公开(公告)号：US20190241912A1

公开(公告)日：2019-08-08

申请号：US16320362

申请日：2017-07-25

Applicant: The Regents of the University of California

Inventor： Philipp Zerbe ,  Sibongile Mafu

IPC: C12P5/00 ,  C12N9/88 ,  A61K31/015 ,  C07C13/47 ,  C12N15/52 ,  C12N15/70 ,  C12N15/81

CPC classification number: C12P5/00 ,  A61K31/015 ,  C07C13/47 ,  C07C2602/26 ,  C12N9/88 ,  C12N15/52 ,  C12N15/70 ,  C12N15/81 ,  C12P5/007 ,  C12P17/06 ,  C12Y402/03

Abstract: Diterpene synthases and methods of their use are described herein.

公开(公告)号：US20160369026A1

公开(公告)日：2016-12-22

申请号：US15257634

申请日：2016-09-06

Applicant: PROMERUS, LLC

Inventor： ANDREW BELL ,  LEAH LANGSDORF ,  OLEKSANDR BURTOVYY

IPC: C08F232/08 ,  B01D61/36 ,  C07C13/68 ,  C07C13/42 ,  C07C13/47 ,  B01D71/82 ,  C07C13/40

CPC classification number: C08F232/08 ,  B01D61/362 ,  B01D67/0009 ,  B01D69/02 ,  B01D69/08 ,  B01D69/12 ,  B01D71/26 ,  B01D71/44 ,  B01D71/76 ,  B01D71/82 ,  B01D2325/20 ,  C07C13/40 ,  C07C13/42 ,  C07C13/465 ,  C07C13/47 ,  C07C13/50 ,  C07C13/54 ,  C07C13/547 ,  C07C13/573 ,  C07C13/605 ,  C07C13/61 ,  C07C13/615 ,  C07C13/64 ,  C07C13/68 ,  C07C29/76 ,  C07C37/82 ,  C07C2602/42 ,  C07C2603/10 ,  C07C2603/28 ,  C07C2603/62 ,  C07C2603/64 ,  C07C2603/66 ,  C07C2603/74 ,  C07C2603/90 ,  C07C2603/91 ,  Y02E50/17 ,  C07C31/12 ,  C07C39/04

Abstract: A variety of polycycloalkyl polynorbornene monomers and polymers derived therefrom are disclosed and claimed. The polymers and copolymers as disclosed herein are useful for forming pervaporation membranes, among other uses.

Abstract translation: 公开和要求保护各种聚环烷基聚降冰片烯单体和衍生自其的聚合物。 除了其它用途之外，本文公开的聚合物和共聚物可用于形成渗透蒸发膜。

公开(公告)号：US5900517A

公开(公告)日：1999-05-04

申请号：US695400

申请日：1996-08-12

Applicant: Paolo Biagini ,  Roberto Santi ,  Giampiero Borsotti ,  Gabriele Lugli ,  Viviano Banzi

Inventor： Paolo Biagini ,  Roberto Santi ,  Giampiero Borsotti ,  Gabriele Lugli ,  Viviano Banzi

IPC: B01J27/16 ,  B01J31/22 ,  C07B61/00 ,  C07C2/00 ,  C07C13/28 ,  C07C13/32 ,  C07C13/36 ,  C07C13/39 ,  C07C13/45 ,  C07C13/47 ,  C07C13/52 ,  C07C13/615 ,  C07C1/32

CPC classification number: C07C13/32 ,  C07C13/52 ,  C07C2102/14 ,  C07C2102/30 ,  C07C2102/32

Abstract: Cyclopentadienyl derivatives are described having general formula (I) ##STR1## where R, R.sub.1, R.sub.2, R.sub.4, equivalent to or different from one another, are selected from: --H, alkyl radicals having a number of carbon atoms from 1 to 5, cycloalkyl radicals having a number of carbon atoms from 5 to 8, aryl and alkylaryl radicals having a number of carbon atoms from 6 to 8, aralkyl radicals having a number of carbon atoms from 7 to 9; n is an integer from 2 to 18; with the proviso that the number of R different from H does not exceed 2; with the exclusion of the compound having n=3, R.dbd.R.sub.1 .dbd.R.sub.2 .dbd.R.sub.4 .dbd.H. The invention a-so describes the process for the preparation of the above-mentioned cyclopentadienyl derivatives.

