专利检索 cpc:"C07C233/25" 第 1 页

1.

发明授权
Biaryl kinase inhibitors 有权

公开(公告)号：US12065437B2

公开(公告)日：2024-08-20

申请号：US17192985

申请日：2021-03-05

申请人： BRISTOL-MYERS SQUIBB COMPANY

发明人： Guanglin Luo , Carolyn Diane Dzierba , John E. Macor

IPC分类号： C07D471/04 , A61K31/4427 , A61K31/50 , A61P25/28 , C07C233/25 , C07D213/30 , C07D213/34 , C07D213/57 , C07D213/61 , C07D213/64 , C07D213/73 , C07D213/74 , C07D213/75 , C07D213/80 , C07D215/14 , C07D237/08 , C07D239/26 , C07D309/18 , C07D309/22 , C07D401/04 , C07D401/14 , C07D413/10

CPC分类号： C07D471/04 , A61K31/4427 , A61K31/50 , A61P25/28 , C07C233/25 , C07D213/30 , C07D213/34 , C07D213/57 , C07D213/61 , C07D213/64 , C07D213/73 , C07D213/74 , C07D213/75 , C07D213/80 , C07D215/14 , C07D237/08 , C07D239/26 , C07D309/18 , C07D309/22 , C07D401/04 , C07D401/14 , C07D413/10

摘要： The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.

2.

发明公开
ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF 审中-公开

公开(公告)号：US20230337677A1

公开(公告)日：2023-10-26

申请号：US17635631

申请日：2020-08-28

申请人： University of Florida Research Foundation, Incorporated

发明人： Jeffrey R. Bloomquist , Quentin R. Coquerel , Gary M. Richoux , Maia Tsikolia , Liu Yang

IPC分类号： A01N47/20 , C07C311/08 , A01N53/00 , A01N43/647 , A01N37/16 , A01N37/22 , C07C69/017 , C07D209/48 , C07C233/25 , A01P17/00 , A01N43/18 , C07D213/74 , C07C69/747 , A01N43/82 , C07D271/12 , C07D213/75 , A01N25/18 , C07C233/91 , A01N37/10 , C07D213/76 , C07D335/02 , A01N43/40 , C07C271/64 , C07D249/18 , A01N43/38 , A01N41/10 , C07C233/43 , C07C271/28 , C07C233/15 , C07C255/29 , C07C233/05 , A01N37/26 , C07C233/44 , C07C233/66

CPC分类号： A01N47/20 , C07C311/08 , A01N53/00 , A01N43/647 , A01N37/16 , A01N37/22 , C07C69/017 , C07D209/48 , C07C233/25 , A01P17/00 , A01N43/18 , C07D213/74 , C07C69/747 , A01N43/82 , C07D271/12 , C07D213/75 , A01N25/18 , C07C233/91 , A01N37/10 , C07D213/76 , C07D335/02 , A01N43/40 , C07C271/64 , C07D249/18 , A01N43/38 , A01N41/10 , C07C233/43 , C07C271/28 , C07C233/15 , C07C255/29 , C07C233/05 , A01N37/26 , C07C233/44 , C07C233/66 , C07C2601/10 , C07C2601/02

摘要： The subject matter described herein is directed to compounds, synergistic compositions, and methods for repelling arthropods, such as insects. The compositions comprise aryl and pyridyl-type compounds. The compounds demonstrate strong vapor and topical repellency when applied alone and in synergistic compositions.

3.

发明公开
INHIBITORS OF YAP/TAZ-TEAD ONCOPROTEINS, SYNTHESIS AND USE THEREOF 审中-公开

公开(公告)号：US20230286904A1

公开(公告)日：2023-09-14

申请号：US18013431

申请日：2021-07-02

申请人： BRIDGENE BIOSCIENCES, INC.

