公开(公告)号：US20240318283A1

公开(公告)日：2024-09-26

申请号：US18269411

申请日：2021-12-21

申请人： KOREA ATOMIC ENERGY RESEARCH INSTITUTE

发明人： Kang Hyuk CHOI ,  Ul Jae PARK ,  Jun Sing LEE ,  A Ran KIM

IPC分类号： C22B59/00 ,  B01D15/18 ,  B01D15/36 ,  B01D15/42 ,  C22B3/24 ,  C22B3/42 ,  G21G1/00

CPC分类号： C22B59/00 ,  B01D15/1871 ,  B01D15/362 ,  B01D15/426 ,  C22B3/24 ,  C22B3/42 ,  G21G1/001 ,  G21G2001/0094

摘要： The present invention relates to a method of producing and refining carrier-free lutetium-177 using chromatography, and more specifically to a method of producing and refining carrier-free lutetium 1-77 using chromatography having excellent resolution of lutetium and ytterbium without a concentration gradient of an eluent.

公开(公告)号：US20240295533A1

公开(公告)日：2024-09-05

申请号：US18592087

申请日：2024-02-29

申请人： Tata Consultancy Services Limited

发明人： VENKATA SUDHEENDRA BUDDHIRAJU ,  VENKATARAMANA RUNKANA ,  KARUNDEV PREMRAJ ,  SWATI SAHU ,  VISHNU SWAROOPJI MASAMPALLY

IPC分类号： G01N30/86 ,  B01D15/36 ,  B01D15/38 ,  G01N30/02

CPC分类号： G01N30/8658 ,  B01D15/362 ,  B01D15/3809 ,  G01N30/8693 ,  G01N2030/027

摘要： There has been a surge in usage of biotherapeutic products in multiple industries. The biotherapeutic products are a mixture of their charge variants which are separated by a continuous chromatography process. This disclosure provides a method and an apparatus for control and optimization of the continuous chromatography process. The present disclosure helps controlling composition of charge variants in biotherapeutic products by developing an apparatus that has unique architecture including advanced Distributed Control System (DCS), programmable logic controllers (PLCs), Local area network (LAN) setup and Python layer with user interface. This allows an operator to monitor charge variant concentrations and obtain an optimal schedule to implement such that a target product composition is achieved. The present disclosure comprises a data-pre-processing step followed by prediction of process parameters using soft sensor and prediction models. The chromatography process is optimized to achieve targeted purity and yield by recommending optimal values of manipulated variables.

公开(公告)号：US20240294685A1

公开(公告)日：2024-09-05

申请号：US18568609

申请日：2022-06-09

申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

发明人： Xiao SU ,  Haley VAPNIK ,  Johannes ELBERT

IPC分类号： C08F230/04 ,  B01D15/20 ,  B01D15/36 ,  C02F1/42 ,  C02F101/20 ,  C09D143/00

CPC分类号： C08F230/04 ,  B01D15/203 ,  B01D15/362 ,  C02F1/42 ,  C09D143/00 ,  C02F2001/425 ,  C02F2101/20 ,  C02F2303/16

摘要： Rare earth elements (REEs) play an essential role in our modern society, being critical resources for the growing electronic devices and renewable energy technologies. For the reversible capture and release of REEs, we designed and synthesized a redox-copolymer poly(ferrocenylpropyl methacrylamide-co-methacrylic acid) (P(FPMAm-co-MAA)) that combines an ion-exchange carboxylic acid group for REE adsorption, and an redox-active ferrocene moiety for electrochemical regeneration. By molecularly tuning the copolymer composition, efficient adsorption uptake could be achieved alongside electrochemically regenerated adsorbent reuse. The copolymer sorbent showed stoichiometric binding for yttrium (Y), cerium (Ce), neodymium (Nd), europium (Eu), gadolinium (Gd), and dysprosium (Dy) based on carboxylic acid active site.

