知搜-全球专利检索

  1. Login
  2. Sign Up

Search Results

139 records (took 0.045 seconds)

    Electrochemical methods and devices for amending urine samples for immunosensor detection
    31.
    发明授权
    Electrochemical methods and devices for amending urine samples for immunosensor detection 有权
    电化学方法和装置，用于修复尿液样本进行免疫传感器检测

    公开(公告)号：US09488663B2

    公开(公告)日：2016-11-08

    申请号：US14206831

    申请日：2014-03-12

    Applicant: Abbott Point of Care Inc.

    Inventor： Katrina Di Tullio ,  G. Bruce Collier ,  John Lewis Emerson Campbell

    IPC: C12Q1/58 ,  G01N33/68 ,  G01N33/62 ,  G01N33/543

    CPC classification number: G01N33/54393 ,  C12Q1/58 ,  G01N33/62 ,  G01N33/6893 ,  G01N2333/47 ,  G01N2333/98 ,  G01N2800/347

    Abstract: The present invention is directed to methods and devices for amending undiluted and partially diluted urine samples in a manner suitable for performing immunoassays for target analytes, for example NGAL. Generally, the urine sample is treated with reagents including at least one of buffer materials, water soluble proteins, urease, and other interferent mitigants. These reagents control the pH of the urine sample in a manner suitable for immuno-binding reactions and ameliorate interferences, particularly during the detection step.

    Abstract translation: 本发明涉及用于修改未稀释和部分稀释的尿液样品的方法和装置，其方式适合于对目标分析物进行免疫测定，例如NGAL。 通常，尿液样品用包括缓冲材料，水溶性蛋白质，脲酶和其它干扰物中的至少一种的试剂处理。 这些试剂以适合于免疫结合反应的方式控制尿样的pH，并且改善干扰，特别是在检测步骤期间。

    UREA-BASED SYNTHETIC URINE AND METHOD OF MANUFACTURING SAME
    33.
    发明申请
    UREA-BASED SYNTHETIC URINE AND METHOD OF MANUFACTURING SAME 有权
    基于尿素的合成尿及其制备方法

    公开(公告)号：US20150338414A1

    公开(公告)日：2015-11-26

    申请号：US14817642

    申请日：2015-08-04

    Applicant: Spectrum Laboratories, LLC

    Inventor： James Matthew Stephens

    IPC: G01N33/62 ,  G01N33/70

    CPC classification number: G01N33/62 ,  G01N33/493 ,  G01N33/70 ,  G01N2496/80 ,  Y10T436/10 ,  Y10T436/147777 ,  Y10T436/171538

    Abstract: A synthetic urine solution and method of its manufacture are disclosed. The solution includes water having a pH between about 3 and about 10. The solution further includes creatinine, a means for removing bacteria from the solution so as to control or eliminate sepsis of the urine solution, preferably through the use of a biocide, and a urea-based compound. The solution exhibits a specific gravity of from 1.005 g/cm3 to 1.025 g/cm3. Additional compounds may also be included to further enhance the aesthetics or apparent authenticity of the synthetic urine.

    Abstract translation: 公开了一种合成尿液及其制造方法。 溶液包括pH在约3和约10之间的水。该溶液还包括肌酸酐，用于从溶液中除去细菌以控制或消除尿液溶液的败血症的方法，优选通过使用杀生物剂，以及 脲基化合物。 溶液的比重为1.005g / cm 3至1.025g / cm 3。 还可以包括另外的化合物以进一步增强合成尿的美观性或表观真实性。

    UREA-BASED SYNTHETIC URINE AND METHOD OF MANUFACTURING SAME
    35.
    发明申请
    UREA-BASED SYNTHETIC URINE AND METHOD OF MANUFACTURING SAME 有权
    基于尿素的合成尿及其制备方法

