公开(公告)号：US20240229084A9

公开(公告)日：2024-07-11

申请号：US18278976

申请日：2022-02-25

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Dong Hyun KIM ,  Jae Kyun KIM ,  Dong Oh HAN

IPC: C12P7/42 ,  C07C67/297

CPC classification number: C12P7/42 ,  C07C67/297

Abstract: The present invention relates to a chemical and biological integrated degradation process for PET, for recycling PET, and, more specifically, the present invention provides a PET upcycling technique for producing a high-value product via a chemical pretreatment process of PET, a TPA and EG production process using an enzyme, and a process for converting TPA and EG to PCA and GLA, respectively.

公开(公告)号：US09688622B1

公开(公告)日：2017-06-27

申请号：US15436320

申请日：2017-02-17

Applicant: Shin-Etsu Chemical Co., Ltd.

Inventor： Takeshi Kinsho ,  Naoki Ishibashi ,  Yusuke Nagae

IPC: C07C69/52 ,  C07C309/66 ,  C07C309/73

CPC classification number: C07C309/66 ,  C07C67/287 ,  C07C67/293 ,  C07C67/297 ,  C07C69/63 ,  C07C69/65 ,  C07C309/73 ,  C07C315/04 ,  C07C317/04 ,  C07C317/14 ,  C07C2601/02 ,  C07C69/24 ,  C07C69/145

Abstract: Provided is a 1-(2-acyloxyethyl)cyclopropyl sulfonate compound of General Formula (2): wherein R1 is a monovalent hydrocarbon group having 1 to 10 carbon atoms and optionally containing one or more unsaturated bonds and Z is a monovalent hydrocarbon group having 1 to 10 carbon atoms and optionally containing one or more unsaturated bonds.

公开(公告)号：US09611211B2

公开(公告)日：2017-04-04

申请号：US14974052

申请日：2015-12-18

Applicant: Shin-Etsu Chemical Co., Ltd.

Inventor： Takeshi Kinsho ,  Naoki Ishibashi ,  Yusuke Nagae

IPC: C07C69/65 ,  C07C309/66 ,  C07C309/73 ,  C07C67/287 ,  C07C67/293 ,  C07C69/63 ,  C07C67/297 ,  C07C315/04 ,  C07C317/04 ,  C07C317/14

CPC classification number: C07C309/66 ,  C07C67/287 ,  C07C67/293 ,  C07C67/297 ,  C07C69/63 ,  C07C69/65 ,  C07C309/73 ,  C07C315/04 ,  C07C317/04 ,  C07C317/14 ,  C07C2601/02 ,  C07C69/24 ,  C07C69/145

Abstract: Provided is a simple, selective and efficient method for producing 4-alkyl-3-methylenebutyl carboxylates such as 7-methyl-3-methylene-7-octenyl propionate. More specifically, provided is, for example, a method for producing a 4-alkyl-3-methylenebutyl carboxylate compound, comprising an acyloxylation step of subjecting a 1-(2-haloethyl)cyclopropyl sulfonate compound (1) to acyloxylation to obtain a 1-(2-acyloxyethyl)cyclopropyl sulfonate compound (2), a halogenation step of subjecting the compound (2) to halogenation involving cyclopropyl-allyl rearrangement to obtain a 3-halomethyl-3-butenyl carboxylate compound (3), and a coupling step of subjecting the compound (3) to a coupling reaction with an organometallic reagent (4) to obtain the 4-alkyl-3-methylenebutyl carboxylate compound (5).

公开(公告)号：US09487471B1

公开(公告)日：2016-11-08

申请号：US14686647

申请日：2015-04-14

Applicant: PROVIVI, INC.

Inventor： Pedro Coelho ,  Peter Meinhold ,  Mike M. Y. Chen

IPC: C07C69/747 ,  A01N53/00

CPC classification number: A01N53/00 ,  C07C45/68 ,  C07C51/60 ,  C07C67/14 ,  C07C67/297 ,  C07C2601/02 ,  C07C2601/10 ,  C07C49/743 ,  C07C61/37 ,  C07C69/747

Abstract: The present invention provides methods for synthesizing pyrethroid compounds. The methods include forming a first reaction comprising an olefin and an allethrolone-type unsaturated alcohol under conditions sufficient to form a metathesis product and converting the metathesis product to the pyrethroid. Methods of the invention can be used to prepare compounds including pyrethrin I, cinerin I, jasmolin I, pyrethrin II, cinerin II, and jasmolin II as well as other synthetic pyrethroid compounds. Insecticidal compositions and methods for controlling insects are also described.

