公开(公告)号：US12085500B2

公开(公告)日：2024-09-10

申请号：US18111740

申请日：2023-02-20

申请人： Apple Inc.

发明人： Miikka M. Kangas ,  Mark Alan Arbore ,  David I. Simon ,  Michael J. Bishop ,  James W. Hillendahl ,  Robert Chen

IPC分类号： G01N21/27 ,  G01J3/02 ,  G01J3/32 ,  G01J3/36 ,  G01J3/42 ,  G01J3/433 ,  G01J3/447 ,  G01N21/21 ,  G01N21/35 ,  G01N21/47 ,  G01N21/49

CPC分类号： G01N21/276 ,  G01J3/0286 ,  G01J3/32 ,  G01J3/36 ,  G01J3/42 ,  G01J3/433 ,  G01J3/447 ,  G01N21/35 ,  G01N21/474 ,  G01N21/4785 ,  G01N21/21 ,  G01N2021/4709 ,  G01N2021/4778 ,  G01N21/49 ,  G01N2201/0221 ,  G01N2201/12707 ,  G01N2201/12723

摘要： This relates to systems and methods for measuring a concentration and type of substance in a sample at a sampling interface. The systems can include a light source, optics, one or more modulators, a reference, a detector, and a controller. The systems and methods disclosed can be capable of accounting for drift originating from the light source, one or more optics, and the detector by sharing one or more components between different measurement light paths. Additionally, the systems can be capable of differentiating between different types of drift and eliminating erroneous measurements due to stray light with the placement of one or more modulators between the light source and the sample or reference. Furthermore, the systems can be capable of detecting the substance along various locations and depths within the sample by mapping a detector pixel and a microoptics to the location and depth in the sample.

公开(公告)号：US12061149B2

公开(公告)日：2024-08-13

申请号：US17324423

申请日：2021-05-19

申请人： YSI, INC.

发明人： Kevin Flanagan

IPC分类号： G01N21/64 ,  G01N21/47 ,  G01N21/53 ,  G01N21/82 ,  G01N33/08 ,  G01N33/18 ,  H04N25/46

CPC分类号： G01N21/6456 ,  G01N21/4785 ,  G01N21/532 ,  G01N21/64 ,  G01N21/82 ,  G01N33/08 ,  G01N33/18 ,  H04N25/46 ,  G01N2021/6473 ,  G01N2021/6491 ,  G01N2201/061 ,  G01N2201/0633 ,  G01N2201/0636 ,  G01N2201/126 ,  G01N2201/12761 ,  G01N2201/12792

摘要： A swept frequency fluorometer having a signal processor or processing module configured to:
receive signaling containing information about reflected light off one or more fluorescence species-of-interest in a liquid sample that is swept with light having a variable frequency range, the information including a characteristic optical frequency corresponding to a fluorescence species-of-interest in the liquid, and a characteristic/lifetime optical frequency corresponding to a distinct fluorescence lifetime in which the fluorescence species-of-interest remains in an excited state; and
provide corresponding signaling containing information about an identity of the fluorescence species-of-interest detected and distinguished from overlapping fluorescence species in the liquid using the characteristic/lifetime optical frequency, based upon the signaling received.

公开(公告)号：US12038378B2

公开(公告)日：2024-07-16

申请号：US17566076

申请日：2021-12-30

申请人： ABB Schweiz AG

发明人： Benjamin Carr ,  Andrew James Bowen

IPC分类号： G01N21/51 ,  G01N21/47

CPC分类号： G01N21/51 ,  G01N21/4785

摘要： A system and method for self-calibrating optical turbidity measurements includes a housing comprising a cavity with an inner wall having an essentially straight section and an opening for the medium. An optical standard is moveable between first and second sections within the essentially straight section, and a light source and a light sensor, arranged at the first section and configured to measure the turbidity of the medium, when the optical standard is at the second section, and configured to measure the turbidity of the optical standard and to determine, as a function of the measured turbidity, a calibration coefficient for performing a self-calibration, when the optical standard is at the first section.

公开(公告)号：US11982618B2

公开(公告)日：2024-05-14

申请号：US17084296

申请日：2020-10-29

申请人： SAMSUNG ELECTRONICS CO., LTD.

