公开(公告)号：US20240025845A1

公开(公告)日：2024-01-25

申请号：US18025134

申请日：2021-09-07

申请人： KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY

发明人： Jong Seog AHN ,  Sung Kyun KO ,  Jae Hyuk JANG ,  Jun Pil JANG ,  Jae Kyung JUNG ,  Nam Doo KIM ,  Bo Yeon KIM ,  Joon Suk PARK

IPC分类号： C07C311/08 ,  C07C237/52 ,  C07D209/48 ,  C07D333/34 ,  C07D213/64 ,  A61P35/00 ,  C07C311/44 ,  C07C311/29 ,  C07C311/21 ,  C07D333/18 ,  C07D231/16 ,  C07D215/36 ,  C07D403/04 ,  C07C311/14 ,  C07D271/12 ,  C07D319/18 ,  C07C311/13

CPC分类号： C07C311/08 ,  C07C237/52 ,  C07D209/48 ,  C07D333/34 ,  C07D213/64 ,  A61P35/00 ,  C07C311/44 ,  C07C311/29 ,  C07C311/21 ,  C07D333/18 ,  C07D231/16 ,  C07D215/36 ,  C07D403/04 ,  C07C311/14 ,  C07D271/12 ,  C07D319/18 ,  C07C311/13 ,  C07C2601/02

摘要： Provided is a metastasis-inhibiting composition containing a methylsulfonamide-based derivative compound as an active ingredient. More specifically, the compounds inhibit the activity of chromosome segregation 1-like (CSE1L), and suppress intracellular nuclear transport to inhibit the movement and/or invasion of cancer cells, and thus effectively inhibit metastasis.

公开(公告)号：US10076116B2

公开(公告)日：2018-09-18

申请号：US15029220

申请日：2014-10-15

申请人： BAYER CROPSCIENCE AKTIENGESELLSCHAFT

发明人： Philippe Desbordes ,  Philippe Rinolfi ,  Tomoki Tsuchiya ,  Julie Geist ,  Lionel Nicolas

IPC分类号： A01N43/56 ,  C07D403/14 ,  C07D405/14 ,  C07D417/14 ,  A01N43/54 ,  A01N43/647 ,  A01N43/10 ,  A01N43/36 ,  C07D401/14 ,  C07D409/14 ,  A01N43/78 ,  C07D333/18 ,  C07D333/38

CPC分类号： A01N43/56 ,  A01N43/10 ,  A01N43/36 ,  A01N43/54 ,  A01N43/647 ,  A01N43/78 ,  C07D333/18 ,  C07D333/38 ,  C07D401/14 ,  C07D403/14 ,  C07D405/14 ,  C07D409/14 ,  C07D417/14

摘要： The present invention relates to fungicidal N-cycloalkyl-N-(biheterocyclylmethylene)carboxamide derivatives and their thiocarbonyl derivatives, their process of preparation and intermediate compounds for their preparation, their use as fungicides, particularly in the form of fungicidal compositions and methods for the control of phytopathogenic fungi of plants using these compounds or their compositions.

公开(公告)号：US10072023B2

公开(公告)日：2018-09-11

申请号：US14947230

申请日：2015-11-20

申请人： SWITCH MATERIALS, INC.

发明人： Neil Robin Branda ,  Jeremy Graham Finden ,  Simon James Gauthier ,  Ali Hayek ,  Kyle Andrew Hope-Ross ,  James Daniel Senior ,  Andreea Spantulescu ,  Serguei Sviridov

IPC分类号： C07D495/04 ,  C07D493/14 ,  C07D409/14 ,  C07D519/00 ,  C07D495/14 ,  C07D333/38 ,  C07F7/18 ,  C07F7/08 ,  C07D333/22 ,  C07D493/22 ,  C07D513/14 ,  C07D493/04 ,  C07D277/22 ,  C07D513/04 ,  C09K9/02 ,  G02B1/04 ,  C07D307/79 ,  G02B5/20 ,  C07D333/12 ,  G02B5/22 ,  G02B5/23 ,  C07D333/18

