公开(公告)号：US12111248B2

公开(公告)日：2024-10-08

申请号：US16382489

申请日：2019-04-12

申请人： Labrador Diagnostics LLC

发明人： Karan Mohan ,  Chinmay Pangarkar ,  James R. Wasson

IPC分类号： G01N21/03 ,  B01L3/00 ,  B01L9/00 ,  G01N1/30 ,  G01N15/10 ,  G01N21/05 ,  G01N21/17 ,  G01N21/27 ,  G01N21/64 ,  G01N33/487 ,  G01N33/49 ,  G01N33/50 ,  G01N33/569 ,  G02B7/09 ,  G02B21/00 ,  G02B21/08 ,  G02B21/12 ,  G02B21/16 ,  G02B21/24 ,  G02B21/34 ,  G02B21/36 ,  G01N15/01 ,  G01N15/14

CPC分类号： G01N21/0303 ,  B01L3/502715 ,  B01L3/5085 ,  B01L9/523 ,  G01N1/30 ,  G01N15/1012 ,  G01N21/05 ,  G01N21/17 ,  G01N21/27 ,  G01N21/6428 ,  G01N21/645 ,  G01N21/6458 ,  G01N21/6486 ,  G01N33/487 ,  G01N33/49 ,  G01N33/5005 ,  G01N33/56966 ,  G01N33/56972 ,  G02B7/09 ,  G02B21/00 ,  G02B21/0076 ,  G02B21/088 ,  G02B21/125 ,  G02B21/16 ,  G02B21/244 ,  G02B21/34 ,  G02B21/365 ,  G02B21/367 ,  B01L2300/0654 ,  B01L2300/168 ,  G01N15/01 ,  G01N2015/1014 ,  G01N2015/1486 ,  G01N2021/1738 ,  G01N2021/6439 ,  G01N2201/061 ,  G01N2201/068 ,  G01N2201/12 ,  G01N2333/70589 ,  G01N2333/70596

摘要： Methods, devices, apparatus, and systems are provided for image analysis. Methods of image analysis may include observation, measurement, and analysis of images of biological and other samples; devices, apparatus, and systems provided herein are useful for observation, measurement, and analysis of images of such samples. The methods, devices, apparatus, and systems disclosed herein provide advantages over other methods, devices, apparatus, and systems.

公开(公告)号：US12092520B2

公开(公告)日：2024-09-17

申请号：US17598731

申请日：2020-03-25

申请人： Ushio Denki Kabushiki Kaisha

发明人： Takuma Yokoyama

IPC分类号： G01J3/10 ,  G01N21/27 ,  G02B27/09 ,  G02B27/10

CPC分类号： G01J3/10 ,  G01N21/27 ,  G02B27/0905 ,  G02B27/1013 ,  G01N2201/061 ,  G01N2201/068 ,  G01N2201/08

摘要： Broadband pulsed light from a broadband pulsed light source is pulse-stretched such that an elapsed time and a wavelength in a pulse correspond to each other on a one-to-one basis, and is radiated to an object. The light transmitted through the object is received by a light receiver and converted into a spectrum by a calculator. The broadband pulsed light is divided according to a wavelength by dividing elements, and is pulse-stretched by two fibers having different dispersion characteristics or received by two light receivers having different characteristics.

公开(公告)号：US12061149B2

公开(公告)日：2024-08-13

申请号：US17324423

申请日：2021-05-19

申请人： YSI, INC.

发明人： Kevin Flanagan

IPC分类号： G01N21/64 ,  G01N21/47 ,  G01N21/53 ,  G01N21/82 ,  G01N33/08 ,  G01N33/18 ,  H04N25/46

CPC分类号： G01N21/6456 ,  G01N21/4785 ,  G01N21/532 ,  G01N21/64 ,  G01N21/82 ,  G01N33/08 ,  G01N33/18 ,  H04N25/46 ,  G01N2021/6473 ,  G01N2021/6491 ,  G01N2201/061 ,  G01N2201/0633 ,  G01N2201/0636 ,  G01N2201/126 ,  G01N2201/12761 ,  G01N2201/12792

摘要： A swept frequency fluorometer having a signal processor or processing module configured to:
receive signaling containing information about reflected light off one or more fluorescence species-of-interest in a liquid sample that is swept with light having a variable frequency range, the information including a characteristic optical frequency corresponding to a fluorescence species-of-interest in the liquid, and a characteristic/lifetime optical frequency corresponding to a distinct fluorescence lifetime in which the fluorescence species-of-interest remains in an excited state; and
provide corresponding signaling containing information about an identity of the fluorescence species-of-interest detected and distinguished from overlapping fluorescence species in the liquid using the characteristic/lifetime optical frequency, based upon the signaling received.

