ,  G01N30/80

CPC分类号： G01N30/84 ,  B01D15/40 ,  B01D45/08 ,  G01N30/06 ,  G01N2030/065 ,  G01N30/80

摘要： The present invention relates to a gas-liquid separator for a chromatography system, comprising:



(a) a separating region having an inlet nozzle, a baffle unit and a gas distribution unit;
(b) a dividing region having a liquid outlet; and
(c) a gas discharge region having a gas outlet;
wherein the separating region is connected to the dividing region by a separating opening and the distance of the inlet nozzle from the baffle unit is greater than the smallest longitudinal extension of the separating opening and the inlet nozzle is configured such that a gas-liquid stream directed through the inlet nozzle can act on the baffle unit.




The present invention further relates to a chromatography system comprising a separator according to the invention and to a chromatography method wherein the separator is used.

公开(公告)号：US12050208B2

公开(公告)日：2024-07-30

申请号：US17510745

申请日：2021-10-26

申请人： Shimadzu Corporation ,  National University Corporation, Iwate University

发明人： Junichi Kita ,  Masao Miyazaki ,  Motoo Kinoshita

IPC分类号： G01N33/00 ,  G01N30/06 ,  G01N30/02 ,  G01N30/88

CPC分类号： G01N30/06 ,  G01N33/0001 ,  G01N33/0018 ,  G01N2030/025 ,  G01N2030/062 ,  G01N2030/8868

摘要： An odor evaluation device, including: a gas chromatograph including a separation column configured to temporally separate a plurality of components contained in an odoriferous analysis-target gas; a timing detector configured to detect, for each of the plurality of components, a timing at which the component exits from the separation column; a gas collector configured to collect, into a sample bag, a gas containing all or some of the components exiting from the separation column when the analysis-target gas is passed through the separation column; a timing setter configured to allow a setting of a timing at which a component contained in the gas to be collected into the sample bag exits from the separation column; and a gas introducer configured to introduce a dilution gas into a passage connecting the separation column and the sample bag.

公开(公告)号：US12038418B2

公开(公告)日：2024-07-16

申请号：US16933663

申请日：2020-07-20

申请人： Baker Hughes Oilfield Operations LLC

发明人： Salar Azizi ,  Nicklas Ritzmann

IPC分类号： G01N30/00 ,  E21B49/08 ,  G01N30/06 ,  G01N30/40 ,  G01N30/02 ,  G01N30/20

CPC分类号： G01N30/40 ,  E21B49/088 ,  G01N30/06 ,  G01N2030/025 ,  G01N2030/062 ,  G01N2030/201 ,  G01N2030/402

摘要： One or more embodiments of the present disclosure include a gas-analysis system. The gas-analysis system may include a first valve, a gas-measurement device, and a second valve. The first valve may be between a sample-gas line and a sample-gas outlet. The first valve may be configured to either allow or prevent gas movement between the sample-gas line and the sample-gas outlet. The gas-measurement device operatively coupled to a testing-gas line. The second valve may be between the sample-gas line, a flushing-gas inlet, and the testing-gas line. The second valve may be configured to allow gas movement from one of the sample-gas line or the flushing-gas inlet to the testing-gas line.

公开(公告)号：US20240230607A9

公开(公告)日：2024-07-11

申请号：US18381605

申请日：2024-01-14

申请人： SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY

发明人： Chengyuan LIANG ,  Changhua KE ,  Yanzi WANG ,  Yuting LIU ,  Xiuding YANG ,  Ying ZHOU ,  Jiaxuan LI

IPC分类号： G01N30/86 ,  G01N1/28 ,  G01N30/02 ,  G01N30/06 ,  G01N30/74

CPC分类号： G01N30/8686 ,  G01N30/74 ,  G01N30/8631 ,  G01N2001/2893 ,  G01N2030/027 ,  G01N2030/062

摘要： A fingerprint spectrum construction method for Xihuang capsules and a fingerprint spectrum includes: S1: taking contents of a Xihuang capsule, adding a methanol-chloroform-phosphoric acid solution, and carrying out ultrasonic extraction to obtain a Xihuang capsule test solution; S2: dissolving cholic acid, hyodeoxycholic acid, deoxycholic acid, bilirubin, muscone, and myrrhone in ethanol to obtain a mixed standard solution 1; dissolving quassin, 11-carbonyl-β-boswellic acid, 11-carbonyl-β-acetyl-boswellic acid, acetyl-11α-methoxy-β-boswellic acid, and sandaracopimaric acid in methanol to obtain a mixed standard solution 2; S3: respectively carrying out chromatography on the Xihuang capsule test solution and the mixed standard solutions 1 and 2, and recording corresponding chromatograms; and S4: constructing a fingerprint spectrum of the Xihuang capsule according to the chromatogram of the Xihuang capsule test solution and the chromatograms of the mixed standard solutions 1 and 2. The method can accurately, clearly and objectively evaluate the quality of Xihuang capsules.

