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公开(公告)号:US12097228B1
公开(公告)日:2024-09-24
申请号:US18381542
申请日:2023-10-18
IPC分类号: A61K36/00 , A61K9/00 , A61K31/722 , A61K35/02 , A61K35/748 , A61P17/02
CPC分类号: A61K35/748 , A61K9/0014 , A61K31/722 , A61K35/02 , A61P17/02
摘要: A combination of cyanobacteria, chitosan, and plant extracts for wound healing, eliminating pathogen bacteria, or promoting antioxidant activity is provided. The cyanobacteria my be a Spirulina platensis extract and the plant extract may be shilajit.
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公开(公告)号:US20240024358A1
公开(公告)日:2024-01-25
申请号:US18223252
申请日:2023-07-18
申请人: ELANCO US INC.
发明人: Robert Musser , Kim Friesen , Ran Song
摘要: The present invention provides methods of improve efficiency, growth, and performance in an animal by orally administering to the animal an effective amount of a therapeutic clay. The methods can reduce embryonic loss, increase litter size, increase the number of live births, improve the immune status of the maternal animal, reduce the concentration of maternal fecal amino acids, reduce the concentration of maternal fecal short-chained amino acid, increasing litter birth weight in the maternal animal, increase the amount of young animal colostrum intake, reduce young animal pre-weaning mortality, reduce the number of young animals lost due to low viability, reduce the number of weaned young animals, improve the immune status of young animals at weaning, reduce the number of lightweight young animals from nursery to market, increase the number of young animals marketed per sow, and increase calculated litter weight gain.
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公开(公告)号:US20230380462A1
公开(公告)日:2023-11-30
申请号:US18032350
申请日:2021-10-20
发明人: SHINSUKE KISHIDA , KOTARO FUJIOKA , ATSUSHI MASUDA , SAE KORO , HUANG CHUN-MING
IPC分类号: A23L19/00 , A61K35/02 , A61K31/015 , A61K31/07 , A61K31/51 , A61K31/525 , A61K31/4415 , A61K31/355 , A61K31/455 , A61K33/06 , A61K33/42 , A61K33/00 , A61K33/34 , A61K31/198 , A61K31/405 , A61K31/4172 , A61K31/401 , A23L33/135
CPC分类号: A23L19/00 , A61K35/02 , A61K31/015 , A61K31/07 , A61K31/51 , A61K31/525 , A61K31/4415 , A61K31/355 , A61K31/455 , A61K33/06 , A61K33/42 , A61K33/00 , A61K33/34 , A61K31/198 , A61K31/405 , A61K31/4172 , A61K31/401 , A23L33/135
摘要: A prebiotic food product which increases a short-chain fatty acid in an intestine is provided, where the prebiotic food product mainly contains a fermented composition obtained by fermenting and maturing a plurality of ingredients including fruits, citrus, root vegetables such as a burdock and a carrot, cereals, sesames, seaweeds and saccharoses.
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公开(公告)号:US11786602B2
公开(公告)日:2023-10-17
申请号:US17468308
申请日:2021-09-07
发明人: Jolanta Grembecka , Szymon Klossowski , Jing Deng , Tomasz Cierpicki , Hao Li , Hongzhi Miao , Trupta Purohit , EunGi Kim , Dong Chen
IPC分类号: A61K47/64 , A61K31/404 , A61K31/454 , A61K31/4545 , A61K35/02 , A61K38/45 , C07D309/24 , C07D471/04 , A61K9/00 , A61P35/02 , A61K47/54 , C07D209/24
CPC分类号: A61K47/64 , A61K9/0019 , A61K9/0053 , A61K31/404 , A61K31/454 , A61K31/4545 , A61K38/45 , A61K47/545 , A61K47/556 , A61P35/02 , C07D209/24 , C07D471/04 , C12Y203/02
摘要: Provided herein are small molecules comprising a first domain that binds to ASH1L and a second domain that facilitates ASH1L degradation. In particular, ASH1L-targeting proteolysis targeting chimeras (PROTACs) and methods of use thereof for the treatment of disease (e.g., acute leukemia, solid cancers and other diseases dependent on activity of ASH1L) are provided.
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公开(公告)号:US11649438B2
公开(公告)日:2023-05-16
申请号:US17238741
申请日:2021-04-23
IPC分类号: A61K35/17 , A61K39/395 , A61P35/02 , A61K35/02 , C12N15/13 , C12N5/0783 , A61P35/00 , C07K14/725 , C07K16/28 , C12N9/22 , C12N15/11 , C12N15/86 , C07K14/705 , C07K14/74 , A61K47/68 , A61K51/10 , A61K38/00 , A61K39/00
CPC分类号: C12N5/0636 , A61K35/17 , A61K47/6849 , A61K51/1027 , A61P35/00 , C07K14/7051 , C07K14/70517 , C07K14/70521 , C07K14/70539 , C07K14/70578 , C07K16/2803 , C07K16/2875 , C07K16/2878 , C12N9/22 , C12N15/11 , C12N15/86 , A61K38/00 , A61K2039/505 , A61K2039/5156 , C07K2317/565 , C07K2317/622 , C07K2317/74 , C07K2317/76 , C07K2319/02 , C07K2319/03 , C07K2319/30 , C07K2319/33 , C12N2310/20 , C12N2510/00 , C12N2750/14143 , C12N2800/80
摘要: Provided herein, in some embodiments, are methods and compositions (e.g., cell compositions) for the treatment of cancer.