Abstract translation: 本发明提供合成拟除虫菊酯化合物的方法。 所述方法包括在足以形成复分解产物并将复分解产物转化为拟除虫菊酯的条件下形成包含烯烃和抗坏血酸类型不饱和醇的第一反应。 本发明的方法可用于制备包括除虫菊酯I，cinerin I，jasmolin I，除虫菊酯II，cinerin II和jasmolin II以及其他合成拟除虫菊酯化合物的化合物。 还描述了用于防治昆虫的杀虫组合物和方法。

公开(公告)号：US09296718B2

公开(公告)日：2016-03-29

申请号：US14471682

申请日：2014-08-28

Applicant: Lonza Ltd

Inventor： Christian Noti ,  Guixian Hu ,  Barry Jackson

IPC: C07D319/00 ,  C07D319/06 ,  C07C67/03 ,  C07C67/32 ,  C07C67/05 ,  C07C67/297 ,  C07D207/34 ,  C07D239/42

CPC classification number: C07D319/06 ,  C07C67/03 ,  C07C67/05 ,  C07C67/297 ,  C07C67/32 ,  C07D207/34 ,  C07D239/42 ,  C07C69/716

Abstract: The invention discloses a method for the preparation of tert-butyl 6-chloro-3,5-dioxohexanoate from Meldrum's acid derivative and its use for the preparation of tert-butyl (4R,6S)-(6-hydroxymethyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate (BHA), Rosuvastatin and Atorvastatin.

Abstract translation: 本发明公开了一种从Meldrum酸衍生物制备6-氯-3,5-二氧代己酸叔丁酯的方法及其用于制备（4R，6S） - （6-羟甲基-2,2-二甲基 - 二甲基-1,3-二恶烷-4-基）乙酸酯（BHA），罗苏伐他汀和阿托伐他汀。

公开(公告)号：US20150298111A1

公开(公告)日：2015-10-22

申请号：US14346865

申请日：2012-09-23

Applicant: Tomasz WDOWIK ,  Cezary SAMOJLOWICZ ,  Magdalena JAWICZUK ,  Karol GRELA

Inventor： Tomasz WDOWIK ,  Cezary SAMOJLOWICZ ,  Magdalena JAWICZUK ,  Karol GRELA

IPC: B01J31/22 ,  C07C67/333 ,  C08G61/08 ,  C07C29/56 ,  C07C67/297 ,  C07D307/28 ,  C07F15/00 ,  C07D207/48

CPC classification number: B01J31/2269 ,  B01J31/2273 ,  B01J31/2278 ,  B01J2231/52 ,  B01J2231/54 ,  B01J2231/543 ,  B01J2231/643 ,  B01J2531/821 ,  C07C29/56 ,  C07C67/297 ,  C07C67/333 ,  C07D207/48 ,  C07D307/28 ,  C07F15/0046 ,  C08G61/08 ,  C08G2261/3324 ,  C08G2261/418

Abstract: The subject of the present invention are novel metal complexes defined by Formula 1: The present invention also relates to methods of producing said novel metal complexes defined by Formula 1 as well as their uses.

Abstract translation: 本发明的主题是由式1定义的新型金属络合物：本发明还涉及制备由式1定义的所述新型金属络合物及其用途的方法。

公开(公告)号：US09056826B2

公开(公告)日：2015-06-16

申请号：US14130921

申请日：2012-06-28

Applicant: Anthony A. Birkbeck

Inventor： Anthony A. Birkbeck

IPC: C07C57/26 ,  C07C67/297 ,  C07C69/007 ,  C07C69/24 ,  C07C67/00 ,  C07C67/283 ,  C07C69/145 ,  C07C69/63 ,  C07C45/51 ,  C07C45/74 ,  C07C29/09

