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公开(公告)号：US20230357152A1
公开(公告)日：2023-11-09
申请号：US18019501
申请日：2021-08-02
申请人： BASF SE
发明人： Andreas Koch , Marcus Fehr , Vanessa Tegge , Chandan Day , Manojkumar Poonoth , Sarang Kulkarni , Ronan Le Vezouet , Christian Harald Winter , Georg Christoph Rudolf , Rakesh Rath , Smrit Khanna , Ian Robert Craig , Wassilios Grammenos , Thomas Grote , Gerd Stammler , Tobias Mentzel , Egon Haden , Joachim Rheinheimer
IPC分类号： C07D275/02 , C07D277/28 , C07D217/18 , C07D401/04 , C07D237/08 , A01N43/40 , A01N43/80 , C07D231/12 , C07D213/70 , A01N43/78 , A01N43/54 , A01N43/60 , A01N43/58 , C07D213/53 , C07D261/08 , C07D239/34 , A01P3/00 , A01N43/56 , A01N43/44 , A01N43/50 , C07D241/12 , C07D239/26 , A01N43/42
CPC分类号： C07D213/53 , A01N43/40 , A01N43/42 , A01N43/44 , A01N43/50 , A01N43/54 , A01N43/56 , A01N43/58 , A01N43/60 , A01N43/78 , A01N43/80 , A01P3/00 , C07D213/70 , C07D217/18 , C07D231/12 , C07D237/08 , C07D239/26 , C07D239/34 , C07D241/12 , C07D261/08 , C07D275/02 , C07D277/28 , C07D401/04
摘要： The present invention relates to the use of strobilurin type compounds of formula I and the N-oxides and the salts thereof for combating phytopathogenic fungi containing an amino acid substitution F129L in the mitochondrial cytochrome b protein (also referred to as F129L mutation in the mitochondrial cytochrome b gene) conferring resistance to Qo inhibitors, and to methods for combating such fungi. The invention also relates to novel compounds, processes for preparing these compounds, to compositions comprising at least one such compound, and to seeds coated with at least one such compound.
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公开(公告)号：US11320430B2
公开(公告)日：2022-05-03
申请号：US16348996
申请日：2017-12-27
发明人： Hirokazu Kai , Kousuke Hiroki , Yuuichi Ueya
IPC分类号： G01N33/553 , C07D275/03 , C07D275/04 , C07D275/02
摘要： The present invention relates to a magnetic particle dispersion, and the magnetic particle dispersion includes a magnetic particle, an isothiazoline compound, and an aqueous medium.
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公开(公告)号：US11236055B2
公开(公告)日：2022-02-01
申请号：US16311723
申请日：2017-06-29
发明人： Chia-Yu Huang , Brian F. McGuinness , Dongchuan Shi , Steven G. Kultgen , Jeffrey J. Letourneau , James R. Beasley , Philip D. Stein , Andrew G. Cole
IPC分类号： C07D261/08 , A61P5/48 , A61P3/04 , C07D209/44 , C07D213/02 , C07D213/26 , C07D213/65 , C07D213/73 , C07D235/14 , C07D237/08 , C07D239/26 , C07D241/08 , C07D275/02 , C07D401/12 , C07D405/10 , C07D471/04 , C07D487/04 , A61P35/00
摘要： The present invention relates to sulfonamide compounds of formula (I) and formula (II), or a pharmaceutically acceptable salt thereof. The present sulfonamide compounds are useful non-systemic TGR5 agonists that can be used to treat diabetic diseases in human. The present invention provides a pharmaceutical composition containing sulfonamide compounds of formula (I) and formula (II) and a method of making as well as a method of using same in treating patients inflicted with metabolic disorders by administering same. The compounds of the present invention may be used in combination with additional anti-diabetic drugs.
