公开(公告)号：US20240246929A1

公开(公告)日：2024-07-25

申请号：US18556775

申请日：2022-04-19

Applicant: HUANGGANG ZY BIOTECHNOLOGY CO., LTD. ,  WUHAN RS PHARMACEUTICALS CO., LTD. ,  WUHAN QR PHARMACEUTICALS CO., LTD.

Inventor： Litao SHEN ,  Yaoxiu LIU

IPC: C07D401/04 ,  B01J31/24

CPC classification number: C07D401/04 ,  B01J31/2409 ,  B01J31/2442 ,  B01J2531/0238 ,  B01J2531/827

Abstract: A preparation method for L-nicotine involves multiple steps. The resulting L-nicotine can have an optical purity of more than 99.9%, much higher than that of similar products in the current market. The total yield of synthesis reaches 50-60%.

公开(公告)号：US20230226522A1

公开(公告)日：2023-07-20

申请号：US17995320

申请日：2021-02-24

Applicant: SABIC Global Technologies B.V.

Inventor： Byeongjin BAEK ,  Istvan LENGYEL ,  Katherine BARTON ,  Neeta KULKARNI ,  Dustin FICKEL

IPC: B01J21/04 ,  B01J35/10 ,  B01J37/02 ,  B01J37/08 ,  B01J23/652 ,  C07C4/10

CPC classification number: B01J21/04 ,  B01J35/1014 ,  B01J37/0207 ,  B01J37/0236 ,  B01J37/08 ,  B01J35/1019 ,  B01J23/6525 ,  C07C4/10 ,  B01J2531/64 ,  B01J2531/827 ,  C07C2523/652 ,  C07C2521/04

Abstract: Catalysts for the hydrogenolysis of butane are described. A supported catalyst for hydrogenolysis of butane to ethane can include a support and a catalytic crystalline bimetallic composition that can include a molybdenum-iridium (Mo—Ir) crystalline composition attached to the support. The supported catalyst has a BET specific surface area of at least 100 m2/g, preferably 100 m2/g to 500 m2/g. Method of use and methods of making the catalyst are also described.

公开(公告)号：US20230150943A1

公开(公告)日：2023-05-18

申请号：US18149740

申请日：2023-01-04

Applicant: Board of Trustees of Southern Illinois University ,  Vanderbilt University

Inventor： Boyd M. Goodson ,  Eduard Y. Chekmenev ,  Bryce E. Kidd ,  Jamil A. Mashni ,  Miranda Limbach ,  Yuqing Hou ,  Fan Shi

IPC: C07D233/60 ,  G01R33/28 ,  C07D401/06 ,  C07D241/12 ,  C07D213/63 ,  C07F9/6506 ,  B01J31/12 ,  C07D213/46

CPC classification number: C07D233/60 ,  G01R33/282 ,  C07D401/06 ,  C07D241/12 ,  C07D213/63 ,  C07F9/6506 ,  B01J31/12 ,  C07D213/46 ,  B01J2531/827 ,  G01R33/46

Abstract: The present disclosure is directed to a cleavable agent for enhanced magnetic resonance generally corresponding to the formula Y-L-R, wherein Y represents a catalyst-binding moiety having at least one isotopically labeled heteroatom, L represents a cleavable bond, and R represents a hyperpolarized payload having at least one isotopically labeled carbon. Also disclosed herein is a method of cleaving the cleavable agent for enhanced magnetic resonance.

公开(公告)号：US20190218239A1

公开(公告)日：2019-07-18

申请号：US16246872

申请日：2019-01-14

Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA

Inventor： TRAVIS J. WILLIAMS ,  JEFF JOSEPH A. CELAJE ,  ZHIYAO LU

IPC: C07F15/00 ,  B01J31/18 ,  C01B3/22 ,  B01J31/22

CPC classification number: C07F15/004 ,  B01J31/181 ,  B01J31/189 ,  B01J31/2239 ,  B01J31/2295 ,  B01J2231/763 ,  B01J2531/827 ,  C01B3/22 ,  C01B2203/0277 ,  C01B2203/1064 ,  C01B2203/1211 ,  C07F15/0033

Abstract: A formic acid decomposition catalyst system includes organometallic complexes having formula 1: wherein: M is a transition metal; E is P, N, or C (as in imidazolium carbene); R1, R2 are independently C1-6 alkyl groups; o is 1, 2, 3, or 4; R3 are independently hydrogen, C1-6 alkyl groups, OR14, NO2, halogen; R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R15, R16 are independently hydrogen or C1-6 alkyl groups; R14 is a C1-6 alkyl group; and X− is a negatively charge counter ion.