公开(公告)号：US20240290513A1

公开(公告)日：2024-08-29

申请号：US18115599

申请日：2023-02-28

申请人： SHINE Technologies, LLC

发明人： Mark Johnson ,  Abdul Momen ,  Marek Piechowicz ,  Riley McSweeny

IPC分类号： G21F9/12 ,  B01D15/18 ,  B01D15/20 ,  B01D15/36

CPC分类号： G21F9/12 ,  B01D15/1871 ,  B01D15/203 ,  B01D15/362 ,  B01D15/363

摘要： A method of radionuclide waste extraction includes directing a waste stream from an upstream segment of a main waste pathway into a waste stream input of an anion exchange column, wherein the waste stream comprises uranium and a target radionuclide, the anion exchange column houses an anion exchange resin, a cation exchange column housing a cation exchange resin is fluidly coupled to the anion exchange column downstream the anion exchange column, and a sluicing preparation tank is fluidly coupled to the anion exchange column. The method further includes adsorbing uranium from the waste stream onto an anion exchange resin, directing the waste stream from the anion exchange column into the cation exchange column, adsorbing the radionuclide onto the cation exchange resin, removing spent anion exchange resin from the anion exchange column, and directing fresh anion exchange resin from the sluicing preparation tank into the anion exchange column.

公开(公告)号：US12036528B2

公开(公告)日：2024-07-16

申请号：US17403335

申请日：2021-08-16

申请人： UOP LLC

发明人： Gregory J. Lewis ,  Paulina Jakubczak ,  James M. Hodges ,  Evgeny Kolev ,  William Sheets ,  Mimoza Sylejmani-Rekaliu

IPC分类号： B01J20/16 ,  A61M1/36 ,  B01D15/36 ,  B01J20/28

CPC分类号： B01J20/16 ,  A61M1/3679 ,  B01D15/362 ,  B01J20/28026 ,  B01D2257/60

摘要： A process for removing Pb2+ toxins from bodily fluids involves contacting the bodily fluid with an ion exchange composition to remove the metal toxins in the bodily fluid, including blood and gastrointestinal fluid. Alternatively, blood can be contacted with a dialysis solution which is then contacted with the ion exchange composition. The ion exchange compositions are represented by the following empirical formula:

AmTiaNb1-aSixOy

having either the pharmacosiderite, sitinakite, pharmacosiderite-sitinakite intergrowth topologies or mixtures thereof. There are also compositions comprising the above ion exchange compositions in combination with bodily fluids or dialysis solution. The ion exchange compositions may be supported by porous networks of biocompatible polymers such as carbohydrates or proteins.

公开(公告)号：US11957997B1

公开(公告)日：2024-04-16

申请号：US17582821

申请日：2022-01-24

申请人： Yury Zelechonok

发明人： Yury Zelechonok

IPC分类号： B01D15/36 ,  B01D15/16

CPC分类号： B01D15/166 ,  B01D15/362 ,  B01D15/363

摘要： The present invention pertains to a liquid chromatography method of separating multicharged ions, and more particularly, to separating both positively charged and negatively charged ions by using a mobile phase composition with doubly charged ions and an ion-exchange column with a charged stationary phase surface.

公开(公告)号：US20240115974A1

公开(公告)日：2024-04-11

申请号：US17946006

申请日：2022-09-15

申请人： XEROX CORPORATION

发明人： Valerie M. Farrugia ,  Shivanthi Easwari Sriskandha ,  Matthew A. Heuft

IPC分类号： B01D15/36 ,  B01D69/10 ,  B01J47/12

CPC分类号： B01D15/362 ,  B01D15/361 ,  B01D69/10 ,  B01J47/12

摘要： A structured organic film (SOF) is disclosed. The structured organic film also includes a plurality of segments, a plurality of linkers, and optionally a plurality of capping segments, where at least one or more capping segments may include at least one cationic species. Implementations of the structured organic film (SOF) include where all of the plurality of linkers are bonded to the plurality of segments. A concentration of ionic capping segments in the SOF is from about 0.1 to about 5.0 molar equivalents of ionic capping segments as compared to a concentration of nonionic segments in the SOF. An ion-exchange membrane may include the structured organic film (SOF).

