-
公开(公告)号：US11885818B2
公开(公告)日：2024-01-30
申请号：US17155054
申请日：2021-01-21
发明人： Dieter Heindl , Hans-Peter Josel , Uwe Kobold , Christoph Seidel , Martin Rempt , Andreas Leinenbach , Giuseppe Prencipe , Silvia Baecher , Simon Ferdinand Loibl , Anna-Skrollan Geiermann , Jelena Milic , Nicole Pirkl
IPC分类号： C07D401/06 , C07D413/06 , G01N33/74 , G01N33/58 , C07J43/00
CPC分类号： G01N33/743 , C07D401/06 , C07D413/06 , C07J43/003 , G01N33/58 , G01N2560/00
摘要： The present invention relates to reagents which are suitable to be used in mass spectrometry as well as methods of mass spectrometric determination of analyte molecules using said reagents.
-
公开(公告)号：US09499573B2
公开(公告)日：2016-11-22
申请号：US14610244
申请日：2015-01-30
发明人： Frank Bergmann , Robert Cysewski , Luisa de Cola , Sebastian Dziadek , Jesus Miguel Fernandez Hernandez , Hans-Peter Josel , Elena Longhi , Christoph Seidel
CPC分类号： C07F15/0033 , C09K11/06 , C09K2211/1007 , C09K2211/1029 , C09K2211/1059 , C09K2211/14 , C09K2211/1416 , C09K2211/1425 , C09K2211/1441 , C09K2211/1466 , C09K2211/1475 , C09K2211/1491 , C09K2211/185 , G01N33/582 , G01N2458/30
摘要： The present invention relates to novel iridium-based Ir(III) luminescent complexes, conjugates comprising these complexes as a label and their application, e.g. in the electrochemiluminescence based detection of an analyte.
-
公开(公告)号：US20150147752A1
公开(公告)日：2015-05-28
申请号：US14610244
申请日：2015-01-30
发明人： Frank Bergmann , Robert Cysewski , Luisa de Cola , Sebastian Dziadek , Jesus Miguel Fernandez Hernandez , Hans-Peter Josel , Elena Longhi , Christoph Seidel
CPC分类号： C07F15/0033 , C09K11/06 , C09K2211/1007 , C09K2211/1029 , C09K2211/1059 , C09K2211/14 , C09K2211/1416 , C09K2211/1425 , C09K2211/1441 , C09K2211/1466 , C09K2211/1475 , C09K2211/1491 , C09K2211/185 , G01N33/582 , G01N2458/30
摘要： The present invention relates to novel iridium-based Ir(III) luminescent complexes, conjugates comprising these complexes as a label and their application, e.g. in the electrochemiluminescence based detection of an analyte.
-
公开(公告)号：US20240092742A1
公开(公告)日：2024-03-21
申请号：US18500149
申请日：2023-11-02
发明人： Dieter Heindl , Hans-Peter Josel , Uwe Kobold , Christoph Seidel , Martin Rempt , Andreas Leinenbach , Giuseppe Prencipe , Silvia Baecher , Simon Ferdinand Loibl , Anna-Skrollan Geiermann , Jelena Milic , Nicole Pirkl
IPC分类号： C07D249/06 , C07D203/04 , C07D249/04 , C07D257/04 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/06 , C07D471/04
CPC分类号： C07D249/06 , C07D203/04 , C07D249/04 , C07D257/04 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/06 , C07D471/04 , G01N30/72
摘要： The present invention relates to reagents which are suitable to be used in mass spectrometry as well as methods of mass spectrometric determination of analyte molecules using said reagents.
-
公开(公告)号：US20210188788A1
公开(公告)日：2021-06-24
申请号：US17154501
申请日：2021-01-21
发明人： Dieter Heindl , Hans-Peter Josel , Uwe Kobold , Christoph Seidel , Martin Rempt , Andreas Leinenbach , Giuseppe Prencipe , Silvia Baecher , Simon Ferdinand Loibl , Anna-Skrollan Geiermann , Jelena Milic , Robert Hahn , Nicole Pirkl
IPC分类号： C07D257/04 , C07D249/06 , H01J49/00
摘要： The present invention relates to reagents which are suitable to be used in mass spectrometry as well as methods of mass spectrometric determination of analyte molecules using said reagents.
