公开(公告)号：US20240336561A1

公开(公告)日：2024-10-10

申请号：US18574693

申请日：2021-06-28

Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.

Inventor： Andreas J. VORHOLT ,  Walter LEITNER ,  Thiemo FAßBACH ,  Paul KOSSMANN

IPC: C07C263/12 ,  B01J31/18 ,  B01J31/20 ,  B01J31/24

CPC classification number: C07C263/12 ,  B01J31/189 ,  B01J31/20 ,  B01J31/2409 ,  B01J2231/763 ,  B01J2531/004 ,  B01J2531/821

Abstract: The present invention is directed towards a process for the preparation of free isocyanates, which improves upon the disadvantages associated with heterogeneous catalysis. The process comprises converting formamides into the corresponding isocyanates via a catalytic dehydrogenation, which involves bringing the formamide into contact with a Group VII, VIII or IX transition metal complex and heating.

公开(公告)号：US11873312B2

公开(公告)日：2024-01-16

申请号：US17333376

申请日：2021-05-28

Applicant: The Trustees of the University of Pennsylvania

Inventor： James Eberwine ,  Ivan J. Dmochowski ,  Sean B. Yeldell ,  Julianne C. Griepenburg ,  Teresa L. Rapp ,  Jennifer M. Singh ,  Jai-Yoon Sul ,  Jaehee Lee

IPC: C12Q1/6823 ,  C12Q1/6825 ,  C12Q1/6818 ,  C07F15/00 ,  C12N15/113 ,  C07H23/00 ,  C12N13/00 ,  B01J35/00

CPC classification number: C07F15/0053 ,  B01J35/004 ,  C07H23/00 ,  C12N13/00 ,  C12N15/113 ,  C12Q1/6818 ,  C12Q1/6823 ,  C12Q1/6825 ,  B01J2531/821 ,  C12N2310/11 ,  C12N2310/32 ,  C12N2310/3233 ,  C12N2310/351 ,  C12N2310/3517 ,  C12N2310/531

Abstract: Compositions and methods of capturing one or more nucleic acid molecules of a cell or subcellular compartment are described. In certain aspects, the compositions comprise a caged molecule comprising one or more photolinkers and an antisense oligonucleotide, which when uncaged hybridizes to a target nucleic acid molecule.

公开(公告)号：US11858948B2

公开(公告)日：2024-01-02

申请号：US16766543

申请日：2019-03-12

Applicant: Firmenich SA

Inventor： Philippe Dupau ,  Lucia Bonomo ,  Laurent Kermorvan ,  Murielle Haldimann Sanchez

IPC: C07F9/58 ,  C07F15/00 ,  C07C29/149 ,  B01J31/24 ,  B01J31/18 ,  C07B35/00 ,  C07D307/92

CPC classification number: C07F15/0053 ,  B01J31/189 ,  B01J31/2409 ,  C07B35/00 ,  C07D307/92 ,  C07F9/58 ,  B01J2231/641 ,  B01J2531/004 ,  B01J2531/821 ,  C07C29/149

Abstract: Described herein are catalytic hydrogenation processes, using Ru complexes with tetradentate ligands of formula L in hydrogenation processes for the reduction of ketone, aldehyde, ester, or lactone into the corresponding alcohol or diol respectively. These processes use a ruthenium complex of formula (1) as defined herein.

公开(公告)号：US20230398529A1

公开(公告)日：2023-12-14

申请号：US18248535

申请日：2021-10-11

Applicant: Bayer Aktiengesellschaft

Inventor： Christoph SCHOTES ,  Sébastien GOUDEDRANCE ,  Felix SPINDLER ,  Beat FUCHS

IPC: B01J31/22 ,  B01J31/18 ,  C07D221/04

CPC classification number: B01J31/2295 ,  B01J31/2217 ,  B01J31/182 ,  C07D221/04 ,  B01J2531/821 ,  B01J2531/004 ,  B01J2231/643

Abstract: The invention relates to a process for preparing optically active 2-aryl substituted 6,7-dihydro-5H-cyclopenta[b]pyridin-7-ols comprising asymmetric transfer hydrogenation of the corresponding ketones in presence of a ruthenium catalyst comprising a chiral diamine or amino alcohol ligand.

公开(公告)号：US20230391945A1

公开(公告)日：2023-12-07

申请号：US18202015

申请日：2023-05-25

Applicant: POLYSPECTRA, INC.

Inventor： Aditya BALASUBRAMANIAN ,  Raymond A. WEITEKAMP

IPC: C08G61/08 ,  B01J31/22 ,  C08K5/07 ,  C08K5/45 ,  C08K5/5313 ,  C08K5/5397 ,  G03F7/00 ,  G03F7/028 ,  G03F7/20

CPC classification number: C08G61/08 ,  B01J31/2278 ,  C08K5/07 ,  C08K5/45 ,  C08K5/5313 ,  C08K5/5397 ,  G03F7/0037 ,  G03F7/028 ,  G03F7/2004 ,  B01J2231/543 ,  B01J2531/821 ,  C08G2261/3321 ,  C08G2261/374 ,  C08G2261/418

Abstract: Described herein are compositions and methods for processing photopolymers based on olefin metathesis. The compositions and methods comprise latent ruthenium complexes and photoacids and/or photoacid generators.

