公开(公告)号：US12129228B2

公开(公告)日：2024-10-29

申请号：US17433826

申请日：2019-06-11

Applicant: JILIN ASYMCHEM LABORATORIES CO., LTD.

Inventor： Hao Hong ,  Enxuan Zhang ,  Jiangping Lu ,  Fuliang Wei ,  Sihang Yang ,  Guanda Che

IPC: C07C45/68 ,  B01J19/00 ,  B01J19/12

CPC classification number: C07C45/68 ,  B01J19/0066 ,  B01J19/121 ,  B01J2219/00033 ,  C07C2602/38 ,  C07C45/68 ,  C07C49/323 ,  C07C45/68 ,  C07C49/35

Abstract: Provided is a continuous synthesis method for 1,1′-bicyclic[1.1.1]pentane-1,3-diethyl ketone compounds. The continuous synthesis method comprises: under the irradiation of a light source, continuously conveying raw material A and raw material B to a continuous reaction device for a continuous photochemical reaction to obtain 1,1′-bicyclic[1.1.1]pentane-1,3-diethyl ketone compounds, and controlling the reaction temperature in the continuous reaction device by a temperature control device during the continuous photochemical reaction. A propellane with substituents, as a reaction raw material, is subjected to the above photochemical reaction in the continuous reaction device to reduce the probability of its slow decomposition and deterioration under the irradiation, and greatly improve the conversion rate of the reaction material and product yield.

公开(公告)号：US12084411B2

公开(公告)日：2024-09-10

申请号：US17046608

申请日：2019-04-12

Applicant: The Board of Trustees of the University of Illinois

Inventor： Martin D. Burke ,  Anthony S. Grillo ,  Alexander G. Cioffi ,  Anna SantaMaria ,  Daniel Blair ,  Andrew Blake

IPC: C07C45/68 ,  A61K45/06 ,  C07C61/22

CPC classification number: C07C45/68 ,  A61K45/06 ,  C07C61/22

Abstract: Disclosed are analogues of hinokitiol, methods for preparing them, and pharmaceutical compositions thereof. Also disclosed are methods for their use in treating iron-related diseases.

公开(公告)号：US20240158340A1

公开(公告)日：2024-05-16

申请号：US18289543

申请日：2022-05-05

Applicant: Arizona Board of Regents on Behalf of the University of Arizon

Inventor： Thomas L. Gianetti ,  Md Mubarak Hossain

IPC: C07C253/30 ,  B01J31/02 ,  C07C45/68

CPC classification number: C07C253/30 ,  B01J31/0244 ,  C07C45/68

Abstract: The present invention relates to a method for producing an α-aryl substituted carbonyl compound (e.g., an α-aryl substituted cyclic ketone) from a carbonyl compound (e.g., a cyclic ketone) using an aryl halide or a heteroaryl halide and a photocatalyst (e.g., acridinium, helicenium, angulenium, or a combination thereof) in the presence of an amine compound. The method of the present invention is particularly useful in producing an α-aryl substituted carbonyl compound (e.g., an α-aryl substituted cyclic ketone) from an unactivated carbonyl compound (e.g., an unactivated cyclic ketone).

公开(公告)号：US11851384B2

公开(公告)日：2023-12-26

申请号：US17713686

申请日：2022-04-05

Applicant: Battelle Memorial Institute ,  LanzaTech, Inc.

Inventor： Karthikeyan K. Ramasamy ,  Mond Guo ,  Richard Russell Rosin ,  Joseph Anthony Kocal

IPC: C07C1/207 ,  C07C7/04 ,  C07C45/68

CPC classification number: C07C1/2076 ,  C07C7/04 ,  C07C45/68 ,  C07C2521/04 ,  C07C2521/06 ,  C07C2521/18 ,  C07C2523/44 ,  C07C2523/656

Abstract: Disclosed herein are embodiments of a method and system for converting ethanol to para-xylene. The method also provides a pathway to produce terephthalic acid from biomass-based feedstocks. In some embodiments, the disclosed method produces p-xylene with high selectivity over other aromatics typically produced in the conversion of ethanol to xylenes, such as m-xylene, ethyl benzene, benzene, toluene, and the like. And, in some embodiments, the method facilitates the ability to use ortho/para mixtures of methylbenzyaldehyde for preparing ortho/para xylene product mixtures that are amendable to fractionation to separate the para- and ortho-xylene products thereby providing a pure feedstock of para-xylene that can be used to form terephthalic anhydride and a pure feedstock of ortho-xylene that can be used for other purposes, such as phthalic anhydride.