CPC classification number: C07C57/26 ,  C07C29/095 ,  C07C45/511 ,  C07C45/74 ,  C07C67/00 ,  C07C67/283 ,  C07C67/297 ,  C07C69/007 ,  C07C69/145 ,  C07C69/24 ,  C07C69/63 ,  C07C2602/42 ,  C07C69/78 ,  C07C47/225 ,  C07C33/14

Abstract: The present invention concerns a process for the preparation of a compound of formula (I) in the form of any one of its stereoisomers or mixtures thereof, and wherein R represents a C2-C10 group of formula CORa wherein Ra is an alkyl or alkenyl group optionally comprising one or two ether functional groups or is a phenyl or benzyl group optionally substituted by one to three alkyl, alkoxyl, carboxyl, acyl, amino or nitro groups or halogen atoms. The invention concerns also the use of compound (I) for the synthesis of β-santalol or of derivatives thereof.

Abstract translation: 本发明涉及制备其立体异构体或其混合物中任何一种形式的式（I）化合物的方法，其中R表示式CORa的C 2 -C 10基团，其中R a为烷基或链烯基 任选地包含一个或两个醚官能团，或者是任选被一至三个烷基，烷氧基，羧基，酰基，氨基或硝基或卤素原子取代的苯基或苄基。 本发明还涉及化合物（I）用于合成檀香醇或其衍生物的用途。

公开(公告)号：US09018408B2

公开(公告)日：2015-04-28

申请号：US13977935

申请日：2012-01-10

Applicant: William Kruper, Jr. ,  Cynthia L. Rand ,  David C. Molzahn

Inventor： William Kruper, Jr. ,  Cynthia L. Rand ,  David C. Molzahn

IPC: C07C67/00 ,  C07C69/757 ,  C07C51/377 ,  C07C63/26 ,  C07C67/297 ,  C07C67/31 ,  C07C67/327 ,  C07C69/675 ,  C07C69/82 ,  C07C67/317

CPC classification number: C07C69/757 ,  C07C51/377 ,  C07C63/26 ,  C07C67/297 ,  C07C67/31 ,  C07C67/317 ,  C07C67/327 ,  C07C69/675 ,  C07C69/82 ,  C07C69/75

Abstract: The present invention generally relates to a condensed process for producing terephthalic acid and terephthalic esters from a dialkyl cyclohexane-2,5-dione-1,4-dicarboxylate; a chemoselective process for preparing a substantially bicyclic-lactone-free dialkyl cyclohexane-2,5-diol-1,4-dicarboxylate; and compositions of matter prepared thereby.

Abstract translation: 本发明一般涉及由环己烷-2,5-二酮-1,4-二羧酸二烷基酯制造对苯二甲酸和对苯二甲酸酯的缩合方法; 用于制备基本上不含双环内酯的二烷基环己烷-2,5-二醇-1,4-二羧酸酯的化学选择性方法; 和由此制备的物质的组成。

公开(公告)号：US20140336407A1

公开(公告)日：2014-11-13

申请号：US14361174

申请日：2012-05-25

Applicant: NANJING UNIVERSITY

Inventor： Zheng Zhou ,  Zhibing Zhang ,  Gaodong Yang ,  Xionghui Gong ,  Pingkeng Wu

IPC: B01D3/00 ,  B01J8/08 ,  B01J8/02 ,  C07C29/48 ,  C07C67/297

CPC classification number: B01D3/009 ,  B01J8/005 ,  B01J8/02 ,  B01J8/08 ,  B01J8/20 ,  B01J19/18 ,  B01J2208/00557 ,  B01J2219/00006 ,  B01J2219/0004 ,  C07C29/04 ,  C07C29/48 ,  C07C67/08 ,  C07C67/297 ,  C07C2601/16 ,  Y02P20/125 ,  Y02P20/582 ,  C07C33/025 ,  C07C33/14 ,  C07C69/14

Abstract: A process of integrated system formed by coupling of fixed bed, jetting floating bed, and separating unit, aimed to provide a new process and equipment of higher efficiency, which integrates multi-type reactors and separation is provided. Reaction materials undergo preliminary reaction in fixed bed reactor and intensified reaction in jetting floating bed reactor, and then separation in the subsequent separation system. Unreacted materials will be returned to the raw material intermediate storage tank for mixing with fresh materials, as raw materials for continued reaction. During this process, materials first pass the fixed bed reactor once to achieve certain conversion rate, and then enter the jetting floating bed reactor for intensified reaction. When the product reaches required concentration, the materials will enter subsequent separation equipment for separation.

