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公开(公告)号：US20240350515A1
公开(公告)日：2024-10-24
申请号：US18682824
申请日：2022-08-11
Applicant: CHEMO RESEARCH, S.L.
Inventor： Enrico COLLI , Salustiano PÉREZ
IPC: A61K31/585 , A61K9/20
CPC classification number: A61K31/585 , A61K9/2009 , A61K9/2013 , A61K9/2018 , A61K9/2054
Abstract: The present invention relates to drospirenone for use in a method for treating endometriosis, endometriosis associated pelvic pain (EAPP) and/or dysmenorrhea, comprising administering drospirenone in a biphasic regimen. The present invention furthermore relates to the use of drospirenone administered in such a biphasic regimen as a contraceptive and for inducing amenorrhea, as well as to a pharmaceutical composition and a kit comprising drospirenone administered in such a biphasic regimen.
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公开(公告)号：US20240350405A1
公开(公告)日：2024-10-24
申请号：US18760150
申请日：2024-07-01
Applicant: Zeenar Enterprises Pty Ltd
Inventor： David KANNAR , Gregory Yu Foo Szto , Tomer Madmon
CPC classification number: A61K9/0056 , A61K9/006 , A61K9/2013 , A61K9/2027 , A61K9/2059
Abstract: An oral disintegrating tablet that forms liquid crystalline particles or liquid crystalline bulk phase upon disintegration. The oral disintegrating tablet is fast disintegrating following contact with saliva and/or the oral mucosa but also provides slowed delivery of the active ingredient to avoid the difficulties associated with the speed of delivery of an active ingredient through the oral mucosa.
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公开(公告)号：US20240342101A1
公开(公告)日：2024-10-17
申请号：US18748483
申请日：2024-06-20
Applicant: Cybin UK Ltd
Inventor： Peter RANDS , Tiffanie BENWAY , Zelah JOEL , Marie LAYZELL , Ellen JAMES
IPC: A61K9/48 , A61K9/00 , A61K9/20 , A61K9/50 , A61K31/4045 , C07B59/00 , C07D209/16
CPC classification number: A61K9/485 , A61K9/0053 , A61K9/2009 , A61K9/2013 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K9/4858 , A61K9/4866 , A61K9/5057 , A61K31/4045 , C07B59/002 , C07D209/16 , C07B2200/05
Abstract: The present invention relates to a solid dosage form comprising two or more compounds selected from N,N-dimethyltryptamine and its deuterated analogues and pharmaceutically acceptable salts thereof, and methods of treatment (e.g., of a psychiatric disorder or a neurological disorder) comprising administering the solid dosage form to a patient in need thereof.
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公开(公告)号：US20240335423A1
公开(公告)日：2024-10-10
申请号：US18676679
申请日：2024-05-29
Applicant: SYNACT PHARMA APS
Inventor： Thomas BOESEN , Thomas Engelbrecht Nordkild JONASSEN , Hayley Ann REECE , Natalie Louise KELK , Alice Jane TURNER , Ross MCLELLAN
IPC: A61K31/402 , A61K9/20 , A61K9/28 , A61K31/519 , C07D207/335
CPC classification number: A61K31/402 , A61K9/20 , A61K9/2009 , A61K9/2013 , A61K9/2027 , A61K9/2054 , A61K9/2846 , A61K31/519 , C07D207/335 , C07B2200/13
Abstract: The present disclosure relates to crystalline forms of N-{3-[1-(2-nitrophenyl)-1H-pyrrol-2-yl]-allylidene}-aminoguanidinium salts having high solubility. The disclosure also relates to use of said crystalline forms in medicine.
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公开(公告)号：US12109218B2
公开(公告)日：2024-10-08
申请号：US17548755
申请日：2021-12-13
Applicant: ARATANA THERAPEUTICS, INC.
Inventor： Lesley Rausch-Derra , Tamara Newbold , Gopinath Devaraj , Akemi Shiraishi
IPC: A61K31/64 , A61K9/00 , A61K9/20 , A61K31/437
CPC classification number: A61K31/64 , A61K9/0053 , A61K9/2009 , A61K9/2013 , A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K9/2059 , A61K31/437
Abstract: The present disclosure provides a method for treating pain or inflammation in a non-human animal in need thereof. The method comprises administering to a non-human animal a pharmaceutical composition comprising a therapeutically effective amount of grapiprant. Also provided herein are pharmaceutical compositions for treating pain or inflammation in a non-human animal in need thereof. The pharmaceutical compositions comprise a therapeutically effective amount of grapiprant and an excipient, including flavorants.
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公开(公告)号：US12109196B2
公开(公告)日：2024-10-08
申请号：US18443689
申请日：2024-02-16
Applicant: BioXcel Therapeutics, Inc.
