公开(公告)号：US20240306490A1

公开(公告)日：2024-09-12

申请号：US18645413

申请日：2024-04-25

Applicant: IDEMITSU KOSAN CO.,LTD.

Inventor： Ryota TAKAHASHI ,  Tomoki KATO ,  Hirokatsu ITO ,  Masahiro KAWAMURA ,  Masakazu FUNAHASHI ,  Hiroyuki SAITO ,  Yuichiro KAWAMURA ,  Yoshiaki TAKAHASHI ,  Tetsuya MASUDA ,  Hitoshi KUMA

IPC: H10K85/60 ,  C07C211/61 ,  C07D209/86 ,  C07D213/16 ,  C07D213/22 ,  C07D231/56 ,  C07D235/18 ,  C07D237/08 ,  C07D239/26 ,  C07D239/74 ,  C07D241/12 ,  C07D251/24 ,  C07D307/92 ,  C07D333/74 ,  C07D333/76 ,  C07D471/04 ,  C09K11/06 ,  H10K50/11 ,  H10K50/15 ,  H10K50/16 ,  H10K50/165 ,  H10K50/18 ,  H10K71/00 ,  H10K71/16 ,  H10K101/00 ,  H10K101/10 ,  H10K102/00

CPC classification number: H10K85/624 ,  C07C211/61 ,  C07D209/86 ,  C07D213/16 ,  C07D213/22 ,  C07D231/56 ,  C07D235/18 ,  C07D237/08 ,  C07D239/26 ,  C07D239/74 ,  C07D241/12 ,  C07D251/24 ,  C07D307/92 ,  C07D333/74 ,  C07D333/76 ,  C07D471/04 ,  C09K11/06 ,  H10K85/623 ,  H10K85/633 ,  H10K85/654 ,  C07C2603/18 ,  C07C2603/52 ,  C07C2603/94 ,  C07C2603/97 ,  C09K2211/1018 ,  H10K50/11 ,  H10K50/15 ,  H10K50/156 ,  H10K50/165 ,  H10K50/166 ,  H10K50/18 ,  H10K71/00 ,  H10K71/164 ,  H10K2101/10 ,  H10K2101/27 ,  H10K2102/351

Abstract: Compounds of formulae (2-7) or (2-9) are provided:




Also provided are organic electroluminescence (EL) devices containing the compounds having a high emission efficiency when operated at low voltage and a long lifetime and electronic devices including such organic EL devices.

公开(公告)号：US20240294504A1

公开(公告)日：2024-09-05

申请号：US18663765

申请日：2024-05-14

Applicant: The Broad Institute, Inc. ,  THE GENERAL HOSPITAL CORPORATION

Inventor： Deborah HUNG ,  Christoph ERNST ,  Tomohiko KAWATE

IPC: C07D401/14 ,  A61K31/085 ,  A61K31/135 ,  A61K31/40 ,  A61K31/415 ,  A61K31/454 ,  A61K31/4545 ,  A61K31/505 ,  A61P31/04 ,  C07C43/225 ,  C07D207/34 ,  C07D213/73 ,  C07D213/74 ,  C07D231/12 ,  C07D239/26 ,  C07D401/04

CPC classification number: C07D401/14 ,  A61K31/085 ,  A61K31/135 ,  A61K31/40 ,  A61K31/415 ,  A61K31/454 ,  A61K31/4545 ,  A61K31/505 ,  A61P31/04 ,  C07C43/225 ,  C07D207/34 ,  C07D213/73 ,  C07D213/74 ,  C07D231/12 ,  C07D239/26 ,  C07D401/04

Abstract: Compounds, pharmaceutical compositions, and methods of use of said compounds and pharmaceutical compositions for treating or preventing a microbial infection or for inducing antimicrobial activity against a microbial infection.

公开(公告)号：US12065437B2

公开(公告)日：2024-08-20

申请号：US17192985

申请日：2021-03-05

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Guanglin Luo ,  Carolyn Diane Dzierba ,  John E. Macor

IPC: C07D471/04 ,  A61K31/4427 ,  A61K31/50 ,  A61P25/28 ,  C07C233/25 ,  C07D213/30 ,  C07D213/34 ,  C07D213/57 ,  C07D213/61 ,  C07D213/64 ,  C07D213/73 ,  C07D213/74 ,  C07D213/75 ,  C07D213/80 ,  C07D215/14 ,  C07D237/08 ,  C07D239/26 ,  C07D309/18 ,  C07D309/22 ,  C07D401/04 ,  C07D401/14 ,  C07D413/10

CPC classification number: C07D471/04 ,  A61K31/4427 ,  A61K31/50 ,  A61P25/28 ,  C07C233/25 ,  C07D213/30 ,  C07D213/34 ,  C07D213/57 ,  C07D213/61 ,  C07D213/64 ,  C07D213/73 ,  C07D213/74 ,  C07D213/75 ,  C07D213/80 ,  C07D215/14 ,  C07D237/08 ,  C07D239/26 ,  C07D309/18 ,  C07D309/22 ,  C07D401/04 ,  C07D401/14 ,  C07D413/10

Abstract: The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.

