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公开(公告)号：US20240238176A1
公开(公告)日：2024-07-18
申请号：US18401930
申请日：2024-01-02
发明人： Younchul KIM , Changsik SONG , Hwi Hyun MOON
CPC分类号： A61K8/29 , A61K8/0275 , A61Q17/04 , B01J20/06 , B01J20/265 , B01J20/3204 , B01J20/3219 , B01J20/3274 , B01J20/3293 , A61K2800/614
摘要： Disclosed are an anti-pollution cosmetic material and a method for preparing the same, wherein the anti-pollution cosmetic material contains a material having ultraviolet-blocking properties or heavy metal adsorption capacity or an organic-inorganic hybrid material having both ultraviolet-blocking properties and heavy metal adsorption capacity, so that the use of the inventive titanium dioxide (TiO2) composite particles and heteroatomic polymer-attached polyamino acid polymer can provide not only an ultraviolet-blocking or anti-pollution cosmetic composition but also a cosmetic composition having both an ultraviolet-blocking effect and an anti-pollution effect, and such a material can mitigate the white cast and the harmfulness of a microparticle powder, which are problems of existing inorganic sunblocks, and can be utilized as an anti-pollution material for skin protection having heavy metal adsorption capacity.
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公开(公告)号：US20240157331A1
公开(公告)日：2024-05-16
申请号：US18300285
申请日：2023-04-13
发明人： Seong Jin KIM , CHAE YOUNG AHN , Myoung-Woon MOON , Sangyeob LEE
CPC分类号： B01J20/28045 , B01J20/28007 , B01J20/3236 , B01J20/3274 , B01J20/3295
摘要： Provided is an oil-sorbent including a hydrophilic structure. The hydrophilic structure includes a plurality of macro pores. The macro pores have an average diameter of at least about 2 mm. An oil-sorbent includes a hydrophilic structure including a plurality of macro pores. The hydrophilic structure has an open-porous structure and has a porosity of at least 70%.
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公开(公告)号：US11980693B2
公开(公告)日：2024-05-14
申请号：US17148740
申请日：2021-01-14
发明人： Eric S. Gardiner , Magnus Paledzki
IPC分类号： A61L15/22 , A61L15/28 , A61L15/42 , A61L15/60 , B01J20/24 , B01J20/26 , B01J20/28 , B01J20/30 , B01J20/32 , B29C39/10 , C08G18/10 , C08G18/62 , C08G18/73 , C08L1/26 , C08L75/04 , B29K75/00 , B29K105/04 , B29L31/00
CPC分类号： A61L15/225 , A61L15/28 , A61L15/425 , A61L15/60 , B01J20/24 , B01J20/267 , B01J20/28023 , B01J20/28045 , B01J20/3085 , B01J20/3212 , B01J20/3219 , B01J20/3274 , B01J20/3282 , B01J20/3295 , C08G18/10 , C08G18/6212 , C08G18/73 , C08L1/26 , C08L75/04 , A61L2400/08 , B29C39/10 , B29K2075/00 , B29K2105/04 , B29K2713/00 , B29K2995/0092 , B29L2031/753 , C08G18/10 , C08G18/302
摘要： Disclosed is a method for making a composite material, which is of particular use in wound treatment. The composite material has a hydrophilic polyurethane foam material with a first polyurethane polymer; a hydrophilic fiber material having a second polymer, wherein said second polymer is not a polyurethane polymer and wherein said fiber material is capable of absorbing and retaining a fluid. The first polymer is covalently bonded to the second polymer.
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公开(公告)号：US20240124519A1
公开(公告)日：2024-04-18
申请号：US18235015
申请日：2023-08-17
IPC分类号： C07K1/22 , B01D15/16 , B01D15/38 , B01J20/289 , B01J20/32 , B01J39/26 , C07K16/06 , C07K16/28 , G01N33/68
CPC分类号： C07K1/22 , B01D15/168 , B01D15/3809 , B01J20/289 , B01J20/3204 , B01J20/3206 , B01J20/3219 , B01J20/3274 , B01J39/26 , C07K16/065 , C07K16/2866 , G01N33/6854
摘要： Herein is reported the use of an immobilized non-covalent complex of a neonatal Fc receptor (FcRn) and beta-2-microglobulin (b2m) as affinity chromotography ligand in general and, for example, for the determination of the in vivo half-live of an antibody by determining the ratio of the retention times of the antibody and a reference antibody.
