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1.发明申请公开(公告)号：US20180052099A1
公开(公告)日：2018-02-22
申请号：US15387180
申请日：2016-12-21
发明人： Andrew V. Hill , Amnon Manassen , Ohad Bachar
CPC分类号： G01N21/255 , G01J1/0418 , G01J1/4257 , G01J3/0208 , G01J3/021 , G01J3/06 , G01J3/10 , G01J3/12 , G01J2001/4247 , G01J2003/069 , G01J2003/1213 , G01J2003/1217 , G01J2003/1221 , G01J2003/1234 , G01N2201/0666 , G01N2201/0668 , G01N2201/0675 , G01N2201/0683 , G03F7/70633
摘要： A metrology system includes an illumination source to generate an illumination beam, a multi-channel spectral filter, a focusing element to direct illumination from the single optical column to a sample, and at least one detector to capture the illumination collected from the sample. The multi-channel spectral filter includes two or more filtering channels having two or more channel beam paths. The two or more filtering channels filter illumination propagating along the two or more channel beam paths based on two or more spectral transmissivity distributions. The multi-channel spectral filter further includes a channel selector to direct at least a portion of the illumination beam into at least one selected filtering channel to filter the illumination beam. The multi-channel spectral filter further includes at least one beam combiner to combine illumination from the two or more filtering channels to a single optical column.
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公开(公告)号：US09857302B2
公开(公告)日：2018-01-02
申请号：US15009608
申请日：2016-01-28
发明人： Yongkeun Park , Jung-Hoon Park , Yong-Hoon Cho , Chunghyun Park
CPC分类号： G01N21/4788 , G01N21/45 , G01N21/49 , G01N2021/479 , G01N2201/0675 , G01Q60/18 , G01Q60/22
摘要： An apparatus for manipulating surface near-field light resulting from light emitted from a light source that passes through a scattering layer is disclosed. Also, a method of finding a phase of incident light to cause constructive interference at a target spot using light scattering to manipulate the surface near-field.
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公开(公告)号：US20170343477A1
公开(公告)日：2017-11-30
申请号：US15607457
申请日：2017-05-27
发明人： Charles Santori , Supriyo Sinha , Cheng-Hsun Wu , James Higbie , Seung Ah Lee
CPC分类号： G01N21/6486 , A61B5/0071 , A61B5/0075 , G01J3/0224 , G01J3/0229 , G01J3/10 , G01J3/18 , G01J3/2823 , G01J3/32 , G01J3/433 , G01J3/4406 , G01J2003/1243 , G01N21/6408 , G01N21/6445 , G01N21/6458 , G01N2021/6471 , G01N2201/0675 , G02B21/004 , G02B21/0076 , G02B21/16
摘要： Systems and methods for hyperspectral imaging are described. In one implementation, a hyperspectral imaging system includes a sample holder configured to hold a sample, an illumination system, and a detection system. The illumination system includes a light source configured to emit excitation light having one or more wavelengths, and a first set of optical elements that include a first spatial light modulator (SLM), at least one lens, and at least one dispersive element. The illumination system is configured to structure the excitation light into a predetermined two-dimensional pattern at a conjugate plane of a focal plane in the sample, spectrally disperse the structured excitation light in a first lateral direction, and illuminate the sample in an excitation pattern with the one or more wavelengths dispersed in the first lateral direction.
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公开(公告)号：US09753296B2
公开(公告)日：2017-09-05
申请号：US14805402
申请日：2015-07-21
CPC分类号： G02B27/283 , G01J1/08 , G01N21/8806 , G01N21/9501 , G01N2021/8848 , G01N2201/0675 , G02F1/01 , G03F7/70633
摘要： In an illumination system (12, 13) for a scatterometer, first and second spatial light modulators lie in a common plane and are formed by different portions of a single liquid crystal cell (260). Pre-polarizers (250) apply polarization to first and second radiation prior to the spatial light modulators. A first spatial light modulator (236-S) varies a polarization state of the first radiation in accordance with a first programmable pattern. Second spatial light modulator (236-P) varies a polarization state of the second radiation accordance with a second programmable pattern. A polarizing beam splitter (234) selectively transmits each of the spatially modulated first and second radiation to a common output path, depending on the polarization state of the radiation. In an embodiment, functions of pre-polarizers are performed by the polarizing beam splitter.