公开(公告)号：US11773040B2

公开(公告)日：2023-10-03

申请号：US17060455

申请日：2020-10-01

Applicant: The Board of Trustees of The University of Alabama ,  University of South Carolina

Inventor： Elizabeth Papish ,  Aaron Vannucci

IPC: C07C1/20 ,  B01J31/18 ,  C07C41/18 ,  B01J31/22

CPC classification number: C07C41/18 ,  B01J31/181 ,  B01J31/1815 ,  B01J31/2295 ,  C07C1/20 ,  B01J2531/821 ,  C07C2601/16

Abstract: Disclosed are methods of selective hydrodeoxygenation of aromatic compounds by using catalyst systems comprising N-heterocyclic carbene (NHC) and 4-pyridinol-derived pincer ligands and metal complexes containing these ligands.

公开(公告)号：US11692056B2

公开(公告)日：2023-07-04

申请号：US16937672

申请日：2020-07-24

Applicant: PROMERUS, LLC

Inventor： Oleksandr Burtovyy ,  Wei Zhang

IPC: C08G61/12 ,  C08K3/22 ,  B01J31/22 ,  C08L65/00

CPC classification number: C08G61/122 ,  B01J31/2278 ,  C08K3/22 ,  C08L65/00 ,  B01J2531/821 ,  C08G2261/144 ,  C08G2261/147 ,  C08G2261/148 ,  C08G2261/1412 ,  C08G2261/1422 ,  C08G2261/1424 ,  C08G2261/1426 ,  C08G2261/50 ,  C08K2003/2244 ,  C08L2201/10

Abstract: Embodiments in accordance with the present invention encompass compositions encompassing a latent organo-ruthenium catalyst, an organo-ruthenium compound and a pyridine compound along with one or more monomers which undergo ring open metathesis polymerization (ROMP) when said composition is heated to a temperature from 80° C. to 150° C. or higher to form a substantially transparent film. Alternatively the compositions of this invention also undergo polymerization when subjected to suitable radiation. The monomers employed therein have a range of refractive index from 1.4 to 1.6 and thus these compositions can be tailored to form transparent films of varied refractive indices. The compositions of this invention further comprises inorganic nanoparticles which form transparent films and further increases the refractive indices of the compositions. Accordingly, compositions of this invention are useful in various opto-electronic applications, including as coatings, encapsulants, fillers, leveling agents, among others.

公开(公告)号：US11667657B2

公开(公告)日：2023-06-06

申请号：US17402905

申请日：2021-08-16

Applicant: EVONIK OPERATIONS GMBH

Inventor： Robert Franke ,  Detlef Selent ,  Armin Börner ,  Anna Chiara Sale

IPC: C07C45/50 ,  C07F9/6574 ,  B01J31/18

CPC classification number: C07F9/65746 ,  B01J31/185 ,  B01J2531/004 ,  B01J2531/821 ,  B01J2531/822 ,  B01J2531/827 ,  B01J2531/845

Abstract: New diphosphites based on cis-butene-1,4-diol.

公开(公告)号：US20230143448A1

公开(公告)日：2023-05-11

申请号：US17918634

申请日：2021-04-13

Applicant: BASF SE

Inventor： Thomas Schaub ,  Alois Kindler ,  Steffen Mader ,  A. Stephen K. Hashmi ,  Daniel James Tindall

IPC: C07C29/145 ,  B01J31/24

CPC classification number: C07C29/145 ,  B01J31/2452 ,  C07B2200/07 ,  B01J2231/641 ,  B01J2531/821

Abstract: The invention relates to a process for L-Iditol by hydrogenating L-Sorbose. Further, the invention also relates to a use of a transition metal complex as hydrogenation catalyst for L-Sorbose. The invention relates to a process for the preparation of L-Iditol comprising at least one reaction step, in which a composition comprising L-Sorbose and hydrogen is reacted in the presence of a transition metal catalyst complex in a homogeneous solution, wherein the transition metal catalyst complex comprises at least one chiral ligand containing at least one phosphorus atom, which is capable of coordinating to the transition metal, and wherein the transition metal is selected from metals of groups 8, 9 and 10 of the periodic table of the elements according to IUPAC. The invention further relates to a use of a transition metal complex as defined above and below as hydrogenation catalyst for compositions comprising L-Iditol or mixtures thereof.

公开(公告)号：US20190134618A1

公开(公告)日：2019-05-09

申请号：US16201519

申请日：2018-11-27

Applicant: HEINISCH-WESTFÄLISCHE TECHNISCHE HOCHSCHULE (RWTH) AACHEN

Inventor： Jürgen KLANKERMAYER ,  Walter Leitner ,  Markus Meuresch

IPC: B01J31/24 ,  C07D307/33 ,  C07C67/303 ,  C07C29/17 ,  C07D307/06

CPC classification number: B01J31/2409 ,  B01J2231/645 ,  B01J2531/821 ,  C07C29/177 ,  C07C67/303 ,  C07D307/06 ,  C07D307/33 ,  C07C69/34 ,  C07C31/20

Abstract: A method for the reduction organic molecules comprising a Ruthenium-Triphosphine complex with aromatic ligands at the phosphors which are ortho or meta substituted.