公开(公告)号：US20220357303A1

公开(公告)日：2022-11-10

申请号：US17771366

申请日：2019-10-29

申请人： Agilent Technologies, Inc.

发明人： Kaike Zhu ,  Chenxi Chen ,  Wei-Jun Yao

IPC分类号： G01N30/40 ,  G01N30/20

摘要： A gas analyzer system (100, 200, 300) and methods of reducing sample carryover in a gas sample selector (102, 202, 302). The gas analyzer system (100, 200, 300) includes a gas chromatograph (104, 204, 304) and a gas sample selector (102, 202, 302). The gas sample selector (102, 202, 302) includes a multi-position selector valve (130, 230, 330), a flush valve (140, 240, 340), and a purge valve (150, 250, 350), as well as conduits providing flowpaths between them. When switching the flush valve (140, 240, 340) to connect the flush valve (140, 240, 340) vent and flush valve (140, 240, 340) outlet and flowing purge gas through the purge valve (150, 250, 350) port, the purge gas will flow to the selector (102, 202, 302) exit and to the flush valve (140, 240, 340) vent to remove sample gas from the flowpaths.

公开(公告)号：US20220018816A1

公开(公告)日：2022-01-20

申请号：US16933663

申请日：2020-07-20

申请人： Baker Hughes Oilfield Operations LLC

发明人： Salar Azizi ,  Nicklas Ritzmann

IPC分类号： G01N30/40 ,  E21B49/08 ,  G01N30/06

摘要： One or more embodiments of the present disclosure include a gas-analysis system. The gas-analysis system may include a first valve, a gas-measurement device, and a second valve. The first valve may be between a sample-gas line and a sample-gas outlet. The first valve may be configured to either allow or prevent gas movement between the sample-gas line and the sample-gas outlet. The gas-measurement device operatively coupled to a testing-gas line. The second valve may be between the sample-gas line, a flushing-gas inlet, and the testing-gas line. The second valve may be configured to allow gas movement from one of the sample-gas line or the flushing-gas inlet to the testing-gas line.

公开(公告)号：US11215590B2

公开(公告)日：2022-01-04

申请号：US16115732

申请日：2018-08-29

申请人： MLS ACQ, Inc.

发明人： Kelly Renee McPartland ,  Martin L. Spartz

IPC分类号： G01N30/20 ,  G01N30/12 ,  G01N30/74 ,  G01N30/30 ,  G01J3/42 ,  G01N30/40 ,  G01N30/32 ,  G01N30/72 ,  G01N21/3504 ,  G01N30/16 ,  G01N21/35 ,  G01N30/00 ,  G01N30/02

摘要： A method and system for sample analysis involve a temporally-resolving separation of sample components. In the method, solvent vapors are condensed prior to entering a temporally-resolving separator, a GC column, for example, and solvent-depleted vapors are directed to the separator where constituents are resolved in time. A system for analyzing a sample comprises an injection port, a temporally-resolving separator (e.g., a GC column) and a conduit connecting the two. The injection port is at a temperature sufficiently high to vaporize the solvent and analytes present in a sample. The conduit is configured and/or operated to condense the solvent, while maintaining the analytes in the vapor phase.

公开(公告)号：US20190277814A1

公开(公告)日：2019-09-12

申请号：US16335166

申请日：2016-10-11

申请人： Shimadzu Corporation

发明人： Yasuhiro KIMOTO ,  Shingo MASUDA

IPC分类号： G01N30/40 ,  G01N30/86

摘要： In a gas chromatograph 1, a back-pressure calculation processor 242 calculates a back pressure for a first detector. The pressure calculation processor 243 calculates a pressure of a carrier gas in a branching part. The back-flow determination processor 244 compares the pressure of the carrier gas in the branching part calculated by the pressure calculation processor 243 with the back pressure of the first detector calculated by the back-pressure calculation processor 242, and if the pressure of the carrier gas in the branching part is smaller than the back pressure of the first detector, the back-flow determination processor 244 determines that the carrier gas will flow back. It is therefore possible to surely know that there is a possibility that a back-flow of the carrier gas will occur, by checking the determination result of the back-flow determination processor 244.

