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公开(公告)号:US11278582B2
公开(公告)日:2022-03-22
申请号:US16499666
申请日:2018-04-03
Applicant: TCI CO., LTD.
Inventor: Yung-Hsiang Lin , I-Hui Chen , Kai-Wen Kan , Fu Chen Liu , Ciao-Ting Chen
IPC: A61K36/00 , A61K36/185 , A23L33/105 , A61K9/00 , A61K9/08 , A61K9/48 , A61P3/04 , A61K31/01 , A61K31/015 , A61K36/21 , A61K36/258 , A61K36/31 , A61K36/45 , A61K36/48 , A61K36/53 , A61K36/67 , A61K36/73 , A61K36/74 , A61K36/752 , A61K36/815 , A61K36/82 , A61K36/87 , A61K36/886 , A61K36/8962 , A61K36/9066 , A61K8/9789 , A61P17/16 , A61Q19/00 , A23F3/16 , A61K8/97 , A61Q17/04 , A61P19/04 , A61Q19/08
Abstract: Provided is a composition for reducing the fat content of fat-producing cells and applications thereof. The composition includes plant extracts such as a blueberry extract and a black tea extract.
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公开(公告)号:US10918681B2
公开(公告)日:2021-02-16
申请号:US16498737
申请日:2018-04-03
Applicant: TCI CO., LTD.
Inventor: Yung-Hsiang Lin , I-Hui Chen , Kai-Wen Kan , Fu Chen Liu , Ciao-Ting Chen
IPC: A61K36/00 , A61K36/185 , A23L33/105 , A61K9/00 , A61K9/08 , A61K9/48 , A61P3/04 , A61K31/01 , A61K31/015 , A61K36/21 , A61K36/258 , A61K36/31 , A61K36/45 , A61K36/48 , A61K36/53 , A61K36/67 , A61K36/73 , A61K36/74 , A61K36/752 , A61K36/815 , A61K36/82 , A61K36/87 , A61K36/886 , A61K36/8962 , A61K36/9066 , A61K8/9789 , A61P17/16 , A61Q19/00 , A23F3/16 , A61K8/97 , A61Q17/04 , A61P19/04 , A61Q19/08
Abstract: The present disclosure provides a method for regulating expression of PDGFC, FGF2, IGF1R, PTGIS, NOS3, EDN1, PLAT, PROC, VWF, F3, SERPINE1, IL-8, ICAM1, VCAM1, and CASP8 genes, including administering to a subject in need thereof a composition including an effective amount of a plant extract, wherein the plant extract includes at least one combination selected from the group consisting of a grape seed extract and a Four seasons spring tea extract, a black tea extract and a spinach extract, the grape seed extract and the spinach extract, the grape seed extract and a green coffee bean extract, a red wine extract and a Pu-erh tea extract, and the grape seed extract and the Pu-erh tea extract.
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公开(公告)号:US11806317B2
公开(公告)日:2023-11-07
申请号:US16499350
申请日:2018-04-03
Applicant: TCI CO., LTD
Inventor: Yung-Hsiang Lin , I-Hui Chen , Kai-Wen Kan , Fu Chen Liu , Ciao-Ting Chen
IPC: A61K36/185 , A23L33/105 , A61K9/00 , A61K9/08 , A61K9/48 , A61P3/04 , A61K31/01 , A61K31/015 , A61K36/21 , A61K36/258 , A61K36/31 , A61K36/45 , A61K36/48 , A61K36/53 , A61K36/67 , A61K36/73 , A61K36/74 , A61K36/752 , A61K36/815 , A61K36/82 , A61K36/87 , A61K36/886 , A61K36/8962 , A61K36/9066 , A61K8/9789 , A61P17/16 , A61Q19/00 , A23F3/16 , A61K8/97 , A61Q17/04 , A61P19/04 , A61Q19/08
CPC classification number: A61K36/185 , A23F3/163 , A23L33/105 , A61K8/97 , A61K8/9789 , A61K9/0056 , A61K9/0095 , A61K9/08 , A61K9/48 , A61K31/01 , A61K31/015 , A61K36/21 , A61K36/258 , A61K36/31 , A61K36/45 , A61K36/48 , A61K36/53 , A61K36/67 , A61K36/73 , A61K36/74 , A61K36/752 , A61K36/815 , A61K36/82 , A61K36/87 , A61K36/886 , A61K36/8962 , A61K36/9066 , A61P3/04 , A61P17/16 , A61P19/04 , A61Q17/04 , A61Q19/007 , A61Q19/08 , A23V2002/00
Abstract: A composition comprising a grape seed extract and a black tea extract. The composition can increase testosterone secretion more effectively than a single component, and can be used for preparing pharmaceutical compositions, foods, health foods, dietary supplements or drinks used for promoting testosterone secretion.