公开(公告)号：US12031962B2

公开(公告)日：2024-07-09

申请号：US16438797

申请日：2019-06-12

申请人： Roche Diagnostics Operations, Inc.

发明人： Dieter Heindl ,  Thomas Heinemeyer ,  Uwe Kobold ,  Martin Rempt ,  Christoph Seidel

IPC分类号： G01N30/46 ,  G01N30/02 ,  G01N30/06 ,  G01N30/28 ,  G01N30/72 ,  G01N33/58

CPC分类号： G01N30/466 ,  G01N30/06 ,  G01N30/28 ,  G01N30/7233 ,  G01N33/58 ,  G01N2030/027 ,  G01N2030/067

摘要： A method for identifying a reagent during a process in an analysis system is disclosed. The analysis system comprises a liquid chromatograph and a mass spectrometer. The method comprises providing a reagent, adding at least one chemical substance to the reagent with a concentration being above a detection level of the mass spectrometer, processing the reagent together with the chemical substance with the analysis system, and identifying the reagent based on a detection of a substance detection signal of the mass spectrometer representing the chemical substance.

公开(公告)号：US12025631B2

公开(公告)日：2024-07-02

申请号：US17059859

申请日：2018-05-28

申请人： SHIMADZU CORPORATION

发明人： Takashi Inoue ,  Makoto Ogaito

IPC分类号： G01N35/10 ,  B01D15/14 ,  B01F33/30 ,  B01F101/23 ,  G01N30/06 ,  G01N30/18 ,  G01N30/24

CPC分类号： G01N35/1095 ,  B01D15/14 ,  B01F33/30 ,  G01N30/06 ,  G01N30/18 ,  G01N30/24 ,  B01F2101/23 ,  G01N2030/067

摘要： An automatic sample introduction device includes a needle, a sample loop, a mixer and a suction injection switch mechanism. The mixer is provided between the needle and the sample loop. The suction injection switch mechanism sequentially sucks first and second fluids into the sample loop through the needle and the mixer and injects the first and second fluids held in the sample loop into a predetermined injection port. A chromatograph includes the automatic sample introduction device having the above-mentioned configuration, an analysis column and a detector. The analysis column is connected to the injection port of the automatic sample introduction device, and the detector is connected to the analysis column.

公开(公告)号：US20240210362A1

公开(公告)日：2024-06-27

申请号：US18596638

申请日：2024-03-06

申请人： ShenZhen BayOmics Biotechnology Co., Ltd.

发明人： Ruijun TIAN ,  Wendong CHEN

IPC分类号： G01N30/06 ,  C07K1/36 ,  G01N30/60 ,  G01N30/89 ,  G01N33/68

CPC分类号： G01N30/06 ,  C07K1/36 ,  G01N30/6078 ,  G01N30/89 ,  G01N33/6842 ,  G01N2030/065

摘要： Disclosed is a proteomic reactor, comprising a pipette tip, an ion exchange resin filler and a solid-phase extraction membrane. The solid-phase extraction membrane is filled into the lower end of the pipette tip, and the ion exchange resin is filled into the lower end of the pipette tip and is located above the solid-phase extraction membrane. The ion exchange resin is a strong cation exchange resin or a strong anion exchange resin. Disclosed is a protein chromatographic separation platform comprising the proteomic reactor and a liquid chromatography-mass spectrometer. Disclosed is the use of the proteomic reactor and protein chromatographic separation platform in the protein identification and protein quantitative analysis of a cell, a tissue or a blood sample.

公开(公告)号：US20240183827A1

公开(公告)日：2024-06-06

申请号：US17795532

申请日：2022-03-30

申请人： REMEGEN CO., LTD

发明人： Xuejing YAO ,  Fangfang SUN ,  Wenlong SUN ,  Guiping QI

IPC分类号： G01N30/72 ,  B01D15/10 ,  G01N30/02 ,  G01N30/06

CPC分类号： G01N30/7233 ,  B01D15/10 ,  G01N30/06 ,  G01N2030/027

摘要： The present disclosure relates to a method for detecting DTPA content in ADC by LC-MS/MS. The samples are derivatized with Fe3+ under a weak alkaline derivatization condition, and a weak alkaline mobile phase is used, without need for addition of ion-pair reagents. This method has the characteristics of high efficiency, high stability and strong durability, and can well make up for the defects of few DTPA detection methods and complicated operations in the prior art.