CPC分类号： C07D495/04 ,  C07D277/22 ,  C07D307/79 ,  C07D333/12 ,  C07D333/18 ,  C07D333/22 ,  C07D333/38 ,  C07D409/14 ,  C07D493/04 ,  C07D493/14 ,  C07D493/22 ,  C07D495/14 ,  C07D513/04 ,  C07D513/14 ,  C07D519/00 ,  C07F7/0814 ,  C07F7/1804 ,  C09K9/02 ,  C09K2211/1007 ,  C09K2211/1088 ,  C09K2211/1092 ,  G02B1/04 ,  G02B5/20 ,  G02B5/223 ,  G02B5/23 ,  C08L101/12

摘要： A compound according to Formula IA and IB, reversibly convertible under photochromic and electrochromic conditions between a ring-open isomer A and a ring-closed isomer B is provided. For substitutent groups, Z is N, O or S; each R1 is independently selected from the group consisting of H, or halo; each R2 is independently selected from the group consisting of H, halo, a polymer backbone, alkyl or aryl; or, when both R2 together form —CH═CH— and form part of a polymer backbone; each R3 is independently selected from the group consisting of H, halo, alkyl, alkoxy, thioalkyl or aryl; each R4 is aryl; and each R5 is independently selected from the group consisting of H, halo, alkyl, alkoxy, thioalkyl or aryl.

公开(公告)号：US20180244596A1

公开(公告)日：2018-08-30

申请号：US15558978

申请日：2016-03-18

申请人： BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVEDA

发明人： Wesley A. CHALIFOUX ,  Kyle C. SPROUL ,  Wenlong YANG

IPC分类号： C07C43/205 ,  C07C205/06 ,  C07C25/22 ,  C07C211/50 ,  C07F7/08 ,  C07C15/38 ,  C07C22/08 ,  C07D333/08 ,  C07C309/68 ,  C08G61/10 ,  C07C25/24 ,  C07C41/20 ,  C07C201/12 ,  C07C209/68 ,  C07C5/09 ,  C07C17/354 ,  C07C303/30

CPC分类号： C07C43/2055 ,  C07C5/09 ,  C07C13/28 ,  C07C15/38 ,  C07C17/354 ,  C07C22/08 ,  C07C25/22 ,  C07C25/24 ,  C07C41/20 ,  C07C43/21 ,  C07C201/12 ,  C07C205/06 ,  C07C209/68 ,  C07C211/50 ,  C07C303/30 ,  C07C309/68 ,  C07C2601/14 ,  C07C2603/50 ,  C07C2603/54 ,  C07D333/08 ,  C07D333/18 ,  C07F7/0805 ,  C08G61/10 ,  C08G2261/1414 ,  C08G2261/148 ,  C08G2261/228 ,  C08G2261/312

摘要： Disclosed herein are embodiments of aryl compounds and polymers thereof that are made using methods that do not require harsh conditions or expensive reagents. The methods disclosed herein utilize precursor compounds that can be polymerized to form polycyclic aromatic hydrocarbons and polymers, such as carbon-based polymers like nanostructures (e.g., graphene or graphene-like nanoribbons).

公开(公告)号：US10035760B2

公开(公告)日：2018-07-31

申请号：US15031352

申请日：2014-10-23

申请人： VIIV HEALTHCARE UK (NO. 5) LIMITED

发明人： Annapurna Pendri ,  Guo Li ,  John A. Bender ,  Zhong Yang ,  Alan Xiangdong Wang ,  Brett R. Beno ,  Robert A. Fridell ,  Makonen Belema ,  Nicholas A. Meanwell ,  Robert G. Gentles

IPC分类号： A61K31/36 ,  A61K31/357 ,  A61K31/64 ,  A61K31/17 ,  A61K31/18 ,  C07C275/28 ,  C07C275/26 ,  C07C275/18 ,  C07C275/24 ,  C07C275/22 ,  C07C311/62 ,  C07C311/59 ,  C07C311/58 ,  C07C311/56 ,  C07C311/55 ,  C07D317/66 ,  C07D317/62 ,  C07D205/04 ,  C07D209/08 ,  C07D209/10 ,  C07D213/56 ,  C07D215/08 ,  C07D231/12 ,  C07D249/08 ,  C07D261/08 ,  C07D265/36 ,  C07D271/06 ,  C07D277/82 ,  C07D307/38 ,  C07D317/46 ,  C07D333/18 ,  C07D333/28 ,  C07D333/54 ,  C07D401/04 ,  C07D405/12 ,  C07D407/12 ,  C07D409/12 ,  C07D491/08 ,  C07D495/04

