公开(公告)号：US12121879B2

公开(公告)日：2024-10-22

申请号：US17298968

申请日：2019-12-02

申请人： CytoSorbents Corporation

发明人： Tamaz Guliashvili ,  Maryann Gruda ,  Thomas Golobish ,  David James ,  Karl-Gustav Ruggeberg ,  Pamela O'Sullivan ,  Sarah Patterson

IPC分类号： B01J20/32 ,  B01D15/38 ,  B01J20/28 ,  C07K1/22 ,  C07K16/06

CPC分类号： B01J20/3274 ,  B01D15/3809 ,  B01J20/28019 ,  B01J20/28078 ,  B01J20/3212 ,  C07K1/22 ,  C07K16/065

摘要： The invention concerns polymeric media based on modified natural polysaccharides for removing one or both of Anti-A Antibodies and Anti-B Antibodies from human blood or plasma, the media comprising one or both of (i) a polymeric solid support with a blood group A Antigen ligand attached to the solid support at a ligand loading between 1-5 mg/mL of solid support, and wherein the media is stable under physiological pH conditions, and (ii) a polymeric solid support with a blood group B Antigen ligand attached to the solid support at a ligand loading between 1-5 mg/mL of solid support, and wherein the media is stable under physiological pH conditions.

公开(公告)号：US12115467B2

公开(公告)日：2024-10-15

申请号：US17617059

申请日：2020-06-12

申请人： DAICEL CORPORATION

发明人： Toru Shibata ,  Satoshi Shinkura ,  Atsushi Ohnishi

IPC分类号： B01D15/36 ,  B01D15/16 ,  B01D15/32 ,  B01D15/38 ,  B01J20/28 ,  B01J20/286 ,  B01J20/29 ,  B01J20/32 ,  B01J41/20 ,  G01N30/02

CPC分类号： B01D15/36 ,  B01D15/166 ,  B01D15/32 ,  B01D15/38 ,  B01D15/3833 ,  B01J20/286 ,  B01J20/29 ,  B01J20/3204 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3219 ,  B01J20/3255 ,  B01J41/20 ,  G01N30/02 ,  G01N2030/027

摘要： Provided is a separation method for amine, the separation method including performing liquid chromatography, wherein a separating agent in which a ligand having a crown ether-like cyclic structure is supported on a carrier is used as a stationary phase, and wherein a mobile phase contains an aqueous solution of at least one salt of a hydrophobic anion selected from the group consisting of a salt of a chaotropic anion and a salt of a hydrophobic organic acid.

公开(公告)号：US20240139394A1

公开(公告)日：2024-05-02

申请号：US18407992

申请日：2024-01-09

申请人： KANEKA CORPORATION ,  BROAD BEAN SCIENCE CO., LTD.

发明人： Ai YONEZAWA ,  Kana WATANABE ,  Makoto KUROO

IPC分类号： A61M1/34 ,  A61M1/36 ,  B01D15/00 ,  B01J20/24 ,  B01J20/32 ,  C07K1/14

CPC分类号： A61M1/3496 ,  A61M1/3687 ,  B01D15/00 ,  B01J20/24 ,  B01J20/3212 ,  B01J20/3219 ,  B01J20/3265 ,  B01J20/3293 ,  C07K1/14

摘要： The purpose of the present invention is to adsorb calciprotein particles. An adsorbent for calciprotein particles of the present invention is characterized in that the surface of a water-insoluble carrier is covalently bonded, through a hydrocarbon group, to at least one selected from the group consisting of amino group, carboxyl group, phosphate group, phosphono group, phosphino group, and thiol group.

公开(公告)号：USRE49773E1

公开(公告)日：2024-01-02

申请号：US17323779

申请日：2021-05-18

申请人： NANOPAREIL, LLC

发明人： Todd J. Menkhaus ,  Hao Fong

IPC分类号： B01D39/16 ,  B01D15/32 ,  B01D15/36 ,  B01D15/38 ,  B01J20/24 ,  B01J20/28 ,  B01J20/32 ,  C07K1/22 ,  D01D5/00 ,  D01F2/24 ,  D01F6/44 ,  D01F6/88 ,  H01L23/48 ,  H01L23/00 ,  H01L25/065 ,  H01L25/00

