公开(公告)号：US20210130286A1

公开(公告)日：2021-05-06

申请号：US16491594

申请日：2018-03-04

申请人： STUDIENGESELLSCHAFT KOHLE MBH

发明人： Zhong LIAN ,  Bill MORANDI ,  Benjamin N. BHAWAL ,  Peng YU ,  Tristan DELCAILLAU

IPC分类号： C07C319/14 ,  C07C321/28 ,  C07D319/06 ,  C07C323/20 ,  C07F7/18 ,  C07C323/09 ,  C07F7/08 ,  C07C323/36 ,  C07D277/74 ,  C07D213/70 ,  C07D241/18 ,  C07J31/00 ,  C07C321/22 ,  C07D417/06

摘要： The present invention refers to a process for a catalytic aryl transfer to rearrange the backbone of aromatic C—X bonds.

公开(公告)号：US20200155511A1

公开(公告)日：2020-05-21

申请号：US16709370

申请日：2019-12-10

申请人： NISSAN CHEMICAL CORPORATION

发明人： Takeshi MITA ,  Takamasa Kikuchi ,  Takashi Mizukoshi ,  Manabu Yaosaka ,  Mitsuaki Komoda ,  Shinji Takii

IPC分类号： A61K31/421 ,  A61K9/00 ,  C07D413/14 ,  C07D261/04 ,  C07D413/04 ,  C07F7/08 ,  C07D417/12 ,  C07D417/06 ,  C07D413/12 ,  C07D413/06 ,  C07D261/16 ,  C07C323/09 ,  C07C281/02 ,  C07C255/60 ,  C07C255/50 ,  C07C255/29 ,  C07C251/48 ,  C07C211/52 ,  C07C205/12 ,  C07C205/11 ,  C07C43/174 ,  A01N43/80 ,  C07C25/08 ,  C07C25/06 ,  C07C25/02 ,  C07C25/24 ,  C07C25/13

摘要： A substituted alkenylbenzene compound of formula (4): wherein X1 is selected from the group consisting of a halogen atom, —SF5, C1-C6haloalkyl, hydroxy C1-C6haloalkyl, C1-C6alkoxy C1-C6haloalkyl, C3-C8halocycloalkyl, C1-C6haloalkoxy, C1-C3haloalkoxy C1-C3haloalkoxy, C1-C6haloalkylthio, C1-C6haloalkylsulfinyl and C1-C6haloalkylsulfonyl; X3 is selected from the group consisting of a hydrogen atom, halogen atom, cyano, nitro, C1-C6alkyl, C1-C6haloalkyl, C1-C6alkoxy and C1-C6alkylthio; X4 is selected from the group consisting of a hydrogen atom, halogen atom, cyano, C1-C4alkyl, C1-C4alkoxy and C1-C4haloalkoxy; R3 is —C(R3a)(R3b)R3c, where R3a and R3b independently of each other are a halogen atom, or R3a and R3b together form 3- to 6-membered ring together with the carbon atom bonding them by forming a C2-C5haloalkylene chain, and R3c is selected from the group consisting of a hydrogen atom, halogen atom, C1-C5alkyl, C1-C5haloalkyl, C1-C4haloalkoxy and C1-C4haloalkylthio, with a proviso that in case where X1 is a fluorine atom, chlorine atom or trifluoromethyl, and both X2 and X3 are a hydrogen atom, in case where both X1 and X2 are fluorine atom and X3 is a hydrogen atom, and in case where both X1 and X2 are trifluoromethyl and X3 is a hydrogen atom, R3c is a hydrogen atom, chlorine atom, bromine atom, iodine atom, C1-C5alkyl, C1-C5haloalkyl, C1-C4haloalkoxy or C1-C4haloalkylthio.