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公开(公告)号:US11607391B2
公开(公告)日:2023-03-21
申请号:US13879178
申请日:2009-09-25
摘要: Provided is a microsphere comprising a bead coated with a first calcium-containing mineral. Also provided is a method of producing a microsphere. Additionally, a method of administering a compound to a vertebrate is provided.
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公开(公告)号:US11364274B2
公开(公告)日:2022-06-21
申请号:US16807446
申请日:2020-03-03
发明人: M Vijayabhanu Shetty
IPC分类号: A61K36/00 , A61K36/899 , A61K36/48 , A61K36/59 , A61K9/20 , A61K35/02 , A61K33/00 , A61P15/02 , A61K36/736
摘要: Composition for the treatment and management of Polycystic ovarian syndrome and method of preparation thereof are disclosed herein. The disclosed Herbal composition includes herbs and minerals which facilitate in treating PCOS and PCOS associated symptoms. The composition comprises Saraca indica, Symplocos racemosa, Boerhavia diffusa, Tinospora cordifolia, Terminalia arjuna, Saccharum officinarum and Commiphora mukul, or extracts thereof; Shilajit; and bhasmas. The disclosed composition may also be instrumental in improving general reproductive health of an individual.
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公开(公告)号:US20220142204A1
公开(公告)日:2022-05-12
申请号:US17524709
申请日:2021-11-11
申请人: NutriQuest, LLC
发明人: Kim Friesen , Ran Song , Chad Hagen , Jeff Hansen
摘要: Feed additive compositions and methods of using the additives to improve the performance of an adult animal are disclosed. Improved performance can include reducing maintenance nutrient requirements, improving growth performance, reducing the energy required for intestinal maintenance, reducing the energy required for weight gain, reduced morbidity, increasing growth rate, improving feed conversion, improving the average daily gain (ADG), improving the efficiency of nutrient utilization, increasing volatile fatty acid production, improving energy use from volatile fatty acids, increasing ending body weight, improved intestinal health, increased relative abundance of Bifidobacterium in the intestines, or combinations thereof.
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公开(公告)号:US20220062361A1
公开(公告)日:2022-03-03
申请号:US17008726
申请日:2020-09-01
申请人: Suresh MAHAWAR
发明人: Suresh MAHAWAR
IPC分类号: A61K36/235 , A61K35/02 , A61K9/20 , A61K9/48 , A61K9/14 , A61K9/00 , A23L33/105 , A23L33/00
摘要: The present invention relates to a herbal supplement composition for improved digestion of food in a subject in need having range of ingredient concentrations comprising asafoetida between 0.1 gm and 5 gm; Foeniculum vulgare seeds powder between 5 mg and 15 gm; Trachyspermum ammi seeds powder between 5 mg and 15 gm; and shilajit powder between 5 mg and 300 mg. Furthermore, the present invention relates to a method of improving digestion of food in a subject in need comprising orally administering a composition containing asafetida, Foeniculum vulgare seeds powder, Trachyspermum ammi seeds powder and shilajit powder.
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10.
公开(公告)号:US11174318B2
公开(公告)日:2021-11-16
申请号:US16449255
申请日:2019-06-21
IPC分类号: C07K16/28 , A61K39/00 , A61K47/68 , A61P35/00 , A61K35/02 , C07K14/725 , C07K14/705 , G01N33/574 , A61K38/00
摘要: The present invention relates to a monoclonal mouse antibody produced by the hybridoma cell deposited under ICLC accession number ICLC PD n° 16001. Furthermore, the invention relates to an antibody comprising a heavy chain variable region comprising complementarity determining regions CDRH1, CDRH2 and CDRH3, and a light chain variable region comprising complementarity determining regions CDRL1, CDRL2 and CDRL3, wherein CDRH1, CDRH2, CDRH3, CDRL1, CDRL2, and CDRL3 comprise the amino acid sequences GFTFSSFGMH (SEQ ID NO: 1), YISSGSGNFYYVDTVKG (SEQ ID NO: 43), STYYHGSRGAMDY (SEQ ID NO: 3), SASSSVSSMYWY (SEQ ID NO: 4), DTSKMAS (SEQ ID NO: 5), and QQWSSYPPIT (SEQ ID NO: 6), respectively. In addition, the invention relates to antibodies recognizing the same epitope.
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