CPC分类号： B01D39/1615 ,  B01D15/327 ,  B01D15/361 ,  B01D15/3809 ,  B01D39/1623 ,  B01D39/1676 ,  B01J20/24 ,  B01J20/28007 ,  B01J20/28038 ,  B01J20/3212 ,  B01J20/3217 ,  B01J20/3248 ,  B01J20/3293 ,  C07K1/22 ,  D01D5/003 ,  D01D5/0007 ,  D01F2/24 ,  D01F6/44 ,  D01F6/88 ,  H01L23/48 ,  H01L24/72 ,  H01L24/73 ,  H01L24/90 ,  H01L24/91 ,  H01L25/0652 ,  H01L25/50 ,  B01D15/3804 ,  B01D2239/025 ,  B01D2239/0414 ,  H01L24/16 ,  H01L2224/131 ,  H01L2224/16227 ,  H01L2224/73201 ,  H01L2224/81138 ,  H01L2224/81815 ,  H01L2224/9211 ,  H01L2225/06517 ,  H01L2225/06527 ,  H01L2225/06531 ,  H01L2225/06562 ,  H01L2225/06593 ,  H01L2924/0002 ,  H01L2924/157 ,  H01L2924/1579 ,  H01L2924/15153 ,  H01L2924/15787 ,  H01L2924/15788 ,  H01L2924/3511 ,  H01L2924/37001 ,  H01L2924/0002 ,  H01L2924/00 ,  H01L2924/15788 ,  H01L2924/00 ,  H01L2224/131 ,  H01L2924/014 ,  H01L2224/73201 ,  H01L2224/16 ,  H01L2224/72 ,  H01L2224/9211 ,  H01L2224/81 ,  H01L2224/90 ,  H01L2224/81815 ,  H01L2924/00014 ,  H01L2224/81138 ,  H01L2924/00012

摘要： The present invention relates generally to compositions for use in biological and chemical separations, as well as other applications. More specifically, the present invention relates to hybrid felts fabricated from electrospun nanofibers with high permeance and high capacity. Such hybrid felts utilize derivatized cellulose, and at least one non-cellulose-based polymer that may be removed from the felt by subjecting it to moderately elevated temperatures and/or solvents capable of dissolving the non-cellulose-based polymer to leave behind a porous nanofiber felt having more uniform pore sizes and other enhanced properties when compared to single component nanofiber felts.

公开(公告)号：US20230257417A1

公开(公告)日：2023-08-17

申请号：US18181974

申请日：2023-03-10

申请人： Cytiva BioProcess R&D AB

发明人： Annika Kristina Forss ,  Gustav Jose Rodrigo ,  Tomas Bjorkman ,  Jesper Ulf Hansson ,  Mats Ander

IPC分类号： C07K1/22 ,  C07K16/12 ,  C07K17/10 ,  B01J20/286 ,  C07K14/31 ,  C07K16/06 ,  B01D15/00 ,  B01J20/32

CPC分类号： C07K1/22 ,  C07K16/1271 ,  C07K17/10 ,  B01J20/286 ,  C07K14/31 ,  C07K16/065 ,  B01D15/00 ,  B01J20/3274 ,  B01J20/3212 ,  B01J2220/52

摘要： The invention relates to a method of isolating an immunoglobulin, comprising the steps of: a) providing a separation matrix comprising multimers of immunoglobulin-binding alkali-stabilized Protein A domains covalently coupled to a porous support: b) contacting a liquid sample comprising an immunoglobulin with the separation matrix; c) washing said separation matrix with a washing liquid; d) eluting the immunoglobulin from the separation matrix with an elution liquid, and e) cleaning the separation matrix with a cleaning liquid, wherein the alkali-stabilized Protein A domains comprise mutants of a parental Fc-binding domain of Staphylococcus Protein A (SpA).

公开(公告)号：US20230249991A1

公开(公告)日：2023-08-10

申请号：US18117247

申请日：2023-03-03

申请人： KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

发明人： Tawfik Abdo Saleh AWADH ,  Nadeem BAIG

IPC分类号： C02F1/28 ,  B01J20/26 ,  B01J20/20 ,  B01J20/28 ,  B01J20/32

CPC分类号： C02F1/288 ,  B01J20/261 ,  B01J20/20 ,  B01J20/28045 ,  B01J20/28085 ,  B01J20/28083 ,  B01J20/28059 ,  B01J20/3212 ,  B01J20/3225 ,  B01J20/324 ,  B01J20/327 ,  B01J20/262 ,  C02F2303/16 ,  C02F1/281 ,  C02F1/285 ,  C02F2101/32

摘要： A composite material of polyurethane foam having a layer of reduced graphene oxide and polystyrene is described. This composite material may be made by contacting a polyurethane foam with a suspension of reduced graphene oxide, drying, and then irradiating in the presence of styrene vapor. The composite material has a hydrophobic surface that may be exploited for separating a nonpolar phase, such as oil, from an aqueous solution.

公开(公告)号：US20190184371A1

公开(公告)日：2019-06-20

申请号：US16327188

申请日：2017-09-08

申请人： TORAY INDUSTRIES, INC.

发明人： Shungo KANDA ,  Hiroshi TAKAHASHI ,  Naotoshi TOMITA

IPC分类号： B01J20/26 ,  B01J20/28 ,  B01J20/32 ,  B01D15/38

CPC分类号： B01J20/265 ,  A61M1/36 ,  B01D15/3828 ,  B01J20/22 ,  B01J20/28 ,  B01J20/28016 ,  B01J20/28023 ,  B01J20/28038 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3219 ,  B01J20/3251 ,  B01J20/3293 ,  B01J20/3295

摘要： An object of the present invention is to provide a material for blood purification having the capability to remove cytokines and activated leukocyte-activated platelet complexes. The present invention provides a material for blood purification, the material containing a water-insoluble material in which a ligand having an amide group(s) and an amino group(s) is bound to a substrate, wherein the content of the amide group(s) is 3.0 to 7.0 mmol per 1 g dry weight of the water-insoluble material; and wherein the content of the amino group(s) is 1.0 to 7.0 mmol per 1 g dry weight of the water-insoluble material.