公开(公告)号：US20190155152A1

公开(公告)日：2019-05-23

申请号：US15817864

申请日：2017-11-20

申请人： ROHM AND HAAS ELECTRONIC MATERIALS LLC

发明人： Emad Aqad ,  James W. Thackeray

IPC分类号： G03F7/004 ,  C07D333/76 ,  C07C309/12 ,  C07C65/05 ,  C07C25/02 ,  C07C323/09 ,  C07C323/03 ,  G03F7/038 ,  G03F7/039 ,  G03F7/16 ,  G03F7/20 ,  G03F7/26

摘要： A photoacid generator compound having formula (I): wherein, in formula (I), groups and variables are the same as described in the specification.

公开(公告)号：US10239831B2

公开(公告)日：2019-03-26

申请号：US15976480

申请日：2018-05-10

申请人： BAYER CROPSCIENCE AG

发明人： Thomas Himmler ,  Julia Johanna Hahn

IPC分类号： C07C273/04 ,  C07C319/06 ,  C07C323/35 ,  C07C319/22 ,  C07C319/24 ,  C07C323/09 ,  C07C323/34 ,  C07C323/37

摘要： The present invention relates to a novel method for preparing bis(3-aminophenyl) disulphides of the general formula (I) and 3-aminothiols of the general formula (II), where X,Y have the meanings stated in the description, which serve as intermediates for the preparation of phenyl sulphoxides having insecticidal, acaricidal and nematicidal activity.

公开(公告)号：US20190023649A1

公开(公告)日：2019-01-24

申请号：US16047559

申请日：2018-07-27

申请人： Bikam Pharmaceuticals, Inc.

发明人： David S. Garvey ,  Judd Berman ,  Tan Quach

IPC分类号： C07C211/52 ,  C07C255/54 ,  C07C255/59 ,  C07C211/46 ,  C07C49/813 ,  C07C49/237 ,  C07C43/225 ,  C07C43/215 ,  C07C33/50 ,  C07C237/30 ,  C07C323/09 ,  C07C217/84 ,  C07C211/45 ,  C07D317/66 ,  C07D317/64 ,  C07D317/46 ,  C07C255/58

摘要： Compounds and compositions are disclosed that are useful for treating ophthalmic conditions caused by or related to production of toxic visual cycle products that accumulate in the eye, such as dry adult macular degeneration, as well as conditions caused by or related to the misfolding of mutant opsin proteins and/or the mis-localization of opsin proteins. Compositions of these compounds alone or in combination with other therapeutic agents are also described, along with therapeutic methods of using such compounds and/or compositions. Methods of synthesizing such agents are also disclosed.

公开(公告)号：US10040749B2

公开(公告)日：2018-08-07

申请号：US14361445

申请日：2012-11-29

申请人： Bikam Pharmaceuticals, Inc.

发明人： David S. Garvey ,  Judd Berman ,  Tan Quach

IPC分类号： C07D317/70 ,  C07C211/52 ,  C07C255/54 ,  C07C255/58 ,  C07D317/46 ,  C07D317/64 ,  C07D317/66 ,  C07C211/45 ,  C07C217/84 ,  C07C323/09 ,  C07C237/30 ,  C07C33/50 ,  C07C43/215 ,  C07C43/225 ,  C07C49/237 ,  C07C49/813 ,  C07C211/46 ,  C07C255/59

摘要： Compounds and compositions are disclosed that are useful for treating ophthalmic conditions caused by or related to production of toxic visual cycle products that accumulate in the eye, such as dry adult macular degeneration, as well as conditions caused by or related to the misfolding of mutant opsin proteins and/or the mis-localization of opsin proteins. Compositions of these compounds alone or in combination with other therapeutic agents are also described, along with therapeutic methods of using such compounds and/or compositions. Methods of synthesizing such agents are also disclosed.

公开(公告)号：US20170226054A1

公开(公告)日：2017-08-10

申请号：US15515007

申请日：2015-10-28

申请人： LG CHEM, LTD.

发明人： Hyun Woog RYU ,  Sehee JUNG ,  Joong Jin HAN ,  Yong Jin JANG ,  Youngjea KIM ,  Esder KANG

IPC分类号： C07C323/09 ,  H01M8/1039 ,  B01J39/19 ,  H01M8/18 ,  C08G75/12 ,  C08G75/0245

摘要： The present specification relates to a fluorine-based compound for a brancher, a polymer using the same, a polymer electrolyte membrane using the same, a fuel cell using the same, and a redox flow battery including the same.

