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公开(公告)号:US11752183B2
公开(公告)日:2023-09-12
申请号:US16499990
申请日:2018-04-03
申请人: TCI CO., LTD
发明人: Yung-Hsiang Lin , I-Hui Chen , Kai-Wen Kan , Fu Chen Liu , Ciao-Ting Chen
IPC分类号: A61K36/185 , A23L33/105 , A61K9/00 , A61K9/08 , A61K9/48 , A61P3/04 , A61K31/01 , A61K31/015 , A61K36/21 , A61K36/258 , A61K36/31 , A61K36/45 , A61K36/48 , A61K36/53 , A61K36/67 , A61K36/73 , A61K36/74 , A61K36/752 , A61K36/815 , A61K36/82 , A61K36/87 , A61K36/886 , A61K36/8962 , A61K36/9066 , A61K8/9789 , A61P17/16 , A61Q19/00 , A23F3/16 , A61K8/97 , A61Q17/04 , A61P19/04 , A61Q19/08
CPC分类号: A61K36/185 , A23F3/163 , A23L33/105 , A61K8/97 , A61K8/9789 , A61K9/0056 , A61K9/0095 , A61K9/08 , A61K9/48 , A61K31/01 , A61K31/015 , A61K36/21 , A61K36/258 , A61K36/31 , A61K36/45 , A61K36/48 , A61K36/53 , A61K36/67 , A61K36/73 , A61K36/74 , A61K36/752 , A61K36/815 , A61K36/82 , A61K36/87 , A61K36/886 , A61K36/8962 , A61K36/9066 , A61P3/04 , A61P17/16 , A61P19/04 , A61Q17/04 , A61Q19/007 , A61Q19/08 , A23V2002/00
摘要: Provided is a plant extract-containing composition for reducing skin damage caused by ultraviolet radiation. The composition includes a combination of extracts of spinach, black tea, green tea, Pu-erh tea, Four Seasons Spring tea, red wine, blueberry, grape seeds, citrus, or green coffee beans.
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公开(公告)号:US20220233547A1
公开(公告)日:2022-07-28
申请号:US17615122
申请日:2020-06-02
发明人: Hirokazu KAWAGISHI , Hisae AOSHIMA
摘要: A cell activator of an animal cell that includes 3H-imidazo[4,5-d][1,2,3]triazine-4,6(5H,7H)-dione.
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公开(公告)号:US11382878B2
公开(公告)日:2022-07-12
申请号:US16618161
申请日:2017-05-31
申请人: Johnpro Biotech Inc.
发明人: Kwan-Hwa Chi , Yu-Shan Wang , Hsin-Chien Chiang , Kai-Chung Cheng
摘要: Disclosed herein are compositions and methods for the treatment of conditions induced by chronic inflammation. According to some embodiments, the compositions and methods involve the use of metformin and sodium butyrate in the treatment of conditions induced by chronic inflammation.
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公开(公告)号:US11337899B2
公开(公告)日:2022-05-24
申请号:US16331933
申请日:2017-10-06
申请人: Noxell Corporation
发明人: Ken Nguyen , Johanne Richard
IPC分类号: A61K8/04 , A61K8/25 , A61K8/73 , A61Q1/02 , A61K8/81 , A61K8/26 , A61K8/37 , A61P17/16 , A61Q17/04
摘要: Provided herein is a cosmetic composition comprising gellant technology combined with at least two different gelling agents; neutralizing agent; colorant; and water.
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公开(公告)号:US11236074B2
公开(公告)日:2022-02-01
申请号:US15562725
申请日:2016-04-06
发明人: Todd Ridky , Christopher Natale
IPC分类号: A61K8/49 , C07D405/04 , C07D491/048 , A61P17/06 , A61P17/18 , A61P17/14 , A61P17/00 , A61P17/16 , C07D221/16 , A61Q19/02 , A61Q17/04
摘要: The present invention includes compounds, compositions comprising the same, and methods using the compounds and/or compositions therein, for modulating skin pigmentation in a mammalian subject. In certain embodiments, the compounds of the invention treat or prevent skin disorders or diseases associated with hyperpigmentation in the subject. In other embodiments, the compounds of the invention act as antagonist to the non-canonical sex steroid hormone receptor GPRE1 and do not bind to a canonical nuclear estrogen receptor (ER). In yet other embodiments, the compounds of the invention comprise acts as agonists to the non-canonical sex steroid hormone receptor PAQR7 and do not bind to a canonical nuclear progesterone receptor (PR).
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公开(公告)号:US11179414B2
公开(公告)日:2021-11-23
申请号:US16375986
申请日:2019-04-05
申请人: LAIMU CORPORATION
发明人: Sachio Wakayama
IPC分类号: A61K31/728 , C08B37/08 , C07D307/62 , A61K31/341 , C12N9/50 , A61P17/02 , A61K38/00 , A61K9/00 , A61K31/38 , A61P17/16
摘要: Disclosed is a method for producing a protease degradation composition by degrading a composition containing a hyaluronic acid and a protein with a protease, in the presence of an ascorbic acid, an ascorbate or a salt thereof. The composition produced according to the method has a high fibroblast proliferation promoting effect and a high collagen production promoting effect.