CPC分类号： C07C311/58 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2602/08 ,  C07D205/04 ,  C07D209/08 ,  C07D209/10 ,  C07D213/56 ,  C07D215/08 ,  C07D231/12 ,  C07D249/08 ,  C07D261/08 ,  C07D265/36 ,  C07D271/06 ,  C07D277/82 ,  C07D307/38 ,  C07D317/46 ,  C07D317/66 ,  C07D333/18 ,  C07D333/28 ,  C07D333/54 ,  C07D401/04 ,  C07D405/12 ,  C07D407/12 ,  C07D409/12 ,  C07D491/08 ,  C07D495/04

摘要： Compounds of Formula I with activity against HIV, including pharmaceutical compositions and methods for using these compounds in treating human immunodeficiency virus (HIV) infection, are set forth:

公开(公告)号：US10000462B2

公开(公告)日：2018-06-19

申请号：US14618597

申请日：2015-02-10

申请人： Samsung Electronics Co., Ltd.

发明人： Yeong Suk Choi ,  Kwang Hee Lee ,  Seon-Jeong Lim

IPC分类号： C07D333/50 ,  C07D333/24 ,  H01L51/00 ,  H01L27/30 ,  C07D333/18 ,  C07D409/14 ,  C07D495/04 ,  H01L51/42

CPC分类号： C07D333/24 ,  C07D333/18 ,  C07D409/14 ,  C07D495/04 ,  H01L27/307 ,  H01L51/0036 ,  H01L51/0043 ,  H01L51/0068 ,  H01L51/008 ,  H01L51/42

摘要： An optoelectronic material includes a first organic molecule and a second organic molecule crosslinked with each other, the first organic molecule and the second organic molecule having wavelength selectivity in a visible ray region.

公开(公告)号：US20170098786A1

公开(公告)日：2017-04-06

申请号：US15382745

申请日：2016-12-19

申请人： FUJIFILM CORPORATION

发明人： Tetsu KITAMURA ,  Masashi KOYANAGI ,  Yuta SHIGENOI

IPC分类号： H01L51/00 ,  C09D5/24

CPC分类号： H01L51/0074 ,  C07C43/162 ,  C07D307/77 ,  C07D333/18 ,  C07D493/06 ,  C07D495/04 ,  C07D495/14 ,  C07D495/22 ,  C07F7/00 ,  C08G2261/124 ,  C08G2261/1412 ,  C08G2261/3162 ,  C08G2261/3246 ,  C08G2261/344 ,  C08G2261/512 ,  C08G2261/92 ,  C08K5/01 ,  C08K5/45 ,  C09D5/24 ,  C09D11/106 ,  C09D11/36 ,  C09D11/52 ,  C09D165/00 ,  H01L29/786 ,  H01L51/0003 ,  H01L51/0004 ,  H01L51/0005 ,  H01L51/0054 ,  H01L51/0055 ,  H01L51/0068 ,  H01L51/0073 ,  H01L51/0094 ,  H01L51/0545 ,  H01L51/0558 ,  H01L51/0566 ,  C08L65/00

摘要： Objects of the present invention are to provide a composition for forming an organic semiconductor film that has excellent preservation stability and makes the obtained organic semiconductor element exhibit excellent driving stability in the atmosphere, to provide an organic semiconductor film using the composition for forming an organic semiconductor film, a method for manufacturing the organic semiconductor film, an organic semiconductor element, a method for manufacturing the organic semiconductor element, and to provide a novel organic semiconductor compound.A composition for forming an organic semiconductor film of the present invention contains a specific organic semiconductor having an alkoxyalkyl group as a component A and a solvent as a component B, in which a content of a non-halogen-based solvent is equal to or greater than 50% by mass with respect to a total content of the component B, and a content of the component A is equal to or greater than 0.7% by mass and less than 15% by mass.