Abstract translation: 描述了具有通式（I）的环戊二烯基衍生物，其中R，R 1，R 2，R 4彼此相当或不同，选自：-H，具有1至5个碳原子数的烷基，环烷基具有 5至8个碳原子数，6至8个碳原子数的芳基和烷芳基，7至9个碳原子的芳烷基; n是2至18的整数; 条件是与H不同的R数不超过2; 排除n = 3的化合物，R = R 1 = R 2 = R 4 = H。 本发明a-描述了制备上述环戊二烯基衍生物的方法。

公开(公告)号：US5124464A

公开(公告)日：1992-06-23

申请号：US366605

申请日：1989-06-15

Applicant: Myron Rosenblum ,  Stephen A. Matchett

Inventor： Myron Rosenblum ,  Stephen A. Matchett

IPC: C07C13/47 ,  C07F17/02

CPC classification number: C07F17/02 ,  C07C13/47 ,  C07C2101/10

Abstract: This invention describes a novel method of preparing metallocene compounds. The invention is based on synthesis of novel bis cyclopentadienides that, under appropriate conditions, will either encapsulate a transition metal to produce a metallocene such as ferrocene, or ferrocene derivative, or will yield a polymeric metallocene. Compounds produced by this process are useful as catalysts in propulsion systems, or as anti-knock compounds in gasolines.

Abstract translation: 本发明描述了一种制备茂金属化合物的新方法。 本发明基于合成新的双环戊二烯，其在合适的条件下将包封过渡金属以产生茂金属如二茂铁或二茂铁衍生物，或将产生聚合金属茂。 通过该方法生产的化合物可用作推进系统中的催化剂，或作为汽油中的抗敲除化合物。

公开(公告)号：US4666941A

公开(公告)日：1987-05-19

申请号：US675700

申请日：1984-11-28

Applicant: Braham Shroot ,  Jacques Eustache ,  Martine Bouclier

Inventor： Braham Shroot ,  Jacques Eustache ,  Martine Bouclier

IPC: A61K8/00 ,  A01N35/04 ,  A61K8/30 ,  A61K8/33 ,  A61K8/49 ,  A61K8/67 ,  A61K31/015 ,  A61K31/045 ,  A61K31/075 ,  A61K31/10 ,  A61K31/11 ,  A61K31/12 ,  A61K31/13 ,  A61K31/135 ,  A61K31/165 ,  A61K31/19 ,  A61K31/215 ,  A61K31/22 ,  A61K31/235 ,  A61K31/275 ,  A61K31/425 ,  A61K31/695 ,  A61K31/70 ,  A61K31/7024 ,  A61P3/02 ,  A61P17/16 ,  A61P29/00 ,  A61P35/02 ,  A61P37/08 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q19/00 ,  C07C1/00 ,  C07C2/00 ,  C07C13/32 ,  C07C13/47 ,  C07C13/48 ,  C07C15/24 ,  C07C17/00 ,  C07C25/22 ,  C07C27/00 ,  C07C29/32 ,  C07C33/14 ,  C07C33/18 ,  C07C33/34 ,  C07C33/50 ,  C07C39/14 ,  C07C39/17 ,  C07C39/42 ,  C07C41/00 ,  C07C43/164 ,  C07C43/168 ,  C07C43/20 ,  C07C43/307 ,  C07C45/00 ,  C07C45/30 ,  C07C45/61 ,  C07C47/235 ,  C07C47/546 ,  C07C49/76 ,  C07C49/782 ,  C07C49/792 ,  C07C51/353 ,  C07C63/33 ,  C07C63/34 ,  C07C63/36 ,  C07C63/44 ,  C07C63/49 ,  C07C65/01 ,  C07C65/11 ,  C07C65/17 ,  C07C65/26 ,  C07C67/00 ,  C07C69/007 ,  C07C69/035 ,  C07C69/157 ,  C07C69/24 ,  C07C69/76 ,  C07C69/84 ,  C07C69/90 ,  C07C69/94 ,  C07C225/22 ,  C07C233/65 ,  C07C235/46 ,  C07C235/52 ,  C07C237/30 ,  C07C237/36 ,  C07C237/42 ,  C07C253/00 ,  C07C255/50 ,  C07C255/52 ,  C07C313/00 ,  C07C319/02 ,  C07C319/20 ,  C07C321/26 ,  C07C321/28 ,  C07C323/19 ,  C07C323/22 ,  C07C323/38 ,  C07C323/62 ,  C07C325/00 ,  C07C327/22 ,  C07D263/10 ,  C07D295/00 ,  C07D295/02 ,  C07F7/18 ,  C07H13/08 ,  C11D3/48

