-
公开(公告)号：US12049452B2
公开(公告)日：2024-07-30
申请号：US18054272
申请日：2022-11-10
发明人： Joanne Holland , Alex Eberlin
IPC分类号： C07D237/32 , C07C65/03 , C07C65/05 , C07C65/10
CPC分类号： C07D237/32 , C07C65/03 , C07C65/05 , C07C65/10 , C07B2200/13
摘要： The invention relates to new 1:1 olaparib:hydroxybenzoic acid cocrystals. The invention also relates to new 2:1 olaparib:hydroxybenzoic acid cocrystals which may contain no water (anhydrous) or may optionally be hydrated. The invention also relates to pharmaceutical compositions containing an olaparib hydroxybenzoic acid cocrystal of the invention and a pharmaceutically acceptable carrier. The olaparib hydroxybenzoic acid cocrystals of the invention may be useful for the treatment of diseases that benefit from inhibition of poly (ADP-ribose) polymerase (PARP).
-
2.发明公开公开(公告)号：US20240101564A1
公开(公告)日：2024-03-28
申请号：US18517894
申请日：2023-11-22
发明人： Jing LI , Xiaosong YU , Xiaopeng CAI , Zhiwei WANG
IPC分类号： C07D487/04 , C07C53/128 , C07C57/15 , C07C59/255 , C07C65/05 , C07D213/80
CPC分类号： C07D487/04 , C07C53/128 , C07C57/15 , C07C59/255 , C07C65/05 , C07D213/80 , C07B2200/13
摘要： The present invention relates to salts of a PI3Kdelta inhibitor (referred to as “Compound A” hereinafter), preferably fumarate, and the crystalline forms thereof. The present invention also relates to the process of preparation and uses of the salts and crystalline forms of Compound A.
-
公开(公告)号：US11905246B2
公开(公告)日：2024-02-20
申请号：US17171127
申请日：2021-02-09
发明人： Mohamed Eddaoudi , Dongxu Xue , Ryan Luebke , Vincent Guillerm , Abdul Malik Puthan Peedikakkal , Karim Adil , Lukasz Weselinski
IPC分类号： C07D209/88 , B01J20/22 , B01J31/16 , C07C63/66 , C07C65/05 , C07C65/11 , B01J37/04 , B01J37/06 , C07D317/36
CPC分类号： C07D209/88 , B01J20/226 , B01J31/1691 , B01J37/04 , B01J37/06 , C07C63/66 , C07C65/05 , C07C65/11 , C07D317/36 , B01J2231/34 , B01J2531/0211 , B01J2531/36 , B01J2531/38 , B01J2531/845 , Y02C20/40
摘要： A molecular building block composition can include a metal ion component; and a ligand component including a core including at least one functional group associated with the metal ion component and the core.
-
公开(公告)号：US10807936B2
公开(公告)日：2020-10-20
申请号：US16711711
申请日：2019-12-12
发明人： Terri L. Boehm , Mangesh Bore , Jeffery N. Carroll , G. Davis Harris, Jr. , Matthew D. McReynolds , Justin R. Struble , Daniel P. Walker
IPC分类号： C07C51/363 , C07C67/035 , C07C51/377 , C07C69/88 , C07C51/367 , C07C67/317 , C07C67/307 , C07C51/29 , C07C69/92 , C07C69/84 , C07C65/05 , C07C65/21 , C07C47/565 , C07C47/56 , C07C47/575
摘要： The present disclosure relates, in general, to 5-halo-3,6-dichlorosalicylic acid compounds, 5-halo-3,6-dichlorosalicyaldehyde compounds, processes for preparing 5-halo-3,6-dichlorosalicylic acid compounds, processes for preparing 5-halo-3,6-dichlorosalicyaldehyde compounds, processes for preparing 3,6-dichlorosalicylic acid compounds, and processes that employ such compounds as intermediates in the preparation of the herbicide dicamba.
-
公开(公告)号：US10569252B2
公开(公告)日：2020-02-25
申请号：US15494449
申请日：2017-04-22
发明人： Banglin Chen , Feng Luo
摘要： A metal-organic framework (MOF) and uses thereof are provided herein, including an MOF comprising a repeat unit of the formula [Zn2(H2O)L.0.5H2O]n, wherein L is a ligand of the formula: The MOFs provided herein may be used in the separation of two or more gaseous molecules from each other. In some embodiments, the gaseous molecules are carbon dioxide and acetylene.