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公开(公告)号:US10675319B2
公开(公告)日:2020-06-09
申请号:US16169608
申请日:2018-10-24
Applicant: TCI CO., LTD
Inventor: Yung-Hsiang Lin , I-Hui Chen
IPC: A61K36/42 , A61P3/10 , A23L33/105 , A61P35/00
Abstract: A method for at least one of adjusting the biological clock, improving sleep quality, and facilitating sleep is provided, wherein the method comprises administering to the subject an effective amount of a Momordica charantia extract, wherein the extract is obtained by extracting a fruit of Momordica charantia with water.
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公开(公告)号:US10149871B2
公开(公告)日:2018-12-11
申请号:US15629076
申请日:2017-06-21
Applicant: TCI CO., LTD
Inventor: Yung-Hsiang Lin , I-Hui Chen , Hui-Hsin Shih , Chi-Ying Lee
IPC: A61K39/09 , A61K35/744 , A61K9/00
Abstract: A method for at least one of preventing osteoporosis, treating osteoporosis, delaying bone loss, increasing bone density, and strengthening bones is provided, wherein the method comprises administering to a subject in need an effective amount of Streptococcus thermophilus TCI633 strain and/or its metabolites. The Streptococcus thermophilus TCI633 strain was deposited at German Collection of Microorganisms and Cell Cultures (Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH, DSMZ) under the accession number DSM 28121.
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公开(公告)号:US10918682B2
公开(公告)日:2021-02-16
申请号:US16499436
申请日:2018-04-03
Applicant: TCI CO., LTD
Inventor: Yung-Hsiang Lin , I-Hui Chen , Kai-Wen Kan , Fu Chen Liu , Ciao-Ting Chen
IPC: A61K36/00 , A61K36/185 , A23L33/105 , A61K9/00 , A61K9/08 , A61K9/48 , A61P3/04 , A61K31/01 , A61K31/015 , A61K36/21 , A61K36/258 , A61K36/31 , A61K36/45 , A61K36/48 , A61K36/53 , A61K36/67 , A61K36/73 , A61K36/74 , A61K36/752 , A61K36/815 , A61K36/82 , A61K36/87 , A61K36/886 , A61K36/8962 , A61K36/9066 , A61K8/9789 , A61P17/16 , A61Q19/00 , A23F3/16 , A61K8/97 , A61Q17/04 , A61P19/04 , A61Q19/08
Abstract: The present invention provides a method of a composition containing plant extracts for enhancing the gene expression level of TGM1, KRT, AQP3, FLG, GBA, and HAS. Compared to a single plant extract, the combination of the plant extracts of the present invention can more effectively enhance the expression level of skin moisturizing genes. The plant extracts constituting the composition include: an extract of spinach, blueberry, Pu-erh tea, or Four Seasons Spring tea.
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公开(公告)号:US20180296627A1
公开(公告)日:2018-10-18
申请号:US15947914
申请日:2018-04-09
Applicant: TCI CO., LTD
Inventor: Yung-Hsiang Lin , I-Hui Chen , Kai-Wen Kan
Abstract: The present invention provides a method for reducing the expressions of the sterol regulatory element-binding protein 1C (SREBP-1C), acetyl-CoA carboxylase (ACC), and stearoyl-CoA desaturase 1 (SCD-1), comprising administering to a subject a composition comprising an effective amount of a longan pericarp extract. The longan pericarp extract significantly inhibits lipogenesis, reduces the glutamic-pyruvic transaminase (GPT) index, and protects the liver.
