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    Method for producing indancarbaldehyde
    2.
    发明授权
    Method for producing indancarbaldehyde 有权

    公开(公告)号：US10737993B2

    公开(公告)日：2020-08-11

    申请号：US16605628

    申请日：2018-03-09

    申请人： MITSUBISHI GAS CHEMICAL COMPANY, INC.

    发明人： Tatsuya Utamura

    IPC分类号： C07C45/49 ,  C07C47/546

    摘要： The present invention provides a method for producing indancarbaldehyde, including a step of reacting indan with carbon monoxide in the presence of hydrogen fluoride and boron trifluoride to obtain a reaction liquid including indancarbaldehyde, wherein the indan includes an amine, and a content of the amine is less than 1000 ppm by mass.

    THERAPEUTIC DRUG FOR ADULT T-CELL LEUKEMIA
    4.
    发明申请
    THERAPEUTIC DRUG FOR ADULT T-CELL LEUKEMIA 有权
    用于成人T细胞淋巴瘤的治疗药物

    公开(公告)号：US20110172185A1

    公开(公告)日：2011-07-14

    申请号：US13120114

    申请日：2009-08-22

    申请人： Masanori Baba ,  Yuichi Hashimoto

    发明人： Masanori Baba ,  Yuichi Hashimoto

    IPC分类号： A61K31/12 ,  A61K31/166 ,  A61K31/11 ,  A61K31/695 ,  A61K31/352 ,  A61K31/095 ,  A61K31/135 ,  C07C49/83 ,  C07C325/02 ,  C07C233/65 ,  C07C47/546 ,  C07F7/08 ,  C07C225/18 ,  C07D311/92 ,  A61P35/02

    CPC分类号： C07C49/83 ,  A61K31/10 ,  A61K31/11 ,  A61K31/12 ,  A61K31/166 ,  A61K31/352 ,  A61K31/695

    摘要： An object is to provide a novel therapeutic drug for adult T-cell leukemia having an ATL cell specific antitumor effect. The therapeutic drug for adult T-cell leukemia according to the invention is characterized by containing a compound represented by the formula I or a prodrug thereof, wherein R1 is H, OH, an alkoxy group, an acyl group, or a thioacyl group, R2 is an acyl group, a thioacyl group, CONR7R8, or CSNR7R8 (R7 and R8 being each independently H, an alkyl group containing 1 to 3 carbon atoms, or a phenyl group), or R1 and R2 together may form a ring, X1 and X2 may be the same or different and are each —CR3R4—, —SiR3R4— or oxygen, and R3 and R4 may be the same or different and are each an alkyl group containing 1 to 6 carbon atoms.

    摘要翻译： 目的是提供一种具有ATL细胞特异性抗肿瘤作用的成人T细胞白血病的新型治疗药物。 根据本发明的成人T细胞白血病的治疗药物的特征在于含有式I化合物或其前体药物，其中R1是H，OH，烷氧基，酰基或硫代酰基，R2 是酰基，硫代酰基，CONR7R8或CSNR7R8（R7和R8各自独立地为H，含有1至3个碳原子的烷基或苯基），或者R1和R2一起可以形成环，X1和 X2可以相同或不同，各自为-CR 3 R 4 - ， - SiR 3 R 4 - 或氧，R 3和R 4可以相同或不同，并且各自为含有1至6个碳原子的烷基。

    Converting propylene in an oxygenate-contaminated propylene stream to non-polymerization derivative products
    6.
    发明申请
    Converting propylene in an oxygenate-contaminated propylene stream to non-polymerization derivative products 审中-公开
    将含氧化合物污染的丙烯流中的丙烯转化为非聚合衍生物产物

    公开(公告)号：US20050209469A1

    公开(公告)日：2005-09-22

    申请号：US10805983

    申请日：2004-03-22

    申请人： John Shutt ,  Jeffrey Brinen

    发明人： John Shutt ,  Jeffrey Brinen

    IPC分类号： C07C2/66 ,  C07C45/50 ,  C07C51/25 ,  C07C253/08 ,  C07C255/12 ,  C10G3/00 ,  C07D301/03 ,  C07C47/546 ,  C07C51/16