公开(公告)号：US20180099923A1

公开(公告)日：2018-04-12

申请号：US15788484

申请日：2017-10-19

Applicant: Johnson Matthey Public Limited Company

Inventor： Peter Trenton BISHOP ,  James COOKSON ,  Frederick Earnest HANCOCK ,  Steven HAWKER ,  Robert John MCNAIR

IPC: C07C209/36 ,  C07C209/62 ,  B01J31/02 ,  C07C29/17 ,  B01J31/26

CPC classification number: C07C209/365 ,  B01J31/0237 ,  B01J31/0254 ,  B01J31/26 ,  B01J2231/641 ,  B01J2231/645 ,  B01J2531/16 ,  B01J2531/17 ,  B01J2531/18 ,  B01J2531/821 ,  B01J2531/822 ,  B01J2531/824 ,  B01J2531/825 ,  B01J2531/827 ,  B01J2531/828 ,  C07C29/172 ,  C07C209/62

Abstract: The present invention relates to supported metal catalysts, wherein the catalysts are modified by at least one amine, a method for the preparation thereof and hydrogenation processes utilising the supported metal catalysts.

公开(公告)号：US20180079741A1

公开(公告)日：2018-03-22

申请号：US15786953

申请日：2017-10-18

Applicant: Takeda Pharmaceuticals Company Limited

Inventor： Masatoshi Yamada ,  Sayuri Hirano ,  Ryoji Tsuruoka ,  Mitsuhisa Yamano

IPC: C07D401/04 ,  C07F17/02 ,  B01J31/22 ,  C07F9/50 ,  C07D211/78 ,  C07D211/60 ,  C07F15/00 ,  B01J31/24

CPC classification number: C07D401/04 ,  B01J31/2226 ,  B01J31/2295 ,  B01J31/2409 ,  B01J31/2452 ,  B01J2231/645 ,  B01J2531/0205 ,  B01J2531/0263 ,  B01J2531/0266 ,  B01J2531/821 ,  B01J2531/822 ,  B01J2531/824 ,  B01J2531/827 ,  B01J2531/842 ,  B01J2540/225 ,  C07B2200/07 ,  C07D211/60 ,  C07D211/78 ,  C07F9/5027 ,  C07F15/0046 ,  C07F17/02

Abstract: The present invention provides a method of efficiently producing an optically active 6-(3-aminopiperidin-1-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine derivative. The optically active piperidine-3-carboxamide or a derivative thereof, which is obtained by subjecting 1,4,5,6-tetrahydropyridine-3-carboxamide or a derivative thereof to an asymmetric reduction in the presence of a catalyst, is used as an intermediate.

公开(公告)号：US09840451B2

公开(公告)日：2017-12-12

申请号：US14642327

申请日：2015-03-09

Applicant: Celanese International Corporation

Inventor： Jeremy J. Patt

IPC: C07C51/12 ,  C07C51/44 ,  B01J14/00 ,  B01J19/00 ,  B01D3/06 ,  B01J31/02 ,  B01J31/20

CPC classification number: C07C51/12 ,  B01D3/06 ,  B01J14/005 ,  B01J19/0013 ,  B01J31/0231 ,  B01J31/20 ,  B01J2219/00006 ,  B01J2219/00164 ,  B01J2219/00202 ,  B01J2219/00213 ,  B01J2219/0024 ,  B01J2531/822 ,  B01J2531/827 ,  C07C51/445 ,  C07C53/08

Abstract: A carbonylation process for producing acetic acid including: (a) carbonylating methanol or its reactive derivatives in the presence of a Group VIII metal catalyst and methyl iodide promoter to produce a liquid reaction mixture including acetic acid, water, methyl acetate and methyl iodide; (b) feeding the liquid reaction mixture to a flash vessel; (c) flashing the reaction mixture to produce a crude product vapor stream.