    公开(公告)号：US20140329327A1

    公开(公告)日：2014-11-06

    申请号：US14270546

    申请日：2014-05-06

    Applicant: James Matthew Stephens

    Inventor： James Matthew Stephens

    IPC: G01N33/70

    CPC classification number: G01N33/62 ,  G01N33/493 ,  G01N33/70 ,  G01N2496/80 ,  Y10T436/10 ,  Y10T436/147777 ,  Y10T436/171538

    Abstract: A synthetic urine solution and method of its manufacture are disclosed. The solution includes water having a pH between about 3 and about 10. The solution further includes creatinine, a means for removing bacteria from the solution so as to control or eliminate sepsis of the urine solution, preferably through the use of a biocide, and a urea-based compound. The solution exhibits a specific gravity of from 1.005 g/cm3 to 1.025 g/cm3. Additional compounds may also be included to further enhance the aesthetics or apparent authenticity of the synthetic urine.

    Abstract translation: 公开了一种合成尿液及其制造方法。 溶液包括pH在约3和约10之间的水。该溶液还包括肌酸酐，用于从溶液中除去细菌以控制或消除尿液溶液的败血症的方法，优选通过使用杀生物剂，以及 脲基化合物。 溶液的比重为1.005g / cm 3至1.025g / cm 3。 还可以包括另外的化合物以进一步增强合成尿的美观性或表观真实性。

    COMPOSITION OF HUMAN SYNTHETIC URINE
    36.
    发明申请
    COMPOSITION OF HUMAN SYNTHETIC URINE 审中-公开
    人体合成尿素的组成

    公开(公告)号：US20130234071A1

    公开(公告)日：2013-09-12

    申请号：US13417283

    申请日：2012-03-11

    Applicant: Joel David Deneau

    Inventor： Joel David Deneau

    IPC: G01N33/62

    CPC classification number: G01N33/62 ,  G01N33/96

    Abstract: This invention relates to a novel comprehensive composition comprising the major inorganic salts, urea, organic compounds, organic ammonium salts, proteins and human immuglobins present in normal human urine formulated into unisex synthetic human urine.

    Abstract translation: 本发明涉及一种新颖的综合组合物，其包含配制成中性合成人尿液的正常人尿中存在的主要无机盐，尿素，有机化合物，有机铵盐，蛋白质和人类非球蛋白。

    METHODS FOR IDENTIFYING INHIBITORS OF SOLUTE TRANSPORTERS
    40.
    发明申请
    METHODS FOR IDENTIFYING INHIBITORS OF SOLUTE TRANSPORTERS 有权
    用于鉴定溶解性传感器的抑制剂的方法

    公开(公告)号：US20100190796A1

    公开(公告)日：2010-07-29

    申请号：US12514992

    申请日：2007-11-16

    Applicant: Alan S. Verkman ,  Marc Harris Levin

    Inventor： Alan S. Verkman ,  Marc Harris Levin

    IPC: A61K31/502 ,  C12Q1/02 ,  A61K31/4184

    CPC classification number: G01N33/5026 ,  G01N33/62 ,  G01N33/6872 ,  G01N33/80 ,  G01N2500/10

    Abstract: Provided herein are methods for identifying and characterizing agents that alter the volume of a cell. Methods are provided for rapid screening and identification of an agent that alters the capability of a small, neutrally charged solute transporter to transport the solute across a cell membrane. The methods described herein may be used to identify and characterize inhibitors of urea transporters, to identify and characterize inhibitors of aquaporins, and to identify and characterize inhibitors of other small, neutrally charged solutes such as glucose.

    Abstract translation: 本文提供了用于鉴定和表征改变细胞体积的试剂的方法。 提供了用于快速筛选和鉴定改变小的中性带电溶质转运蛋白将细胞穿过细胞膜输送溶质的能力的方法。 本文描述的方法可用于鉴定和表征尿素转运蛋白的抑制剂，以鉴定和表征水通道蛋白的抑制剂，以及鉴定和表征其它小的，中性电荷的溶质如葡萄糖的抑制剂。

Patent Agency Ranking