公开(公告)号：US11931719B2

公开(公告)日：2024-03-19

申请号：US16959373

申请日：2019-01-07

申请人： Puridify Ltd.

发明人： Marc Hummersone ,  Benjamin Wallis ,  Frederic Leroux ,  William Howard Albert Law

IPC分类号： B01D15/32 ,  B01D15/36 ,  B01J20/26 ,  B01J20/285 ,  B01J20/32 ,  B01J39/05 ,  B01J39/07 ,  B01J41/05 ,  B01J41/07

CPC分类号： B01J20/265 ,  B01D15/327 ,  B01D15/362 ,  B01D15/363 ,  B01J20/285 ,  B01J20/3274 ,  B01J39/05 ,  B01J39/07 ,  B01J41/05 ,  B01J41/07 ,  B01J2219/00844 ,  B01J2219/00846

摘要： The invention discloses a functionalised chromatography medium, comprising: i) at least one non-woven layer (10) of polymeric nano fibres (20) comprising a plurality of nanofibre-nano fibre fusion points (30); ii) a grafted polymer coating covering the polymeric nanofibres and the nanofibre-nanofibre fusion points; iii) a plurality of ligand groups covalently bound to the grafted polymer coating, wherein the ligand groups are capable of interacting with a target biomolecule.

公开(公告)号：US20240035117A1

公开(公告)日：2024-02-01

申请号：US17877925

申请日：2022-07-30

申请人： Pavel Kudryavtsev ,  Nikolai Kudriavtsev

发明人： Pavel Kudryavtsev ,  Nikolai Kudriavtsev

IPC分类号： C22B26/12 ,  B01D15/36 ,  B01D15/18 ,  B01D15/20 ,  C22B7/00 ,  C22B3/42 ,  B01J47/02 ,  B01J49/06 ,  B01J49/53 ,  B01J49/60 ,  B01J47/14

CPC分类号： C22B26/12 ,  B01D15/362 ,  B01D15/1871 ,  B01D15/1885 ,  B01D15/203 ,  C22B7/006 ,  C22B3/42 ,  B01J47/02 ,  B01J49/06 ,  B01J49/53 ,  B01J49/60 ,  B01J47/14

摘要： Provided are an apparatus and a method for ion-exchange extraction of lithium from natural or technological brine by using a lithium-selective inorganic sorbent operating on a principle of an ion sieve. The apparatus contains a plurality of ion-exchange columns arranged and interconnected in sequence. Flows of the brine, flush water, acidic desorption solution, and outputs, of the processed products are controlled via switchable shut-off valves. The method can be carried out by operating the apparatus in a parallel or a serial mode of column operations. In the parallel mode, all columns work simultaneously in the same manner. In the serial mode of operation, the columns work individually with a shift of the sorption-flushing-desorption-flushing cycles sequentially and with a transfer of the processed brined sequentially from the first column to the last column and from the last column to the first one thus providing continuity of the lithium-extraction process.

公开(公告)号：US20240026495A1

公开(公告)日：2024-01-25

申请号：US18476195

申请日：2023-09-27

申请人： Lilac Solutions, Inc.

发明人： David Henry SNYDACKER ,  Nicolás Andrés GROSSO GIORDANO ,  Amos INDRANADA ,  Alysia LUKITO ,  Sean UTAN ,  Mustafa Juzer BOOTWALA ,  Daniel Keane LAPORTE ,  Andrew Bolt BARBER ,  Christina FLEMING ,  Garrett LAU

IPC分类号： C22B26/12 ,  B01D15/20 ,  B01D15/36 ,  C22B3/42

CPC分类号： C22B26/12 ,  B01D15/203 ,  B01D15/362 ,  C22B3/42

摘要： The present invention relates to the extraction of lithium from liquid resources such as natural and synthetic brines, leachate solutions from clays and minerals, and recycled products with the assistance of an alternate phase.