发明人： Chao ZHANG , Michael J. BISHOP , Hang CHEN , Ping CAO

IPC分类号： C07C233/25 , A61K45/06 , C07C233/27 , C07C251/42 , C07D333/32 , C07D333/36 , C07D213/643 , C07D311/68 , C07D215/38 , C07D213/64 , C07D261/08 , C07D231/12 , C07D231/54 , C07D261/20 , C07D271/06 , C07D249/06 , C07D309/14 , C07D261/12 , C07D217/24 , C07D213/40 , C07D237/08 , C07D275/02 , C07D205/04 , C07C233/23

CPC分类号： C07C233/25 , A61K45/06 , C07C233/23 , C07C233/27 , C07C251/42 , C07D205/04 , C07D213/40 , C07D213/64 , C07D213/643 , C07D215/38 , C07D217/24 , C07D231/12 , C07D231/54 , C07D237/08 , C07D249/06 , C07D261/08 , C07D261/12 , C07D261/20 , C07D271/06 , C07D275/02 , C07D309/14 , C07D311/68 , C07D333/32 , C07D333/36 , C07C2602/08 , C07C2602/10 , C07C2602/50

摘要： Disclosed herein are synthesis and use of covalent inhibitors selective for Transcriptional Enhancer Factor TEF-1 (TEAD1), which can be used for treatment of cancers such as glioblastoma, gastric cancer, colorectal cancer, pancreatic ductal adenocarcinoma (PDAC), and malignant pleural mesothelioma (MPM). Further disclosed herein are pharmaceutical compositions including the TEAD1 inhibitor and methods of treating cancers using the same.

4.

发明申请
PROCESS FOR PREPARING BIPHENYLAMINES FROM ANILIDES BY RUTHENIUM CATALYSIS 审中-公开

公开(公告)号：US20180362446A1

公开(公告)日：2018-12-20

申请号：US16113624

申请日：2018-08-27

申请人： BAYER CROPSCIENCE AKTIENGESELLSCHAFT

发明人： Thomas HIMMLER , Lars RODEFELD , Jonathan HUBRICH , Lutz ACKERMANN

IPC分类号： C07C231/12 , C07C233/15 , C07C233/25 , C07C233/29 , C07C233/66 , C07C233/75

CPC分类号： C07C231/12 , C07C233/15 , C07C233/25 , C07C233/75 , C07C233/66 , C07C233/29

摘要： The present invention relates to a novel process for preparing substituted biphenylamides of the general formula (V) characterized in that anilides of the formula (II) in a solvent other than tetrahydrofuran, are reacted with an organoboron compound of the formula (III) in the presence of a catalyst system consisting of a ruthenium catalyst, an activator, an oxidizing agent and a metal triflate.

5.

发明申请
BIARYL KINASE INHIBITORS 审中-公开

公开(公告)号：US20180134704A1

公开(公告)日：2018-05-17

申请号：US15865848

申请日：2018-01-09

申请人： BRISTOL-MYERS SQUIBB COMPANY

发明人： Guanglin Luo , Ling Chen , Carolyn Diane Dzierba , Jonathan L. Ditta , John E. Macor , Joanne J. Bronson

IPC分类号： C07D471/04 , C07D413/10 , A61K31/50 , C07D401/04 , C07D309/22 , C07D239/26 , C07D237/08 , C07D215/14 , C07D213/80 , C07D213/75 , C07D213/73 , C07D213/64 , C07D213/61 , C07D213/57 , C07D213/34 , C07D213/30 , C07C233/25 , C07D401/14

CPC分类号： C07D471/04 , A61K31/4427 , A61K31/50 , A61P25/28 , C07C233/25 , C07D213/30 , C07D213/34 , C07D213/57 , C07D213/61 , C07D213/64 , C07D213/73 , C07D213/74 , C07D213/75 , C07D213/80 , C07D215/14 , C07D237/08 , C07D239/26 , C07D309/18 , C07D309/22 , C07D401/04 , C07D401/14 , C07D413/10

摘要： The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.

6.

发明申请
METABOLITES OF (1R-TRANS)-N-[[2-(2,3-DIHYDRO-4-BENZOFURANYL)CYCLOPROPYL]METHYL]PROPANAMIDE 审中-公开

公开(公告)号：US20180099924A1

公开(公告)日：2018-04-12

申请号：US15836099

申请日：2017-12-08

申请人： Vanda Pharmaceuticals, Inc.

发明人： Marlene Michelle Dressman , Deepak Phadke

IPC分类号： C07C231/12

CPC分类号： C07C231/12 , A61K31/133 , A61K31/165 , C07B2200/13 , C07C233/18 , C07C233/25 , C07C233/47 , C07C2601/02

摘要： Isolated metabolites of (1R-trans)-N-[[2-(2,3-dihydro-4-benzofuranyl)cyclopropyl]-methyl]propanamide, methods for their use, and compositions containing the metabolites.