Orthopaedic implants having self-lubricated articulating surfaces designed to reduce wear, corrosion, and ion leaching
    9.
    发明授权
    Orthopaedic implants having self-lubricated articulating surfaces designed to reduce wear, corrosion, and ion leaching 有权
    具有自润滑关节表面的矫形植入物设计用于减少磨损,腐蚀和离子浸出

    公开(公告)号:US09523144B2

    公开(公告)日:2016-12-20

    申请号:US12059553

    申请日:2008-03-31

    Abstract: Mechanical devices such as prosthetic knees, hips, shoulders, fingers, elbows, wrists, ankles, fingers and spinal elements when implanted in the body and used as articulating elements are subjected to wear and corrosion. These prosthetic implants are usually fabricated in modular form from combinations of metallic materials such as stainless steels, Co—Cr—Mo alloys, and Ti—Al—V alloys; plastics such as ultra high molecular weight polyethylene (UHMWPE); and ceramics such as alumina and zirconia. As the articulating surfaces of these materials wear and corrode, products including plastic wear debris, metallic wear particles, and metallic ions will be released into the body, transported to and absorbed by bone, blood, the lymphatic tissue, and other organ systems. The polyethylene wear particles have been shown to produce long term bone loss and loosening of the implant. And, even very low concentrations of metallic wear particles and metallic ions are suspect in causing adverse toxic, inflammatory, and immunologic tissue reactions. This invention provides prosthetic implants having articulating surfaces that exhibit a reduced rate of release of wear debris and metal ions into the body and a method of producing such prosthetic implants.

    Abstract translation: 机械装置如假膝盖,臀部,肩部,手指,肘部,手腕,脚踝,手指和脊椎元件植入身体并用作关节元件时都会遭受磨损和腐蚀。 这些假体植入物通常由诸如不锈钢,Co-Cr-Mo合金和Ti-Al-V合金的金属材料的组合形成为模块化形式; 塑料如超高分子量聚乙烯(UHMWPE); 和陶瓷如氧化铝和氧化锆。 随着这些材料的关节表面磨损和腐蚀,包括塑料磨损碎片,金属磨损颗粒和金属离子在内的产品将被释放到体内,运送到骨骼,血液,淋巴组织和其他器官系统中并被其吸收。 已经显示聚乙烯磨损颗粒产生长期的骨丢失和植入物的松动。 而且即使非常低浓度的金属磨损颗粒和金属离子也可能引起不良的毒性,炎症和免疫组织反应。 本发明提供了具有关节表面的假体植入物,其具有降低磨损碎片和金属离子释放到体内的速率,以及生产这种假体植入物的方法。

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