CPC classification number: A61Q19/00 ,  A61K8/671 ,  C07C323/00 ,  C07C33/34 ,  C07C39/17 ,  C07C43/164 ,  C07C45/305 ,  C07C47/546 ,  C07C49/792 ,  C07C63/49 ,  C07C65/17 ,  C07C65/26 ,  A61Q17/02 ,  A61Q19/007 ,  A61Q19/008 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q7/00 ,  Y10S514/859 ,  Y10S514/863

Abstract: New polysubstituted derivatives of naphtalene.These derivatives correspond to the following formula: ##STR1## in which: R.sub.1 to R.sub.4 is H or CH.sub.3R.sub.5 is ##STR2## or (iv) the radical: 2-oxazolinyl m is 0 or 1R.sub.8 is H, alkyl, OR.sub.11, R.sub.11 being H, alkyl or ##STR3## R.sub.13 being alkyl or aryl or R.sub.8 is ##STR4## when m=1, r' and r" representing H, alkyl mono or polyhydroxyalkyl, aryl or a heterocycle when they are taken together, R.sub.9 is H or alkyl, R.sub.10 is H, alkyl and the acetals of the said compounds, ##STR5## --OR.sub.14, R.sub.14 being H, alkyl, mono or polyhydroxyalkyl, aryl or aralkyl a rest of a sugar or represents ##STR6## P being 0, 1, 2, or 3 R.sub.6 represents a hydrogen atom or a lower alkyl radical,R.sub.7 represents H, alkyl, halogen, hydroxyl, sulfydryl, alkoxy, alkylthio, acyloxy, acylthio, acylamino or primary, secondary or tertiary amino and the salts of the said compounds.These compounds find an application in the cosmetic and pharmaceutical fields.

Abstract translation: 萘的新型多取代衍生物。 （I）其中：R 1至R 4为H或CH 3 R 5是（ⅰ）CN（ⅱ）ι（ⅲ）或（ⅳ）基团：2 - 恶唑啉基m是0或1个R8是H，烷基，OR11，R11是H，烷基或者R13是烷基或芳基，或R8是当m = 1时，r'和r“代表H，烷基 单或多羟基烷基，芳基或杂环，当它们一起时，R 9为H或烷基，R 10为H，烷基和所述化合物的缩醛，-OR14，R14为H，烷基，单或多羟基烷基，芳基 或芳烷基，其余的糖或代表P为0,1,2或3的R 6表示氢原子或低级烷基，R 7表示H，烷基，卤素，羟基，巯基，烷氧基，烷硫基，酰氧基 ，酰硫基，酰氨基或伯，仲或叔氨基和所述化合物的盐。 这些化合物在化妆品和药物领域中得到应用。

公开(公告)号：US4665275A

公开(公告)日：1987-05-12

申请号：US745576

申请日：1985-06-17

Applicant: Toshio Yoshida ,  Harumichi Watanabe

Inventor： Toshio Yoshida ,  Harumichi Watanabe

IPC: C10M105/06 ,  C07C13/47

CPC classification number: C10M105/06

Abstract: A thermal medium oil comprising at least one monosubstituted naphthalene derivative such as .beta.-(1,1-dimethyloctyl) naphthalene, .beta.-(1,1-dimethylhexyl) naphthalene and 2-t.-amylnaphthalene.