-
公开(公告)号：US20150147750A1
公开(公告)日：2015-05-28
申请号：US14609552
申请日：2015-01-30
发明人： Frank Bergmann , Robert Cysewski , Luisa de Cola , Sebastian Dziadek , Jesus Miguel Fernandez Hernandez , Hans-Peter Josel , Christoph Seidel
CPC分类号： C07F15/0033 , C09K11/06 , C09K11/07 , C09K2211/1003 , C09K2211/1007 , C09K2211/1011 , C09K2211/1029 , C09K2211/1059 , C09K2211/1074 , C09K2211/14 , C09K2211/185 , G01N33/582
摘要： The present invention relates to novel iridium-based Ir(III) luminescent complexes, conjugates comprising these complexes as a label and their application, e.g. in the electrochemiluminescence based detection of an analyte.
-
公开(公告)号：US20130289251A1
公开(公告)日：2013-10-31
申请号：US13923631
申请日：2013-06-21
IPC分类号： C07K19/00
CPC分类号： C07K19/00 , C07K16/18 , C07K16/2863 , C07K16/32 , C07K2317/31 , C07K2317/34 , C07K2317/55 , C07K2317/626 , C07K2317/92 , C07K2317/94
摘要： A binding agent of the Formula A-a′:a-S-b:b′-B:X(n), wherein A as well as B is a monovalent binder, a′:a as well as b:b′ is a binding pair wherein a′ and a do not interfere with the binding of b to b′ and vice versa, S is a spacer of at least 1 nm in length, :X denotes a functional moiety bound either covalently or via a binding pair to at least one of a′, a, b, b′ or S, (n) is an integer and at least 1, - represents a covalent bond, and the linker a-S-b has a length of 6 to 100 nm. Also disclosed are methods of producing such binding agent and certain uses thereof.
摘要翻译： 式A-a'：aSb：b'-B：X（n）的结合剂，其中A以及B是单价键合物，a：a以及b：b'是结合对，其中 a'和a不干扰b与b'的结合，反之亦然，S是长度至少为1nm的间隔物：X表示与共价键或通过结合对键合到至少一个 a'，a，b，b'或S，（n）为整数且至少为1， - 表示共价键，连接体aSb的长度为6〜100nm。 还公开了生产这种结合剂及其某些用途的方法。
-
公开(公告)号：US12031962B2
公开(公告)日：2024-07-09
申请号：US16438797
申请日：2019-06-12
发明人： Dieter Heindl , Thomas Heinemeyer , Uwe Kobold , Martin Rempt , Christoph Seidel
CPC分类号： G01N30/466 , G01N30/06 , G01N30/28 , G01N30/7233 , G01N33/58 , G01N2030/027 , G01N2030/067
摘要： A method for identifying a reagent during a process in an analysis system is disclosed. The analysis system comprises a liquid chromatograph and a mass spectrometer. The method comprises providing a reagent, adding at least one chemical substance to the reagent with a concentration being above a detection level of the mass spectrometer, processing the reagent together with the chemical substance with the analysis system, and identifying the reagent based on a detection of a substance detection signal of the mass spectrometer representing the chemical substance.
-
公开(公告)号：US20210198217A1
公开(公告)日：2021-07-01
申请号：US17155020
申请日：2021-01-21
发明人： Dieter Heindl , Hans-Peter Josel , Uwe Kobold , Christoph Seidel , Martin Rempt , Andreas Leinenbach , Giuseppe Prencipe , Silvia Baecher , Simon Ferdinand Loibl , Anna-Skrollan Geiermann , Jelena Milic , Nicole Pirkl
IPC分类号： C07D249/06 , C07D257/04 , C07D203/04 , G01N30/72
摘要： The present invention relates to reagents which are suitable to be used in mass spectrometry as well as methods of mass spectrometric determination of analyte molecules using said reagents.
-
公开(公告)号：US20190309091A1
公开(公告)日：2019-10-10
申请号：US16450186
申请日：2019-06-24
发明人： Michael Gerg , Lars Hillringhaus , Klaus Hirzel , Caroline Dorothea Hojer , Hans-Peter Josel , Christoph Seidel , Michael Schraeml , Leopold Von Proff
IPC分类号： C07K16/44 , G01N33/543
摘要： The present invention relates to a monoclonal antibody capable of binding to biotin. In one embodiment the monoclonal antibody according to the invention also does not bind to a biotin moiety on a biotinylated molecule, wherein the biotin moiety is attached to the molecule via the carbon atom of the carboxyl function of the valeric acid moiety of biotin. Also disclosed is a method for generation of an antibody as disclosed herein. The monoclonal antibody according to the invention is of specific use in a method for measuring an analyte in a sample, wherein a (strept)avidin/biotin pair is used to bind a biotinylated analyte specific binding agent to a (strept)avidin coated solid phase.
-
-
-
-
-
-
-
-
-
搜索结果
27 条记录 (耗时 0.023 秒)