公开(公告)号：US09828400B2

公开(公告)日：2017-11-28

申请号：US15482582

申请日：2017-04-07

Applicant: Chevron U.S.A. Inc. ,  Rutgers, The State University of New Jersey

Inventor： Akshai Kumar ,  Oleg Mironov ,  Robert J. Saxton ,  Alan S. Goldman

IPC: C07C5/52 ,  C07F15/00 ,  B01J31/24

CPC classification number: C07F15/0033 ,  B01J31/2409 ,  B01J2231/766 ,  B01J2531/0244 ,  B01J2531/827 ,  C07C5/52 ,  C07C2531/24 ,  C07C11/08 ,  C07C11/02 ,  C07C11/10

Abstract: Disclosed herein are processes for dehydrogenation of an alkane to an alkene using an iridium pincer complex and iridium pincer complexes. In the dehydrogenation reactions, hydrogen that is co-formed during the process must be removed for the chemical reaction to proceed and to prevent the excess hydrogen from poisoning the catalyst. In one embodiment the process comprises providing an alkane feedstock comprising at least one alkane and contacting the alkane with an iridium pincer complex in the presence of a hydrogen acceptor selected from the group consisting of ethylene, propene, or mixtures to form an alkene product. The processes disclosed herein can accomplish facile, low-temperature transfer dehydrogenation of alkanes with unprecedented selectivities and TONs at a reasonable rate of conversion.

公开(公告)号：US09828310B2

公开(公告)日：2017-11-28

申请号：US15412523

申请日：2017-01-23

Applicant: Chevron U.S.A. Inc. ,  Rutgers, The State University of New Jersey

Inventor： Alan Stuart Goldman ,  Robert Timothy Stibrany ,  Robert J. Saxton ,  Oleg Mironov

IPC: B01J21/00 ,  B01J23/00 ,  B01J25/00 ,  B01J29/00 ,  B01J31/00 ,  C07C5/03 ,  C07C5/333 ,  C07C5/48 ,  C07C2/32 ,  C07C5/52 ,  B01J31/02 ,  B01J31/18 ,  B01J31/24

CPC classification number: C07C5/03 ,  B01J31/0208 ,  B01J31/183 ,  B01J31/2409 ,  B01J2231/20 ,  B01J2231/766 ,  B01J2531/824 ,  B01J2531/827 ,  B01J2531/828 ,  C07C2/32 ,  C07C5/333 ,  C07C5/48 ,  C07C5/52 ,  C07C2531/02 ,  C07C2531/14 ,  C07C2531/22 ,  C07C2531/24 ,  C07C11/02 ,  C07C9/00

Abstract: Provided is a Group 9 novel metal catalyst complex further comprising a ketone-containing cocatalyst. The metal catalyst complex is useful in generating olefins from alkanes with great efficiency. In one embodiment, provided is an iridium catalyst complex useful in the dehydrogenation of alkanes comprising a ketone-containing cocatalyst and iridium complexed with a tridentate ligand. Also provided is a novel dehydrogenation method which utilizes the catalyst composition. In other embodiments, a novel process for preparing oligomers from alkanes utilizing the catalyst composition is provided.

公开(公告)号：US09809569B2

公开(公告)日：2017-11-07

申请号：US15125299

申请日：2015-03-13

Applicant: Takeda Pharmaceutical Company Limited

Inventor： Masatoshi Yamada ,  Sayuri Hirano ,  Ryoji Tsuruoka ,  Mitsuhisa Yamano

IPC: C07D401/04 ,  C07D211/60 ,  C07D211/78 ,  C07F17/02 ,  B01J31/24 ,  C07F9/50 ,  C07F15/00 ,  B01J31/22

CPC classification number: C07D401/04 ,  B01J31/2226 ,  B01J31/2295 ,  B01J31/2409 ,  B01J31/2452 ,  B01J2231/645 ,  B01J2531/0205 ,  B01J2531/0263 ,  B01J2531/0266 ,  B01J2531/821 ,  B01J2531/822 ,  B01J2531/824 ,  B01J2531/827 ,  B01J2531/842 ,  B01J2540/225 ,  C07B2200/07 ,  C07D211/60 ,  C07D211/78 ,  C07F9/5027 ,  C07F15/0046 ,  C07F17/02

Abstract: The present invention provides a method of efficiently producing an optically active 6-(3-aminopiperidin-1-yl)-2,4-dioxo -1,2,3,4-tetrahydropyrimidine derivative.The optically active piperidine-3-carboxamide or a derivative thereof, which is obtained by subjecting 1,4,5,6-tetrahydropyridine -3-carboxamide or a derivative thereof to an asymmetric reduction in the presence of a catalyst, is used as an intermediate.