公开(公告)号：US20240270697A1

公开(公告)日：2024-08-15

申请号：US18563596

申请日：2022-01-25

Applicant: LT MATERIALS CO., LTD.

Inventor： Jun-Tae MO ,  Yong-Hui LEE ,  Dong-Jun KIM

IPC: C07D239/26 ,  C07D239/74 ,  C07D251/24 ,  C07D403/06 ,  C07D403/14 ,  C07D405/04 ,  C07D405/12 ,  C07D405/14 ,  C07D409/04 ,  C07D409/12 ,  C07D487/04 ,  C07D491/048 ,  C07D495/04 ,  H10K50/11 ,  H10K85/60

CPC classification number: C07D239/26 ,  C07D239/74 ,  C07D251/24 ,  C07D403/06 ,  C07D403/14 ,  C07D405/04 ,  C07D405/12 ,  C07D405/14 ,  C07D409/04 ,  C07D409/12 ,  C07D487/04 ,  C07D491/048 ,  C07D495/04 ,  H10K50/11 ,  H10K85/636 ,  H10K85/654 ,  H10K85/6572 ,  H10K85/6574

Abstract: The present application provides a heterocyclic compound and an organic light emitting device in which the heterocyclic compound is contained in an organic material layer.

公开(公告)号：US20240246905A1

公开(公告)日：2024-07-25

申请号：US18290241

申请日：2022-05-10

Applicant: University of Leicester

Inventor： Steven D. Bull ,  Liam J. Stephens

IPC: C07C291/10 ,  A61K31/277 ,  A61K31/4409 ,  A61K31/505 ,  A61P31/04 ,  C07D213/57 ,  C07D239/26

CPC classification number: C07C291/10 ,  A61K31/277 ,  A61K31/4409 ,  A61K31/505 ,  A61P31/04 ,  C07D213/57 ,  C07D239/26 ,  C07C2601/16

Abstract: Compounds of formula (I) or formula (II) are disclosed:




Wherein Y1, Y2 and Y3 are independently selected from C—R1 or N. Such compounds find use as antibiotics and antifungals.

公开(公告)号：US20240174612A1

公开(公告)日：2024-05-30

申请号：US18386724

申请日：2023-11-03

Applicant: VIRGINIA COMMONWEALTH UNIVERSITY ,  IllExcor Therapeutics, LLC ,  KING ABDULAZIZ UNIVERSITY ,  CHILDREN'S HOSPITAL OF PHILADELPHIA (CHOP)

Inventor： Martin SAFO ,  Yan ZHANG ,  Andrew FLEISCHMAN ,  David LIGHT ,  Moustafa EL-ARABY ,  Abdelsattar OMAR ,  Osheiza ABDULMALIK

IPC: C07D213/30 ,  A61P7/06 ,  C07D239/26

CPC classification number: C07D213/30 ,  A61P7/06 ,  C07D239/26

Abstract: Compounds and methods for preventing and/or treating one or more symptoms of sickle cell diseases (SCD) by administering at least one of the compounds are provided. The compounds are chemically modified to increase bioavailability and activity, e.g., so that the compounds prevent adhesion and sickling of red blood cells (RBCs).

公开(公告)号：US20240138255A1

公开(公告)日：2024-04-25

申请号：US18265294

申请日：2022-02-28

Applicant: LG CHEM, LTD.

Inventor： Dong Uk HEO ,  Heekyung YUN ,  Miyeon HAN ,  Jae Tak LEE ,  Jung Min YOON ,  Hoyoon PARK ,  Sung Kil HONG

IPC: H10K85/60 ,  C07D237/08 ,  C07D239/26 ,  C07D239/74 ,  C07D241/12 ,  C07D251/24 ,  C07D257/08 ,  C09K11/06

CPC classification number: H10K85/654 ,  C07D237/08 ,  C07D239/26 ,  C07D239/74 ,  C07D241/12 ,  C07D251/24 ,  C07D257/08 ,  C09K11/06 ,  H10K85/626 ,  H10K50/16

Abstract: Provided is a compound of Chemical Formula 1 or 2:






wherein: R1 to R4 are each independently hydrogen or deuterium; n1 to n4 are an integer of 1 to 4; L1 and L2 are each independently a direct bond or a substituted or unsubstituted C6-60 arylene; and Ar1 and Ar2 are each independently a substituent of Chemical Formula 3:










wherein X1 to X5 are each independently N or C(R5), wherein at least two of X1 to X5 are N; and each R5 is independently hydrogen, deuterium, a substituted or unsubstituted C1-20 alkyl, a substituted or unsubstituted C6-60 aryl, or a substituted or unsubstituted C2-60 heteroaryl containing at least one of N, O and S, or two adjacent R5s combine to form a benzene ring; and an organic light emitting device including the same. The device exhibits significantly superior efficiency and lifespan.