发明人： Sung Hyun Nam ,  Hyeong Seok Jang ,  Jin Young Park

IPC分类号： G01N21/47 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/1495 ,  G01J3/02 ,  G01J3/10

CPC分类号： G01N21/4785 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1495 ,  G01J3/021 ,  G01J3/0297 ,  G01J3/10 ,  A61B2562/0238

摘要： A method of calibrating an optical sensor may include acquiring a first characteristic for an external light source through a detector of an optical sensor while an internal light source of the optical sensor is turned off; driving the internal light source; acquiring a second characteristic for the internal light source and the external light source through the detector, based on driving the internal light source; and acquiring a reference characteristic of the internal light source, for calculation of an absorbance of an object, based on the first characteristic and the second characteristic.

公开(公告)号：US11867631B2

公开(公告)日：2024-01-09

申请号：US17527828

申请日：2021-11-16

申请人： OndaVia, Inc.

发明人： Mark C. Peterman ,  Merwan Benhabib ,  Samuel Kleinman

IPC分类号： G01N21/65 ,  G01N21/47 ,  G01N21/63 ,  G01N21/66 ,  G01N33/18 ,  G01J3/02 ,  G01J3/18 ,  G01J3/44 ,  B01L3/00 ,  G01N27/447 ,  G01N30/60 ,  G01N21/49 ,  G01N21/68 ,  G01N21/27 ,  G01N30/00 ,  G01J3/28

CPC分类号： G01N21/65 ,  B01L3/502715 ,  B01L3/502761 ,  G01J3/02 ,  G01J3/0256 ,  G01J3/0291 ,  G01J3/18 ,  G01J3/44 ,  G01J3/4412 ,  G01N21/276 ,  G01N21/47 ,  G01N21/4785 ,  G01N21/49 ,  G01N21/63 ,  G01N21/658 ,  G01N21/66 ,  G01N21/68 ,  G01N27/44704 ,  G01N27/44791 ,  G01N30/6095 ,  G01N33/18 ,  B01L2200/04 ,  B01L2200/0652 ,  B01L2200/12 ,  B01L2300/0627 ,  B01L2300/0636 ,  B01L2300/0654 ,  B01L2300/0681 ,  B01L2300/087 ,  B01L2300/0867 ,  B01L2400/0418 ,  B01L2400/0421 ,  G01J2003/2866 ,  G01J2003/2879 ,  G01N30/6065 ,  G01N2021/651 ,  G01N2021/656 ,  G01N2030/0095 ,  G01N2201/0221 ,  G01N2201/13

摘要： A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port, a cartridge for input to the cartridge receiving port having a sample input and a channel, where the channel includes a mixture of Raman-scattering nanoparticles and a calibration solution, where the calibration solution includes chemical compounds capable of interacting with a sample under test input to the cartridge and the Raman-scattering nanoparticles, and an optical detection system in the housing, where the optical detection system is capable of providing an illuminated electric field, where the illuminating electric field is capable of being used for Raman spectroscopy with the Raman-scattering nanoparticles and the calibration solution to analyze the sample under test input to the cartridge.

公开(公告)号：US20190250521A1

公开(公告)日：2019-08-15

申请号：US16398175

申请日：2019-04-29

申请人： KLA-Tencor Corporation

发明人： Eran Amit ,  Raviv YOHANAN

IPC分类号： G03F7/20 ,  G01N21/95 ,  G01N21/47

CPC分类号： G03F7/70633 ,  G01N21/47 ,  G01N21/4785 ,  G01N21/9501 ,  G01N2201/02 ,  G01N2201/12 ,  G03F7/70683

摘要： Metrology targets, design files, and design and production methods thereof are provided. The targets comprise two or more parallel periodic structures at respective layers, wherein a predetermined offset is introduced between the periodic structures, for example, opposite offsets at different parts of a target. Quality metrics are designed to estimate the unintentional overlay from measurements of a same metrology parameter by two or more alternative measurement algorithms. Target parameters are configured to enable both imaging and scatterometry measurements and enhance the metrology measurements by the use of both methods on the same targets. Imaging and scatterometry target parts may share elements or have common element dimensions. Imaging and scatterometry target parts may be combined into a single target area or may be integrated into a hybrid target using a specified geometric arrangement.

公开(公告)号：US20180306701A1

公开(公告)日：2018-10-25

申请号：US15958771

申请日：2018-04-20

申请人： bioMerieux, Inc.