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公开(公告)号：US11066357B2
公开(公告)日：2021-07-20
申请号：US16954464
申请日：2018-12-24
IPC分类号： A61K31/55 , C07C233/65 , C07C235/56 , C07C235/64 , C07C243/38 , C07C255/44 , C07D211/16 , C07D211/38 , C07D213/75 , C07D221/04 , C07D223/16 , C07D231/12 , C07D231/40 , C07D233/88 , C07D275/02 , C07D277/46 , C07D333/36 , C07D333/38 , C07D401/12
摘要： The present disclosure is concerned with benzoannulene compounds that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, chikungunya, Venezuelan equine encephalitis, dengue, influenza, and zika, using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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公开(公告)号：US20200058959A1
公开(公告)日：2020-02-20
申请号：US16534690
申请日：2019-08-07
发明人： Yusuke MORINO , Izaya OKAE , Nobuhiro INOUE , Kazumasa TAKESHI
IPC分类号： H01M10/0567 , H01M10/0569 , H01M10/0568 , H01M10/0525 , C07C317/08 , C07C317/12 , C07C317/10 , C07D275/06 , C07D275/02
摘要： A secondary battery includes a positive electrode, a negative electrode, and an electrolytic solution where (A) the electrolytic solution contains a solvent and an electrolyte salt, the solvent containing ethylene carbonate, (B) a content of the electrolyte salt is from 0.8 mol/kg to 2.0 mol/kg both inclusive, (C) a content of the ethylene carbonate in the solvent is from 10 wt % to 30 wt % both inclusive, (D) a ratio M2/M1 of a number M2 of moles of the ethylene carbonate to a number M1 of moles of the electrolyte salt is from 0.4 to 2.4 both inclusive, and (E) the electrolytic solution contains at least one of sulfone compounds.
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公开(公告)号：US10327446B2
公开(公告)日：2019-06-25
申请号：US14757414
申请日：2014-06-23
发明人： Pascal Bindschädler , Wolfgang Von Deyn , Karsten Körber , Deborah L. Culbertson , Koshi Gunjima , Franz Josef Braun
IPC分类号： A01N47/34 , A01N43/80 , C07D275/02 , A01N47/30
摘要： The present invention relates to naphthyl- or isoquinolinyl-substituted isothiazoline compounds of formula I wherein the variables are as defined in the claims and description. The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.
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公开(公告)号：US20190177271A1
公开(公告)日：2019-06-13
申请号：US16042271
申请日：2018-07-23
申请人： JAPAN TOBACCO INC.
发明人： Takahisa MOTOMURA , Hironobu NAGAMORI , Koichi SUZAWA , Hirotsugu ITO , Toru MORITA , Satoru KOBAYASHI , Hisashi SHINKAI
IPC分类号： C07D205/04 , C07F7/08 , C07D295/192 , C07D207/04 , C07D211/06 , C07D213/30 , C07D213/56 , C07D403/12 , C07D401/12 , C07D401/06 , C07D333/22 , C07D295/18 , C07D295/08 , C07D275/02 , C07D271/10 , C07D271/06 , C07D263/32 , C07D257/04 , C07D249/08 , C07D239/26 , C07D231/12 , C07C317/22 , C07C311/04 , C07C271/30 , C07C271/16 , C07C259/10 , C07C255/53 , C07C255/12 , C07C235/66 , C07C235/42 , C07C233/25 , C07C233/18 , C07C217/20 , C07C215/70 , C07C215/44 , C07C69/76 , C07C69/732 , C07C69/712 , C07C65/17 , C07C59/72 , C07C59/56 , C07C49/83 , C07C43/253 , C07C43/23 , C07C39/42 , C07C35/52 , A61K31/5375 , A61K31/4523 , A61K31/4453 , A61K31/4439 , A61K31/4409 , A61K31/4406 , A61K31/4402 , A61K31/44 , A61K31/435 , A61K31/425 , A61K31/4245 , A61K31/421 , A61K31/4196 , A61K31/4155 , A61K31/415 , A61K31/41 , A61K31/401 , A61K31/40 , A61K31/397 , A61K31/381 , A61K31/277 , A61K31/235 , A61K31/192 , A61K31/167 , A61K31/166 , A61K31/136 , A61K31/121 , A61K31/10 , A61K31/085 , A61K31/05 , A61K31/045
摘要： The present invention provides an agent for the prophylactic or treatment of diabetes, diabetic complications, insulin resistance syndrome, metabolic syndrome, hyperglycemia, dyslipidemia, atherosclerosis, cardiac failure, cardiomyopathy, myocardial ischemia, brain ischemia, cerebral apoplexy, pulmonary hypertension, hyperlactacidemia, mitochondrial disease, mitochondrial encephalomyopathy or cancer, namely, a PDHK inhibitor and the like. A compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof, or a solvate thereof: wherein each symbol is as defined in the specification.
