公开(公告)号：US20240110868A1

公开(公告)日：2024-04-04

申请号：US18012374

申请日：2022-09-01

申请人： THE WAVE TALK, INC.

发明人： Young Dug KIM ,  Kyoung Man CHO ,  Doo Young CHEON

IPC分类号： G01N21/47 ,  G01N21/51 ,  G01N33/18

CPC分类号： G01N21/4788 ,  G01N21/51 ,  G01N33/1826 ,  G01N2021/479

摘要： A water examination device includes a main body; a fluid accommodation unit formed in the main body; a wave source for irradiating waves toward the fluid accommodation unit; a detector for detecting a laser speckle in time series, the laser speckle being generated due to multiple scattering of the waves in the fluid; and a controller for estimating existence of foreign material in the fluid in real-time by using the detected laser speckle. An imaginary first plane passing through the wave source is parallel to an imaginary second plane passing through the detector.

公开(公告)号：US20190212276A1

公开(公告)日：2019-07-11

申请号：US16305982

申请日：2017-06-01

申请人： THE WAVE TALK, INC. ,  KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

发明人： Young Dug KIM ,  Jongchan PARK ,  YongKeun PARK

IPC分类号： G01N21/95 ,  G01N21/47

CPC分类号： G01N21/9501 ,  G01N21/4788 ,  G01N21/9505 ,  G01N21/95607 ,  G01N21/95684 ,  G01N2021/479 ,  G01N2021/95615 ,  G01N2201/0668 ,  G02B26/12 ,  G02B27/48

摘要： According to an aspect of the present invention, there is provided a pattern structure inspection method including irradiating a wave from a wave source onto a sample including a pattern region in which a structure having a certain pattern is provided on a substrate, collecting speckle data generated due to multiple scattering of the wave in the pattern region, by using a data collector, and analyzing whether the structure of the pattern region has a defect, by comparing the collected speckle data to reference speckle data.

公开(公告)号：US20180321219A1

公开(公告)日：2018-11-08

申请号：US15770356

申请日：2015-10-26

申请人： Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e. V.

发明人： Heiko ZIMMERMANN ,  Frank STRACKE ,  Ronan LE HARZIC

IPC分类号： G01N33/50 ,  G01N21/21 ,  G01N21/47 ,  G01N21/49

CPC分类号： G01N21/4788 ,  G01N21/21 ,  G01N21/49 ,  G01N2021/479 ,  G01P13/00

摘要： The invention relates to a method and a device for the optical in vitro detection of a movement in a biological sample and/or for the optical in vitro detection of a movement of a component of the biological sample. The method has the following step: (a) providing an optical wide-field illumination device for illuminating the sample, said device being designed to illuminate the entire sample, and a detector (3) for detecting radiation (9; 9a, 9b) coming from the sample. The detector (3) has a detection surface (3a) which is divided into multiple detection regions (4a). The detector is additionally designed to derive (S1) detection signals (4c) of individual detection regions (4a) with respect to time, subsequently rectify (S2) the signals, preferably by generating an absolute value or squaring, and summing or averaging (S3) the derived and rectified detection signals of all of the detection regions and then providing same as an output signal (6c). The method further has the steps of illuminating the sample using the wide-field illumination device and detecting a movement in the biological sample on the basis of the output signal (6c) of the detector (3).

公开(公告)号：US10001467B2

公开(公告)日：2018-06-19

申请号：US15170508

申请日：2016-06-01

申请人： Korea Advanced Institute of Science and Technology

发明人： YongKeun Park ,  Jonghee Yoon ,  KyeoReh Lee

IPC分类号： G01N21/47 ,  G01N33/483 ,  G01N33/02 ,  G01N21/49

CPC分类号： G01N33/483 ,  G01N15/06 ,  G01N21/4795 ,  G01N21/49 ,  G01N33/02 ,  G01N2015/0065 ,  G01N2015/0687 ,  G01N2015/0693 ,  G01N2021/479 ,  G01N2201/06113 ,  G01N2201/066

摘要： An apparatus and method for detecting microbes use laser speckles. The apparatus includes a light source configured to irradiate light into a sample to detect microbes, and a measuring part configured to measure laser speckles, which are formed due to a multiple scattering of the light which is incident into the sample, every reference time and to measure concentration of the microbes contained in the sample based on temporal correlation of the measured laser speckles.