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公开(公告)号：US20170082597A1
公开(公告)日：2017-03-23
申请号：US15312054
申请日：2015-05-20
发明人： Naoya MATSUMOTO , Koyo WATANABE , Hirotoshi TERADA
CPC分类号： G01N33/4833 , G01B11/24 , G01N21/41 , G01N21/636 , G01N21/6458 , G01N21/6486 , G01N2021/6471 , G01N2201/0675 , G02B5/32 , G02B21/00 , G02B27/0068 , G03H1/0005 , G03H1/08 , G03H1/2294
摘要： A photostimulation apparatus includes an objective lens arranged to face a biological object, a light source configured to output light to be radiated toward the biological object via the objective lens, a shape acquisition unit configured to acquire information about a shape with a refractive index difference in the biological object, a hologram generation unit configured to generate aberration correction hologram data for correcting aberrations due to the shape with the refractive index difference on the basis of the information acquired by the shape acquisition unit, and a spatial light modulator on which a hologram based on the aberration correction hologram data is presented and which modulates the light output from the light source.
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6.发明授权公开(公告)号：US09581797B2
公开(公告)日：2017-02-28
申请号：US15180301
申请日：2016-06-13
IPC分类号： G01J3/28 , G02B21/00 , G01J3/02 , G01N21/25 , G02B21/36 , G01J3/18 , G02F1/1335 , G02F1/29 , G02B5/18 , G02B26/08 , G01N21/27 , G02B21/06 , G02F1/23 , G06T7/00 , G06T7/40 , H04N5/225 , H04N5/33 , G01J3/50 , G01J3/12 , G01J3/46 , G02B6/293
CPC分类号： G02B21/0064 , G01J3/0205 , G01J3/021 , G01J3/0229 , G01J3/0237 , G01J3/18 , G01J3/502 , G01J2003/1278 , G01J2003/468 , G01N21/255 , G01N21/27 , G01N2201/06113 , G01N2201/0675 , G02B5/1828 , G02B6/2931 , G02B21/06 , G02B21/361 , G02B26/0808 , G02F1/133553 , G02F1/23 , G02F1/292 , G06T7/11 , G06T7/90 , G06T2207/10024 , G06T2207/10056 , G06T2207/10064 , G06T2207/30004 , H04N5/2256 , H04N5/332
摘要： An imaging system includes a light source configured to illuminate a target and a camera configured to image light responsively emitted from the target and reflected from a spatial light modulator (SLM). The imaging system is configured to generate high-resolution, hyperspectral images of the target. The SLM includes a refractive layer that is chromatically dispersive and that has a refractive index that is controllable. The refractive index of the refractive layer can be controlled to vary according to a gradient such that light reflected from the SLM is chromatically dispersed and spectrographic information about the target can be captured using the camera. Such a system could be operated confocally, e.g., by incorporating a micromirror device configured to control a spatial pattern of illumination of the target and to modulate the transmission of light from the target to the camera via the SLM according to a corresponding spatial pattern.
摘要翻译： 成像系统包括被配置为照射目标的光源和被配置为对从目标发射并从空间光调制器（SLM）反射的）反射的图像的照相机。 成像系统被配置为产生目标的高分辨率，高光谱图像。 SLM包括色度分散且具有可控制的折射率的折射层。 折射层的折射率可以根据梯度来变化，使得从SLM反射的光被色散，并且可以使用照相机捕获关于目标的光谱信息。 这样的系统可以协调地操作，例如通过结合配置成控制目标的照明的空间模式的微镜装置，并且根据对应的空间模式经由SLM调制从目标到照相机的光的传输。
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公开(公告)号：US20160274355A1
公开(公告)日：2016-09-22
申请号：US15166668
申请日：2016-05-27
发明人： Xiaodong Tao , Joel A. Kubby
CPC分类号： G02B27/0068 , G01J9/00 , G01N21/45 , G01N21/49 , G01N21/6428 , G01N21/6458 , G01N2021/4709 , G01N2021/6439 , G01N2201/06113 , G01N2201/0675 , G01N2201/121 , G02B21/16 , G02B21/244 , G02B21/245 , G02B21/361 , G02B21/365 , G02B27/0927
摘要： Interferometric focusing (IF), rather than conventional geometric focusing, of excitation light onto a guide-star that is embedded deeply in tissue, increases its fluorescence intensity. The method can extend the depth of wavefront measurement and improve correction inside of tissues because of its ability to suppress both scattering of diffuse light and aberration of ballistic light. The results showed more than two times improvement in SNR and RMS error of the wavefront measurement. Although only ballistic light in the excitation path is corrected, the intensity after wavefront correction increased by 1.5 times. When applying IF to a two-photon microscope with a near infra-red laser, this method would further extend the measurement depth and achieve high SNR for the wavefront sensor.