Abstract translation: 包含至少一种单取代萘衍生物如β-（1,1-二甲基辛基）萘，β-（1,1-二甲基己基）萘和2-t.-戊基萘的热介质油。

公开(公告)号：US4604491A

公开(公告)日：1986-08-05

申请号：US674881

申请日：1984-11-26

Applicant: Hans Dressler ,  Albert A. Meilus

Inventor： Hans Dressler ,  Albert A. Meilus

IPC: C10M105/06 ,  C10N40/08 ,  C10N50/10 ,  C07C13/47 ,  C07C15/20

CPC classification number: C10M105/06 ,  C10M2203/06

Abstract: Synthetic base oils for functional fluids and greases are provided comprising a mixture of monoalkylated naphthalenes and polyalkylated naphthalenes, said naphthalenes represented by the formula: ##STR1## wherein the R' groups are independently selected from H and methyl, the monoalkylated naphthalenes have three R groups which are H and one R group which is a 12-26 carbon alkyl, the polyalkylated naphthalenes have from two to four R groups which are 12-26 carbon alkyl and any remainder R groups H, and the weight ratio of monoalkylated naphthalenes to polyalkylated naphthalenes is from 5:95 to 70:30 when the average alkyl group is C.sub.12 -C.sub.16 and from 5:95 to 99:1 when the average alkyl group is C.sub.17 -C.sub.26. In the preferred mixture, the polyalkylated naphthalenes have a numerical ratio of .alpha./.beta. substitution of from 50/50 to 10/90 when the R' groups are both H.

Abstract translation: 提供功能性流体和油脂的合成基础油，其包含单烷基化萘和多烷基化萘的混合物，所述萘由下式表示：其中R'基团独立地选自H和甲基，单烷基化萘具有三个R基团 其为H和一个R基团，其为12-26个碳烷基，所述多烷基化萘具有2至4个R基团，其为12-26个碳原子的烷基和任何其余的R基团H，并且单烷基化萘与多烷基化萘的重量比 当平均烷基为C 17 -C 26时，当平均烷基为C 12 -C 16和5:95至99:1时，为5:95至70:30。 在优选的混合物中，当R'基团均为H时，多烷基化萘的α/β取代数值为50/50至10/90。

公开(公告)号：US4386007A

公开(公告)日：1983-05-31

申请号：US213517

申请日：1980-12-05

Applicant: Joachim Krause ,  Michael Romer ,  Ludwig Pohl

Inventor： Joachim Krause ,  Michael Romer ,  Ludwig Pohl

IPC: C07C69/035 ,  C07C1/00 ,  C07C13/28 ,  C07C13/47 ,  C07C13/48 ,  C07C15/24 ,  C07C17/00 ,  C07C17/12 ,  C07C17/16 ,  C07C17/18 ,  C07C17/20 ,  C07C17/26 ,  C07C22/02 ,  C07C22/04 ,  C07C22/08 ,  C07C23/00 ,  C07C23/18 ,  C07C23/36 ,  C07C25/18 ,  C07C25/22 ,  C07C29/00 ,  C07C29/145 ,  C07C41/00 ,  C07C43/20 ,  C07C43/21 ,  C07C43/225 ,  C07C43/235 ,  C07C45/46 ,  C07C45/75 ,  C07C49/67 ,  C07C49/83 ,  C07C51/08 ,  C07C67/00 ,  C07C69/14 ,  C07C69/24 ,  C07C201/00 ,  C07C205/05 ,  C07C253/00 ,  C07C255/47 ,  C07C255/50 ,  C07C255/52 ,  C09K19/00 ,  C09K19/32 ,  C09K19/46 ,  C09K3/34 ,  G02F1/13