Abstract translation: 提供了一种通过固定床，喷射浮床和分离单元耦合而形成的集成系统的过程，旨在提供一种综合多型反应器和分离的更高效率的新工艺和设备。 反应材料在固定床反应器中进行预反应，并在喷射浮床反应器中加剧反应，然后在随后的分离系统中分离。 未反应的材料将返回原料中间储罐，与新鲜材料混合，作为继续反应的原料。 在此过程中，材料首先通过固定床反应器一次达到一定的转化率，然后进入喷射浮床反应器进行加强反应。 当产品达到所需浓度时，材料将进入随后的分离设备进行分离。

公开(公告)号：US20140288319A1

公开(公告)日：2014-09-25

申请号：US14055442

申请日：2013-10-16

Applicant: California Institute Of Technology

Inventor： Robert H. GRUBBS ,  Arnab K. CHATTERJEE ,  Tae-Lim CHOI ,  Steven D. GOLDBERG ,  Jennifer A. LOVE ,  John P. MORGAN ,  Daniel P. SANDERS ,  Matthias SCHOLL ,  F. Dean TOSTE ,  Tina M. TRNKA

IPC: C07F9/40 ,  C07F7/18 ,  C07D317/20 ,  C07C29/46 ,  C07C67/297 ,  C07C41/14

CPC classification number: C07F9/40 ,  C07C6/04 ,  C07C17/275 ,  C07C29/40 ,  C07C29/46 ,  C07C41/14 ,  C07C45/69 ,  C07C67/293 ,  C07C67/297 ,  C07C67/343 ,  C07C67/475 ,  C07C201/12 ,  C07C319/20 ,  C07C2531/22 ,  C07C2601/14 ,  C07C2601/16 ,  C07C2603/74 ,  C07D263/14 ,  C07D317/12 ,  C07D317/20 ,  C07D317/24 ,  C07F7/1892 ,  C07F9/4015 ,  C07F15/0046 ,  C07C25/13 ,  C07C47/21 ,  C07C69/007 ,  C07C69/78 ,  C07C69/732 ,  C07C69/56 ,  C07C321/14 ,  C07C69/16 ,  C07C69/533 ,  C07C69/145 ,  C07C69/157 ,  C07C69/18 ,  C07C205/06 ,  C07C33/483

Abstract: The invention pertains to the use of Group 8 transition metal carbene complexes as catalysts for olefin cross-metathesis reactions. In particular, ruthenium and osmium alkylidene complexes substituted with an N-heterocyclic carbene ligand are used to catalyze cross-metathesis reactions to provide a variety of substituted and functionalized olefins, including phosphonate-substituted olefins, directly halogenated olefins, 1,1,2-trisubstituted olefins, and quaternary allylic olefins. The invention further provides a method for creating functional diversity using the aforementioned complexes to catalyze cross-metathesis reactions of a first olefinic reactant, which may or may not be substituted with a functional group, with each of a plurality of different olefinic reactants, which may or may not be substituted with functional groups, to give a plurality of structurally distinct olefinic products. The methodology of the invention is also useful in facilitating the stereoselective synthesis of 1,2-disubstituted olefins in the cis configuration.

Abstract translation: 本发明涉及第8族过渡金属卡宾络合物用作烯烃交叉复分解反应的催化剂。 特别地，用N-杂环卡宾配体取代的钌和锇亚烷基配合物用于催化交叉复分解反应以提供各种取代和官能化的烯烃，包括膦酸酯取代的烯烃，直接卤代烯烃， 三取代烯烃和季烯丙烯烯烃。 本发明还提供了一种使用上述配合物来催化可能或可能不被官能团取代的第一种烯属反应物与多种不同的烯属反应物中的每一种的交叉复分解反应的方法， 或可以不被官能团取代，得到多个结构不同的烯烃产物。 本发明的方法还可用于促进顺式构型中的1,2-二取代烯烃的立体选择性合成。