公开(公告)号：US20240230525A1

公开(公告)日：2024-07-11

申请号：US18561832

申请日：2022-06-07

申请人： trinamiX GmbH

发明人： Felix SCHMIDT ,  Felix Berno MUELLER ,  David KAESTEL ,  Martin CALABEK ,  Uemit ACKU ,  Celal Mohan OEGUEN

IPC分类号： G01N21/31

CPC分类号： G01N21/31 ,  G01N2201/061 ,  G01N2201/08

摘要： Disclosed herein is a spectroscopic light source. The spectroscopic light source includes:



at least one light emitting element;
at least one electronic circuit configured for applying electric power to the light emitting element; and
at least one housing, where the housing at least partially surrounds the light emitting element; and
at least two output channels going through the housing, where each one of the output channels is configured for decoupling at least one light beam from the spectroscopic light source.




The spectroscopic light source is configured for independently controlling each one of the output channels.

公开(公告)号：US12031916B2

公开(公告)日：2024-07-09

申请号：US17962123

申请日：2022-10-07

申请人： LIFE TECHNOLOGIES CORPORATION

发明人： Mingsong Chen ,  Mauro Aguanno ,  Kuan Moon Boo ,  Woon Liang Terence Soh ,  Jacob K. Freudenthal ,  Jeffrey A. Marks

IPC分类号： G01N21/64 ,  G01N21/03 ,  G01N21/27

CPC分类号： G01N21/6486 ,  G01N21/0332 ,  G01N21/274 ,  G01N21/645 ,  G01N21/6452 ,  G01N2201/061 ,  G01N2201/0624 ,  G01N2201/0627 ,  G01N2201/121

摘要： An instrument for processing and/or measuring a biological process comprises a sample processing system and an excitation source exhibiting a spectral function of output power or intensity verses wavelength of output power or intensity. The spectral function has a minima wavelength corresponding to a local minima value of the output power or intensity; a first maxima wavelength corresponding to a first local maxima of output power or intensity, the output power or intensity at the first local maxima being greater than the output power or intensity at any wavelength less than the minima wavelength; a second maxima wavelength corresponding to a second local maxima of output power or intensity, the output power or intensity at the second local maxima being greater than the output at any wavelength greater than the minima wavelength; the minima wavelength is between the first maxima wavelength and the second maxima wavelength.

公开(公告)号：US20240210317A1

公开(公告)日：2024-06-27

申请号：US18412346

申请日：2024-01-12

申请人： CELLSBIN, INC.

发明人： Ali KABIRI

IPC分类号： G01N21/47 ,  B01L3/00 ,  G06T17/00

CPC分类号： G01N21/4788 ,  B01L3/502715 ,  G06T17/00 ,  G01N2201/061

摘要： One aspect provided herein is an analyte processing device, comprising one or more flow channels, wherein at least one flow channel of the one or more flow channels comprise an analyte processing area; one or more excitation sources in optical communication with the analyte processing area and comprising an optical path from the one or more excitation sources to the analyte processing area; and one or more photodetectors in optical communication with the analyte processing area, wherein the optical path comprises a light scattering control system.

公开(公告)号：US20240201093A1

公开(公告)日：2024-06-20

申请号：US18140406

申请日：2023-04-27

申请人： SAMSUNG ELECTRONICS CO., LTD.

发明人： Wooram HONG ,  Hyukju KWON ,  Gahee KIM ,  Won Seok OH ,  Hyunjeong JEON ,  Hyun Do CHOI ,  Minsu CHANG ,  Younsuk CHOI

IPC分类号： G01N21/85 ,  G01N21/3577

CPC分类号： G01N21/85 ,  G01N21/3577 ,  G01N2021/8557 ,  G01N2201/0231 ,  G01N2201/061

摘要： The present disclosure provides optical monitoring devices. In some embodiments, the optical monitoring device includes a heating stirrer, a floating barrel, and a support body arranged to support the floating barrel. The floating barrel includes a barrel body facing the heating stirrer and spaced apart from the heating stirrer by a gap, a cavity provided in the barrel body and configured to accommodate at least one of a vessel and a conduit, an irradiator arranged in the barrel body and configured to radiate light to the cavity, and a light receiver arranged in the barrel body, aligned with the irradiator and the cavity, and configured to receive light from the cavity.