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公开(公告)号：US20240091671A1
公开(公告)日：2024-03-21
申请号：US18460843
申请日：2023-09-05
申请人： Repligen Corporation
发明人： Erik Fiedler , Ulrich Haupts
CPC分类号： B01D15/3809 , B01J20/3274 , C07K1/22 , C07K14/31
摘要： The present invention relates to Fc binding proteins comprising one or more domains with Cysteine in the C-terminal helical region. The invention further relates to affinity matrices comprising the Fc binding proteins of the invention. The invention also relates to a use of these Fc binding proteins or affinity matrices for affinity purification of immunoglobulins and to methods of affinity purification using the Fc binding proteins of the invention.
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公开(公告)号：US11931719B2
公开(公告)日：2024-03-19
申请号：US16959373
申请日：2019-01-07
申请人： Puridify Ltd.
IPC分类号： B01D15/32 , B01D15/36 , B01J20/26 , B01J20/285 , B01J20/32 , B01J39/05 , B01J39/07 , B01J41/05 , B01J41/07
CPC分类号： B01J20/265 , B01D15/327 , B01D15/362 , B01D15/363 , B01J20/285 , B01J20/3274 , B01J39/05 , B01J39/07 , B01J41/05 , B01J41/07 , B01J2219/00844 , B01J2219/00846
摘要： The invention discloses a functionalised chromatography medium, comprising: i) at least one non-woven layer (10) of polymeric nano fibres (20) comprising a plurality of nanofibre-nano fibre fusion points (30); ii) a grafted polymer coating covering the polymeric nanofibres and the nanofibre-nanofibre fusion points; iii) a plurality of ligand groups covalently bound to the grafted polymer coating, wherein the ligand groups are capable of interacting with a target biomolecule.
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公开(公告)号：US20230391850A1
公开(公告)日：2023-12-07
申请号：US18249525
申请日：2021-11-10
发明人： Mats Ander , Gustav Rodrigo , Tomas Björkman
CPC分类号： C07K16/065 , B01D15/3809 , B01J20/286 , B01J20/3212 , B01J20/3274 , B01J20/28038 , C07K14/31
摘要： The invention relates to an alkali-stable mutated Fc-binding Protein A domain, having at least 95% identity to SEQ ID NO: 8 or SEQ ED NO: 9.
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公开(公告)号：US20230381739A1
公开(公告)日：2023-11-30
申请号：US18030858
申请日：2021-10-08
发明人： Jarad A. MASON , Malia B. WENNY , Daniel P. ERDOSY , Joy CHO , Christopher DELRE
CPC分类号： B01J20/226 , B01J20/28007 , B01J20/186 , B01J20/3204 , B01J20/3217 , B01J20/3274
摘要： To increase the gas solubility of polar liquids, the invention leverages coordination chemistry, nanoscience, and porous materials design to create porous liquids, e.g., aqueous solutions, containing a high density of networks of dry pores—which will feature dramatically higher capacities for dissolved gases than conventional polar liquids.
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公开(公告)号：US11685764B2
公开(公告)日：2023-06-27
申请号：US17221438
申请日：2021-04-02
IPC分类号： A23J1/00 , C07K1/22 , B01D15/38 , B01J20/24 , B01J20/28 , B01J20/286 , B01J20/32 , C07K14/31 , C07K16/00 , C07K16/06 , C07K17/10
CPC分类号： C07K1/22 , B01D15/3809 , B01J20/24 , B01J20/286 , B01J20/28016 , B01J20/28078 , B01J20/3212 , B01J20/3274 , C07K14/31 , C07K16/00 , C07K16/065 , C07K17/10
摘要： The invention relates to a separation matrix comprising at least 11 mg/ml Fc-binding ligands covalently coupled to a porous support, wherein:
a) the ligands comprise multimers of alkali-stabilized Protein A domains, and
b) the porous support comprises cross-linked polymer particles having a volume-weighted median diameter (d50, v) of 56-70 micrometers and a dry solids weight of 55-80 mg/ml.-
公开(公告)号：US11680081B2
公开(公告)日：2023-06-20
申请号：US16955119
申请日：2018-12-13
发明人： Gustav Rodrigo , Mats Ander , Ronnie Palmgren , Tomas Bjorkman
IPC分类号： C07K1/22 , B01D15/38 , B01J20/24 , B01J20/28 , B01J20/288 , B01J20/30 , B01J20/32 , C07K16/00
CPC分类号： C07K1/22 , B01D15/3809 , B01J20/24 , B01J20/288 , B01J20/28016 , B01J20/3071 , B01J20/3212 , B01J20/3217 , B01J20/3274 , B01J20/3295 , C07K16/00 , B01J2220/54
摘要： Methods that include providing and reacting a solid support and an alkali-stable ligand derived from an immunoglobulin-binding bacterial protein to form a separation matrix having covalently coupled alkali-stable ligands; and washing with a wash solution comprising at least 10 mM of an alkali metal hydroxide.
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