公开(公告)号：US20180059018A1

公开(公告)日：2018-03-01

申请号：US15458187

申请日：2017-03-14

申请人： SAMSUNG ELECTRONICS CO., LTD.

发明人： Jaesoong LEE

IPC分类号： G01N21/47 ,  G07D7/12 ,  G01N21/552

CPC分类号： G01N21/4788 ,  G01N21/553 ,  G01N2021/479 ,  G01N2021/4792 ,  G01N2201/0873 ,  G02B6/1226 ,  G02B6/4214 ,  G02B6/4298 ,  G07D7/12 ,  H04W12/06

摘要： An authentication structure and an authenticating method using the same are provided. The authentication structure includes a plurality of input couplers that generate surface plasmons by being selectively coupled to lights because the plurality of input couplers are different in terms of at least one of a geometric structure and an arrangement, and an output coupler that outputs a speckle pattern based on the surface plasmons.

公开(公告)号：US20170332880A1

公开(公告)日：2017-11-23

申请号：US15671763

申请日：2017-08-08

申请人： OLYMPUS CORPORATION

发明人： Ryosuke ITO

IPC分类号： A61B1/00 ,  A61B1/06 ,  A61B1/05 ,  G01N21/27 ,  G01N21/47

CPC分类号： A61B1/00009 ,  A61B1/05 ,  A61B1/0684 ,  G01N21/27 ,  G01N21/45 ,  G01N21/47 ,  G01N21/49 ,  G01N2021/479 ,  G01N2201/062

摘要： A processing apparatus includes: a light source unit configured to emit partially coherent light having a coherence length that is equal to or more than inverse of a scattering coefficient of a light scattering body and shorter than half of inverse of a reduced scattering coefficient of the light scattering body; an illumination unit configured to irradiate an illumination area on a surface of the light scattering body, with the partially coherent light emitted from the light source unit; a detection unit configured to detect, in a detection area including the illumination area, a signal of scattered and returned light from the light scattering body; and an interference component extracting unit configured to extract an interference component by excluding a noninterference component from the signal of the scattered and returned light detected by the detection unit.

公开(公告)号：US20170248518A1

公开(公告)日：2017-08-31

申请号：US15431372

申请日：2017-02-13

申请人： The General Hospital Corporation

发明人： Seemantini K. Nadkarni ,  Zeinab Hajjarian ,  David Boas ,  Sava Sakadzic ,  Stefan Carp

IPC分类号： G01N21/47 ,  G01N33/483

CPC分类号： G01N21/4788 ,  G01N15/0211 ,  G01N21/4795 ,  G01N33/4833 ,  G01N2015/0065 ,  G01N2015/0222 ,  G01N2021/479 ,  G01N2021/4792

摘要： Laser speckle microrheology is used to determine a mechanical property of a biological tissue, namely, an elastic modulus. Speckle frames may be acquired by illuminating a coherent light and capturing back-scattered rays in parallel and cross-polarized states with respect to illumination. The speckle frames may be analyzed temporally to obtain diffuse reflectance profiles (DRPs) for the parallel-polarized and cross-polarized states. A scattering characteristic of particles in the biological tissue may be determined based on the DRPs, and a displacement characteristic may be determined based at least in part on a speckle intensity autocorrelation function and the scattering characteristic. A size characteristic of scattering particles may be determined based on the DRP for the parallel polarization state. The mechanical property may be calculated using the displacement and size characteristics.