公开(公告)号：US20160056389A1

公开(公告)日：2016-02-25

申请号：US14796383

申请日：2015-07-10

申请人： Lomox Limited

发明人： Gene Carl Koch

IPC分类号： H01L51/00 ,  C07D471/22 ,  C07D249/08 ,  C07C43/215 ,  C07D495/04 ,  C07D333/16 ,  C07C59/72 ,  C07D403/14 ,  C07D487/04

CPC分类号： H01L51/0069 ,  C07C43/215 ,  C07C59/72 ,  C07C69/54 ,  C07C2603/94 ,  C07D207/452 ,  C07D249/08 ,  C07D333/16 ,  C07D333/18 ,  C07D403/14 ,  C07D417/14 ,  C07D471/22 ,  C07D487/04 ,  C07D495/04 ,  C07D519/00 ,  C09K11/06 ,  C09K2211/1416 ,  C09K2211/1425 ,  C09K2211/1458 ,  C09K2211/1466 ,  C09K2211/1475 ,  H01L51/0037 ,  H01L51/0039 ,  H01L51/004 ,  H01L51/005 ,  H01L51/0058 ,  H01L51/0067 ,  H01L51/0068 ,  H01L51/0072 ,  H01L51/0074 ,  H01L51/0508 ,  H01L51/42 ,  H01L51/5012 ,  H01L51/5048 ,  H01L51/5293 ,  H01L2251/308 ,  Y02E10/549

摘要： OLED compounds of the general structure: B-S-A-S-B in which rod-like nuclei A comprise a condensed aromatic ring structure in turn comprising fluorene ring structures condensed with at least one additional fluorene ring structures wherein the fluorene ring systems comprised by the condensed aromatic structure are substituted at the 9-position, and in which the 9-positions of the fluorenes are not susceptible to oxidation.

摘要翻译： 一般结构的OLED化合物：BSASB，其中棒状核A包含稠合芳环结构，其又包含与至少一个另外的芴环结构缩合的芴环结构，其中由缩合芳族结构包含的芴环系统被取代 9位，芴的9位不易氧化。

公开(公告)号：US08975439B2

公开(公告)日：2015-03-10

申请号：US13690274

申请日：2012-11-30

申请人： Novartis AG

发明人： Ruben Alberto Tommasi ,  Michael David Shultz ,  Leslie Wighton McQuire ,  Pascal Rigollier ,  Olivier Rogel ,  Claus Ehrhardt

IPC分类号： C07C311/16 ,  A61K31/18 ,  C07D207/333 ,  C07D209/12 ,  C07C317/24 ,  C07D295/112 ,  A61K45/06 ,  C07D403/04 ,  C07D409/04 ,  A61K31/55 ,  C07D209/82 ,  C07D235/06 ,  C07D241/04 ,  C07C323/67 ,  C07D211/14 ,  C07D265/30 ,  C07D211/06 ,  C07D213/61 ,  C07D213/50 ,  C07D471/04 ,  C07D209/14 ,  C07D211/24 ,  C07D209/08 ,  C07D209/10 ,  C07D333/22 ,  A61K31/4402 ,  C07D401/04 ,  C07D295/116 ,  C07C311/46 ,  C07D223/04 ,  C07D333/18 ,  C07D413/04 ,  C07D221/16 ,  C07D295/192 ,  C07D207/20 ,  A61K31/451 ,  C07D209/80 ,  A61K31/437 ,  C07D213/40 ,  C07C311/29 ,  C07D487/04 ,  C07D231/56 ,  A61K31/495 ,  C07C311/39 ,  C07D235/08 ,  A61K31/5375