发明人： Jack R. HOFFMANN, JR. ,  Gregory R. MAES ,  Jeffrey Edward PRICE ,  Jared Ian BULLOCK ,  Samuel B. CRANDALL ,  Jacky S. YAM ,  Christopher George KOCHER ,  Walter J. CLYNES

IPC分类号： G01N21/03 ,  G01N33/487 ,  G01N1/10 ,  G01N21/47

CPC分类号： B01L3/50853 ,  B01L2200/14 ,  B01L2300/0654 ,  B01L2300/0803 ,  B01L2300/12 ,  G01N1/10 ,  G01N15/06 ,  G01N21/01 ,  G01N21/274 ,  G01N21/4738 ,  G01N21/474 ,  G01N21/4785 ,  G01N21/51 ,  G01N21/5907 ,  G01N21/8806 ,  G01N21/93 ,  G01N33/487 ,  G01N2015/0693 ,  G01N2021/0168 ,  G01N2021/4769 ,  G01N2021/598 ,  G01N2201/126 ,  G01N2201/12707

摘要： Provided herein are an optical test platform and corresponding method of manufacturing the same. The test platform may include a shell defining a cavity for receiving a sample tube, a first aperture, and a second aperture. The first aperture and the second aperture of the shell may each be configured to optically couple the cavity with an exterior of the shell. The test platform may further include a first window and a second window embedded in the shell. The first window may seal a first aperture and the second window may seal a second aperture. The first window and second window may each permit the optical coupling of the cavity with the exterior of the shell. The first window and the second window may be optically coupled via the cavity, and the shell may prohibit optical coupling between the first window and the second window through the shell.

公开(公告)号：US20180128747A1

公开(公告)日：2018-05-10

申请号：US15721993

申请日：2017-10-02

申请人： Jun Zhao ,  Xin Jack Zhou

发明人： Jun Zhao ,  Xin Jack Zhou

IPC分类号： G01N21/65 ,  G01N21/27 ,  G01N21/359 ,  G01N21/3577

CPC分类号： G01N21/65 ,  G01N21/274 ,  G01N21/278 ,  G01N21/3577 ,  G01N21/359 ,  G01N21/4785 ,  G01N2021/656

摘要： This invention discloses a Reverse Intensity Correction method for spectral library search to correct for instrument response without the side effect of magnifying the noise in the low responsivity region of test spectra. Instead of applying relative intensity correction to the sample test spectra to match the standardized library spectra, a reverse intensity correction is applied to the standardized library spectra to match the uncorrected sample spectrum. This simple procedural change improves library search performance, especially for dispersive CCD Raman analyzers using NIR excitations, where the instrument response often varies greatly across the spectral range, and SNR in the low responsivity regions is typically poor.

公开(公告)号：US09958383B2

公开(公告)日：2018-05-01

申请号：US14574451

申请日：2014-12-18

申请人： Microsoft Technology Licensing, LLC.

发明人： Michael Anthony Hall ,  Kameron Rausch ,  Abdelrehim Ahmed ,  Beibei Cheng ,  Ben Walker ,  Jonathan Hoof ,  Daniel Kennett

IPC分类号： G01S7/497 ,  G01S17/89 ,  G01N21/47 ,  G01S17/46 ,  A61B5/00 ,  G01S17/00

CPC分类号： G01N21/4738 ,  A61B5/0077 ,  A61B5/44 ,  A61B5/441 ,  G01N21/4785 ,  G01S7/497 ,  G01S17/46 ,  G01S17/89 ,  G06T2207/10028

摘要： An active illumination range camera that acquires a range and a picture image of a scene and provides a reflectance for a feature in the scene responsive to a distance for the feature provided by the range image, a registered irradiance for the feature provided by the picture image and registered irradiance for a region of a calibration surface corresponding to the feature provided by an image of the calibration surface acquired by the range camera.

公开(公告)号：US20180113067A1

公开(公告)日：2018-04-26

申请号：US15486125

申请日：2017-04-12

申请人： Hach Company

发明人： Douglas Ford Royer ,  Charles C. Johnson ,  Andreas Golitz ,  Bas de Heij

IPC分类号： G01N21/03 ,  G01N21/51

CPC分类号： G01N21/0303 ,  G01N21/4785 ,  G01N21/51 ,  G01N2201/068

摘要： An embodiment provides a turbidimeter standard ampule, including: a main part composed of glass and containing therein a formazin solution comprising a formazine polymer diluted in a solvent; the main part including a lens positioned in a bottom edge thereof and permitting entry of light from a turbidimeter; the main part having glass sides and permitting redirected light to exit the glass sides for detection by a photodetector of the turbidimeter; an upper part composed of glass and being attached to the main part; and an opaque cap on the upper part, the opaque cap blocking light from entering the upper part of the ampule. Other embodiments are described and claimed.