CPC classification number: C07C17/208 ,  C07C13/47 ,  C07C17/12 ,  C07C17/16 ,  C07C17/18 ,  C07C17/263 ,  C07C22/08 ,  C07C25/22 ,  C07C255/00 ,  C07C29/00 ,  C07C29/145 ,  C07C43/21 ,  C07C45/46 ,  C07C45/75 ,  C07C49/67 ,  C07C49/83 ,  C07C51/08 ,  C09K19/322 ,  C07C2102/10 ,  C09K2019/324 ,  C09K2019/325

Abstract: Liquid crystalline naphthalene derivatives of the formula ##STR1## wherein ring A is 1,4-phenylene, trans-1,4-cyclohexylene or 1,4-cyclohex-1-enylene and ring system BC is 2,6-naphthylene, 3,4-dihydro-2,6-naphthylene or 1,2,3,4-tetrahydro-2,6-naphthylene, with the proviso that A is not 1,4-phenylene when BC is 2,6-naphthylene; and R.sub.1 and R.sub.2, which are identical or different, are each alkyl of up to 8 C atoms or, when the rings to which they are bonded are aromatic, also can be alkoxy, alkanoyloxy or alkoxycarbonyloxy having up to 8 C atoms in each case; or one of R.sub.1 and R.sub.2 also can be CN, halogen, CF.sub.3 or NO.sub.2 are valuable components for liquid crystalline dielectrics.

Abstract translation: 其中环A为1,4-亚苯基，反式-1,4-亚环己基或1,4-环己-1-烯和环系BC的式IMA图的液晶萘衍生物为2,6-亚萘基， 4-二氢-2,6-亚萘基或1,2,3,4-四氢-2,6-亚萘基，条件是当BC为2,6-亚萘基时，A不为1,4-亚苯基; 并且相同或不同的R 1和R 2各自为至多8个C原子的烷基，或者当它们键合的环是芳族时，也可以是具有至多8个C原子的烷氧基，烷酰氧基或烷氧羰基氧基 ; 或者R1和R2中的一个也可以是CN，卤素，CF 3或NO 2是液晶电介质的有价值的组分。

公开(公告)号：US11525036B2

公开(公告)日：2022-12-13

申请号：US17072771

申请日：2020-10-16

Applicant: International Business Machines Corporation ,  AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Mareva B. Fevre ,  James L. Hedrick ,  Nathaniel H. Park ,  Victoria A. Piunova ,  Pang Kern Jeremy Tan ,  Chuan Yang ,  Yi Yan Yang

IPC: A61K31/66 ,  A61K31/787 ,  A61P31/06 ,  C08G73/02 ,  A61K31/166 ,  C07C13/47

Abstract: Techniques regarding killing of a pathogen with one or more ionene compositions having antimicrobial functionality are provided. For example, one or more embodiments can comprise a method, which can comprise contacting a Mycobacterium tuberculosis microbe with a chemical compound. The chemical compound can comprise an ionene unit. Also, the ionene unit can comprise a cation distributed along a molecular backbone. The ionene unit can have antimicrobial functionality. The method can further comprise electrostatically disrupting a membrane of the Mycobacterium tuberculosis microbe in response to the contacting.

公开(公告)号：US10099975B2

公开(公告)日：2018-10-16

申请号：US14913807

申请日：2014-08-11

Applicant: MERCK PATENT GMBH

Inventor： Christian Jasper ,  Constanze Brocke ,  Detlef Pauluth ,  Volker Reiffenrath ,  Atsutaka Manabe

IPC: C07C15/18 ,  C07C13/47 ,  C07C13/573 ,  C07C15/24 ,  C07C25/24 ,  C07D213/24 ,  C07D307/36 ,  C07D307/38 ,  C07D333/10 ,  C07D333/12 ,  C09K19/18 ,  C09K19/32 ,  C09K19/34

Abstract: Compounds of formula I their use in liquid-crystalline media, for example, for the phase shifting of microwaves for tunable phased-array antennae, and their use for high-frequency components, in particular antennae, especially for the gigahertz range.