公开(公告)号：US11968893B2

公开(公告)日：2024-04-23

申请号：US17698247

申请日：2022-03-18

Applicant: UDC IRELAND LIMITED

Inventor： Thomas Schafer ,  Patrice Bujard ,  Jonathan Rogers ,  Kristina Bardon

IPC: H10K85/60 ,  C07D239/26 ,  C07D403/10 ,  C09K11/06 ,  H10K50/11

CPC classification number: H10K85/654 ,  C07D239/26 ,  C07D403/10 ,  C09K11/06 ,  C09K2211/1018 ,  H10K50/11 ,  H10K85/6565

Abstract: Disclosed are electroluminescent devices that comprise organic layers that contain certain organic compounds containing one ore more pyrimidine moieties. The organic compounds containing one ore more pyrimidine moieties are suitable components of blue-emitting, durable, organo-electroluminescent layers. The electroluminescent devices may be employed for full color display panels in for example mobile phones, televisions and personal computer screens.

公开(公告)号：US11952344B2

公开(公告)日：2024-04-09

申请号：US17754118

申请日：2020-09-25

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Yuya Oguro ,  Makoto Kamata ,  Shuhei Ikeda ,  Takeshi Wakabayashi ,  Norihito Tokunaga ,  Taku Kamei ,  Mitsuhiro Ito ,  Shigemitsu Matsumoto ,  Hirotaka Kamitani ,  Takaharu Hirayama ,  Toshio Tanaka ,  Hiroshi Banno ,  Nobuyuki Takakura ,  Jinichi Yonemori ,  Takuya Fujimoto

IPC: C07D213/61 ,  A61K31/444 ,  A61K31/495 ,  A61P25/00 ,  A61P29/00 ,  C07D211/04 ,  C07D213/65 ,  C07D213/68 ,  C07D221/04 ,  C07D237/08 ,  C07D239/26 ,  C07D239/34 ,  C07D333/38 ,  C07D401/12 ,  C07D405/02

CPC classification number: C07D211/04 ,  C07D237/08 ,  C07D239/26 ,  C07D405/02

Abstract: Provided is a heterocyclic compound that can have an antagonistic action on an NMD A receptor containing the NR2B subunit and that is expected to be useful as a prophylactic or therapeutic agent for depression, bipolar disorder, migraine, pain, peripheral symptoms of dementia and the like. A compound represented by the formula (I), wherein each symbol is as defined in the DESCRIPTION, or a salt thereof.

公开(公告)号：US20240049595A1

公开(公告)日：2024-02-08

申请号：US18039739

申请日：2021-12-02

Applicant: Hodogaya Chemical Co., Ltd.

Inventor： Takeshi Yamamoto ,  Kouki Kase ,  Yuta Hirayama ,  Kyung-Hwa Park ,  Shuichi Hayashi

IPC: H10K85/60 ,  C07D239/26 ,  C09K11/06 ,  C07D213/16 ,  C07D405/10 ,  C07D471/04 ,  C07D409/14 ,  C07D405/04 ,  C07D409/10 ,  C07D413/10 ,  C07D417/10 ,  C07D403/10 ,  C07D401/14 ,  C07D401/10

CPC classification number: H10K85/654 ,  C07D239/26 ,  C09K11/06 ,  H10K85/626 ,  C07D213/16 ,  C07D405/10 ,  H10K85/615 ,  H10K85/6574 ,  C07D471/04 ,  H10K85/6572 ,  C07D409/14 ,  H10K85/6576 ,  C07D405/04 ,  H10K85/624 ,  C07D409/10 ,  C07D413/10 ,  H10K85/657 ,  C07D417/10 ,  C07D403/10 ,  C07D401/14 ,  C07D401/10 ,  H10K59/879

Abstract: An object of the present invention is to provide a compound with a high refractive index at a wavelength in range of 450 nm to 750 nm in a capping layer to improve light extraction efficiency of an organic EL device. The present invention was achieved by focusing on the fact that a heterocyclic compound has excellent thin film stability and durability and is able improve the refractive index by adjusting the molecular structures, and planning molecule, and an organic EL device having excellent luminous efficiency was obtained by using this compound as a material for constituting a capping layer.