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公开(公告)号:US20210236574A1
公开(公告)日:2021-08-05
申请号:US17239042
申请日:2021-04-23
IPC分类号: A61K36/185 , A61K8/49 , A61Q17/04 , A61Q19/08 , A61Q19/06 , A61Q17/00 , A61Q19/00 , A61K8/9789 , A61P17/16 , A61P29/00 , A61K8/368 , A61K31/192 , A61K31/353
摘要: The invention relates to a polyphenolic extract of passion flower seeds, in particular Passiflora incarnata or Passiflora edulis seeds, comprising at least 30 percent by weight polyphenols, expressed as gallic acid equivalent, relative to the weight of the dry extract. The invention also relates to a method for preparing an extract of said type, a composition containing same, and the cosmetic, dermatological or therapeutic use thereof.
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公开(公告)号:US20210137888A1
公开(公告)日:2021-05-13
申请号:US15930847
申请日:2020-05-13
IPC分类号: A61K31/4164 , A61K9/00 , A61K31/569 , A61K36/185 , A61K31/045 , A61K31/23 , A61K36/47 , A61K36/899 , A61K36/22 , A61K36/54 , A61K36/758 , A61K31/35 , A61P17/16 , A61P11/02
摘要: A combination product comprising a nasal spray dispenser containing a formulation for nasal administration, and a balm holder element containing a skin-care balm, attached to a bottom of the nasal spray dispenser.
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公开(公告)号:US20210106510A1
公开(公告)日:2021-04-15
申请号:US17046636
申请日:2019-04-10
IPC分类号: A61K8/37 , A61K8/9789 , A61Q19/00 , A61K36/28 , A61K31/216 , A61P17/16
摘要: Disclosed is a composition including, per 100% of its mass: a) 60.0% to 75.0% by mass of an organic solvent (OS1) chosen from 1,2-propanediol, 1,3-propanediol, 1,4-butanediol, 1,3-butanediol, 1,2-butanediol, 2-methyl-2,4-pentanediol, 1,6-hexanediol, 1,8-octanediol, or a mixture of these compounds; b) 0.1% to 2.0% by mass of a composition (ES) including an amount by mass x1, expressed as mass equivalent of 1-O-(2-caffeoyl)maloyl-3,5-di-O-caffeoylquinic acid, of greater than or equal to 200 mg/g of a compound of general formula (I): in which Q1, Q2, Q3, Q4 and Q5 represent, independently of each other, a hydroxyl radical or a salt thereof or a radical chosen from caffeoyl, maloyl, caffeoyl maloyl and maloyl caffeoyl radicals, it being understood that at least one of these radicals Q1, Q2, Q3, Q4 and Q5 represents neither the —OH radical nor a salt thereof; and c) 20.0% to 35.0% by mass of water. Related treatments are also disclosed.
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公开(公告)号:US10946075B1
公开(公告)日:2021-03-16
申请号:US15896094
申请日:2018-02-14
IPC分类号: A61K38/48 , A61K33/42 , A61K33/08 , A61K36/82 , A61K36/05 , A61K9/48 , A61K36/55 , A61K31/353 , A61K36/889 , A61K36/736 , A61K31/519 , A61K35/02 , A61K38/44 , A61K31/122 , A61K36/16 , A61K36/53 , A61K31/197 , A61K31/375 , A61K31/385 , A61K31/015 , A61K33/26 , A61K33/34 , A61K31/404 , A61K31/765 , A61K9/70 , A61K36/738 , A61K36/68 , A61K31/734 , A61K33/30 , A61K31/191 , A61K31/593 , A61K33/10 , A61K31/714 , A61K36/185 , A61K9/00 , A61K31/198 , A61K31/465 , A61K31/194 , A61K31/295 , A61K33/18 , A61K31/5685 , A61K33/44 , A61P17/06 , A61K33/06 , A61P17/16
摘要: Radioprotection, Radiomitigation and Radiorecovery: Timed use of more widely available antiradiation agents in a kit for subjects affected by ionizing radiation, radiomimetic exposure and radiocontamination. The method in the form of strategically timed preemptive and postirradiation compositions; radioprotection, radiomitigation and radiorecovery formulations are comprised of various available anticorporation, antioxidant, decorporation, multi-mechanistic, pro-survival, pro-hematopoietic, anti-fibrotic and other novel ingredients in synergistic mixtures to be used in critically-timed manners. Radioprotection, radiomitigation and radiorecovery of a mammal prior to, during, just after or well-after exposure to ionizing radiation energy—alpha, beta, neutron, gamma, X-ray and damaging radiofrequency radiation—for long or short periods of time, and exposure to or contamination by radioactive elements or compounds such as radioiodine, radiostrontium, radiophosphorus, radiocobalt, radiocadmium, radiopollonium, radioradium, radiocesium, radiouranium, radioamericium, radiopollonium, radiocerium, radioindium, and the like. Radiomimeticprotective method for mucosal exposure is also described.
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