公开(公告)号：US10036736B2

公开(公告)日：2018-07-31

申请号：US14714834

申请日：2015-05-18

申请人： IDEX Health & Science LLC

发明人： Jon Nichols ,  Michael Keller ,  Audrey Schrock ,  Carl Sims ,  Carl Servin

IPC分类号： G01N30/20 ,  F16K11/074 ,  G01N35/10 ,  G01N1/20 ,  F16K11/085 ,  G01N30/40 ,  G01N30/46 ,  G01N1/14 ,  G01N30/02 ,  G01N30/72

CPC分类号： G01N30/20 ,  F16K11/0743 ,  F16K11/0853 ,  G01N1/14 ,  G01N1/2035 ,  G01N30/40 ,  G01N30/463 ,  G01N30/7233 ,  G01N30/7286 ,  G01N35/1097 ,  G01N2001/205 ,  G01N2030/027 ,  G01N2030/202

摘要： A liquid sampling system includes a liquid sampling valve for transferring a liquid sample from a primary stream to a secondary stream. The liquid sampling valve includes a rotor having a movable shuttle that is in selective fluid communication with the primary stream or the secondary stream. The rotor shuttle passes through a discharge station prior to completion of the valve cycle to discharge contaminants prior to re-exposure to the primary stream.

公开(公告)号：US20180003681A1

公开(公告)日：2018-01-04

申请号：US15537144

申请日：2015-12-02

申请人： Siemens Aktiengesellschaft

发明人： Josef RICHTER ,  Piotr STRAUCH

IPC分类号： G01N30/20 ,  F16K11/02 ,  G01N30/46 ,  G01N30/40 ,  G01N30/02

CPC分类号： G01N30/20 ,  F16K11/022 ,  G01N30/40 ,  G01N30/468 ,  G01N2030/025 ,  G01N2030/201 ,  G01N2030/205 ,  G01N2030/402

摘要： A gas chromatograph that includes a metering chamber, two separating devices and a multiport valve unit having switching functions for metering, straight separation, cutting and backflush, where the multiport valve unit is formed as a multiport diaphragm valve.

公开(公告)号：US08361806B2

公开(公告)日：2013-01-29

申请号：US12986102

申请日：2011-01-06

申请人： Douglas T. Gjerde ,  Christopher T. Hanna

发明人： Douglas T. Gjerde ,  Christopher T. Hanna

IPC分类号： G01N1/18 ,  G01N30/96 ,  G01N30/04 ,  G01N30/14 ,  G01N30/40 ,  G01N30/84 ,  G01N33/68

CPC分类号： G01N1/34 ,  G01N1/40 ,  G01N1/405 ,  G01N30/00 ,  G01N30/06 ,  G01N30/08 ,  G01N2030/009 ,  G01N2030/062 ,  Y10T436/25 ,  Y10T436/25375 ,  Y10T436/255

摘要： The invention provides, inter alia, methods, devices and reagents for the preparation of native and non-denatured biomolecules using solid-phase extraction channels. The invention is particularly suited for the purification, concentration and/or analysis of protein analytes. The invention further provides, inter alia, methods, devices and reagents for the purification, concentration and/or analysis of multi-protein complexes.

摘要翻译： 本发明尤其提供了使用固相萃取通道制备天然和非变性生物分子的方法，装置和试剂。 本发明特别适用于蛋白质分析物的纯化，浓缩和/或分析。 本发明尤其还提供用于多蛋白复合物的纯化，浓缩和/或分析的方法，装置和试剂。

公开(公告)号：US06968729B1

公开(公告)日：2005-11-29

申请号：US10789663

申请日：2004-02-27

申请人： Arne Karlsson ,  Duncan E. Akporiaye ,  Svend A. Taftø ,  Ivar M. Dahl ,  Elisabeth M. Myhrvold ,  Arne L. Kvernheim

发明人： Arne Karlsson ,  Duncan E. Akporiaye ,  Svend A. Taftø ,  Ivar M. Dahl ,  Elisabeth M. Myhrvold ,  Arne L. Kvernheim

IPC分类号： G01N30/02 ,  G01N30/04 ,  G01N30/40

CPC分类号： G01N30/40 ,  G01N2030/025

摘要： The present invention comprises a method for expediting the analysis of a plurality of samples, preferably using gas chromatography. A specific embodiment comprises a dual isothermal heated zone configuration for use in combinatorial chemistry. This involves partitioning the samples into two isothermal zones, allowing detailed analysis of light components in a lower-temperature zone while heavy components are handled in a higher-temperature zone.