公开(公告)号：US20170230557A1

公开(公告)日：2017-08-10

申请号：US15328755

申请日：2015-06-19

申请人： SONY CORPORATION

发明人： SHUNSUKE MARUYAMA

IPC分类号： H04N5/225 ,  H01L27/146 ,  G01N21/47 ,  H04N5/33 ,  G02B3/00

CPC分类号： H04N5/2258 ,  G01N21/47 ,  G01N2021/479 ,  G02B3/0081 ,  G02B27/48 ,  G03B15/00 ,  G03B15/05 ,  G03B2215/0567 ,  H01L27/14627 ,  H01L27/14636 ,  H01L27/1464 ,  H01L27/14645 ,  H01L27/14649 ,  H04N5/2256 ,  H04N5/332

摘要： To increase the space efficiency of an imaging apparatus which deals with a speckle pattern. An imaging apparatus includes a first image sensor and a second image sensor. The first image sensor images light entering the first image sensor from an object through an optical system to generate image data of the object. The second image sensor images a speckle pattern formed by scattering of light striking the object to generate image data of the speckle pattern, the speckle pattern entering the second image sensor through the optical system. In the imaging apparatus, the first image sensor and the second image sensor are placed side by side in an optical axis direction of the optical system.

公开(公告)号：US20170143213A1

公开(公告)日：2017-05-25

申请号：US15428012

申请日：2017-02-08

申请人： The General Hospital Corporation

发明人： Seemantini K. Nadkarni

IPC分类号： A61B5/00 ,  G02B23/26 ,  G01N21/49 ,  G02B23/24 ,  A61B5/02 ,  G01N21/47

CPC分类号： A61B5/0084 ,  A61B5/0062 ,  A61B5/02007 ,  A61B5/02028 ,  A61B5/6853 ,  A61B5/6869 ,  A61B5/6876 ,  A61B5/7203 ,  A61B5/7275 ,  G01N21/474 ,  G01N21/4788 ,  G01N21/49 ,  G01N2021/4742 ,  G01N2021/479 ,  G01N2201/0683 ,  G01N2201/08 ,  G01N2201/0826 ,  G02B6/0005 ,  G02B23/2453 ,  G02B23/26

摘要： An apparatus for obtaining information regarding a biological structure(s) can include, for example a light guiding arrangement which can include a fiber through which an electromagnetic radiation(s) can be propagated, where the electromagnetic radiation can be provided to or from the structure. An at least partially reflective arrangement can have multiple surfaces, where the reflecting arrangement can be situated with respect to the optical arrangement such that the surfaces thereof each can receive a(s) beam of the electromagnetic radiations instantaneously, and a receiving arrangement(s) which can be configured to receive the reflected radiation from the surfaces which include speckle patterns.

公开(公告)号：US20150276571A1

公开(公告)日：2015-10-01

申请号：US14428506

申请日：2013-09-16

申请人： Zeinab HAJJARIAN ,  Seemantini K. NADKARNI

发明人： Zeinab Hajjarian ,  Seemantini K. Nadkarni

IPC分类号： G01N11/02 ,  G01N21/47 ,  G01N21/59 ,  G01N33/487

CPC分类号： G01N11/02 ,  G01N21/41 ,  G01N21/47 ,  G01N21/4795 ,  G01N21/59 ,  G01N33/487 ,  G01N2021/4769 ,  G01N2021/479 ,  G01N2021/4792 ,  G01N2021/4797

摘要： An algorithm for determining viscoelastic modulus of an optically scattering biofluid that takes into account variable scattering and/or absorption characteristics of the biofluid. A correction to mean square displacement value characterizing the Brownian motion of light scatterers is introduced based on a polarization-sensitive Monte-Carlo ray-tracing taking into account optical properties of the biofluid determined with the use of laser speckle rheology measurements. In contradistinction with a diffusion model, the correction-implemented determination of the viscoelastic modulus applies to a biofluid with substantially any concentration of light-scattering particles.

摘要翻译： 考虑到生物流体的可变散射和/或吸收特性的光散射生物流体的粘弹性模量的算法。 考虑到使用激光散斑流变学测量确定的生物流体的光学特性，基于偏振敏感的蒙特卡罗光线跟踪引入了表征光散射体的布朗运动的平均位移值的校正。 与扩散模型相反，校正实现的粘弹性模量的确定适用于具有基本上任何浓度的光散射颗粒的生物流体。