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314 条记录 (耗时 0.042 秒)

    IMPROVED METHOD OF CARBONYLATING AN EPOXIDE
    2.
    发明公开
    IMPROVED METHOD OF CARBONYLATING AN EPOXIDE 审中-公开

    公开(公告)号：US20240166615A1

    公开(公告)日：2024-05-23

    申请号：US18282915

    申请日：2022-04-04

    申请人： Novomer, Inc.

    发明人： Branden Cole ,  Jeff Uhrig

    IPC分类号： C07D305/12 ,  B01J31/16 ,  B01J31/18

    CPC分类号： C07D305/12 ,  B01J31/1616 ,  B01J31/183

    摘要： A continuous method of carbonylating an epoxide and/or lactone with carbon monoxide with improved catalyst efficiency and reactor productivity is comprised of reacting the epoxy and/or lactone in a solvent with carbon monoxide in the presence of a catalyst at a temperature of at least 80° C. and an amount of water that is at most about 150 ppm of the effluent from the reactor. The amount of water in any of the ingredients used in a method of the invention is desirably substantially below the aforementioned water concentration in the effluent from the reactor. Likewise, in a method of the invention, the amount of polyether byproduct is substantially absent. The methods may be performed without recycling of the catalyst.

    Acrylonitrile Derivatives from Epoxide and Carbon Monoxide Reagents
    3.
    发明申请
    Acrylonitrile Derivatives from Epoxide and Carbon Monoxide Reagents 审中-公开

    公开(公告)号：US20190002400A1

    公开(公告)日：2019-01-03

    申请号：US16023136

    申请日：2018-06-29

    申请人： Novomer, Inc.

    发明人： Sadesh H. Sookraj

    IPC分类号： C07C253/26 ,  C07C255/08 ,  C07C51/347 ,  C07D305/12 ,  C08L67/04

    CPC分类号： C07C253/26 ,  C07C51/09 ,  C07C51/347 ,  C07C255/08 ,  C07D305/12 ,  C08L67/04 ,  C07C57/04 ,  C07C57/08

    摘要： The present invention is directed to reactor systems and processes for producing acrylonitrile and acrylonitrile derivatives. In preferred embodiments of the present invention, the processes comprise the following steps: introducing an epoxide reagent and carbon monoxide reagent to at least one reaction vessel through at least one feed stream inlet; contacting the epoxide reagent and carbon monoxide reagent with a carbonylation catalyst to produce a beta-lactone intermediate; polymerizing the beta-lactone intermediate with an initiator in the presence of a metal cation to produce a polylactone product; heating the polylactone product under thermolysis conditions to produce an organic acid product; optionally esterifying the organic acid product to produce one or more ester products; and reacting the organic acid product and/or ester product with an ammonia reagent under ammoxidation conditions to produce an acrylonitrile product.

    Device and method for continuously preparing high-purity AKD without solvent
    8.
    发明授权
    Device and method for continuously preparing high-purity AKD without solvent 有权
    无溶剂连续制备高纯度AKD的装置和方法

    公开(公告)号：US09562027B2

    公开(公告)日：2017-02-07

    申请号：US14649703

    申请日：2013-03-12

    申请人： SUZHOU TIANMA SPECIALTY CHEMICALS CO., LTD.

    发明人： Baochi Sun ,  Anqi Tan

    IPC分类号： C07D305/08 ,  B01J19/18 ,  B01J19/00 ,  B01J19/20 ,  C07D305/12 ,  B01F7/04 ,  C07C45/89 ,  C07C49/88

    CPC分类号： C07D305/08 ,  B01F7/048 ,  B01J19/0013 ,  B01J19/0066 ,  B01J19/1806 ,  B01J19/1812 ,  B01J19/20 ,  B01J2219/00076 ,  B01J2219/00081 ,  B01J2219/00092 ,  B01J2219/00094 ,  C07C45/89 ,  C07C49/88 ,  C07D305/12

    摘要： Device and method for continuously preparing high-purity AKD without solvent includes a reactor making continuous mixing of raw materials. The process includes: the tertiary amine feeding into the reactor and the continuously feeding acyl chloride from three to ten line; under operating state, the motor rotates the internal cylinder in relation to external cylinder, forcing the fed materials to convey and stir in the conveying section of annular column passage, forcing the materials to shear and mix by movement of shearing and kneading blades. Arrangement of conveying and mixing sections along the axial direction of annular column passage, causes sufficient reaction of materials and controls the material temperature through internal and external heat exchange systems until the reaction products are discharged from outlet. The device and process disperse reaction heat and sufficient material mixture and complete reaction to control the reaction temperature, viscosity and decrease the generation of side reaction.

    摘要翻译： 用于连续制备无溶剂的高纯度AKD的装置和方法包括使原料连续混合的反应器。 该方法包括：将叔胺进料到反应器中，并将三氯化碳连续进料至十线; 在操作状态下，电机相对于外筒旋转内筒，迫使供料物料在环形柱通道的输送段中传送和搅拌，迫使材料通过剪切和捏合叶片的移动进行剪切和混合。 沿着环形柱通道的轴向布置输送和混合部分，引起材料的充分反应，并通过内部和外部热交换系统控制材料温度，直到反应产物从出口排出。 该装置和工艺分散反应热和充分的物料混合，完全反应，控制反应温度，粘度和减少副反应的产生。

    Beta-lactones as antibacterial agents
    9.
    发明授权
    Beta-lactones as antibacterial agents 有权
    β-内酯作为抗菌剂

    公开(公告)号：US09521845B2

    公开(公告)日：2016-12-20

    申请号：US14028147

    申请日：2013-09-16

    申请人： Stephan A. Sieber ,  Thomas Bottcher

    发明人： Stephan A. Sieber ,  Thomas Bottcher

    IPC分类号： A01N43/20 ,  C07D305/12 ,  C07D305/14 ,  A61K31/337

    CPC分类号： A01N43/20 ,  A61K31/337 ,  C07D305/12 ,  C07D305/14

    摘要： The present invention relates to specific beta-lactone compounds and compositions thereof for the treatment of infections, such as, e.g., infections with bacteria or infections with protozoa, in particular infections with Gram-positive and/or Gram-negative bacteria and of infectious diseases caused by or related to Gram-positive and/or Gram-negative bacteria, and to the modulation of virulence of Gram-positive and/or Gram-negative bacteria or of protozoa by specific beta-lactone compounds. The invention further relates to the use of the compounds or compositions for preventing or eliminating biofilms.

    摘要翻译： 本发明涉及特定的β-内酯化合物及其组合物，用于治疗感染，例如细菌感染或原生动物感染，特别是革兰氏阳性和/或革兰氏阴性细菌感染和感染性疾病 由革兰氏阳性和/或革兰氏阴性细菌引起或与革兰氏阴性细菌相关，以及通过特异性β-内酯化合物调节革兰氏阳性和/或革兰氏阴性细菌或原生动物的毒力。 本发明还涉及用于预防或消除生物膜的化合物或组合物的用途。