摘要翻译： 本发明包括用于加速多个样品的分析的方法，优选使用气相色谱法。 具体实施方案包括用于组合化学的双等温加热区构型。 这包括将样品分成两个等温区，允许在较低温度区域对轻组分进行详细分析，同时在较高温度区域处理重组分。

公开(公告)号：US6036921A

公开(公告)日：2000-03-14

申请号：US6096

申请日：1998-01-13

申请人： Hamish Small ,  Nebojsa Avdalovic ,  Yan Liu

发明人： Hamish Small ,  Nebojsa Avdalovic ,  Yan Liu

IPC分类号： G01N30/02 ,  B01J39/26 ,  B01J47/08 ,  G01N30/26 ,  G01N30/34 ,  G01N30/40 ,  G01N30/60 ,  G01N30/96

CPC分类号： B01J39/26 ,  B01J47/08 ,  G01N30/34 ,  G01N2030/407 ,  G01N2030/965 ,  G01N30/02 ,  Y10T436/117497

摘要： An apparatus for generating high purity acid or base in an aqueous stream for use as an eluent for chromatography and, particularly, ion chromatography. For generating a base for anion chromatography, the aqueous stream is directed through a cation exchange bed. An electrical potential is applied to the bed. Cations on the bed electromigrate into the aqueous stream while hydroxide ions are electrolytically generated to form a base-containing eluent. Anions to be detected and the generated eluent flow through a chromatographic separator and a detector. In one embodiment, between separation and detection, the separated anion stream flows through a second cation exchange bed with no electrical potential applied. The second bed serves as a suppressor. After completion of the desired number of cycles, flow through the first and second cation exchange beds may be reversed by appropriate valving for the next sample stream. An electrical potential is applied to the second bed while the potential is discontinued in the first bed. Thus, the second bed generates eluent and the first bed suppresses conductivity of the base. In another embodiment, the second cation exchange bed is disposed after the detector as a sink to retain the cations of the base and the eluent. By appropriate valving, flow may be reversed through the first and second beds with potential applied in the second bed but not the first bed. During the reversal setting of the valving, the second bed generates the base.

摘要翻译： 一种用于在水流中产生高纯度酸或碱的装置，用作色谱法的洗脱剂，特别是离子色谱法。 为了产生阴离子色谱法的碱，将水流引导通过阳离子交换床。 电位施加到床上。 床上的阳离子电迁移到水流中，同时电解产生氢氧根离子以形成含碱的洗脱液。 要检测的阴离子和产生的洗脱液流过色谱分离器和检测器。 在一个实施方案中，在分离和检测之间，分离的阴离子物流流过不施加电势的第二阳离子交换床。 第二张床是抑制者。 在完成所需数量的循环后，通过第一和第二阳离子交换床的流动可以通过用于下一个样品流的合适的阀来反转。 当第一床中的电位停止时，电位施加到第二床。 因此，第二床产生洗脱液，第一床抑制碱的导电性。 在另一个实施方案中，第二阳离子交换床设置在检测器之后作为水槽以保留碱和阳离子的阳离子。 通过适当的阀门，流动可以通过第一床和第二床反转，其中潜在地施加在第二床中而不是第一床。 在阀的反转设置期间，第二床产生基座。

公开(公告)号：US5726010A

公开(公告)日：1998-03-10

申请号：US738321

申请日：1991-07-31

申请人： Scott M. Clark

发明人： Scott M. Clark

IPC分类号： G01N33/538 ,  B01L3/00 ,  G01N30/02 ,  G01N30/40 ,  G01N30/90 ,  G01N33/543 ,  G01N33/558 ,  G01N37/00 ,  G01N33/569

CPC分类号： G01N33/558 ,  B01L3/5023 ,  B01L3/5055 ,  B01L2300/0663 ,  B01L2300/0672 ,  B01L2400/0677 ,  B01L2400/0683 ,  G01N30/02 ,  G01N30/40 ,  G01N30/90 ,  Y10S435/805 ,  Y10S435/81 ,  Y10S435/97 ,  Y10S435/974 ,  Y10S435/975 ,  Y10S436/805 ,  Y10S436/807 ,  Y10S436/809 ,  Y10S436/81

摘要： Disclosed are devices and methods for performing an assay which determines the presence or quantity of an analyte in a fluid sample by detecting binding of the analyte to at least one immobilized analyte capture reagent and washing unbound material from the immobilized analyte capture reagent. The devices and methods an elongated solid phase flow matrix, including capillary channels capable of driving capillary fluid movement, and further including (i) a first region adapted for receipt of the fluid sample, (ii) a second region at which the analyte capture reagent is immobilized, (iii) a third region for application of a wash reagent capable of removing unbound substances from the second region; and (iv) an absorbent reservoir of high volume capacity. The second region is positioned intermediate to the first region and the third region and intermediate to the absorbent reservoir and the third region. The device also includes means to detect analyte bound at the second region. The flow matrix and the regions thereof are sized and positioned to cause the fluid sample to flow initially along the elongated flow matrix in one direction toward and through the second region, and subsequently, the liquid reagent to flow along the elongated flow matrix in a second direction opposite the first direction, through the second region, and into the absorbent reservoir, drawing unbound substances with it.