公开(公告)号：US11739066B2

公开(公告)日：2023-08-29

申请号：US17618110

申请日：2020-06-12

Applicant: Arxada AG

Inventor： Christoph Taeschler ,  Matthias Beller ,  Helfried Neumann ,  Florian Fischer ,  Shaoke Zhang ,  Fei Ye ,  Stefan Ellinger ,  Florencio Zaragoza Doerwald

IPC: C07D295/073 ,  C07C45/68 ,  C07C67/343 ,  C07D295/067 ,  C07D317/72 ,  C07D335/02 ,  C07D451/06 ,  C07J1/00

CPC classification number: C07D295/073 ,  C07C45/68 ,  C07C67/343 ,  C07D295/067 ,  C07D317/72 ,  C07D335/02 ,  C07D451/06 ,  C07J1/0055 ,  C07J1/0062 ,  C07C2601/08 ,  C07C2601/14

Abstract: The invention discloses a method for fluoroalkylation of enamines with a fluoro alkyl halide in the presence of a base.

公开(公告)号：US20190241589A1

公开(公告)日：2019-08-08

申请号：US16284841

申请日：2019-02-25

Applicant: JOHNSON MATTHEY PUBLIC LIMITED COMPANY

Inventor： Thomas Colacot ,  Ruishan Chow ,  Andrew Jon DeAngelis

IPC: C07F15/00 ,  C07C17/32 ,  C07D215/38 ,  C07D307/46 ,  C07D213/56 ,  C07D213/50 ,  C07D213/24 ,  C07D213/127 ,  C07D295/096 ,  C07D471/04 ,  C07D409/04 ,  C07D405/04 ,  C07D403/04 ,  C07D401/06 ,  C07B43/04 ,  C07B37/04 ,  C07C45/68

CPC classification number: C07F15/006 ,  C07B37/04 ,  C07B43/04 ,  C07C17/32 ,  C07C45/68 ,  C07D213/127 ,  C07D213/24 ,  C07D213/50 ,  C07D213/56 ,  C07D215/38 ,  C07D295/096 ,  C07D307/46 ,  C07D401/06 ,  C07D403/04 ,  C07D405/04 ,  C07D409/04 ,  C07D471/04 ,  C07C49/84 ,  C07C22/08

Abstract: The present invention provides a palladium(II) complex of formula (1) or a palladium(II) complex of formula (2). R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R18, R19, R20, R21, R22, R23 and R24, m, E and X are described in the specification.The invention also provides a process for the preparation of the complexes, and their use in carbon-carbon and carbon-heteroatom coupling reactions.

公开(公告)号：US09975838B2

公开(公告)日：2018-05-22

申请号：US15453597

申请日：2017-03-08

Applicant: V. MANE FILS

Inventor： Jean-Jacques Chanot ,  Caroline Plessis

IPC: A61K8/18 ,  A61K8/00 ,  C07C49/603 ,  C07C35/18 ,  C07C69/145 ,  C07C43/188 ,  C11B9/00

CPC classification number: C07C45/61 ,  C07C29/143 ,  C07C29/40 ,  C07C35/18 ,  C07C35/21 ,  C07C41/16 ,  C07C43/188 ,  C07C45/62 ,  C07C45/68 ,  C07C45/74 ,  C07C49/403 ,  C07C49/603 ,  C07C49/613 ,  C07C49/653 ,  C07C67/08 ,  C07C69/145 ,  C07C69/157 ,  C07C2101/08 ,  C07C2101/10 ,  C07C2101/14 ,  C07C2101/16 ,  C07C2601/08 ,  C07C2601/10 ,  C07C2601/14 ,  C07C2601/16 ,  C11B9/0034 ,  C07C49/683 ,  C07C49/647 ,  C07C35/08 ,  C07C69/14

Abstract: Cyclohexenone and cyclohexenol compounds are provided having specific fragrances and remanence properties, along with methods for synthesizing these compounds, including obtaining the compound by condensing a ketone on an α-methylene-aldehyde in order to obtain, by means of a domino reaction, compounds of formula (II) as follows:

公开(公告)号：US09938253B2

公开(公告)日：2018-04-10

申请号：US14303523

申请日：2014-06-12

Applicant: Trustees of Boston College

Inventor： Amir H. Hoveyda ,  R. Kashif M. Khan ,  Sebastian Torker ,  Ming Joo Koh

IPC: C07F15/00 ,  B01J31/12 ,  C07D333/56 ,  C07F7/08 ,  C07C41/30 ,  C07C231/12 ,  C07C29/32 ,  C07D209/12 ,  C07C45/68 ,  C07C51/353 ,  C07B37/08 ,  C07C6/06 ,  C08G61/08 ,  C07F5/02 ,  B01J31/22