CPC分类号： C07D333/22 ,  A61K31/18 ,  A61K31/381 ,  A61K31/402 ,  A61K31/416 ,  A61K31/437 ,  A61K31/4402 ,  A61K31/4409 ,  A61K31/451 ,  A61K31/495 ,  A61K31/5375 ,  A61K31/55 ,  A61K45/06 ,  C07C311/16 ,  C07C311/29 ,  C07C311/39 ,  C07C311/46 ,  C07C317/24 ,  C07C323/67 ,  C07C2601/02 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2602/08 ,  C07D207/20 ,  C07D207/30 ,  C07D207/333 ,  C07D209/08 ,  C07D209/10 ,  C07D209/12 ,  C07D209/14 ,  C07D209/80 ,  C07D209/82 ,  C07D211/06 ,  C07D211/14 ,  C07D211/24 ,  C07D213/40 ,  C07D213/50 ,  C07D213/61 ,  C07D221/16 ,  C07D223/04 ,  C07D231/56 ,  C07D235/06 ,  C07D235/08 ,  C07D241/04 ,  C07D265/30 ,  C07D295/112 ,  C07D295/116 ,  C07D295/192 ,  C07D333/18 ,  C07D401/04 ,  C07D403/04 ,  C07D409/04 ,  C07D413/04 ,  C07D471/04 ,  C07D487/04

摘要： The present invention provides a compound of formula (I): said compound is inhibitor of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12, and/or MMP-13. Finally, the present invention also provides a pharmaceutical composition.

摘要翻译： 本发明提供式（I）化合物：所述化合物是MMP-2和/或MMP-8和/或MMP-9和/或MMP-12和/或MMP-13的抑制剂，因此 可以用于治疗以MMP-2，/或MMP-8和/或MMP-9，和/或MMP-12和/或MMP-13异常活性为特征的疾病或疾病。 因此，式（I）化合物可用于治疗由MMP-2和/或MMP-8和/或MMP-9和/或MMP-12和/或MMP- 13。 最后，本发明还提供药物组合物。

公开(公告)号：US08951831B2

公开(公告)日：2015-02-10

申请号：US14174431

申请日：2014-02-06

申请人： LG Chem, Ltd.

发明人： Jae Soon Bae ,  Dae Woong Lee ,  Dong Hoon Lee ,  Jae Chol Lee ,  Jun Gi Jang

IPC分类号： H01L51/00 ,  C07C15/24 ,  C07C15/28 ,  C07C15/38 ,  C07C15/40 ,  C07D251/02 ,  C07D401/04 ,  C07D403/04 ,  H01L51/05 ,  C07C13/567 ,  C07C13/72 ,  C07C15/20 ,  C07C15/58 ,  C07C211/54 ,  C07C211/58 ,  C07C211/61 ,  C07D235/18 ,  C07D333/18 ,  C09K11/06 ,  H05B33/14 ,  H01L51/42 ,  H01L51/50

CPC分类号： H01L51/0512 ,  C07C13/567 ,  C07C13/72 ,  C07C15/20 ,  C07C15/28 ,  C07C15/38 ,  C07C15/58 ,  C07C211/54 ,  C07C211/58 ,  C07C211/61 ,  C07C2603/18 ,  C07C2603/24 ,  C07C2603/50 ,  C07C2603/52 ,  C07C2603/94 ,  C07D235/18 ,  C07D333/18 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1011 ,  C09K2211/1014 ,  C09K2211/1029 ,  C09K2211/1033 ,  C09K2211/1037 ,  C09K2211/1044 ,  C09K2211/1059 ,  C09K2211/1092 ,  H01L51/0058 ,  H01L51/006 ,  H01L51/0068 ,  H01L51/0072 ,  H01L51/42 ,  H01L51/50 ,  H01L51/5012 ,  H01L51/5048 ,  H05B33/14 ,  Y02E10/549

摘要： The present invention relates to a new binaphthalene derivative, a preparation method thereof, and an organic electronic device using the same. The binaphthalene derivative according to the present invention can perform functions of hole injection and transportation, electron injection and transportation, or light emission in an organic electronic device including an organic light-emitting device, and the device according to the present invention has excellent characteristics in terms of efficiency, drive voltage and stability, and in particular excellent effects such as a low voltage and a long life time.

摘要翻译： 本发明涉及新的二萘衍生物，其制备方法和使用其的有机电子器件。 根据本发明的二萘衍生物可以在包括有机发光装置的有机电子器件中执行空穴注入和输送，电子注入和输送或发光的功能，并且根据本发明的装置具有优异的特性 效率条件，驱动电压和稳定性，特别是低电压，长寿命等优异的效果。