公开(公告)号：US11986295B1

公开(公告)日：2024-05-21

申请号：US18455492

申请日：2023-08-24

申请人： Apollon Inc.

发明人： Miyeon Jue ,  Young Kyu Kim ,  Aram Hong

IPC分类号： A61B5/1455 ,  A61B5/00 ,  A61B5/145 ,  G01N21/65 ,  G01N33/49

CPC分类号： A61B5/14532 ,  A61B5/0002 ,  A61B5/1455 ,  G01N21/65 ,  G01N33/49 ,  A61B5/6801 ,  G01N2201/061 ,  G01N2201/127

摘要： Disclosed is a blood glucose level measuring apparatus utilizing a Raman spectrum includes a housing defining an interior accommodation space, a light source part disposed in the housing, and that irradiates light to a subject, a light receiving part disposed in the housing, and that receives the reflected and scattered light from the subject and acquires a Raman spectrum, and a processor disposed in the housing, and that extracts information on glucose, proteins, and fats of the subject by utilizing an area of a peak included in the Raman spectrum. The processor performs a calibration by controlling the light source part and the light receiving part when the blood glucose level measuring apparatus starts to be driven or is mounted on a body of a user.

公开(公告)号：US20240142389A1

公开(公告)日：2024-05-02

申请号：US18382046

申请日：2023-10-19

申请人： SEMES CO., LTD.

发明人： Jeong Hoon HAN ,  Oh Yeol KWON ,  Jun Hyun LIM ,  Dong Min PARK

IPC分类号： G01N21/95 ,  G01N21/88 ,  H01L21/66

CPC分类号： G01N21/9501 ,  G01N21/8806 ,  G01N21/8851 ,  H01L22/24 ,  G01N2201/061

摘要： A substrate inspection apparatus inspecting substrates using a vision system, which includes a camera module and an illumination module, and a substrate treatment system including the substrate inspection apparatus are provided. The substrate treatment system includes: a first substrate treatment apparatus; a second substrate treatment apparatus; a transfer unit transporting a container with a plurality of substrates accommodated therein from the first substrate treatment apparatus to the second substrate treatment apparatus; and a substrate inspection apparatus inspecting the substrates, wherein the substrate inspection apparatus includes an illumination module, which illuminates in a direction where the substrates are located, a camera module, which acquires images related to the substrates when the substrates are illuminated, and a control module, which inspects the substrates based on the images.

公开(公告)号：US20240118260A1

公开(公告)日：2024-04-11

申请号：US18528948

申请日：2023-12-05

申请人： UNM RAINFOREST INNOVATIONS

发明人： Steven R.J. BRUECK ,  Jeremy Scott EDWARDS ,  Alexander NEUMANN ,  Yuliya KUZNETSOVA ,  Edgar A. MENDOZA

IPC分类号： G01N33/487 ,  B01L3/00 ,  C12Q1/6869 ,  C23C16/34 ,  C23C16/455 ,  C23C16/50 ,  G01N21/65

CPC分类号： G01N33/48721 ,  B01L3/502707 ,  B01L3/502761 ,  C12Q1/6869 ,  C23C16/345 ,  C23C16/45525 ,  C23C16/50 ,  G01N21/65 ,  B01L2200/0663 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/046 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2300/0896 ,  B01L2300/16 ,  B01L2300/168 ,  B01L2400/0421 ,  G01N2021/653 ,  G01N2201/061

摘要： Methods and apparatus for long read, label-free, optical nanopore long chain molecule sequencing. In general, the present disclosure describes a novel sequencing technology based on the integration of nanochannels to deliver single long-chain molecules with widely spaced (>wavelength), ˜1-nm aperture “tortuous” nanopores that slow translocation sufficiently to provide massively parallel, single base resolution using optical techniques. A novel, directed self-assembly nanofabrication scheme using simple colloidal nanoparticles is used to form the nanopore arrays atop nanochannels that unfold the long chain molecules. At the surface of the nanoparticle array, strongly localized electromagnetic fields in engineered plasmonic/polaritonic structures allow for single base resolution using optical techniques.