摘要翻译： 干涉测深（IF），而不是传统的几何聚焦，激发光到深埋在组织中的引导星，增加其荧光强度。 该方法可以延长波前测量的深度，并改善组织内部的校正，因为其能够抑制漫射光的散射和弹道光的差异。 结果显示波前测量的SNR和RMS误差提高了两倍以上。 虽然激励路径中只有弹道光被校正，波前校正后的强度增加了1.5倍。 当将IF应用于具有近红外激光器的双光子显微镜时，该方法将进一步扩展测量深度并实现波前传感器的高SNR。
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8.发明申请ADAPTIVE OPTICS FOR IMAGING THROUGH HIGHLY SCATTERING MEDIA IN OIL RESERVOIR APPLICATIONS 有权通过油藏储存应用中高分辨率介质成像的自适应光学公开(公告)号：US20160259156A1
公开(公告)日：2016-09-08
申请号：US15061056
申请日：2016-03-04
发明人： Thomas Bifano , Shannon L. Eichmann , Bennett B. Goldberg , Mazen Kanj , Hari P. Paudel , William Shain
CPC分类号： G02B21/0028 , G01N21/6458 , G01N2201/0675 , G02B21/002 , G02B21/0032 , G02B21/0048 , G02B21/0076 , G02B21/008 , G02B21/02 , G02B21/367 , G02B27/0068
摘要： Embodiments of the invention provide an imaging system and method using adaptive optics and optimization algorithms for imaging through highly scattering media in oil reservoir applications and lab-based petroleum research. Two-/multi-photon fluorescence microscopy is used in conjunction with adaptive optics for enhanced imaging and detection capabilities in scattering reservoir media. Advanced fluorescence techniques are used to allow for super-penetration imaging to compensate for aberrations both in and out of the field of interest, extending the depth at which pore geometry can be imaged within a rock matrix beyond the current capability of confocal microscopy. The placement of a Deformable Mirror or Spatial Light Modulator for this application, in which scattering and index mismatch are dominant aberrations, is in an optical plane that is conjugate to the pupil plane of the objective lens in the imaging system. The invention images stationary and dynamic nanoparticles, surfactants, fluid-fluid interfaces and tracers which can be used to study properties such as diffusion, mobility, adhesion, stickiness and wettability within the 3D structure of cores and thin sections.
摘要翻译： 本发明的实施例提供了一种使用自适应光学和优化算法的成像系统和方法，用于通过油藏应用中的高散射介质和基于实验室的石油研究进行成像。 双光子/多光子荧光显微镜与自适应光学结合使用，用于在散射储层介质中增强成像和检测能力。 先进的荧光技术被用于允许超级穿透成像补偿在感兴趣的领域内外的像差，从而扩展了在几何形状可以在岩石基质内成像超过目前的共聚焦显微镜能力的深度。 在该应用中，散射和折射率失配是主要像差的可变形镜或空间光调制器的放置在与成像系统中的物镜的光瞳平面共轭的光学平面中。 本发明将稳定和动态的纳米颗粒，表面活性剂，流体 - 流体界面和示踪剂图像化，可用于研究核心和薄部分的3D结构内的扩散，迁移率，粘附性，粘性和润湿性等性质。
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公开(公告)号：US20160146731A1
公开(公告)日：2016-05-26
申请号：US15009608
申请日：2016-01-28
发明人： Yongkeun Park , Jung-Hoon Park , Yong-Hoon Cho , Chunghyun Park
CPC分类号： G01N21/4788 , G01N21/45 , G01N21/49 , G01N2021/479 , G01N2201/0675 , G01Q60/18 , G01Q60/22
摘要： An apparatus for manipulating surface near-field light resulting from light emitted from a light source that passes through a scattering layer is disclosed. Also, a method of finding a phase of incident light to cause constructive interference at a target spot using light scattering to manipulate the surface near-field.
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10.发明授权公开(公告)号：US09279764B2
公开(公告)日：2016-03-08
申请号：US14137967
申请日：2013-12-20
发明人： Yongkeun Park , Jung-Hoon Park , Yong-Hoon Cho , Chunghyun Park
CPC分类号： G01N21/4788 , G01N21/45 , G01N21/49 , G01N2021/479 , G01N2201/0675 , G01Q60/18 , G01Q60/22
摘要： An apparatus for manipulating surface near-field light resulting from light emitted from a light source that passes through a scattering layer is disclosed. Also, a method of finding a phase of incident light to cause constructive interference at a target spot using light scattering to manipulate the surface near-field.
摘要翻译： 公开了一种用于操纵从通过散射层的光源发射的光产生的表面近场光的装置。 此外，发现入射光的相位以使用光散射在目标点造成建设性干扰以操纵表面近场的方法。
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