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公开(公告)号：US20170247355A1
公开(公告)日：2017-08-31
申请号：US15402628
申请日：2017-01-10
发明人： Megan Foley , Bradley Tait , Matthew Cullen
IPC分类号： C07D403/06 , C07D207/337 , C07D401/06 , C07D295/185 , C07D263/32 , C07D275/02 , C07D333/22 , C07D249/06 , C07D207/333 , C07D231/12
摘要： The present invention is directed to compounds having the Formulae (Ia-Ie), (II), (IIIa-IIId), (IVa-IVc), (Va-Vb), (VIa-VIe), (VII), (VIIIa-VIIIc), and (IX), pharmaceutically acceptable salts, prodrugs and solvates thereof, compositions of any of thereof and methods for the treatment of a condition associated with a dysfunction in proteostasis comprising an effective amount of these compounds.
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9.发明申请公开(公告)号：US20170129851A1
公开(公告)日：2017-05-11
申请号：US15363610
申请日：2016-11-29
IPC分类号： C07C311/06 , C07D275/02
CPC分类号： C07C311/06 , C07C311/04 , C07C311/09 , C07C311/17 , C07C311/29 , C07C311/48 , C07C313/06 , C07D275/02 , C07D275/06
摘要： The present invention provides compounds and pharmaceutical compositions for treating neurological diseases such as multiple sclerosis.
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公开(公告)号：US09556166B2
公开(公告)日：2017-01-31
申请号：US13468757
申请日：2012-05-10
申请人： Megan Foley , Bradley Tait , Matthew Cullen
发明人： Megan Foley , Bradley Tait , Matthew Cullen
IPC分类号： C07D401/06 , C07D403/06 , C07D405/06 , C07D471/04 , C07D207/333 , C07D207/337 , C07D231/12 , C07D249/06 , C07D263/32 , C07D275/02 , C07D295/185 , C07D333/20
CPC分类号： C07D403/06 , C07D207/333 , C07D207/337 , C07D231/12 , C07D249/06 , C07D263/32 , C07D275/02 , C07D295/185 , C07D333/20 , C07D333/22 , C07D401/06 , C07D405/06 , C07D471/04
摘要： The present invention is directed to compounds having the Formulae (Ia-Ie), (II), (IIIa-IIId), (IVa-IVc), (Va-Vb), (VIa-VIe), (VII), (VIIIa-VIIIc), and (IX), pharmaceutically acceptable salts, prodrugs and solvates thereof, compositions of any of thereof and methods for the treatment of a condition associated with a dysfunction in proteostasis comprising an effective amount of these compounds.
摘要翻译： 本发明涉及具有式（Ia-Ie），（II），（IIIa-IIId），（IVa-IVc），（Va-Vb），（VIa-VIe），（VII） -VIIIc）和（IX），其药学上可接受的盐，前药和溶剂化物，其任何组合物以及用于治疗与蛋白酶抑制功能障碍相关的病症的方法，其包含有效量的这些化合物。
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