CPC classification number: C07D333/56 ,  B01J31/226 ,  B01J31/2273 ,  B01J31/2278 ,  B01J2231/543 ,  B01J2531/821 ,  C07B37/08 ,  C07B2200/09 ,  C07C6/06 ,  C07C29/32 ,  C07C41/30 ,  C07C45/68 ,  C07C51/353 ,  C07C231/12 ,  C07C2601/08 ,  C07C2601/14 ,  C07D209/12 ,  C07F5/025 ,  C07F7/081 ,  C07F15/0046 ,  C08G61/08 ,  C08G2261/3324 ,  C08G2261/418 ,  C07C235/30 ,  C07C33/38 ,  C07C33/50 ,  C07C43/23 ,  C07C43/166 ,  C07C33/30 ,  C07C33/025 ,  C07C47/263 ,  C07C33/02 ,  C07C59/42 ,  C07C43/178 ,  C07C49/835 ,  C07C33/14 ,  C07C33/483 ,  C07C43/176 ,  C07C33/12 ,  C07C43/162 ,  C07C13/28

Abstract: The present application provides, among other things, compounds and methods for metathesis reactions. In some embodiments, provided compounds promote highly efficient and highly Z-selective metathesis. In some embodiments, provided compounds and methods are particularly useful for producing allyl alcohols. In some embodiments, provided compounds have the structure of formula I. In some embodiments, provided compounds comprise ruthenium, and a ligand bonded to ruthenium through a sulfur atom.

公开(公告)号：US09850261B2

公开(公告)日：2017-12-26

申请号：US15326069

申请日：2015-07-16

Applicant: The Trustees of The University of Pennsylvania

Inventor： Adam T. Hoye ,  Won-Suk Kim ,  Dionicio Martinez-Solorio ,  Amos B. Smith, III ,  Rongbiao Tong ,  Minh Huu Nguyen ,  Luis Sanchez ,  Bruno Nicolas Melillo

IPC: C07D213/127 ,  C07D413/04 ,  C07F7/18 ,  C07F7/20 ,  C07C41/30 ,  C07B37/04 ,  C07B43/00 ,  C07D295/023 ,  C07C253/30 ,  C07C1/32

CPC classification number: C07F7/1804 ,  C07B37/04 ,  C07B43/00 ,  C07C1/328 ,  C07C17/263 ,  C07C41/30 ,  C07C45/68 ,  C07C67/343 ,  C07C253/30 ,  C07C2531/22 ,  C07C2601/14 ,  C07D207/323 ,  C07D213/16 ,  C07D213/26 ,  C07D213/30 ,  C07D213/38 ,  C07D213/73 ,  C07D213/74 ,  C07D213/84 ,  C07D215/04 ,  C07D233/58 ,  C07D263/57 ,  C07D295/023 ,  C07D333/08 ,  C07D413/04 ,  C07F7/20 ,  C07C25/18 ,  C07C22/08 ,  C07C15/14 ,  C07C43/205 ,  C07C43/215 ,  C07C43/2055 ,  C07C43/23 ,  C07C69/76 ,  C07C49/784 ,  C07C255/50

Abstract: Compositions and methods using silicon-based cross-coupling agents in the formation of carbon-carbon and carbon-nitrogen bonds are described.

公开(公告)号：US20170342324A1

公开(公告)日：2017-11-30

申请号：US15536682

申请日：2015-11-23

Applicant: Merck Patent GmbH

Inventor： Kevin ADLEM ,  Patricia Eileen SAXTON

IPC: C09K19/28 ,  C09K19/58 ,  C09K19/20 ,  C09K19/02 ,  C07C315/04 ,  C07C49/813 ,  C07C45/68 ,  C07C25/18 ,  C07C317/14 ,  C07C17/26 ,  C09K19/04

CPC classification number: C09K19/28 ,  C07C17/26 ,  C07C25/18 ,  C07C45/68 ,  C07C49/813 ,  C07C315/04 ,  C07C317/14 ,  C09K19/0258 ,  C09K19/14 ,  C09K19/20 ,  C09K19/2014 ,  C09K19/588 ,  C09K2019/0444

Abstract: The invention relates to bimesogenic compounds of formula I wherein R11, R12, MG11, MG12 and CG1 have the meaning given in claim 1, to the use of bimesogenic compounds of formula I in liquid crystal media and particular to flexoelectric liquid crystal devices comprising a liquid crystal medium according to the present invention.