公开(公告)号：US20170210990A1

公开(公告)日：2017-07-27

申请号：US15326204

申请日：2015-06-19

申请人： Merck Patent GmbH

发明人： Kevin ADLEM ,  Owain Llyr PARRI ,  Rachel TUFFIN ,  Hassan ARASI ,  Benjamin SNOW

IPC分类号： C09K19/32 ,  C09K19/58 ,  C09K19/02 ,  C07C25/22 ,  C07C43/225 ,  C07C255/55 ,  C07D215/06 ,  C07C69/94 ,  C07C323/38 ,  C07C69/67 ,  C07C323/31 ,  C07C255/52 ,  C07C323/09 ,  C07C69/708 ,  C07D239/74 ,  C07D333/54 ,  C07D333/76 ,  C07D241/48 ,  C07D241/42 ,  C07C327/32 ,  C07D307/82 ,  C09K19/34

摘要： The invention relates to bimesogenic compounds of formula I wherein R11, R12, MG11, MG12, X11, X12 and Sp1 have the meaning given in claim 1, to the use of bimesogenic compounds of formula I in liquid crystal media and particular to flexoelectric liquid crystal devices comprising a liquid crystal medium according to the present invention.

公开(公告)号：US09376384B2

公开(公告)日：2016-06-28

申请号：US14825169

申请日：2015-08-13

申请人： UBE INDUSTRIES, LTD.

发明人： Norimichi Saito ,  Norio Shibata ,  Kohei Matsuzaki ,  Kenta Okuyama

IPC分类号： C07C323/09 ,  C07D209/10 ,  C07D333/18 ,  C07D209/48 ,  C07C309/06 ,  C07C309/30 ,  C07C381/00

CPC分类号： C07C323/09 ,  C07C309/06 ,  C07C309/30 ,  C07C381/00 ,  C07C2602/08 ,  C07D209/10 ,  C07D209/48 ,  C07D333/18

摘要： Provided is a compound that allows easy introduction of a pentafluorosulfanylaryl group into a compound of interest.A diaryliodonium salt is represented by the general formula (d) shown below: In this formula, k is 1 or 2, R1 is an alkyl group having 1 or 2 carbon atoms, m is an integer of 0 to 4, R2 is a straight or branched alkyl group having 1 to 4 carbon atoms, n is an integer of 0 to 5, and A− is a counter anion.

摘要翻译： 提供了容易将五氟硫烷基芳基引入到目的化合物中的化合物。 二芳基碘盐由以下通式（d）表示：在该式中，k为1或2，R1为具有1或2个碳原子的烷基，m为0至4的整数，R2为直链 或具有1〜4个碳原子的支链烷基，n为0〜5的整数，A-为抗衡阴离子。

公开(公告)号：US09079831B2

公开(公告)日：2015-07-14

申请号：US14243058

申请日：2014-04-02

申请人： DIPHARMA FRANCIS S.r.l.

发明人： Pietro Allegrini ,  Simone Mantegazza

IPC分类号： C07C213/00 ,  C07C315/02 ,  C07C317/14 ,  C07C317/36 ,  C07C323/09 ,  C07C319/18

CPC分类号： C07C315/02 ,  C07C317/14 ,  C07C317/36 ,  C07C319/18 ,  C07C323/09 ,  C07C319/14 ,  C07C315/04 ,  C07C315/06

摘要： Process for the preparation of known sulfonamides having antibacterial activity applicable on industrial scale, which allows their production in high yields and purity, comprising in particular the step of nucleophile aromatic substitution and oxidation in suitable conditions.

摘要翻译： 制备具有适用于工业规模的抗菌活性的已知磺酰胺的方法，其允许其以高产率和纯度生产，特别包括在合适条件下亲核芳香取代和氧化的步骤。