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8.
公开(公告)号:US10034844B2
公开(公告)日:2018-07-31
申请号:US15404069
申请日:2017-01-11
Applicant: TCI CO., LTD.
Inventor: Yung-Hsiang Lin , I-Hui Chen , Hui-Hsin Shih , Yun-Ching Tsai , Qiao-Ting Chen
IPC: A61K31/19
CPC classification number: A61K31/19
Abstract: A method for enhancing immunity, inhibiting allergic reaction, and/or inhibiting autoimmune reaction is provided. The method comprises administering to a subject in need an effective amount of a compound of formula (I):
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公开(公告)号:US11752183B2
公开(公告)日:2023-09-12
申请号:US16499990
申请日:2018-04-03
Applicant: TCI CO., LTD
Inventor: Yung-Hsiang Lin , I-Hui Chen , Kai-Wen Kan , Fu Chen Liu , Ciao-Ting Chen
IPC: A61K36/185 , A23L33/105 , A61K9/00 , A61K9/08 , A61K9/48 , A61P3/04 , A61K31/01 , A61K31/015 , A61K36/21 , A61K36/258 , A61K36/31 , A61K36/45 , A61K36/48 , A61K36/53 , A61K36/67 , A61K36/73 , A61K36/74 , A61K36/752 , A61K36/815 , A61K36/82 , A61K36/87 , A61K36/886 , A61K36/8962 , A61K36/9066 , A61K8/9789 , A61P17/16 , A61Q19/00 , A23F3/16 , A61K8/97 , A61Q17/04 , A61P19/04 , A61Q19/08
CPC classification number: A61K36/185 , A23F3/163 , A23L33/105 , A61K8/97 , A61K8/9789 , A61K9/0056 , A61K9/0095 , A61K9/08 , A61K9/48 , A61K31/01 , A61K31/015 , A61K36/21 , A61K36/258 , A61K36/31 , A61K36/45 , A61K36/48 , A61K36/53 , A61K36/67 , A61K36/73 , A61K36/74 , A61K36/752 , A61K36/815 , A61K36/82 , A61K36/87 , A61K36/886 , A61K36/8962 , A61K36/9066 , A61P3/04 , A61P17/16 , A61P19/04 , A61Q17/04 , A61Q19/007 , A61Q19/08 , A23V2002/00
Abstract: Provided is a plant extract-containing composition for reducing skin damage caused by ultraviolet radiation. The composition includes a combination of extracts of spinach, black tea, green tea, Pu-erh tea, Four Seasons Spring tea, red wine, blueberry, grape seeds, citrus, or green coffee beans.
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公开(公告)号:US10933107B2
公开(公告)日:2021-03-02
申请号:US16499473
申请日:2018-04-03
Applicant: TCI CO., LTD
Inventor: Yung-Hsiang Lin , I-Hui Chen , Kai-Wen Kan , Fu Chen Liu , Ciao-Ting Chen
IPC: A61K36/00 , A61K36/185 , A23L33/105 , A61K9/00 , A61K9/08 , A61K9/48 , A61P3/04 , A61K31/01 , A61K31/015 , A61K36/21 , A61K36/258 , A61K36/31 , A61K36/45 , A61K36/48 , A61K36/53 , A61K36/67 , A61K36/73 , A61K36/74 , A61K36/752 , A61K36/815 , A61K36/82 , A61K36/87 , A61K36/886 , A61K36/8962 , A61K36/9066 , A61K8/9789 , A61P17/16 , A61Q19/00 , A23F3/16 , A61K8/97 , A61Q17/04 , A61P19/04 , A61Q19/08
Abstract: Provided is a composition comprising a plant extract. The plant extract includes a citrus extract and a green tea extract. The extract combination can effectively increase expression of GLUT4 gene.
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