-
公开(公告)号：US20190248742A1
公开(公告)日：2019-08-15
申请号：US16396905
申请日：2019-04-29
发明人： Mohamed EDDAOUDI , Dongxu XUE , Ryan LUEBKE , Vincent GUILLERM , Abdul Malik Puthan PEEDIKAKKAL , Karim ADIL , Lukasz WESELINSKI
IPC分类号： C07D209/88 , B01J37/06 , B01J31/16 , C07C63/66 , C07C65/05 , C07C65/11 , B01J37/04 , C07D317/36 , B01J20/22
CPC分类号： C07D209/88 , B01J20/226 , B01J31/1691 , B01J37/04 , B01J37/06 , B01J2231/34 , B01J2531/0211 , B01J2531/36 , B01J2531/38 , B01J2531/845 , C07C63/66 , C07C65/05 , C07C65/11 , C07D317/36 , Y02C10/08
摘要： A molecular building block composition can include a metal ion component; and a ligand component including a core including at least one functional group associated with the metal ion component and the core.
-
公开(公告)号：US10357037B2
公开(公告)日：2019-07-23
申请号：US15708080
申请日：2017-09-18
IPC分类号： A01N55/02 , C07F15/04 , C07F1/10 , C07F3/06 , A01N59/16 , C07F1/00 , C07C51/41 , A01N25/34 , A01N37/40 , C07C65/05
摘要： The present invention relates to the synthesis of a variety of metal organic frameworks (MOFs) using low temperature and solvents which are considered to be not particularly harmful to the environment. There is also provided novel MOFs which may be made by the desired processes.
-
公开(公告)号：US20190155155A1
公开(公告)日：2019-05-23
申请号：US16251622
申请日：2019-01-18
发明人： Jun Hatakeyama , Masaki Ohashi
IPC分类号： G03F7/038 , C07C309/65 , G03F7/38 , G03F7/32 , G03F7/20 , C07C65/05 , C07C63/70 , C07C233/54 , C07C271/28 , C07C381/12 , C07D279/20 , C07D327/08 , C07D333/76 , G03F7/004 , G03F7/039 , C07C57/58 , C07C65/03 , C07C309/66 , G03F7/16
摘要： A resist composition comprising a base polymer and a sulfonium salt of iodized benzoic acid offers a high sensitivity and minimal LWR independent of whether it is of positive or negative tone.
-
9.发明申请公开(公告)号：US20170293223A1
公开(公告)日：2017-10-12
申请号：US15634941
申请日：2017-06-27
发明人： Takashi NAGAMINE , Kotaro ENDO , Hideto NITO
IPC分类号： G03F7/004 , C07C381/12 , G03F7/039 , G03F7/32 , G03F7/16 , G03F7/20 , G03F7/38 , C07C65/05 , G03F7/038
CPC分类号： G03F7/0045 , C07C63/08 , C07C65/05 , C07C65/10 , C07C321/28 , C07C381/12 , G03F7/0046 , G03F7/0382 , G03F7/0392 , G03F7/0397 , G03F7/162 , G03F7/168 , G03F7/2006 , G03F7/2041 , G03F7/325 , G03F7/38 , G03F7/40
摘要： A resist composition which generates acid upon exposure and exhibits changed solubility in a developing solution under action of acid, the resist composition including a base component (A) which exhibits changed solubility in a developing solution under action of acid, and a compound (D1) represented by general formula (d1), wherein Z− represents an anion having an aromatic ring containing a hydroxybenzoic acid skeleton, provided that at least one hydrogen atom of the aromatic ring has been substituted with a halogen atom; m represents an integer of 1 or more; and Mm+ represents an organic cation having a valency of m. Z−(Mm+)1,m (d1)
-
10.发明授权公开(公告)号：US09671690B2
公开(公告)日：2017-06-06
申请号：US15072036
申请日：2016-03-16
发明人： Takashi Nagamine , Daichi Takaki , Miki Shinomiya
IPC分类号： G03F7/004 , G03F7/039 , G03F7/20 , G03F7/30 , G03F7/32 , C07C309/04 , C07C309/19 , C07C309/25 , C07C309/29 , C07C309/30 , C07C381/12 , C07C311/04 , C07C309/07 , C07C309/06 , C07C65/05 , C07C53/21 , C07D307/00
CPC分类号： G03F7/0045 , C07C53/21 , C07C65/05 , C07C309/04 , C07C309/06 , C07C309/07 , C07C309/19 , C07C309/25 , C07C309/29 , C07C309/30 , C07C311/04 , C07C381/12 , C07C2602/42 , C07C2603/74 , C07D307/00 , G03F7/0046 , G03F7/0397 , G03F7/2041 , G03F7/30 , G03F7/322
摘要： A resist composition which generates an acid upon exposure and whose solubility in a developing solution changes under the action of an acid. The composition includes a base material component whose solubility in a developing solution changes under the action of an acid; an acid generator component which generates an acid upon exposure; and a photo-reactive quencher which contains a compound represented by the general formula shown below: in which Ra1 represents an alkyl group having 1 to 10 carbon atoms which may have a substituent; and Ra2 and Ra3 each independently represent an alkyl group having 1 to 10 carbon atoms which may have a substituent. X− represents a counter anion.
-
-
-
-
-
-
-
-
-
搜索结果
214 条记录 (耗时 0.028 秒)