公开(公告)号：US20180228209A1

公开(公告)日：2018-08-16

申请号：US15751700

申请日：2016-07-25

申请人： Jinan Shengquan Group Share Holding Co., Ltd.

发明人： Yilin TANG ,  Jinzhu ZHANG ,  An ZHANG ,  Ding LIU

IPC分类号： A24D3/16 ,  A24D1/04 ,  B01D53/02 ,  B01J20/20 ,  B01J20/28 ,  B01J20/32 ,  B01J20/30 ,  F24F3/16 ,  F01N3/08

CPC分类号： A24D3/163 ,  A24D1/045 ,  A24D3/16 ,  B01D53/02 ,  B01D2253/102 ,  B01D2257/502 ,  B01D2257/7027 ,  B01J20/20 ,  B01J20/205 ,  B01J20/28023 ,  B01J20/28054 ,  B01J20/3071 ,  B01J20/3212 ,  B01J20/324 ,  B01J20/3293 ,  F01N3/0828 ,  F24F3/1603 ,  F24F2003/1646

摘要： A graphene adsorbing material, a preparation method therefor and application thereof, and a cigarette filter tip and a cigarette are provided. The graphene adsorbing material comprises a fiber carrier, graphene and doped elements wherein the graphene and the doped elements are loaded on the fiber carrier and the doped elements comprise at least one of Al, Si and Fe. The graphene adsorbing material is obtained by contacting the fibers with the graphene material to load the graphene material on the fibers. By introducing the graphene and the doped elements in the fiber carrier, harmful substances with a type of fused aromatic hydrocarbons such as benzopyrene in smoke can be specifically adsorbed, filtered and removed; while nicotine and the other harmless substances are retained, and thus the smoking taste of a cigarette is not affected. The cigarette filter tip can effectively adsorb cancerogenic substances with a type of fused aromatic hydrocarbons such as benzopyrene in smoke to reduce harm of smoking; meanwhile, the pleasure of smoking and the mellow taste of the smoke are not affected. Besides, the graphene adsorbing material can also prevent the phenomenon that a cigarette holder gets mildewed due to humid environment and the other factors.

公开(公告)号：US10035128B2

公开(公告)日：2018-07-31

申请号：US15786112

申请日：2017-10-17

申请人： Cellresin Technologies, LLC

发明人： Willard E. Wood

IPC分类号： B01J20/26 ,  B01D53/04 ,  B01J20/32 ,  B01J20/28 ,  B01J20/10 ,  B01D53/48 ,  B01D53/02 ,  B01D53/52

CPC分类号： B01J20/262 ,  B01D53/02 ,  B01D53/04 ,  B01D53/48 ,  B01D53/52 ,  B01D2253/106 ,  B01D2253/112 ,  B01D2253/202 ,  B01D2253/25 ,  B01D2253/306 ,  B01D2255/20738 ,  B01D2257/304 ,  B01D2257/306 ,  B01D2257/706 ,  B01D2257/90 ,  B01D2259/4541 ,  B01J20/103 ,  B01J20/28011 ,  B01J20/28023 ,  B01J20/28057 ,  B01J20/3204 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3236 ,  B01J20/3248 ,  Y10T428/1362 ,  Y10T442/2508

摘要： Compositions that can be used to adsorb low concentration, of unwanted or target substances from a dynamic fluid stream or from an enclosed static vapor phase. Such adsorbency can be obtained with thermoplastic materials used in the form of bulk polymer or a film, fiber, web, woven fabric, non-woven fabric, sheet, packaging and other such structures including or surrounding the enclosed volume. The concentration should be reduced to non-offensive sensed limits or a limit that does not produce a biological response.

公开(公告)号：US20180178192A1

公开(公告)日：2018-06-28

申请号：US15748542

申请日：2016-07-29

申请人： NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY ,  NAGASE CHEMTEX CORPORATION

发明人： Masayo SAKATA ,  Towako SAKAMOTO ,  Daisuke NAKAMURA ,  Yuki MAEDA

IPC分类号： B01J20/24 ,  B01J20/28 ,  B01D15/36 ,  C02F1/42

CPC分类号： B01J20/24 ,  A61K9/70 ,  A61K47/38 ,  B01D15/00 ,  B01D15/36 ,  B01D15/363 ,  B01J20/22 ,  B01J20/262 ,  B01J20/265 ,  B01J20/28004 ,  B01J20/28007 ,  B01J20/28023 ,  B01J20/30 ,  B01J20/3085 ,  B01J20/3212 ,  B01J20/3248 ,  C02F1/28 ,  C02F1/42 ,  C02F2001/422 ,  C02F2101/34

摘要： Means for removing endotoxin is provided. Endotoxin is removed by contacting an endotoxin adsorbent including a cellulose nanofiber having an amino group with a liquid containing endotoxin.