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    Biphenyl derivatives substituted with an aromatic or heteroaromatic radical, and pharmaceutical and cosmetic compositions containing them
    9.
    发明授权
    Biphenyl derivatives substituted with an aromatic or heteroaromatic radical, and pharmaceutical and cosmetic compositions containing them 失效
    被芳族或杂芳族基团取代的联苯衍生物，以及含有它们的药物和化妆品组合物

    公开(公告)号：US06649612B1

    公开(公告)日：2003-11-18

    申请号：US09932938

    申请日：2001-08-21

    申请人： Jean-Michel Bernardon ,  Philippe Nedoncelle

    发明人： Jean-Michel Bernardon ,  Philippe Nedoncelle

    IPC分类号： A61K748

    CPC分类号： C07C65/26 ,  C07C65/17 ,  C07C69/94

    摘要： Compounds of formula (I): in which: Ar represents an aromatic or a heteroaromatic radical optionally substituted, in particular, with an alkyl or a carboxyl group, R2 and R3 represent, in particular, H or alkyl, or R2 and R3, taken together, form a 5- or 6-membered ring, R4 and R5 represent, in particular, H or halogen, R6 represents, in particular, H or lower alkyl, and the salts of the compounds of formula (I). These compounds can be used in particular in the treatment of dermatological complaints associated with a keratinization disorder, and for combating ageing of the skin.

    摘要翻译： 式（I）化合物：其中：Ar表示任选被烷基或羧基取代的芳香族或杂芳族基，R2和R3特别表示H或烷基，或R 2和R 3一起 形成5-或6-元环，R 4和R 5特别表示H或卤素，R 6表示特别是H或低级烷基，以及式（I）化合物的盐。这些化合物可以是 特别用于治疗与角质化障碍相关的皮肤病学反应，并用于对抗皮肤老化。

    CONDENSATES
    10.
    发明申请
    CONDENSATES 失效
    冷凝

    公开(公告)号：US20020077254A1

    公开(公告)日：2002-06-20

    申请号：US09732880

    申请日：2000-12-11

    发明人： Spencer Edwin Taylor ,  Michael John Wilson

    IPC分类号： C10M129/14 ,  C10L001/18 ,  C07C069/94

    CPC分类号： C10M159/22 ,  B01D17/045 ,  B01D17/047 ,  C07C65/17 ,  C07C69/94 ,  C10L1/1981 ,  C10L10/04 ,  C10M145/20 ,  C10M2209/00 ,  C10M2209/02 ,  C10M2209/10 ,  C10M2209/101 ,  C10N2240/10 ,  C10N2240/101 ,  C10N2240/104 ,  C10N2240/106

    摘要： A cyclic compound comprising m units of the formula Ia. 1 and n units of the formula (Ib) 2 joined together to form a ring, wherein Y and y2 are divalent bridging groups which may be the same or different in each unit; R0 is H or (C1-C6) alkyl or is a metal or ammonium cation; R5 is H or (C1-C60) alkyl or OH group; j is 1 or 2; R3 is hydrogen, a hydrocarbyl or a hetero-substituted hydrocarbyl group; each of R1, R2 and R4, which may be the same or different, is hydroxyl, hydrogen, hydrocarbyl or hetero-substituted hydrocarbyl, with the provisos that i) at least one of R1, R2, R4 is hydroxyl, and mnulln is 4 to 20, m is 1-8 and n is at least 3, and ii) in formula Ia at least one OH group is in the meta or para position to the COOR0 group and/or at least one R5 group is OH.

    摘要翻译： 包含m个式Ia化合物的环状化合物。 和式（Ib）的n个单元连接在一起形成环，其中Y和y2是每个单元可以相同或不同的二价桥基; R 0是H或（C 1 -C 6）烷基或是金属或铵阳离子; R5是H或（C1-C60）烷基或OH基; j为1或2; R3是氢，烃基或杂取代的烃基; R 1，R 2和R 4各自可以相同或不同，是羟基，氢，烃基或杂取代的烃基，条件是i）R 1，R 2，R 4中的至少一个是羟基，m + n 为4至20，m为1-8且n为至少3，和ii）在式Ia中，至少一个OH基位于COOR0基团的间位或对位，和/或至少一个R 5基团为OH。