Inventor： Vasukumar Kakumanu , David Christian Hanley , Frank Yocca , Chetan Dalpatbhai Lathia , Lavanya Rajachandran , Robert Risinger
IPC: A61K31/4174 , A61K9/00 , A61K9/06 , A61K9/20 , A61K9/70 , A61K47/10 , A61K47/26 , A61K47/34 , A61K47/38 , A61K47/44 , A61P25/18 , A61P25/20 , A61P25/36
CPC classification number: A61K31/4174 , A61K9/006 , A61K9/06 , A61K9/2013 , A61K9/2018 , A61K9/7007 , A61K9/7015 , A61K47/10 , A61K47/26 , A61K47/34 , A61K47/38 , A61K47/44 , A61P25/18 , A61P25/20 , A61P25/36
Abstract: Disclosed herein are methods of administering relatively high doses of dexmedetomidine or a pharmaceutically acceptable salt thereof to a human subject, without also inducing significant sedation. The disclosed methods are particularly suitable for the treatment of agitation, especially when associated with neurodegenerative and/or neuropsychiatric diseases such as schizophrenia, bipolar illness such as bipolar disorder or mania, dementia, depression, or delirium.
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公开(公告)号：US20240317687A1
公开(公告)日：2024-09-26
申请号：US18421849
申请日：2024-01-24
Applicant: Cytokinetics, Inc.
Inventor： Sheng CUI , Henry MORRISON , Karthik NAGAPUDI , Shawn D. WALKER , Charles BERNARD , Karl Bennett HANSEN , Neil Fred LANGILLE , Alan Martin ALLGEIER , Steven M. MENNEN , Jacqueline C.S. WOO , Bradley Paul MORGAN , Alex MUCI (Deceased)
IPC: C07D213/75 , A61K9/20 , A61K31/496 , A61K47/38
CPC classification number: C07D213/75 , A61K9/2013 , A61K9/2018 , A61K9/2054 , A61K31/496 , A61K47/38
Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.
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公开(公告)号：US20240315974A1
公开(公告)日：2024-09-26
申请号：US18736621
申请日：2024-06-07
Applicant: MATRIPHARM INTERNATIONAL INC.
Inventor： Tien Canh LE , Mircea-Alexandru MATEESCU
IPC: A61K9/20 , A61K31/192 , A61K31/405 , A61K31/616 , A61K45/06
CPC classification number: A61K9/2059 , A61K9/2009 , A61K9/2013 , A61K9/2018 , A61K9/2027 , A61K9/205 , A61K9/2054 , A61K31/192 , A61K31/405 , A61K31/616 , A61K45/06
Abstract: The present document describes a monolithic tablet dosage form for delivery of an active ingredient at two different release rates comprising a carboxyl polymer complexed with a multivalent cation and a disintegrating agent for a first initial fast release of the active ingredient, and a modulating agent for a second sustained release of the active ingredient. Also described are processes for preparing the carboxyl polymer complexed with a multivalent cation, and carboxyl polymer made from the process.
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公开(公告)号：US20240307498A1
公开(公告)日：2024-09-19
申请号：US18681207
申请日：2022-08-05
Applicant: ReBalance Health, Inc.
Inventor： Russell GLENN , Justin HAI
IPC: A61K38/25 , A61K9/20 , A61K31/704 , A61K31/706 , A61K31/714 , A61K47/18 , A61K47/26
CPC classification number: A61K38/25 , A61K9/2013 , A61K31/704 , A61K31/706 , A61K31/714 , A61K47/183 , A61K47/26
Abstract: Described herein are sermorelin peptide compositions formulated for high oral bioavailability and high rates of absorption for treatment in a variety of applications, such as treatment of low testosterone, diminished endurance and energy, deficient immune system, slow metabolism, deficient cognitive function, poor sleep health, and poor bone health.
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公开(公告)号：US20240307311A1
公开(公告)日：2024-09-19
申请号：US18577095
申请日：2022-07-07
Applicant: ROQUETTE FRERES
Inventor： Yuan-Siang LUI , Keat-Theng CHOW , Rajeev GOKHALE , Olaf HAEUSLER
IPC: A61K9/20 , A61K31/496 , A61K31/522 , B33Y70/00 , C08B31/04 , C08B31/12
CPC classification number: A61K9/2059 , A61K9/2013 , A61K9/2018 , A61K9/2095 , A61K31/496 , A61K31/522 , B33Y70/00 , C08B31/04 , C08B31/12
Abstract: The instant invention relates to a printable material for 3D printing comprising a hydrolyzed and functionalized starch compound. It also relates to a process for 3D printing using the same. It also relates to products, in particular solid dosage forms, obtained thereof by 3D printing.