    CPC分类号： C07C51/252 ,  C07C2/66 ,  C07C45/50 ,  C07C253/00 ,  Y02P20/582 ,  Y02P30/20 ,  C07C15/085 ,  C07C57/04 ,  C07C255/16 ,  C07C47/02

    摘要： The invention provides for directing an oxygenate-contaminated propylene-containing stream derived from an oxygenate to olefin reaction system to a derivative non-polymerization reactor for conversion of the propylene to one or more derivative non-polymerization products. Exemplary derivative non-polymerization propylene conversion processes include: oxidation to form acrolein, oxidation to form acrylic acid, ammoxidation to form acrylonitrile, liquid phase oxidation to form acetone, liquid phase hydration to form isopropanol, hydroformylation to form n-butyraldehyde and its subsequent aldol/hydrogenation to form 2-ethylhexanol, direct or indirect oxidation to form propylene oxide, alkylation to form cumene in the presence of phosphoric acid/Kieselguhr or a zeolite and the subsequent selective hydroperoxidation of cumene to form acetone and phenol.

    摘要翻译： 本发明提供了将衍生自含氧化合物的含氧化合物污染的含丙烯的物流引导到烯烃反应体系到衍生的非聚合反应器，以将丙烯转化成一种或多种衍生的非聚合产物。 示例性的衍生非聚合丙烯转化方法包括：氧化形成丙烯醛，氧化形成丙烯酸，氨氧化形成丙烯腈，液相氧化形成丙酮，液相水合形成异丙醇，加氢甲酰化形成正丁醛及其随后的醛醇 /氢化形成2-乙基己醇，直接或间接氧化形成环氧丙烷，在磷酸/硅藻土或沸石存在下进行烷基化以形成异丙基苯，随后选择性地对异丙基苯进行氢过氧化，形成丙酮和苯酚。

    Method for production of fluorine-containing aromatic compounds
    7.
    发明授权
    Method for production of fluorine-containing aromatic compounds 失效
    含氟芳香族化合物的制造方法

    公开(公告)号：US6043397A

    公开(公告)日：2000-03-28

    申请号：US139422

    申请日：1998-08-25

    申请人： Seiichi Teshima ,  Yoshinobu Asako

    发明人： Seiichi Teshima ,  Yoshinobu Asako

    IPC分类号： C07B39/00 ,  C07C17/18 ,  C07C45/41 ,  C07C45/63 ,  C07C19/08 ,  C07C25/13 ,  C07C47/52 ,  C07C47/546

    CPC分类号： C07C45/41 ,  C07B39/00 ,  C07C17/18 ,  C07C45/63

    摘要： A method for the production of a fluorine-containing aromatic compound is provided which allows the relevant reaction to proceed in a standard reaction vessel such as, for example, a glass vessel at room temperature under an ambient pressure without requiring provision of such special devices as have been necessary heretofore or adoption of harsh reaction conditions. This method comprises causing an aromatic compound (A) having a cyclic skeletal part of 6 to 16 carbon atoms containing a plurality of --C(.dbd.O)X groups, wherein X stands for a hydrogen atom, a halogen atom, or an alkyl group of 1 to 10 carbon atoms, and having the remaining hydrogen atoms unsubstituted or partly or wholly substituted with at least one species of halogen atom to react with a compound (B) represented by the formula: ##STR1## wherein R.sup.1 and R.sup.2 independently stand for an alkyl group of 1 to 6 carbon atoms or a phenyl group.

    摘要翻译： 提供了一种制备含氟芳族化合物的方法，其允许相关反应在标准反应容器例如玻璃容器中在室温下在环境压力下进行，而不需要提供如 迄今为止还是采用了苛刻的反应条件。 该方法包括使具有6〜16个碳原子的环状骨架部分的芳香族化合物（A）含有多个-C（= O）X基团，其中X表示氢原子，卤素原子或烷基 具有1至10个碳原子，并且其余的氢原子未被取代或部分或全部被至少一种卤素原子取代，以与由下式表示的化合物（B）反应：其中R1和R2独立地表示烷基 1至6个碳原子或苯基。